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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
SIFPKISLRPEVENYLKEGFMNKEIVTALGKQEAERKFETLLKHLSHPPSFTTVRVNTHLASVQHVKNLLLDELQKQFNG
LSVPILQHPDLQDVLLIPVIGPRKNIKKQQCEAIVGAQCGNAVLRGAHVYAPGIVSASQFMKAGDVISVYSDIKGKCKKG
AKEFDGTKVFLGNGISELSRKEIFSGLPELKGMGIRMTEPVYLSPSFDSVLPRYLFLQNLPSALVSHVLNPQPGEKILDL
CAAPGGKTTHIAALMHDQGEVIALDKIFNKVEKIKQNALLLGLNSIRAFCFDGTKAVKGEPPFLPESFDRILLDAPCSGM
GQRPNMACTWSVKEVASYQPLQRKLFTAAVQLLKPEGVLVYSTCTITLAENEEQVAWALTKFPCLQLQPQEPQIGGEGMR
GAGLSCEQLKQLQRFDPSAVPLPDTDMDSLREARREDMLRLANKDSIGFFIAKFVKC

The query sequence (length=457) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 5wwr:A 461 461 1.0000 0.9913 0.9913 0.0 5wwr:B, 5wws:A, 5wws:B, 5wwt:A, 5wwt:B
2 5zve:B 384 394 0.2735 0.3255 0.3173 1.78e-50 5zve:A, 5zvg:B, 5zvg:A, 5zvh:B, 5zvh:A
3 2yxl:A 443 182 0.1488 0.1535 0.3736 8.23e-31
4 8fkt:SY 378 264 0.1926 0.2328 0.3333 2.56e-27 8fku:SY, 8fkv:SY, 8fkw:SY, 8fkx:SY, 8fky:SY
5 8esq:q 341 264 0.1882 0.2522 0.3258 2.73e-27
6 3a4t:A 258 178 0.1422 0.2519 0.3652 5.36e-26 3a4t:B
7 8v87:q 371 264 0.1860 0.2291 0.3220 3.21e-25 6elz:q, 6em5:q, 7nac:q, 7ohr:q, 7r7a:q, 7r7c:q, 8v83:q, 8v84:q
8 8esr:q 260 261 0.1794 0.3154 0.3142 1.18e-23
9 3m6w:A 460 181 0.1532 0.1522 0.3867 1.60e-22 3m6v:A, 3m6v:B
10 8i9w:CP 356 268 0.1991 0.2556 0.3396 7.08e-22 8i9r:CP, 8i9t:CP, 8i9v:CP, 8i9x:CP, 8i9y:CP, 8i9z:CP, 8ia0:CP
11 1sqf:A 425 182 0.1335 0.1435 0.3352 2.50e-19
12 2b9e:A 275 188 0.1313 0.2182 0.3191 4.44e-15
13 7of5:C 338 180 0.1247 0.1686 0.3167 2.05e-12 7of0:C, 7of3:C, 7of7:C
14 7pd3:x 366 180 0.1247 0.1557 0.3167 2.92e-12 4fp9:A, 4fp9:C, 4fp9:D, 4fp9:F, 4fzv:A, 7o9k:A1, 7o9m:A1, 7odr:x, 7ods:x, 7odt:x, 7oic:x, 8pk0:x, 8qsj:x
15 7r6k:q 177 170 0.1116 0.2881 0.3000 9.12e-10
16 2cww:B 382 140 0.0875 0.1047 0.2857 3.49e-07 2cww:A
17 2bh2:A 418 91 0.0591 0.0646 0.2967 0.005 2bh2:B, 1uwv:A
