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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
SKFLDRFRYFKQKGETFADGHGQLLNTNRDWEDGYRQRWQHDKIVRSTHGVGSCSWKIYVKNGLVTWETQQTDYPRTRPD
LPNHEPRGCPRGASYSWYLYSANRLKYPMMRKRLMKMWREAKALHSDPVEAWASIIEDADKAKSFKQARGRGGFVRSSWQ
EVNELIAASNVYTIKNYGPDRVAGFSPIPAMSMVSYASGARYLSLIGGTCLSFYDWYCDLPPASPQTWGEQTDVPESADW
YNSSYIIAWGSNVPQTRTPDAHFFTEVRYKGTKTVAVTPDYAEIAKLCDLWLAPKQGTDAAMALAMGHVMLREFHLDNPS
QYFTDYVRRYTDMPMLVMLEERDGYYAAGRMLRAADLVDALGQENNPEWKTVAFNTNGEMVAPNGSIGFRWGEKGKWNLE
QRDGKTGEETELQLSLLGSQDEIAEVGFPYFGGDGTEHFNKVELENVLLHKLPVKRLQLADGSTALVTTVYDLTLANYGL
ERGLNDVNCATSYDDVKAYTPAWAEQITGVSRSQIIRIAREFADNADKTHGRSMIIVGAGLNHWYHLDMNYRGLINMLIF
CGCVGQSGGGWAHYVGQEKLRPQTGWQPLAFALDWQRPARHMNSTSYFYNHSSQWRYETVTAEELLSPMADKSRYTGHLI
DFNVRAERMGWLPSAPQLGTNPLTIAGEAEKAGMNPVDYTVKSLKEGSIRFAAEQPENGKNHPRNLFIWRSNLLGSSGKG
HEFMLKYLLGTEHGIQGKDLGQQGGVKPEEVDWQDNGLEGKLDLVVTLDFRLSSTCLYSDIILPTATWYEKDDMNTSDMH
PFIHPLSAAVDPAWEAKSDWEIYKAIAKKFSEVCVGHLGKETDIVTLPIQHDSAAELAQPLDVKDWKKGECDLIPGKTAP
HIMVVERDYPATYERFTSIGPLMEKIGNGGKGIAWNTQSEMDLLRKLNYTKAEGPAKGQPMLNTAIDAAEMILTLAPETN
GQVAVKAWAALSEFTGRDHTHLALNKEDEKIRFRDIQAQPRKIISSPTWSGLEDEHVSYNAGYTNVHELIPWRTLSGRQQ
LYQDHQWMRDFGESLLVYRPPIDTRSVKEVIGQKSNGNQEKALNFLTPHQKWGIHSTYSDNLLMLTLGRGGPVVWLSEAD
AKDLGIADNDWIEVFNSNGALTARAVVSQRVPAGMTMMYHAQERIVNLPGSEITQQRGGIHNSVTRITPKPTHMIGGYAH
LAYGFNYYGTVGSNRDEFVVVRKMKNIDWLDGEGNDQVQE

The query sequence (length=1240) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 3egw:A 1244 1243 0.9984 0.9952 0.9960 0.0 3ir5:A, 3ir6:A, 3ir7:A, 1q16:A, 1r27:A, 1r27:C, 1siw:A, 1y4z:A, 1y5i:A, 1y5l:A, 1y5n:A
2 5chc:A 895 802 0.1976 0.2737 0.3055 4.36e-92 5ch7:A, 5ch7:C, 5ch7:E, 5chc:C, 5chc:E, 5e7o:A, 5e7o:C, 5e7o:E, 5e7o:G, 5e7o:I, 5e7o:K, 4ydd:A, 4ydd:C, 4ydd:E
3 5chc:A 895 237 0.0653 0.0905 0.3418 5.24e-33 5ch7:A, 5ch7:C, 5ch7:E, 5chc:C, 5chc:E, 5e7o:A, 5e7o:C, 5e7o:E, 5e7o:G, 5e7o:I, 5e7o:K, 4ydd:A, 4ydd:C, 4ydd:E
4 2ivf:A 912 331 0.0710 0.0965 0.2659 6.56e-24
5 2ivf:A 912 173 0.0395 0.0537 0.2832 1.12e-08
6 2ivf:A 912 73 0.0218 0.0296 0.3699 2.61e-07
