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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
SKLNRGNIVEFIGGIFDRRGDEEYLGEPVTMAEHMLQGATIAEQNGQPEEIIVGALLHDIGHFTSEFGMFYHEEAGAEVL
EQFFPSVITDCVRYHVAAKRYLCATKPEYFNRLSEASIHSLKLQGGPMDAEEVAEFEKNPNLKQIIAVRYLDEAGKRADM
ETPDYWHFAPMVQRMVDKHMG

The query sequence (length=181) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 6npa:A 188 188 0.9945 0.9574 0.9574 3.74e-133 6npa:B, 6npa:C, 6npa:D
2 4mlm:A 188 180 0.3425 0.3298 0.3444 3.26e-35 4mlm:B, 4mln:A, 4mln:B, 4n6w:A, 4n71:A, 4n71:B, 4n71:D, 4n71:E
3 9ash:A 753 54 0.1160 0.0279 0.3889 0.072 9asi:A, 6xn3:A, 6xn4:A, 6xn5:A, 6xn7:A
4 8dek:B 441 81 0.1160 0.0476 0.2593 1.4 8dek:A, 8df2:A, 8df2:B, 8df2:C, 8df2:D
5 6kaf:C 450 91 0.1436 0.0578 0.2857 1.4 8bd3:C, 8bd3:c, 6kac:C, 6kac:c, 6kad:C, 6kad:c, 6kaf:c, 7pi0:C, 7pi0:c, 7pi5:C, 7pi5:c, 7pin:C, 7pin:c, 7pin:C1, 7pin:c1, 7piw:C, 7piw:c, 7piw:C1, 7piw:c1, 7pnk:C, 7pnk:c, 8r2i:C
6 8kde:C 430 91 0.1436 0.0605 0.2857 1.5 8zee:C
7 5xnl:C 450 122 0.1713 0.0689 0.2541 2.0 8c29:C, 8c29:c, 3jcu:C, 3jcu:c, 5mdx:C, 5mdx:c, 7oui:C, 7oui:c, 5xnl:c, 5xnm:C, 5xnm:c, 6yp7:c, 6yp7:C
8 1zkp:A 251 44 0.0773 0.0558 0.3182 2.5 1zkp:B, 1zkp:C, 1zkp:D
9 6nud:J 741 53 0.1105 0.0270 0.3774 3.9 6ifk:A, 6ifn:A, 6ify:A, 6ifz:A, 6ig0:A, 6nue:J
10 7v02:F 650 48 0.0939 0.0262 0.3542 4.3
11 6o7i:A 741 31 0.0663 0.0162 0.3871 5.0
12 7k0s:A 4110 68 0.1105 0.0049 0.2941 5.5 7k0s:B, 7k0s:D, 7k0s:C, 7k0t:A, 7k0t:B, 7k0t:D, 7k0t:C
13 5tb3:B 4196 68 0.1105 0.0048 0.2941 5.8 7aih:UB, 7am2:U5, 7am2:U2, 7ane:UB, 7aoi:UK, 6bbm:W, 6c5l:BJ, 6c5l:DJ, 9f1c:BK, 7f4v:aJ, 7f4v:bJ, 7f4v:cJ, 6fg3:A, 6fg3:B, 6fg3:C, 6fg3:D, 1fka:Q, 1fka:T, 5gan:x, 6h8k:Y, 6h8k:j, 6hiv:AB, 6hix:AB, 5j4z:H, 5j4z:E, 5j4z:F, 5j4z:I, 5j7y:H, 5j7y:E, 5j7y:F, 5j7y:I, 5j8k:H, 5j8k:E, 5j8k:F, 5j8k:I, 6jlu:N, 6jlu:n, 7jmf:B, 7jmf:E, 7jmf:G, 7jmf:I, 7jmg:B, 7jmg:E, 7jmg:I, 7jmg:G, 7jmh:B, 7jmh:E, 7jmh:G, 7jmh:I, 7jmi:B, 7jmi:E, 7jmi:G, 7jmi:I, 7jmj:B, 7jmj:E, 7jmj:G, 7jmj:I, 