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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
SFIKKEWRHVMPAYFTGKHDIGVTVSNKCARGRVPMDYVNNRVWELSHADMVNDLSHAYRLFSWRSIAAGSEVYTQFAGM
RLTHDKLDSIMRKYRTLINASVDAKTADGFILRLFTVGFTKKLANSHKNHTYANSHKARQVRDVMVKCLTDACESNGVEQ
LCKDFVDEKIENEIVEKCKQICQIEGVYITKVKVIKAPALSNEQVKVLKISKDAAQLSL

The query sequence (length=219) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 5xyi:B 219 219 1.0000 1.0000 1.0000 5.35e-167
2 8jiw:BB 213 200 0.3425 0.3521 0.3750 1.83e-40 8ip8:bb, 8ip9:bb, 8ipa:bb, 8ipb:bb, 8r6f:B, 4v7e:BB
3 8auv:F 216 202 0.3288 0.3333 0.3564 9.61e-37 8b2l:F1, 7qix:F, 7qiz:v
4 7mq8:NM 233 203 0.3288 0.3090 0.3547 2.68e-36 7a01:V3, 7a09:p, 5a2q:B, 5aj0:BB, 9bdl:AS01, 9bdn:AS01, 9bdp:AS01, 8bhf:C3, 9bkd:O, 9bln:O, 8btk:Aa, 7cpu:SB, 7cpv:SB, 4d5l:B, 4d61:B, 6d90:CC, 6d9j:CC, 9f1b:Aa, 9f1c:Aa, 9f1d:Aa, 6fec:i, 5flx:B, 6g18:B, 6g4s:B, 6g4w:B, 6g51:B, 6g53:B, 6g5h:B, 6g5i:B, 8g5y:SB, 8g5z:SB, 8g60:SB, 8g61:SB, 8g6j:SB, 8glp:SB, 6gz3:BB, 6gz4:BB, 6gz5:BB, 6hcf:C1, 6hcj:C2, 6hcm:C1, 6hcq:C2, 8ifd:2o, 8ife:2o, 6ip5:2o, 6ip6:2o, 6ip8:2o, 3j7p:SB, 3j7r:SB, 3jag:BB, 3jah:BB, 3jai:BB, 3jaj:SB, 3jan:SB, 8jdj:y, 8jdk:y, 8jdl:y, 8jdm:y, 7jqb:C, 7jqc:C, 5k0y:i, 8k2c:SB, 7k5i:B, 4kzx:B, 4kzy:B, 4kzz:B, 5lks:SB, 7ls1:p2, 7ls2:p2, 5lzs:BB, 5lzt:BB, 5lzu:BB, 5lzv:BB, 5lzw:BB, 5lzx:BB, 5lzy:BB, 5lzz:BB, 7mdz:BB, 7mq9:NM, 7mqa:NM, 6mtb:BB, 6mtc:BB, 6mtd:BB, 6mte:BB, 7nwg:C2, 7nwh:BB, 7nwi:BB, 7o7y:Aa, 7o7z:Aa, 7o80:Aa, 7o81:Aa, 5oa3:B, 6ole:SB, 6olf:SB, 6olg:BB, 6oli:SB, 6olz:BB, 6om0:SB, 6om7:SB, 7oya:B2, 7oyb:B2, 7oyc:B2, 7oyd:BB, 8oz0:P, 8p03:D, 8p09:D, 8p2k:Aa, 6p4g:C, 6p4h:C, 6p5i:C, 6p5j:C, 6p5k:C, 6p5n:C, 8pj1:O, 8pj2:O, 8pj3:O, 8pj4:O, 8pj5:O, 8pj6:O, 8ppk:B, 8ppl:AB, 8q7z:Aa, 8q87:Aa, 7qgg:SB, 8qoi:SB, 7qp6:O, 7qp7:O, 7qvp:SB, 7qvp:RB, 6qzp:SB, 7r4x:B, 6r5q:u, 6r6g:u, 6r6p:u, 6r7q:u, 8rg0:O, 8scb:BB, 6sgc:C1, 7syg:C, 7syh:C, 7syi:C, 7syj:C, 7syk:C, 7syl:C, 7sym:C, 7syn:C, 7syo:C, 7syp:C, 7syq:C, 7syr:C, 7sys:C, 7syt:C, 7syu:C, 7syv:C, 7syw:C, 7syx:C, 5t2c:Ap, 8t4s:B, 7toq:AS01, 7tor:AS01, 7tql:C, 7ucj:BB, 7uck:BB, 4ug0:SB, 4ujc:CB, 4ujd:CB, 4uje:BB, 