7 7b04:B 1120 360 0.0750 0.0830 0.2583 1.61e-23 7b04:E, 7b04:H, 7b04:K, 7b04:N, 7b04:Q, 7b04:T, 7b04:W
8 7b04:B 1120 136 0.0258 0.0286 0.2353 0.11 7b04:E, 7b04:H, 7b04:K, 7b04:N, 7b04:Q, 7b04:T, 7b04:W
9 7b04:B 1120 265 0.0476 0.0527 0.2226 0.14 7b04:E, 7b04:H, 7b04:K, 7b04:N, 7b04:Q, 7b04:T, 7b04:W
10 2vpw:A 734 269 0.0540 0.0913 0.2491 1.33e-09 2vpw:E, 2vpx:A, 2vpx:E, 2vpy:A, 2vpy:E, 2vpz:A, 2vpz:E
11 2vpw:A 734 71 0.0177 0.0300 0.3099 0.010 2vpw:E, 2vpx:A, 2vpx:E, 2vpy:A, 2vpy:E, 2vpz:A, 2vpz:E
12 2vpw:A 734 84 0.0218 0.0368 0.3214 0.49 2vpw:E, 2vpx:A, 2vpx:E, 2vpy:A, 2vpy:E, 2vpz:A, 2vpz:E
13 1dmr:A 779 266 0.0516 0.0822 0.2406 2.68e-08 1dms:A, 2dmr:A, 3dmr:A, 4dmr:A, 1e18:A, 1e5v:A, 1e5v:C, 1e60:A, 1e60:C, 1e61:A, 1e61:C, 1h5n:A, 1h5n:C
14 1dmr:A 779 74 0.0202 0.0321 0.3378 2.85e-06 1dms:A, 2dmr:A, 3dmr:A, 4dmr:A, 1e18:A, 1e5v:A, 1e5v:C, 1e60:A, 1e60:C, 1e61:A, 1e61:C, 1h5n:A, 1h5n:C
15 1dmr:A 779 126 0.0282 0.0449 0.2778 0.017 1dms:A, 2dmr:A, 3dmr:A, 4dmr:A, 1e18:A, 1e5v:A, 1e5v:C, 1e60:A, 1e60:C, 1e61:A, 1e61:C, 1h5n:A, 1h5n:C
16 7bkb:D 549 292 0.0573 0.1293 0.2432 7.28e-07 7bkb:d, 7bkc:D, 7bkc:d, 7bkd:D, 7bke:D
17 7bkb:D 549 70 0.0226 0.0510 0.4000 8.23e-06 7bkb:d, 7bkc:D, 7bkc:d, 7bkd:D, 7bke:D
18 8cm5:A 974 273 0.0532 0.0678 0.2418 7.67e-07 8bqg:A, 8bqh:A, 8bqi:A, 8bqj:A, 8bqk:A, 8bql:A, 8cm4:A, 8cm4:C, 8cm5:C, 8cm5:K, 8cm5:R, 8cm6:A, 8cm6:C, 8cm7:A, 8rc8:A, 8rc9:A, 8rca:A, 8rcb:A, 8rcc:A, 8rcg:A, 6sdr:A, 6sdv:A, 7z5o:AAA
19 1eu1:A 767 284 0.0548 0.0887 0.2394 7.86e-07
20 1eu1:A 767 74 0.0194 0.0313 0.3243 1.10e-06
21 1eu1:A 767 100 0.0234 0.0378 0.2900 6.48e-04
22 1eu1:A 767 78 0.0210 0.0339 0.3333 0.24
23 1tmo:A 794 85 0.0242 0.0378 0.3529 1.35e-06
24 1tmo:A 794 46 0.0169 0.0264 0.4565 8.37e-04
25 7l5s:A 771 71 0.0177 0.0285 0.3099 2.82e-05 7l5i:A
26 7l5s:A 771 368 0.0613 0.0986 0.2065 0.003 7l5i:A
27 7l5s:A 771 164 0.0306 0.0493 0.2317 0.073 7l5i:A
28 7l5s:A 771 86 0.0185 0.0298 0.2674 1.5 7l5i:A
29 1fdi:A 715 69 0.0185 0.0322 0.3333 3.10e-05 1aa6:A, 1fdo:A, 2iv2:X, 7z0t:A
30 1fdi:A 715 169 0.0323 0.0559 0.2367 5.89e-04 1aa6:A, 1fdo:A, 2iv2:X, 7z0t:A
