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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
SHMRVLVCGGAGYIGSHFVRALLRDTNHSVVIVDSLVGTHGKSDHVETRENVARKLQQSDGPKPPWADRYAALEVGDVRN
EDFLNGVFTRHGPIDAVVHMCAFLAVGESVRDPLKYYDNNVVGILRLLQAMLLHKCDKIIFSSSAAIFGNPTNAEPIDIN
AKKSPESPYGESKLIAERMIRDCAEAYGIKGICLRYFNACGAHEDGDIGEHYQGSTHLIPIILGRVMSDIAPDDKRMPIF
GTDYPTPDGTCVRDYVHVCDLASAHILALDYVEKLGPNDKSKYFSVFNLGTSRGYSVREVIEVARKTTGHPIPVRECGRR
EGDPAYLVAASDKAREVLGWKPKYDTLEAIMETSWKFQRTHPNGYA

The query sequence (length=366) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 1gy8:C 370 370 1.0000 0.9892 0.9892 0.0 2cnb:A, 2cnb:B, 2cnb:C, 2cnb:D, 1gy8:A, 1gy8:B, 1gy8:D
2 2c20:A 329 361 0.4044 0.4498 0.4100 5.96e-86 2c20:B, 2c20:C, 2c20:D, 2c20:E, 2c20:F
3 4twr:A 325 350 0.3907 0.4400 0.4086 5.51e-74 4wok:A
4 1a9y:A 338 366 0.3934 0.4260 0.3934 2.05e-72 1a9z:A, 5gy7:A, 5gy7:B, 1kvq:A, 1kvr:A, 1kvs:A, 1kvt:A, 1kvu:A, 1lrj:A, 1lrk:A, 1lrl:A, 1nah:A, 1nai:A, 1uda:A, 1udb:A, 1udc:A, 2udp:A, 2udp:B, 1xel:A
5 6k0g:A 335 365 0.4016 0.4388 0.4027 8.70e-70 6k0h:A, 6k0i:A
6 3enk:A 340 363 0.4071 0.4382 0.4105 1.96e-69 3enk:B
7 7k3p:A 329 358 0.3525 0.3921 0.3603 4.70e-69 7k3p:B
8 7kn1:A 336 360 0.3770 0.4107 0.3833 1.37e-67 7kn1:B
9 8wov:B 341 363 0.3798 0.4076 0.3829 2.13e-64 8wop:A, 8wop:B, 8wov:A, 8wow:A, 8wow:B
10 1i3k:A 347 366 0.3743 0.3948 0.3743 3.32e-64 1ek5:A, 1ek6:A, 1ek6:B, 1hzj:A, 1hzj:B, 1i3k:B, 1i3l:A, 1i3l:B, 1i3m:A, 1i3m:B, 1i3n:A, 1i3n:B
11 7xpo:A 344 364 0.3825 0.4070 0.3846 1.09e-63 7xpo:B, 7xpp:B, 7xpp:A, 7xpq:A, 7xpq:B
12 4lis:A 364 379 0.3634 0.3654 0.3509 5.68e-62 4lis:B, 4lis:C
13 1z45:A 674 367 0.3415 0.1855 0.3406 6.73e-43
14 4zrn:A 309 360 0.3087 0.3657 0.3139 7.81e-40 4zrm:A, 4zrm:B, 4zrn:B
15 2p5u:A 311 358 0.3087 0.3633 0.3156 1.04e-29 2p5u:B, 2p5u:C, 2p5u:D, 2p5y:A
16 6wj9:B 308 333 0.2596 0.3084 0.2853 6.58e-28 6wj9:A, 6wja:A, 6wja:B, 6wjb:A, 6wjb:B
17 6dnt:A 310 355 0.2514 0.2968 0.2592 9.44e-28
