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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
SHGQSCLGCVVLVSVIEQLAEVHNSSVQVAMERLCSYLPEKLFLKTACYFLVQTFGSDIIKLLDEAMKADVVCYALEFCK
RGAVQCHLYPLPQEAWESALEKARQVLRRICSLPFLTKICQKIELSIKKAVPFKDVDSDKHSVFPTLRGYHWRGRDCNDS
DKTVYPGRRPDNWDIHQDSNCNGIWGIDPKDGIPYEKKFCEGSQPRGIILLGDAAGAHFHIPPEWLTASQMSVNSFLNLP
SALTDELNWPQLSGVTGFLDSTSGIEEKSIYHRLRKRNHCNHRDYQSISKNGASSRNLKNFIESLSRNQASDHPAIVLYA
MIGNDVCNSKADTVPEMTTPEQMYANVMQTLTHLNSHLPNGSHVILYGLPDGTFLWDSLHNRYHPLGQLNKDVTYAQFFS
FLRCLQLNPCNGWMSSNKTLRTLTSERAEQLSNTLKKIATTETFANFDLFYVDFAFHEIIEDWQKRGGQPWQLIEPVDGF
HPNEVASLLQANRVWEKIQLQWPHVLGKENPFNSQIEEVFGDQGGH

The query sequence (length=526) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 5w7d:A 528 528 0.9981 0.9943 0.9943 0.0 5w7e:A, 5w7e:B, 5w7f:A, 5w7f:B
2 5w7c:C 420 417 0.6559 0.8214 0.8273 0.0 5w78:B, 5w7c:D
3 5w7b:C 413 417 0.6293 0.8015 0.7938 0.0 5w7a:B, 5w7b:D
4 5w7b:A 94 91 0.1160 0.6489 0.6703 1.86e-38 5w7b:B
5 8any:b 150 70 0.0399 0.1400 0.3000 0.43 7a5f:b3, 7a5g:b3, 7a5h:b, 7a5i:b3, 7a5j:b, 7a5k:b3, 5aj4:Bg, 6gaw:Bg, 6gb2:Bg, 6i9r:b, 3j7y:b, 3j9m:b, 8k2a:Lq, 8k2b:Lq, 7l08:b, 7l20:b, 7nqh:Bg, 7nql:Bg, 7nsh:Bg, 7nsi:Bg, 7nsj:Bg, 6nu2:b, 6nu3:b, 7o9k:b, 7o9m:b, 7odr:b, 7ods:b, 7odt:b, 7of0:b, 7of2:b, 7of3:b, 7of4:b, 7of5:b, 7of6:b, 7of7:b, 7og4:b, 7oi6:b, 7oi7:b, 7oi8:b, 7oi9:b, 7oia:b, 7oib:b, 7oic:b, 7oid:b, 7oie:b, 8oin:Bs, 8oiq:Bs, 8oir:Bs, 8oit:Bs, 5ool:b, 5oom:b, 7pd3:b, 8pk0:b, 7po4:b, 7qh6:b, 7qh7:b, 7qi4:b, 7qi5:b, 7qi6:b, 8qsj:b, 8qu5:b, 6vlz:b, 6vmi:b, 8xt0:Lq, 8xt1:Lq, 8xt2:Lq, 8xt3:Lq, 6ydp:Bg, 6ydw:Bg, 6zm5:b, 6zm6:b, 6zs9:b, 6zsa:b, 6zsb:b, 6zsc:b, 6zsd:b, 6zse:b, 6zsg:b
6 8w7y:A 474 28 0.0228 0.0253 0.4286 2.1
7 8t5e:A 130 94 0.0494 0.2000 0.2766 2.4
8 6rr3:A 257 57 0.0380 0.0778 0.3509 2.5 6rra:A
9 3a3k:B 429 74 0.0380 0.0466 0.2703 2.6 3a3k:A, 7brg:A, 7brg:B, 7brh:A, 7brh:B, 7bri:A, 7bri:B, 7brj:A, 7brj:B, 7brk:A, 7brk:B, 7brl:A, 7brl:B, 1dp4:A, 1dp4:C, 1t34:A, 1t34:B
10 5fg3:A 598 72 0.0361 0.0318 0.2639 3.0 5yt0:A
11 8ho6:A 281 59 0.0323 0.0605 0.2881 4.0 8hoa:A, 8hod:A
12 4yf4:A 163 25 0.0247 0.0798 0.5200 4.2 4yf4:B, 4yf4:C, 4yf4:D, 4yf5:A, 4yf5:C, 4yf6:A, 4yf6:C, 1ylk:A, 1ylk:B, 1ylk:C, 1ylk:D
13 8tkp:B 187 52 0.0323 0.0909 0.3269 4.3 8tkp:E, 7usw:C, 7usw:E, 7usx:C, 7usx:E, 7usy:C, 7usy:E
14 3gri:B 423 30 0.0247 0.0307 0.4333 5.4 3gri:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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