4v6x:AB, 5vyc:B1, 5vyc:B2, 5vyc:B3, 5vyc:B4, 5vyc:B5, 5vyc:B6, 6w2s:C, 6w2t:C, 7wts:B, 7wtt:B, 7wtu:B, 7wtv:B, 7wtw:B, 7wtx:B, 7wtz:B, 7wu0:B, 6xa1:SB, 7xnx:SB, 7xny:SB, 8xsx:SB, 8xsy:SB, 8xsz:SB, 8xxl:SB, 8xxm:SB, 8xxn:SB, 6y0g:SB, 8y0w:SB, 8y0x:SB, 6y2l:SB, 6y57:SB, 6yal:D, 6yam:D, 6yan:D, 6ybw:O, 8yoo:SB, 8yop:SB, 6z6l:SB, 6z6m:SB, 6z6n:SB, 7zjw:SM, 7zjx:SM, 6zlw:C, 6zm7:SB, 6zme:SB, 6zmi:SB, 6zmo:SB, 6zmt:C, 6zmw:O, 6zn5:C, 6zoj:B, 6zok:B, 6zon:p, 6zp4:p, 6zuo:B, 6zv6:B, 6zvh:B, 6zvj:p, 6zvk:V3, 6zxd:B, 6zxe:B, 6zxf:B, 6zxg:B, 6zxh:B
5 7d4i:SC 242 199 0.3196 0.2893 0.3518 9.20e-36 7a1g:Q, 7ajt:DA, 7aju:DA, 7b7d:Q, 8bn3:S1, 8bqd:Q, 8bqx:Q, 8c00:Q, 8c01:Q, 8cah:Q, 8cas:Q, 8cbj:B, 8ccs:e, 8cdl:e, 8cdr:e, 8ceh:e, 8cf5:e, 8cg8:e, 8cgn:e, 8civ:e, 8cku:e, 8cmj:e, 7d5t:SC, 7d63:SC, 5dat:S1, 5dat:s1, 5dc3:S1, 5dc3:s1, 5dge:S1, 5dge:s1, 5dgf:S1, 5dgf:s1, 5dgv:S1, 5dgv:s1, 6eml:Q, 8eub:BB, 8evp:BB, 8evq:BB, 8evr:BB, 8evs:BB, 8evt:BB, 8ewb:BB, 8ewc:BB, 6fai:B, 5fci:S1, 5fci:s1, 5fcj:S1, 5fcj:s1, 6fyx:B, 6fyy:B, 6gq1:r, 6gqb:r, 6gqv:r, 6gsm:B, 6gsn:B, 6hhq:s1, 6hhq:C, 5i4l:S1, 5i4l:s1, 6i7o:Q, 6i7o:Qb, 8i7j:B, 5it7:B, 5it9:B, 3j6x:S1, 3j6y:S1, 3j77:S1, 3j78:S1, 3j80:B, 3j81:B, 3jam:B, 3jap:B, 5juo:YA, 5jup:YA, 5jus:YA, 5jut:YA, 5juu:YA, 8k2d:SB, 8k82:SB, 6ke6:SC, 5ll6:Q, 6lqp:SC, 6lqq:SC, 6lqr:SC, 6lqs:SC, 6lqt:SC, 5lyb:S1, 5lyb:s1, 5m1j:B2, 5mc6:Q, 5mei:s1, 5mei:C, 7mpi:BB, 7mpj:BB, 7n8b:BB, 5ndg:S1, 5ndg:s1, 5ndv:S1, 5ndv:s1, 5ndw:S1, 5ndw:s1, 7nrc:SQ, 7nrd:SQ, 5obm:S1, 5obm:s1, 5on6:s1, 5on6:C, 7osa:eS1, 7osm:eS1, 6q8y:Q, 6rbd:B, 6rbe:B, 7rr5:SB, 8rw1:B, 6s47:BC, 8s8d:B, 8s8e:B, 8s8f:B, 8s8g:B, 8s8h:B, 8s8i:B, 8s8j:B, 6snt:B, 6sv4:Q, 6sv4:Qb, 6sv4:Qc, 6t4q:SB, 6t7i:SB, 6t7t:SB, 6t83:Ba, 6t83:c, 5tbw:s1, 5tbw:C, 6tb3:Q, 5tga:S1, 5tga:s1, 5tgm:S1, 5tgm:s1, 6tnu:Q, 4u3m:S1, 4u3m:s1, 4u3n:S1, 4u3n:s1, 4u3u:S1, 4u3u:s1, 4u4n:S1, 4u4n:s1, 4u4o:S1, 4u4o:s1, 4u4q:S1, 4u4q:s1, 4u4r:S1, 4u4r:s1, 4u4u:S1, 4u4u:s1, 4u4y:S1, 4u4y:s1, 4u4z:S1, 4u4z:s1, 4u50:S1, 4u50:s1, 4u51:S1, 4u51:s1, 4u52:S1, 4u52:s1, 4u53:S1, 4u53:s1, 4u55:S1, 4u55:s1, 4u56:S1, 4u56:s1, 4u6f:S1, 4u6f:s1, 4uer:4, 6uz7:B, 4v88:AB, 4v88:CB, 4v8y:AB, 4v8z:AB, 4v92:BB, 6woo:BB, 7wtl:SB, 7wtm:SB, 7wtn:SB, 7wto:SB, 7wtp:SB, 7wtq:SB, 7wtr:SB, 5wyj:SC, 5wyk:SC, 6xiq:r, 6xir:r, 8y0u:SB, 6y7c:B, 6z6j:SB, 6z6k:SB, 6zce:C, 7zpq:AB, 6zqa:DA, 6zqb:DA, 6zqc:DA, 6zqd:DA, 6zqe:DA, 6zqf:DA, 6zqg:DA, 7zrs:AB, 6zu9:Q, 7zuw:AB, 7zux:DB, 6zvi:j, 7zw0:sQ