18 6zll:A 321 363 0.2705 0.3084 0.2727 2.89e-24 6zl6:A, 6zl6:B, 6zla:A, 6zla:B, 6zla:C, 6zla:D, 6zld:A, 6zld:B, 6zlj:A, 6zlj:B, 6zlk:A, 6zlk:B, 6zlk:C, 6zlk:D, 6zll:B, 6zll:C, 6zll:D
19 6bwl:A 313 354 0.2350 0.2748 0.2429 9.50e-23
20 1sb8:A 341 346 0.2514 0.2698 0.2659 3.34e-19 1sb9:A
21 6bi4:C 311 358 0.2322 0.2733 0.2374 1.12e-18 6bi4:B, 6bi4:D, 6bi4:A
22 3ehe:A 290 346 0.2322 0.2931 0.2457 7.23e-18 3ehe:B
23 1keu:A 361 374 0.2514 0.2548 0.2460 1.73e-17 1g1a:A, 1g1a:B, 1g1a:C, 1g1a:D, 1keu:B, 1kew:A, 1kew:B
24 3aw9:A 304 362 0.2350 0.2829 0.2376 5.26e-17 3aw9:B, 3aw9:C, 3icp:A, 3ko8:A
25 1r66:A 322 358 0.2486 0.2826 0.2542 8.22e-17 1r6d:A
26 8du1:A 361 380 0.2486 0.2521 0.2395 1.10e-16 8du1:B, 8du1:C, 8du1:D
27 8sk0:B 330 365 0.2514 0.2788 0.2521 4.98e-16 8shh:A, 8shh:B, 8sk0:A
28 1bxk:B 344 271 0.1940 0.2064 0.2620 1.01e-15 1bxk:A
29 2hun:A 329 354 0.2350 0.2614 0.2429 1.81e-15 2hun:B
30 6pnl:A 336 351 0.2377 0.2589 0.2479 3.38e-15 6pmh:A
31 6vlo:A 319 305 0.2158 0.2476 0.2590 1.27e-14 6vlo:B, 6vlo:C, 6vlo:D
32 7yst:A 312 361 0.2678 0.3141 0.2715 9.43e-14 7ys8:A, 7ys8:B, 7ys9:A, 7ys9:B, 7ysa:A, 7ysa:B, 7ysm:A, 7ysm:B, 7yst:B, 7ysy:A, 7ysy:B, 7yt0:A, 7yt0:B
33 1ker:B 347 364 0.2350 0.2478 0.2363 1.15e-13 1kep:A, 1kep:B, 1ker:A, 1ket:A, 1ket:B, 1oc2:A, 1oc2:B
34 2b69:A 312 346 0.1995 0.2340 0.2110 1.31e-13 4gll:A, 4gll:B
35 1orr:A 338 381 0.2295 0.2485 0.2205 4.17e-13 1orr:B, 1orr:C, 1orr:D
36 6kv9:A 299 363 0.2486 0.3043 0.2507 1.09e-12 6kvc:A
37 3lu1:A 336 357 0.2350 0.2560 0.2409 1.22e-12 3lu1:B, 3lu1:C, 3lu1:D, 3ru7:A, 3ru7:B, 3ru7:C, 3ru7:D, 3ru9:A, 3ru9:B, 3ru9:C, 3ru9:D, 3rua:A, 3rua:B, 3rua:C, 3rua:D, 3ruc:A, 3ruc:B, 3ruc:C, 3ruc:D, 3rud:A, 3rud:B, 3rud:C, 3rud:D, 3rue:A, 3rue:B, 3rue:S, 3rue:b, 3ruf:A, 3ruf:B, 3ruf:S, 3ruf:b, 3ruh:A, 3ruh:B, 3ruh:C, 3ruh:D
38 5z75:A 306 195 0.1530 0.1830 0.2872 3.72e-12 5z75:B, 5z75:D
39 2q1s:A 336 343 0.2104 0.2292 0.2245 3.72e-12 2pzj:A, 2q1t:A, 2q1u:A, 2q1u:B
40 5u4q:B 304 316 0.2077 0.2500 0.2405 8.04e-12
41 3vps:A 303 328 0.2158 0.2607 0.2409 3.87e-11 3vps:B
