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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
SGLQPAVCLAIRVNTFLSCSQYHKMYRTVKAITGRQIFQPLHALRNAEKVLLPGYHPFEWQPPLKNVSSRTDVGIIDGLS
GLASSVDEYPVDTIAKRFRYDSALVSALMDMEEDILEGMRSQDLDDYLNGPFTVVVKESCDGMGDVSEKHGSGPAVPEKA
VRFSFTVMRITIEHGSQNVKVFEEPKPNSVLCCKPLCLMLADESDHETLTAILSPLIAEREAMKSSELTLEMGGIPRTFK
FIFRGTGYDEKLVREVEGLEASGSVYICTLCDTTRLEASQNLVFHSITRSHAENLQRYEVWRSNPYHESVEELRDRVKGV
SAKPFIETVPSIDALHCDIGNAAEFYKIFQLEIGEVYKHPNASKEERKRWQATLDKHLRKRMNLKPIMMMNGNFARKLMT
QETVDAVCELIPSEERHEALRELMDLYLKMKPVWRSSCPAKECPESLCQYSFNSQRFAELLSTKFKYRYEGKITNYFHKT
LAHVPEIIERDGSIGAWASEGNESGNKLFRRFRKMNARQSKCYEMEDVLKHHWLYTSKYLQKFMNAHNA

The query sequence (length=549) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 6oet:C 623 548 0.9927 0.8748 0.9945 0.0 6cg0:A, 6cg0:C, 6cij:A, 6cij:C, 6cik:A, 6cik:C, 6cil:A, 6cil:C, 6cim:A, 6cim:C, 3gna:A, 3gnb:A, 6oem:A, 6oem:C, 6oen:A, 6oen:C, 6oeo:A, 6oeo:C, 6oep:A, 6oep:C, 6oeq:A, 6oeq:C, 6oer:A, 6oer:C, 6oes:A, 6oes:C, 6oet:A, 6v0v:A, 4wwx:B, 4wwx:E, 6xnx:A, 6xnx:C, 6xny:A, 6xny:C, 6xnz:A, 6xnz:C, 5zdz:A, 5zdz:C, 5ze0:A, 5ze0:C, 5ze1:A, 5ze1:C, 5ze2:A, 5ze2:C
2 6dbi:C 622 549 0.7614 0.6720 0.7614 0.0 6dbi:A, 6dbj:A, 6dbj:C, 6dbl:A, 6dbl:C, 6dbo:A, 6dbo:C, 6dbq:A, 6dbq:C, 6dbr:A, 6dbr:C, 6dbt:A, 6dbt:C, 6dbu:A, 6dbu:C, 6dbv:A, 6dbv:C, 6dbw:A, 6dbw:C, 6dbx:A, 6dbx:C, 3jbw:A, 3jbw:C, 3jbx:A, 3jbx:C, 3jby:A, 3jby:C
3 6b40:A 553 556 0.3424 0.3400 0.3381 1.22e-87 6b40:E
4 6pqx:A 480 60 0.0401 0.0458 0.3667 0.026 6pqx:E, 6pr5:A, 6pr5:E
5 6pqr:A 468 60 0.0401 0.0470 0.3667 0.028 6pqn:A, 6pqn:B, 6pqr:D, 6pqu:A, 6pqu:E, 6pqy:A, 6pqy:D
6 5eul:A 746 77 0.0383 0.0282 0.2727 0.46
7 6r7b:A 454 104 0.0455 0.0551 0.2404 2.0 6r7b:B, 6r7b:C, 6r9r:B, 6r9r:A, 6r9r:C
8 1m74:A 802 74 0.0383 0.0262 0.2838 2.8 2ibm:A, 6itc:A, 3jv2:A, 3jv2:B, 1tf2:A, 7xha:A, 7xhb:A
9 8sij:A 445 41 0.0255 0.0315 0.3415 3.3 8sij:B
10 6pgv:A 152 33 0.0182 0.0658 0.3030 7.9
11 3glj:A 395 51 0.0273 0.0380 0.2941 8.1 5j1q:A, 5jc6:A, 2jew:A, 5lrg:A, 5lrg:B, 5lrg:C, 5lrj:A, 5lrj:B, 5lrj:C, 5lrk:A, 5lrk:B, 5lrk:C, 5lyd:A, 5lyf:A, 5lyi:A, 5lyl:A, 1nsa:A, 2piy:A, 2piy:B, 2piy:C, 2piz:A, 2piz:B, 2piz:C, 2pj0:A, 2pj0:B, 2pj0:C, 2pj1:A, 2pj1:B, 2pj1:C, 2pj2:A, 2pj2:B, 2pj2:C, 2pj3:A, 2pj3:B, 2pj3:C, 2pj4:A, 2pj4:B, 2pj5:A, 2pj5:B, 2pj5:C, 2pj6:A, 2pj7:A, 2pj7:B, 2pj7:C, 2pj8:A, 2pj8:B, 2pj8:C, 2pj9:A, 2pja:A, 2pja:B, 2pja:C, 2pjb:A, 2pjb:B, 2pjb:C, 2pjc:A, 2pjc:B, 2pjc:C, 4uia:A, 4uib:A, 3wab:A, 3wc5:A, 3wc6:A, 3wc7:A, 1z5r:A, 1z5r:B, 1z5r:C, 4z65:A, 5zeq:A, 1zg7:A, 1zg7:B, 1zg7:C, 1zg8:A, 1zg8:B, 1zg8:C, 1zg9:A, 1zg9:B, 1zg9:C

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218