6 4v6w:AB 220 201 0.3196 0.3182 0.3483 2.14e-35 6xu6:AB, 6xu7:AB, 6xu8:AB
7 7olc:SB 232 200 0.3196 0.3017 0.3500 4.63e-33 7old:SB, 8oo0:SB, 5oql:l, 7r81:C2, 6rxt:Ca, 6rxu:Ca, 6rxv:Ca, 6rxx:Ca, 7z3n:SB, 7z3o:SB
8 8c3a:D 214 200 0.3014 0.3084 0.3300 1.21e-32 8c3a:CO, 8cq7:D, 8cq7:CO, 8cqw:D, 8cqw:CO, 8cre:D, 8cre:CO, 8oeq:D, 8oeq:CO, 7pzy:C, 7q08:C, 7q0f:C, 7q0p:C, 7q0r:C, 8q5i:C
9 3j7a:B 210 200 0.3059 0.3190 0.3350 1.79e-32 3jbn:B, 3jbo:B, 3jbp:B, 6okk:B, 8tpu:SB
10 9bh5:AB 210 200 0.2785 0.2905 0.3050 3.16e-32 9cai:AB
11 5xxu:B 212 199 0.2922 0.3019 0.3216 5.59e-31
12 6zj3:SA 221 204 0.3196 0.3167 0.3431 2.95e-30
13 4bts:B4 221 215 0.3059 0.3032 0.3116 3.54e-28 4bts:A4, 4bts:C4, 4bts:D4, 5jpq:o, 4v5o:A4, 4v5o:B4
14 8ova:A0 220 202 0.2922 0.2909 0.3168 1.23e-24 8ove:A0, 4v8m:A0
15 8rxh:SA 244 203 0.2785 0.2500 0.3005 1.95e-24 8a3w:SA, 8a98:SA, 6az1:A, 8ovj:SA, 8rxx:SA, 5t2a:0
16 7ase:W 217 199 0.2740 0.2765 0.3015 2.41e-24 5opt:W
17 8br8:SD 231 212 0.2603 0.2468 0.2689 4.64e-22 8brm:SD, 8bsi:SD, 8bsj:SD, 8btd:SD, 8btr:SD, 8fvy:B, 8g4s:B, 7pwf:B, 7pwo:B1
18 6rm3:SB0 210 197 0.2511 0.2619 0.2792 8.44e-20
19 6zu5:SB0 196 201 0.2785 0.3112 0.3035 2.05e-18
20 7qep:S1 209 200 0.2557 0.2679 0.2800 3.23e-18
21 8p5d:SB0 204 195 0.2557 0.2745 0.2872 3.84e-18 8p60:SB0, 8p60:RB0, 7qca:SB0
22 5jb3:A 190 195 0.2100 0.2421 0.2359 1.66e-13 5jbh:A, 6sw9:A, 6swc:A, 6swd:A, 4v4n:BA, 4v6u:AA, 7zag:A, 7zah:A, 7zai:A, 7zhg:A
23 8hkx:S3AE 189 179 0.2192 0.2540 0.2682 1.80e-12 8hky:S3AE, 8hkz:S3AE, 8hl1:S3AE, 8hl2:S3AE, 8hl3:S3AE, 8hl4:S3AE, 8hl5:S3AE, 8wkp:S3AE, 8wq2:S3AE, 8wq4:S3AE
24 6tmf:D 184 195 0.2055 0.2446 0.2308 5.07e-10
25 6skf:Ad 190 195 0.1963 0.2263 0.2205 1.82e-09 6skg:Ad, 6th6:Ad
26 8e23:D 603 85 0.0959 0.0348 0.2471 1.3
27 6b9e:B 387 60 0.0776 0.0439 0.2833 3.7 6b9d:A, 6b9d:B, 3q5e:E, 3q5e:G