42 2pzm:A 316 367 0.2568 0.2975 0.2561 4.55e-11 2pzk:A, 2pzk:B, 2pzl:A, 2pzl:B, 2pzm:B
43 4ej0:A 330 320 0.2158 0.2394 0.2469 7.73e-11 4ej0:B, 4ej0:C, 4ej0:D, 4ej0:E, 4ej0:F, 4ej0:G, 4ej0:H, 4ej0:I, 4ej0:J
44 5u4q:A 321 316 0.1967 0.2243 0.2278 1.53e-10
45 6x3b:A 300 269 0.1721 0.2100 0.2342 2.28e-10 6x3b:B, 6x3b:C, 6x3b:D
46 4id9:B 328 286 0.1776 0.1982 0.2273 3.23e-10 4id9:A, 4idg:A, 4idg:B
47 8vr2:B 321 361 0.2213 0.2523 0.2244 6.40e-10 8vr2:A, 8vr2:C, 8vr2:D
48 2pk3:A 309 367 0.2240 0.2654 0.2234 1.63e-09 2pk3:B
49 6bwc:C 327 202 0.1448 0.1621 0.2624 1.95e-09 6bwc:A, 6bwc:B, 6bwc:D, 6bwc:E, 6bwc:F
50 3sxp:D 314 308 0.1831 0.2134 0.2175 4.86e-09 3sxp:A, 3sxp:B, 3sxp:C, 3sxp:E
51 7kf3:A 362 283 0.2049 0.2072 0.2650 5.23e-09 7kf3:B, 7kf3:C, 7kf3:D
52 2x6t:G 308 332 0.2240 0.2662 0.2470 6.72e-09 1eq2:B, 1eq2:D, 1eq2:E, 1eq2:F, 1eq2:G, 1eq2:H, 1eq2:I, 1eq2:J, 2x6t:A, 2x6t:B, 2x6t:C, 2x6t:D, 2x6t:E, 2x6t:F, 2x6t:H, 2x6t:I, 2x6t:J, 2x86:A, 2x86:B, 2x86:C, 2x86:D, 2x86:E, 2x86:F, 2x86:G, 2x86:H, 2x86:I, 2x86:J, 2x86:K, 2x86:L, 2x86:M, 2x86:N, 2x86:O, 2x86:P, 2x86:Q, 2x86:R, 2x86:S, 2x86:T
53 1eq2:A 273 303 0.2049 0.2747 0.2475 7.63e-09 1eq2:C
54 3a1n:A 315 193 0.1366 0.1587 0.2591 1.58e-08 3a1n:B, 3a4v:A, 3a4v:B, 3a9w:A, 3a9w:B, 3ajr:A, 3ajr:B
55 4pvd:A 342 299 0.1940 0.2076 0.2375 6.45e-08 4pvd:B
56 1bsv:A 317 250 0.1366 0.1577 0.2000 1.11e-07 1bws:A, 1e6u:A, 1e7q:A, 1e7r:A, 1e7s:A, 1fxs:A
57 1n7g:B 336 260 0.1967 0.2143 0.2769 1.34e-07 1n7g:A, 1n7g:C, 1n7g:D, 1n7h:A, 1n7h:B
58 2z1m:A 338 265 0.1858 0.2012 0.2566 3.97e-07 2z1m:D, 2z95:A, 2z95:D
59 7cgv:A 310 194 0.1366 0.1613 0.2577 7.92e-07 7cgv:B, 7cgv:C, 7cgv:D
60 7eps:A 310 193 0.1311 0.1548 0.2487 8.42e-06 7eps:B, 7eps:C, 7eps:D, 3wmx:A, 3wmx:B, 3wmx:C, 3wmx:D
61 8gjh:A 639 386 0.2240 0.1283 0.2124 9.49e-06 8gjh:B, 8gjh:C, 8gjh:D, 8gjh:E, 8gjh:F
62 8v4h:B 342 362 0.1967 0.2105 0.1989 1.44e-05 8v4g:A, 8v4g:B, 8v4h:A
63 4lk3:B 274 344 0.1831 0.2445 0.1948 1.48e-05 4lk3:A, 4lk3:C, 4lk3:D, 4lk3:E, 4lk3:F, 4m55:A, 4m55:B, 4m55:C, 4m55:D
64 5y1f:A 311 362 0.2186 0.2572 0.2210 2.29e-05 5y1e:A, 5y1g:A