31 1fdi:A 715 86 0.0210 0.0364 0.3023 0.017 1aa6:A, 1fdo:A, 2iv2:X, 7z0t:A
32 2e7z:A 727 175 0.0339 0.0578 0.2400 6.59e-05
33 2e7z:A 727 80 0.0194 0.0330 0.3000 0.11
34 4v4c:A 875 319 0.0597 0.0846 0.2320 1.85e-04 4v4c:C, 4v4c:E, 4v4c:G, 4v4c:I, 4v4c:K, 4v4c:M, 4v4c:O, 4v4c:Q, 4v4c:S, 4v4c:U, 4v4c:W, 4v4d:A, 4v4d:C, 4v4d:E, 4v4d:G, 4v4d:I, 4v4d:K, 4v4d:M, 4v4d:O, 4v4d:Q, 4v4d:S, 4v4d:U, 4v4d:W, 4v4e:A, 4v4e:C, 4v4e:E, 4v4e:G, 4v4e:I, 4v4e:K, 4v4e:M, 4v4e:O, 4v4e:Q, 4v4e:S, 4v4e:U, 4v4e:W
35 4v4c:A 875 83 0.0202 0.0286 0.3012 0.057 4v4c:C, 4v4c:E, 4v4c:G, 4v4c:I, 4v4c:K, 4v4c:M, 4v4c:O, 4v4c:Q, 4v4c:S, 4v4c:U, 4v4c:W, 4v4d:A, 4v4d:C, 4v4d:E, 4v4d:G, 4v4d:I, 4v4d:K, 4v4d:M, 4v4d:O, 4v4d:Q, 4v4d:S, 4v4d:U, 4v4d:W, 4v4e:A, 4v4e:C, 4v4e:E, 4v4e:G, 4v4e:I, 4v4e:K, 4v4e:M, 4v4e:O, 4v4e:Q, 4v4e:S, 4v4e:U, 4v4e:W
36 7qv7:S 571 69 0.0194 0.0420 0.3478 2.82e-04 7qv7:Y
37 7qv7:S 571 186 0.0323 0.0701 0.2151 0.001 7qv7:Y
38 7qv7:S 571 86 0.0177 0.0385 0.2558 0.003 7qv7:Y
39 1h0h:A 977 99 0.0226 0.0287 0.2828 3.48e-04 1h0h:K
40 2v45:A 723 189 0.0371 0.0636 0.2434 0.003 2jim:A, 2jio:A, 2jip:A, 2jiq:A, 2jir:A, 2nap:A, 2v3v:A
41 1kqf:A 982 262 0.0435 0.0550 0.2061 0.003 1kqg:A
42 6cz7:A 814 275 0.0484 0.0737 0.2182 0.023 6cz7:C, 6cz8:C, 6cz8:A, 6cz9:A, 6cz9:C, 6cza:A, 6cza:C
43 6cz7:A 814 31 0.0113 0.0172 0.4516 2.6 6cz7:C, 6cz8:C, 6cz8:A, 6cz9:A, 6cz9:C, 6cza:A, 6cza:C
44 7vw6:A 913 71 0.0169 0.0230 0.2958 0.10 7e5z:A, 8j83:A, 7xqw:A
45 7vw6:A 913 100 0.0202 0.0274 0.2500 0.89 7e5z:A, 8j83:A, 7xqw:A
46 7vw6:A 913 91 0.0202 0.0274 0.2747 2.5 7e5z:A, 8j83:A, 7xqw:A
47 3ml1:A 799 77 0.0210 0.0325 0.3377 0.23 3o5a:A
48 7xp7:B 376 69 0.0153 0.0505 0.2754 0.50 7xp7:A, 7xp7:C, 7xp7:D
49 8gym:s1 689 54 0.0153 0.0276 0.3519 0.90 8b6f:AB, 8bqs:AB, 8gym:S1, 8gzu:s1, 8gzu:S1, 7tgh:S1
50 6tg9:A 949 43 0.0137 0.0179 0.3953 1.2 6tg9:E, 6tga:A, 6tga:E
51 6tg9:A 949 69 0.0161 0.0211 0.2899 2.1 6tg9:E, 6tga:A, 6tga:E
52 3szy:A 413 77 0.0161 0.0484 0.2597 9.0 3szz:A, 3t00:A, 3t01:A, 3t02:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218