28 5kkw:A 237 34 0.0411 0.0380 0.2647 5.2
29 7f5s:LB 402 110 0.1233 0.0672 0.2455 7.1 7a01:52, 8a3d:E, 5aj0:AB, 8b5l:B, 8b6c:B, 9bdl:AL03, 9bdn:AL03, 9bdp:AL03, 7bhp:LB, 8bhf:k3, 8bpo:B2, 8btk:BB, 7cpu:LB, 7cpv:LB, 4d5y:B, 4d67:B, 6d90:B, 6d9j:B, 9f1b:BB, 9f1c:BB, 9f1d:BB, 8fkp:LN, 8fkq:LN, 8fkr:LN, 8fks:LN, 8fl2:LN, 8fl3:LN, 8fl4:LN, 8fl6:LN, 8fl7:LN, 8fl9:LN, 8fla:LN, 8flb:LN, 8flc:LN, 8fld:LN, 8fle:LN, 8flf:LN, 6frk:B, 6ftg:B, 6fti:B, 6ftj:B, 8g5y:LB, 8g5z:LB, 8g60:LB, 8g61:LB, 8g6j:LB, 8glp:LB, 6gz3:AB, 6gz4:AB, 6gz5:AB, 6hcf:B3, 6hcj:B3, 6hcm:B3, 6hcq:B3, 8idt:B, 8idy:B, 8ie3:B, 8ifd:1E, 8ife:1E, 8ine:B, 8inf:B, 8ink:B, 6ip5:1E, 6ip6:1E, 6ip8:1E, 8ipd:B, 8ipx:B, 8ipy:B, 8ir1:B, 8ir3:B, 3j7o:B, 3j7p:B, 3j7q:B, 3j7r:B, 3j92:B, 3jag:B, 3jah:B, 3jai:B, 3jaj:B, 3jan:B, 8jdj:H, 8jdk:H, 8jdl:H, 8jdm:H, 8k2c:LB, 5lks:LB, 6lqm:B, 6lsr:B, 6lss:B, 7ls1:E2, 7ls2:E2, 6lu8:B, 5lzs:B, 5lzt:B, 5lzu:B, 5lzv:B, 5lzw:B, 5lzx:B, 5lzy:B, 5lzz:B, 7mdz:B, 6mtb:B, 6mtc:B, 6mtd:B, 6mte:B, 7nfx:B, 7nwg:B3, 7nwh:B, 7nwi:B, 7o7y:BB, 7o7z:BB, 7o80:BB, 7o81:BB, 7obr:B, 8ohd:LB, 8oj0:LB, 8oj5:LB, 8oj8:LB, 6ole:B, 6olf:B, 6olg:AB, 6oli:B, 6olz:AB, 6om0:B, 6om7:B, 7ow7:E, 7oya:B1, 7oyb:B1, 7oyc:B1, 7oyd:B, 8p2k:BB, 6p5i:AB, 6p5j:AB, 6p5k:AB, 6p5n:AB, 8q7z:BB, 8q87:BB, 8qfd:B, 7qgg:B, 8qoi:LB, 7qvp:LB, 7qvp:MB, 7qwq:B, 7qwr:B, 7qws:B, 6qzp:LB, 6r5q:B, 6r6g:B, 6r6p:B, 6r7q:B, 8rjb:w, 8rjc:w, 8rjd:w, 8scb:B, 6sgc:B2, 6swa:B, 5t2c:E, 6t59:B3, 7tm3:w, 7toq:AL03, 7tor:AL03, 7tut:w, 7ucj:B, 7uck:B, 4ug0:LB, 4ujc:BB, 4ujd:AB, 4uje:CB, 4v5z:Bb, 4v6x:CB, 6w6l:B, 6xa1:LB, 7xnx:LB, 7xny:LB, 8xsx:LB, 8xsy:LB, 8xsz:LB, 6y0g:LB, 8y0w:LB, 8y0x:LB, 6y2l:LB, 6y57:LB, 6y6x:LB, 8yoo:LB, 8yop:LB, 6z6l:LB, 6z6m:LB, 6z6n:LB, 7zjw:LE, 7zjx:LE, 6zm7:LB, 6zme:LB, 6zmi:LB, 6zmo:LB, 6zvk:52
30 4okd:A 801 64 0.0913 0.0250 0.3125 8.2 4okd:B
31 8fkt:LN 358 58 0.0822 0.0503 0.3103 8.4 8fku:LN, 8fkv:LN, 8fkw:LN, 8fkx:LN, 8fky:LN, 8fkz:LN, 8fl0:LN
32 5gan:B 1781 105 0.1187 0.0146 0.2476 8.9 4bgd:A, 5gao:B, 5gap:B, 5nrl:B, 5zwm:D, 5zwo:D
33 5w1a:A 786 43 0.0639 0.0178 0.3256 9.5 8exw:A, 5w1a:C

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218