65 1rkx:C 351 290 0.1885 0.1966 0.2379 3.07e-05 1rkx:A, 1rkx:B, 1rkx:D
66 7epr:B 310 196 0.1311 0.1548 0.2449 4.42e-05 7epr:A, 7epr:C, 7epr:D
67 5in4:A 355 273 0.1831 0.1887 0.2454 1.66e-04 6gpj:A, 6gpj:B, 6gpj:D, 6gpj:C, 6gpk:A, 6gpk:B, 6gpk:C, 6gpk:D, 6gpl:B, 6gpl:E, 6gpl:C, 6gpl:D, 5in4:B, 5in4:C, 5in4:D, 5in5:A, 5in5:B, 5in5:C, 5in5:D, 6q94:B, 6q94:A, 6q94:C, 6q94:E, 6q94:D, 6q94:F, 6q94:G, 6q94:H, 1t2a:A, 1t2a:D, 1t2a:B, 1t2a:C
68 2gn4:A 329 202 0.1366 0.1520 0.2475 1.81e-04 2gn4:B, 2gn6:A, 2gn6:B, 2gn8:A, 2gn8:B, 2gn9:A, 2gn9:B, 2gna:A, 2gna:B
69 8du0:A 286 270 0.1557 0.1993 0.2111 3.47e-04 7ll6:A
70 6jyg:D 307 194 0.1311 0.1564 0.2474 4.59e-04 6jyg:A, 6jyg:B, 6jyg:C, 6jyg:E, 6jyg:F
71 1z7e:D 644 237 0.1366 0.0776 0.2110 5.45e-04 2bln:A, 2bln:B, 5j63:A, 5j63:B, 5j63:C, 5j63:D, 1z7e:A, 1z7e:B, 1z7e:C, 1z7e:E, 1z7e:F
72 6kwt:A 338 373 0.2350 0.2544 0.2306 7.56e-04
73 3rfv:A 265 102 0.0738 0.1019 0.2647 0.002 3rfv:B, 3rfv:C, 3rfx:A, 3rfx:B, 3rfx:C
74 7c1e:A 342 106 0.0820 0.0877 0.2830 0.002 7c1e:B, 7c3v:A, 5z2x:A, 5z2x:B, 8zav:A, 8zav:B, 5zec:A, 5zec:B, 5zed:A, 5zed:B
75 6vo6:D 311 383 0.2240 0.2637 0.2141 0.002 6vo6:A, 6vo6:B, 6vo6:C, 6vo8:A, 6vo8:B
76 2c59:A 364 366 0.2022 0.2033 0.2022 0.002 2c54:A, 2c54:B, 2c59:B, 2c5a:A, 2c5a:B, 2c5e:A, 2c5e:B, 8sg0:A, 8sg0:B, 8skb:A, 8skb:B, 8skb:C, 8skb:D
77 7ymb:A 343 293 0.1776 0.1895 0.2218 0.003
78 6h0n:A 377 395 0.2049 0.1989 0.1899 0.008 6h0n:B, 6h0p:A, 6h0p:B
79 4m55:E 164 44 0.0492 0.1098 0.4091 0.010
80 3st7:A 369 40 0.0437 0.0434 0.4000 0.019 2zkl:A
81 1i24:A 392 140 0.1202 0.1122 0.3143 0.019 1i2b:A, 1i2c:A, 1qrr:A
82 2yy7:A 312 200 0.1311 0.1538 0.2400 0.039 2yy7:B
83 7cxt:A 348 256 0.1530 0.1609 0.2188 0.045 7anc:A, 7cxt:B, 7m13:A, 7m13:B
84 5uzh:A 345 243 0.1585 0.1681 0.2387 0.072
85 3m2p:B 255 206 0.1202 0.1725 0.2136 0.098
86 1wvg:A 352 57 0.0519 0.0540 0.3333 0.11 1wvg:B
87 1rpn:D 322 301 0.1995 0.2267 0.2425 0.13 1rpn:A, 1rpn:B, 1rpn:C
88 7anc:B 314 236 0.1339 0.1561 0.2076 0.16
