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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
SHMEFKVIAEYFDKLEKISSRLQLTALLADLLSKSDKTIIDKVVYIIQGKLWPDFLGYPELGIGEKFLIKAISIATNTDE
NSVENLYKTIGDLGEVARRLKSKQQSTGILGFLGTTSKESLTVDEVYSTLSKVALTTGEGSRDLKIRLLAGLLKKADPLE
AKFLVRFVEGRLRVGIGDATVLDAMAIAFGGGQSASEIIERAYNLRADLGNIAKIIVEKGIEALKTLKPQVGIPIRPMLA
ERLSNPEEILKKMGGNAIVDYKYDGERAQIHKKEDKIFIFSRRLENITSQYPDVVDYVSKYIEGKEFIIEGEIVAIDPES
GEMRPFQELMHRKRKSDIYEAIKEYPVNVFLFDLMYYEDVDYTTKPLEARRKLLESIVKPNDYVKIAHHIQANNVEDLKS
FFYRAISEGGEGVMVKAIGKDAIYQAGARGWLWIKLKRD

The query sequence (length=439) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 7rpx:E 590 437 0.9954 0.7407 1.0000 0.0 2hix:A, 7rpo:E, 7rpw:E
2 6wbo:A 555 438 0.4032 0.3189 0.4041 7.40e-97
3 2cfm:A 561 437 0.3964 0.3102 0.3982 1.90e-93
4 3gde:A 551 438 0.3713 0.2958 0.3721 1.68e-83
5 4eq5:A 516 435 0.3531 0.3004 0.3563 6.17e-78
6 8vzl:A 646 473 0.3326 0.2260 0.3087 8.87e-56 9bs3:A, 9bs3:E, 9bs4:A, 9bs4:E, 7kr3:A, 7kr4:A, 7l34:A, 7l35:A, 6p09:A, 6p0a:A, 6p0b:A, 6p0c:A, 6p0d:A, 6p0e:A, 6q1v:A, 7qnz:A, 7qo1:A, 7sum:A, 7sx5:A, 7sxe:A, 8vdn:A, 8vds:A, 8vdt:A, 8vzm:A, 1x9n:A
7 3l2p:A 535 431 0.2551 0.2093 0.2599 1.48e-30
8 7lsy:Y 855 330 0.1913 0.0982 0.2545 1.27e-17 6bkg:A, 4htp:A, 4htp:B, 3w1b:A, 3w1g:A, 3w5o:A, 3w5o:B
9 6bkf:A 562 330 0.1822 0.1423 0.2424 1.18e-15
10 1vs0:B 305 176 0.0957 0.1377 0.2386 9.45e-07 6nhx:A, 6nhz:A, 1vs0:A
11 6ras:I 433 266 0.1549 0.1570 0.2556 1.11e-04 6rar:I, 6rau:I, 6rce:I
12 7jil:T 85 94 0.0638 0.3294 0.2979 0.45
13 3rbf:A 443 34 0.0364 0.0361 0.4706 1.5 3rch:B
14 8ora:A 480 34 0.0364 0.0333 0.4706 1.6 8or9:A
15 4oxd:A 185 108 0.0638 0.1514 0.2593 3.6 4d0y:A, 4d0y:B, 4nt9:B, 4nt9:A, 4nt9:C, 4ox5:A, 4oxd:C, 4oxd:B, 4oxd:E, 4oxd:D
16 5cxw:A 376 29 0.0228 0.0266 0.3448 4.8
17 5vc7:A 544 102 0.0661 0.0533 0.2843 5.0 5vc7:C, 5vc7:D, 5vc7:E, 5vc7:F, 5vc7:G
18 2zyj:A 397 195 0.0934 0.1033 0.2103 5.3 3cbf:A, 3cbf:B, 2egy:A, 2egy:B, 2egy:C, 2egy:D, 2z1y:A, 2z1y:B, 2zp7:A, 2zp7:C, 2zp7:B, 2zp7:D, 2zp7:E, 2zp7:F, 2zyj:B
19 1flg:A 582 29 0.0319 0.0241 0.4828 5.5 1flg:B
20 6rm3:LO0 173 34 0.0364 0.0925 0.4706 5.9
21 8fli:B 458 67 0.0569 0.0546 0.3731 7.9 6me0:C, 6mec:C
22 8bx8:C 3947 46 0.0364 0.0041 0.3478 8.9 7k58:C, 7k5b:C, 7kek:C
23 7ql6:C 427 45 0.0342 0.0351 0.3333 8.9 8esk:B, 8f2s:B, 8f6y:B, 8f6z:B, 7ql5:C, 7smq:B, 7sms:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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