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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
SINPPQRIVFVGLGTIAQSFLPLLSKVHDLSTLEIYAIDPKTPPLIEYFANSFGLKFINSAIDQINYRDILVPILGEGTV
LINLSTDVSSLALIELCRSAGALYLDTCIEPWKGGYDDPTIPLHKRTNYHLREQMLSLKKRLGSGVTALVAHGANPGLVS
HFVKRALLDLAEEILGDCKKPSNKEQWAILSQRLGVKVIHVAEYDSQISQKSRERGEFVNTWSVHGFISESQQPAELGWG
SHERSLPTDASMHTDGCGAAIYIEKPGASVRVKTWTPFNGPSLGYLVTHHEAISIADFLTLRTADETYRPTVHYAYRPSD
EAILSVHEWFGNDCMTPEKTKVLRPGDILSGSDYLGVLLMGHEKSSYWYGSILSIEKAKELATLNTATTLQVAAGVLSGY
LWILSHPSAGIIEAEDMDHEVALSYISQYLGELKGVYSDWNPTKNNSDSPWLFSNFVL

The query sequence (length=458) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 6y87:A 470 466 1.0000 0.9745 0.9828 0.0 6y87:B, 6y87:C, 6y87:D, 6y87:E, 6y87:F
2 4plp:A 475 465 0.4585 0.4421 0.4516 8.85e-140 4plp:B, 6s3x:A, 6s3x:B, 6s49:A, 6s49:B, 6s4d:A, 6s4d:B, 6s65:A, 6s65:B, 6s6g:A, 6s6g:B, 6s72:A, 6s72:B, 6sep:A, 6sep:B, 4tvb:A, 4tvb:B, 4xq9:A, 4xq9:B, 4xqc:A, 4xqc:B, 4xqe:A, 4xqe:B, 4xqg:A, 4xqg:B, 4xr4:A, 4xr4:B, 4xrg:A, 4xrg:B
3 2ph5:A 459 461 0.4345 0.4336 0.4317 4.47e-130
4 4rl6:A 414 179 0.0852 0.0942 0.2179 0.034 4rl6:B
5 8deb:A 397 225 0.1048 0.1209 0.2133 1.5 8deb:B
6 2c03:B 297 40 0.0262 0.0404 0.3000 2.2 2c03:A, 2cnw:A, 2cnw:B, 2cnw:C, 2j7p:A, 2j7p:B, 1jpj:A, 1jpn:B, 1jpn:A, 1ls1:A, 1ng1:A, 2ng1:A, 1o87:A, 1o87:B, 1okk:A
7 8p5d:LA0 245 37 0.0284 0.0531 0.3514 2.4 8p60:LA0, 8p60:KA0, 7qca:LA0
8 4eso:B 251 58 0.0437 0.0797 0.3448 3.7 4eso:A, 4eso:C, 4eso:D
9 7ofx:B 665 86 0.0568 0.0391 0.3023 4.4 7ofx:A, 7ofx:C, 7ofx:D, 5ohs:A, 5ohs:B, 5ohs:C, 5ohs:D, 5ohs:E, 5ohs:F, 5ohs:G, 5ohs:H, 5ohy:A, 5ohy:B, 5ohy:C, 5ohy:D
10 2q3r:A 351 76 0.0437 0.0570 0.2632 4.5 1vji:A
11 8esq:l 174 40 0.0349 0.0920 0.4000 7.2 8esr:l
12 2c5s:A 372 39 0.0262 0.0323 0.3077 8.0
13 6t62:A 244 53 0.0349 0.0656 0.3019 8.2 6t62:B, 6wpr:A, 6wpr:B
14 8he6:B 120 35 0.0306 0.1167 0.4000 8.5
15 1qax:A 425 48 0.0328 0.0353 0.3125 9.3 8gdn:A, 8gdn:B, 4i4b:A, 4i4b:B, 4i56:A, 4i56:B, 4i6a:A, 4i6a:B, 4i6w:A, 4i6w:B, 4i6y:A, 4i6y:B, 1qax:B, 1qay:A, 1qay:B, 1r31:A, 1r31:B, 8sz6:A, 8sz6:B, 1t02:A, 8vlq:A, 8vlq:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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