89 3wmw:B 278 130 0.0902 0.1187 0.2538 0.21 3wmw:A
90 3w1v:A 347 186 0.1120 0.1182 0.2204 0.24 4g5h:A, 3vvc:A, 3w1v:B
91 3vvb:A 270 186 0.1120 0.1519 0.2204 0.31
92 3p19:A 239 82 0.0656 0.1004 0.2927 0.56 3p19:B, 3p19:C, 3p19:D
93 8hku:L24P 122 89 0.0656 0.1967 0.2697 0.58 8hkv:L24P, 8hky:L24P, 8hkz:L24P, 8hl1:L24P, 8hl2:L24P, 8hl3:L24P, 8hl4:L24P, 8hl5:L24P
94 3pvz:B 300 199 0.1202 0.1467 0.2211 0.91
95 7csa:A 310 35 0.0410 0.0484 0.4286 1.2 7csa:B, 7csa:C, 7csa:D, 7csb:C, 7csb:D, 7csb:A, 7csb:B, 7csc:E, 7csc:F, 7csc:A, 7csc:B, 7csc:C, 7csc:D, 7csd:C, 7csd:D, 7csd:A, 7csd:B, 7cse:E, 7cse:F, 7cse:A, 7cse:B, 7cse:C, 7cse:D, 7csf:C, 7csf:D, 7csf:A, 7csf:B
96 3pvz:A 372 218 0.1339 0.1317 0.2248 1.3 3pvz:C, 3pvz:D
97 4yr9:A 308 114 0.0847 0.1006 0.2719 1.5 4yr9:B, 4yr9:C, 4yr9:D, 4yr9:E, 4yr9:F
98 4b4o:A 295 32 0.0410 0.0508 0.4688 1.8 4b4o:B, 4b4o:C, 4b4o:D, 4b4o:E, 4b4o:F, 4b4o:G, 4b4o:H
99 3c3x:A 310 21 0.0273 0.0323 0.4762 2.3 3c3x:B, 2qw8:A, 2qw8:B, 2qx7:A, 2qx7:B, 2qzz:A, 2qzz:B, 2r2g:A, 2r2g:B, 2r6j:A, 2r6j:B
100 7tm7:A 802 80 0.0683 0.0312 0.3125 3.9 7tm7:B
101 6nki:A 356 30 0.0301 0.0309 0.3667 4.7
102 8fem:A 327 20 0.0328 0.0367 0.6000 6.0 8fen:A
103 1vl0:A 281 185 0.1202 0.1566 0.2378 6.5 1vl0:B, 1vl0:C
104 2uzh:C 155 67 0.0546 0.1290 0.2985 6.5 2uzh:A, 2uzh:B
105 4lfl:A 142 91 0.0738 0.1901 0.2967 7.4 4lfl:C, 4lfm:A, 4lfm:C, 4lfn:A, 4lfn:C
106 6rie:O 822 73 0.0492 0.0219 0.2466 7.4 4ckb:A, 4ckb:D, 4ckc:A, 4ckc:D, 4cke:A, 4cke:D, 2vdw:A, 2vdw:C, 2vdw:E, 2vdw:G
107 7y7u:A 288 46 0.0355 0.0451 0.2826 7.9 7y7u:B
108 7cs6:F 300 29 0.0355 0.0433 0.4483 8.6 7cs3:A, 7cs3:B, 7cs3:C, 7cs3:D, 7cs3:E, 7cs3:F, 7cs4:E, 7cs4:A, 7cs4:F, 7cs4:D, 7cs4:C, 7cs4:B, 7cs5:E, 7cs5:A, 7cs5:F, 7cs5:D, 7cs5:C, 7cs5:B, 7cs6:A, 7cs6:B, 7cs6:C, 7cs6:D, 7cs6:E, 7cs7:A, 7cs7:B, 7cs7:C, 7cs7:D, 7cs7:E, 7cs7:F, 7cs8:A, 7cs8:B, 7cs8:C, 7cs8:D, 7cs8:E, 7cs8:F
109 6tmf:D 184 58 0.0492 0.0978 0.3103 8.7
110 5a7y:B 278 53 0.0492 0.0647 0.3396 9.1 5a7y:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218