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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
SIKELAVDEELAAADGLIPRQKSKLCKHGDRGMCEYCSPLPPWDKEYHEKNKIKHISFHSYLKKLNENANKKENGSSYIS
PLSEPDFRINKRCHNGHEPWPRGICSKCQPSAITLQQQEFRMVDHVEFQKSEIINEFIQAWRYTGMQRFGYMYGSYSKYD
NTPLGIKAVVEAIYEPPQHDEQDGLTMDVEQVKNEMLQIDRQAQEMGLSRIGLIFTDLSDAGAGDGSVFCKRHKDSFFLS
SLEVIMAARHQTRHPNVSKYSEQGFFSSKFVTCVISGNLEGEIDISSYQVSTEAEALVTADMISGSTFPSMAYINDTTDE
RYVPEIFYMKSNEYGITVKENAKPAFPVDYLLVTLTHGFPNTTNSKFVSSTGFPWSNRQAMGQSQDYQELKKYLFNVASS
GDFNLLHEKISNFHLLLYINSLQILSPDEWKLLIESAVKNEWEESLLKLVSSAGWQTLVMILQESG

The query sequence (length=466) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 8dau:G 475 468 0.9914 0.9726 0.9872 0.0 8dar:G, 8das:G, 8dat:G, 8dav:G, 8daw:G, 6jwh:A, 6jwi:A, 6jwi:E, 6jwj:A, 6oa9:G
2 6chs:A 460 465 0.5021 0.5087 0.5032 1.35e-171 6cdd:A, 6cdd:B
3 7wwp:A 420 470 0.3412 0.3786 0.3383 2.99e-86 7wwq:A
4 7sa3:A 303 89 0.0644 0.0990 0.3371 0.39
5 2pom:A 355 75 0.0494 0.0648 0.3067 1.1
6 6kpm:A 295 38 0.0300 0.0475 0.3684 1.2 6kpn:A, 6kpo:A
7 2atx:A 186 49 0.0343 0.0860 0.3265 1.6 2atx:B
8 8jng:A 147 29 0.0258 0.0816 0.4138 2.0
9 6en3:A 934 79 0.0472 0.0236 0.2785 2.5 8a49:C, 4nuy:A, 4nuz:A
10 6e93:A 112 74 0.0408 0.1696 0.2568 3.2 6e94:A
11 6yoz:AAA 400 97 0.0536 0.0625 0.2577 4.2 1ojj:A, 1ojj:B, 1ojk:A, 1ojk:B, 6yoz:BBB
12 4v3p:ST 82 44 0.0258 0.1463 0.2727 5.3
13 2g49:A 970 84 0.0494 0.0237 0.2738 6.3 6b3q:A, 6b3q:B, 6b70:A, 6b70:B, 6bfc:A, 6bfc:B, 6byz:A, 6byz:B, 5cjo:A, 3cww:B, 3cww:A, 4dtt:A, 4dtt:B, 4dwk:A, 4dwk:B, 3e4a:A, 3e4a:B, 3e4z:A, 3e4z:B, 3e50:A, 3e50:B, 6eds:A, 6eds:B, 2g47:A, 2g47:B, 2g48:A, 2g48:B, 2g49:B, 2g54:A, 2g54:B, 2g56:A, 2g56:B, 4gs8:A, 4gs8:B, 4gsc:A, 4gsc:B, 4gsf:A, 4gsf:B, 3h44:A, 3h44:B, 3hgz:A, 3hgz:B, 4ifh:A, 4ifh:B, 2jbu:A, 2jbu:B, 2jg4:A, 2jg4:B, 7k1d:A, 7k1d:B, 7k1e:A, 7k1e:B, 7k1f:A, 7k1f:B, 4lte:A, 4lte:B, 4m1c:A, 4m1c:B, 6mq3:A, 6mq3:B, 3n56:A, 3n56:B, 3n57:A, 3n57:B, 4nxo:A, 4nxo:B, 3ofi:A, 3ofi:B, 3p7l:A, 3p7o:A, 4pes:A, 4pes:B, 4pf7:A, 4pf7:B, 4pf9:A, 4pf9:B, 4pfc:A, 4pfc:B, 4qia:A, 4qia:B, 3qz2:A, 3qz2:B, 4ral:A, 4ral:B, 4re9:A, 4re9:B, 7rze:A, 7rzf:A, 7rzi:A, 7rzi:B, 3tuv:A, 2wby:A, 2wby:B, 2wc0:A, 2wc0:B, 2wk3:A, 2wk3:B, 5wob:A, 5wob:B, 5wob:C, 5wob:D, 5wob:E, 5wob:F, 5wob:G, 5wob:H, 2ypu:A, 2ypu:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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