5jpq:n, 5jpq:C, 7l8w:H, 5lc5:P, 5ldw:P, 5ldx:P, 7lh5:BJ, 7lh5:DJ, 5lj3:x, 5lj5:x, 5luf:E, 5luf:F, 5luf:G, 5luf:I, 5nvs:I, 5nvs:K, 5nvs:J, 5nvs:L, 5nvu:K, 5nvu:M, 5nvu:L, 5nvu:N, 2o01:K, 6o1o:B, 6o1o:C, 6o1o:D, 6o1o:E, 6o1o:I, 6o1o:J, 6o1o:K, 5o31:P, 5ot7:l, 7pkq:D, 7pkt:X, 7pkt:C, 7pub:U7, 7pub:UE, 6pv6:B, 6pv6:E, 6pv6:I, 6pv6:G, 1pyh:C, 1pyh:E, 1pyh:K, 1pyh:S, 1pyh:Y, 6q95:H, 7qwq:s, 5t15:B, 5t15:E, 5t15:I, 5t15:G, 5t9m:B, 5t9m:E, 5t9m:I, 5t9m:G, 5t9n:B, 5t9n:E, 5t9n:I, 5t9n:G, 5t9r:B, 5t9r:E, 5t9r:I, 5t9r:G, 5t9s:B, 5t9s:E, 5t9s:I, 5t9s:G, 5t9v:B, 5t9v:G, 5t9v:I, 5t9v:E, 5ta3:B, 5ta3:G, 5ta3:I, 5ta3:E, 5tal:B, 5tal:G, 5tal:I, 5tal:E, 5tam:B, 5tam:E, 5tam:I, 5tam:G, 5tan:B, 5tan:E, 5tan:I, 5tan:G, 5tap:B, 5tap:E, 5tap:I, 5tap:G, 5taq:B, 5taq:E, 5taq:I, 5taq:G, 5tas:B, 5tas:I, 5tas:E, 5tas:G, 5tat:B, 5tat:I, 5tat:E, 5tat:G, 5tau:B, 5tau:I, 5tau:E, 5tau:G, 5tav:B, 5tav:E, 5tav:I, 5tav:G, 5taw:B, 5taw:G, 5taw:I, 5taw:E, 5tax:B, 5tax:I, 5tax:G, 5tax:E, 5tay:B, 5tay:G, 5tay:I, 5tay:E, 5taz:B, 5taz:I, 5taz:G, 5taz:E, 5tb0:B, 5tb0:G, 5tb0:E, 5tb0:I, 5tb1:B, 5tb1:I, 5tb1:E, 5tb1:G, 5tb2:B, 5tb2:I, 5tb2:E, 5tb2:G, 5tb3:E, 5tb3:I, 5tb3:G, 5tb4:B, 5tb4:E, 5tb4:I, 5tb4:G, 7tdh:A, 7tdh:B, 7tdh:C, 7tdh:D, 8tug:M, 8tvp:M, 8tvq:M, 8tvs:M, 8tye:L, 5tzs:y, 5tzs:n, 5tzs:o, 4uq8:E, 4uq8:F, 4uq8:G, 4uq8:I, 4v3p:SW, 4v3p:LL, 4v5e:BJ, 4v5e:DJ, 4v5f:BJ, 4v5f:BL, 4v5f:Bl, 4v5f:DJ, 4v5f:DL, 4v5f:Dl, 4v5g:BJ, 4v5g:DJ, 4v5j:BJ, 4v5j:DJ, 4v5k:BJ, 4v5k:DJ, 4v5l:BJ, 4v5p:BJ, 4v5p:DJ, 4v5q:BJ, 4v5q:DJ, 4v5r:BJ, 4v5r:DJ, 4v5s:BJ, 4v5s:DJ, 4v6i:AW, 4v6i:Ab, 4v6i:BL, 4v7r:Ab, 4v7r:Ac, 4v7r:Ad, 4v7r:Ah, 4v7r:Bh, 4v7r:Cb, 4v7r:Cc, 4v7r:Cd, 4v7r:Ch, 4v7r:Dh, 4v8n:BJ, 4v8n:DJ, 4v8o:BJ, 4v8q:AJ, 4v8u:BJ, 4v8u:DJ, 4v8x:BJ, 4v8x:DJ, 4v90:BJ, 4v9h:BJ, 4v9h:BL, 4v9i:BJ, 4v9i:DJ, 4v9j:BJ, 4v9j:DJ, 4v9k:BJ, 4v9k:DJ, 4v9l:BJ, 4v9l:DJ, 4v9m:BJ, 4v9m:DJ, 7vd5:5, 6w1s:G, 4w29:BJ, 4w29:DJ, 8wb4:g, 8wb4:G, 5wlc:SX, 6wmt:K, 4wt8:CJ, 4wt8:DJ, 5wyj:AA, 5wyj:UA, 5wyj:UB, 5wyk:AA, 5wyk:UA, 5wyk:UB, 4wz7:Z, 4wz7:AN, 8xkl:G, 6xyw:BI, 6xyw:BJ, 6xyw:BK, 7y3f:K, 6z1p:AD, 6z1p:BC, 5zep:0, 6zm5:v