18 7pnx:b 326 103 0.0656 0.0920 0.2913 0.009 8ipk:A, 8ipl:A, 8ipm:D, 7pny:b, 7pnz:b, 8qrl:8
19 4dmg:A 385 138 0.0853 0.1013 0.2826 0.057 4dmg:B
20 1eiz:A 180 34 0.0284 0.0722 0.3824 0.14 1ej0:A
21 2b3t:A 276 141 0.0788 0.1304 0.2553 0.15 1t43:A
22 6rjb:B 622 99 0.0569 0.0418 0.2626 0.34 6ha3:A, 6had:A, 4kxu:A, 4kxv:A, 4kxw:A, 4kxx:A, 4kxy:A, 4kxy:B, 3mos:A, 3ooy:A, 3ooy:B, 6rjb:A, 8wa8:A, 8wa9:A, 8wa9:B, 8waa:A, 8waa:B
23 1jg1:A 215 93 0.0525 0.1116 0.2581 0.44 1jg2:A, 1jg3:A, 1jg3:B, 1jg4:A
24 7pnv:b 323 103 0.0656 0.0929 0.2913 0.53
25 4o29:A 207 82 0.0416 0.0918 0.2317 1.7
26 5oql:S 237 34 0.0284 0.0549 0.3824 4.1 6rxt:CB, 6rxu:CB, 6rxv:CB, 6rxx:CB, 6rxy:CB, 6rxz:CB
27 1dl5:A 317 108 0.0547 0.0789 0.2315 4.6 1dl5:B
28 3c46:A 1095 172 0.1028 0.0429 0.2733 6.8 3c2p:A, 3c2p:B, 3c3l:A, 3c3l:B, 3c46:B, 4ff1:A, 4ff1:B, 4ff2:A, 4ff2:B, 4ff3:A, 4ff3:B, 4ff4:A, 4ff4:B, 3q0a:A, 3q0a:B, 3q22:A, 3q22:B, 3q23:A, 3q23:B, 3q24:A, 3q24:B
29 7uu5:A 379 48 0.0372 0.0449 0.3542 6.9 8e40:A, 8edj:A, 5k81:A, 5k81:B, 5k81:C, 5k81:D, 5k81:E, 5k81:F, 5k82:A, 5k82:B, 5k82:C, 5k82:D, 5k83:C, 5k83:E, 5k83:A, 5k83:D, 5k83:F, 5k83:B, 6p3x:A, 6p3x:B, 6p3y:A, 6p3y:B, 6p3z:A, 6p3z:B, 6p40:A, 6p40:B, 7uu3:A, 7uu3:B, 7uu4:A, 7uu5:B
30 4bju:A 548 112 0.0591 0.0493 0.2411 8.7 4bju:B, 5o9x:A, 5oaw:A, 5oaw:B
31 2j28:9 430 58 0.0372 0.0395 0.2931 9.3 5aka:5
32 6b3t:A 396 89 0.0503 0.0581 0.2584 9.6 6b0u:A, 6b0u:B, 6b0u:C, 8d1r:A, 8d23:A, 8d25:A, 5ebv:A, 5ec4:A, 8f4a:A, 8f4t:A, 8f4u:A, 8f4w:A, 8f4z:A, 8f51:A, 8f55:A, 8f57:A, 8f58:A, 5iv0:A, 4jd6:A, 4jd6:B, 4jd6:C, 4jd6:D, 4jd6:E, 4jd6:F, 6p3t:A, 6p3u:A, 6p3v:A, 3r1k:A, 3ryo:A, 3ryo:B, 3ryo:C, 3ryo:D, 3ryo:E, 3ryo:F, 3ryo:G, 3ryo:H, 3ryo:I, 3ryo:J, 3ryo:K, 3ryo:L, 5tvj:A, 6vur:A, 6vus:A, 6vut:A, 6vuu:A, 6vuw:A, 6vux:A, 6vuy:A, 6vuz:A, 6vv0:A, 6vv1:A, 6vv2:A, 6vv3:A, 6x10:A, 6x6g:AAA, 6x6i:AAA, 6x6y:AAA, 6x7a:AAA

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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