14 7umz:A 3927 68 0.1105 0.0051 0.2941 5.8 6g4s:s, 6g4w:s, 5j4z:G, 5j7y:G, 5j8k:G, 5tzs:Q, 7umz:D, 7umz:B, 7umz:C, 5wyj:UC, 5wyj:AG, 5wyk:AG, 5wyk:UC, 4wz7:A, 6xyw:AP
15 6foo:A 4168 68 0.1105 0.0048 0.2941 5.9 5dat:m2, 5dc3:m2, 5dgv:m2, 5fci:m2, 5fcj:m2, 6foo:B, 6foo:C, 6foo:D, 5i4l:m2, 5it7:KK, 6j3z:20, 6j3z:21, 5j4z:B, 6j40:20, 6j40:40, 6j40:21, 6j40:41, 8j5k:4, 8j5k:9, 5j7y:B, 5j8k:B, 7lh5:BK, 7lh5:DK, 5luf:B, 5lyb:m2, 5mrc:dd, 5mre:dd, 5mrf:dd, 5obm:m2, 5on6:m2, 5ot7:m, 7pkq:V, 7pkt:Y, 6q95:I, 5tga:m2, 5tzs:Z, 5tzs:m, 4u3m:m2, 4u3n:m2, 4u3u:m2, 4u4n:m2, 4u4o:m2, 4u4q:m2, 4u4r:m2, 4u4u:m2, 4u4y:m2, 4u4z:m2, 4u50:m2, 4u51:m2, 4u52:m2, 4u53:m2, 4u55:m2, 4u56:m2, 4u6f:m2, 4uq8:B, 6uz7:AK, 4v3p:SG, 4v5g:BK, 4v5g:DK, 4v5l:BK, 4v5p:BK, 4v5p:DK, 4v5q:BK, 4v5q:DK, 4v5r:BK, 4v5r:DK, 4v5s:BK, 4v5s:DK, 4v6i:AG, 4v88:DK, 4v8o:BK, 4v8q:AK, 4v8t:K, 4v8y:BK, 4v8z:BK, 4v90:BK, 8w4p:4, 6woo:K, 7y1a:A, 7y5e:A8, 7y5e:AC, 7y7a:AN, 7y7a:AY, 5z3g:d
16 5xyi:I 166 30 0.0552 0.0602 0.3333 6.0
17 7tdg:A 4134 68 0.1105 0.0048 0.2941 6.1 7tdg:C, 7tdg:D, 7tdg:B, 7tdi:B, 7tdi:C, 7tdi:D, 7tdi:A, 7tdj:A, 7tdj:B, 7tdj:C, 7tdj:D, 7tdk:A, 7tdk:B, 7tdk:C, 7tdk:D
18 7t65:A 4252 68 0.1105 0.0047 0.2941 6.2 7t64:A, 7t64:B, 7t64:C, 7t64:D, 7t65:B, 7t65:C, 7t65:D
19 6wot:A 4197 68 0.1105 0.0048 0.2941 6.5 6wot:B, 6wot:C, 6wot:D
20 7tzc:A 4404 68 0.1105 0.0045 0.2941 6.7 3rqr:A, 8sen:A, 8sen:B, 8sen:C, 8sen:D, 8seo:A, 8seo:B, 8seo:C, 8seo:D, 8sep:A, 8sep:B, 8sep:C, 8sep:D, 8seq:A, 8seq:B, 8seq:C, 8seq:D, 8ser:A, 8ser:B, 8ser:C, 8ser:D, 8ses:A, 8ses:B, 8ses:C, 8ses:D, 8set:A, 8set:B, 8set:C, 8set:D, 7tzc:B, 7tzc:G, 7tzc:I
21 1ssg:A 247 45 0.0829 0.0607 0.3333 7.7 1ssg:B, 1su5:A, 1su5:B, 1sw0:A, 1sw0:B, 1sw3:A, 1sw3:B, 1sw7:A, 1sw7:B, 1tpb:1, 1tpb:2, 1tpc:1, 1tpc:2, 1tph:1, 1tph:2, 1tpu:A, 1tpu:B, 1tpv:A, 1tpv:B, 1tpw:A, 1tpw:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218