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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
SETLFEKNMFVLLNRGRFAGNKGIIVDTDLENNRIIIAGVSKIPKNKKRKTIVFLKKMNPMHIMATTYKRDIGLSLDNLD
SIFEDKVKKAVALNRVREIFNKNKNNEGFAWLYKKLEI

The query sequence (length=118) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 8p5d:LZ0 118 118 1.0000 1.0000 1.0000 1.06e-81 8p60:LZ0, 8p60:KZ0, 7qca:LZ0
2 6zu5:LZ0 127 125 0.3729 0.3465 0.3520 3.59e-18
3 6rm3:LZ0 125 125 0.3983 0.3760 0.3760 1.09e-15
4 7qep:N7 118 98 0.2712 0.2712 0.3265 3.51e-10
5 8ip8:CA 136 131 0.3390 0.2941 0.3053 1.69e-07 8ipa:CA, 8ipb:CA, 8jiv:CZ, 4v3p:La, 4v7e:CZ
6 8rxh:LY 133 124 0.2712 0.2406 0.2581 2.09e-07 8a3w:Y, 8a98:Y, 6az3:Y, 3jcs:Y, 8ovj:Y, 8rxx:LY, 5t2a:Y
7 8azw:M 134 135 0.3390 0.2985 0.2963 2.17e-07 8b2l:M3, 7qiw:b, 7qiz:b
8 8esq:Z 134 128 0.2966 0.2612 0.2734 3.44e-07 8esr:Z, 8etc:Z, 8eug:Z, 8eui:Z
9 8ova:Ba 132 125 0.2797 0.2500 0.2640 3.44e-07 8ove:Ba, 4v8m:Ba
10 6zj3:Ln 133 124 0.2712 0.2406 0.2581 7.26e-07
11 5xy3:Z 135 134 0.2797 0.2444 0.2463 3.41e-06
12 4v8p:AN 143 95 0.2627 0.2168 0.3263 2.88e-05 4v8p:DN, 4v8p:FN, 4v8p:HN
13 8br8:La 119 69 0.1695 0.1681 0.2899 4.84e-05
14 9bh5:CZ 135 124 0.2797 0.2444 0.2661 7.22e-05 9cai:CZ
15 4d5y:Z 136 126 0.2881 0.2500 0.2698 9.44e-05 7a01:22, 8a3d:T, 5aj0:AZ, 8b5l:Z, 8b6c:Z, 9bdl:AL27, 9bdn:AL27, 9bdp:AL27, 7bhp:LZ, 8bhf:M1, 8bpo:Y2, 8btk:BZ, 7cpu:LZ, 7cpv:LZ, 4d67:Z, 6d90:Z, 6d9j:Z, 9f1b:BZ, 9f1c:BZ, 9f1d:BZ, 7f5s:LZ, 8fky:LJ, 8fkz:LJ, 8fl2:LJ, 8fl3:LJ, 8fl4:LJ, 8fl6:LJ, 8fl7:LJ, 8fl9:LJ, 8fla:LJ, 8flb:LJ, 8flc:LJ, 8fld:LJ, 8fle:LJ, 8flf:LJ, 6frk:Z, 6ftg:Z, 6fti:Z, 6ftj:Z, 8g5y:LZ, 8g5z:LZ, 8g60:LZ, 8g61:LZ, 8g6j:LZ, 8glp:LZ, 6gz3:AZ, 6gz4:AZ, 6gz5:AZ, 6hcf:Z3, 6hcj:Z3, 6hcm:Z3, 6hcq:Z3, 8idt:i, 8idy:i, 8ie3:i, 8ifd:2T, 8ife:2T, 8ine:i, 8inf:i, 8ink:i, 6ip5:2T, 6ip6:2T, 6ip8:2T, 8ipd:i, 8ipx:i, 8ipy:i, 8ir1:i, 8ir3:i, 3j7o:Z, 3j7p:Z, 3j7q:Z, 3j7r:Z, 3j92:Z, 3jag:Z, 3jah:Z, 3jai:Z, 3jaj:Z, 3jan:Z, 8jdj:e, 8jdk:e, 8jdl:e, 8jdm:e, 8k2c:LZ, 5lks:LZ, 6lqm:i, 6lsr:i, 6lss:i, 7ls1:T2, 7ls2:T2, 6lu8:i, 5lzs:Z, 5lzt:Z, 5lzu:Z, 5lzv:Z, 5lzw:Z, 5lzx:Z, 5lzy:Z, 5lzz:Z, 7mdz:Z, 6mtb:Z, 6mtc:Z, 6mtd:Z, 6mte:Z, 7nfx:Z, 7nwg:Z3, 7nwh:Z, 7nwi:Z, 7o7y:BZ, 7o7z:BZ, 7o80:BZ, 7o81:BZ, 7obr:Z, 8ohd:LZ, 8oj0:LZ, 8oj5:LZ, 8oj8:LZ, 6ole:a, 6olf:a, 6olg:AZ, 6oli:a, 6olz:AZ, 6om0:a, 6om7:a, 7ow7:T, 7oya:Z1, 7oyb:Z1, 7oyc:Z1, 7oyd:Z, 8p2k:BZ, 6p5i:AZ, 6p5j:AZ, 6p5k:AZ, 6p5n:AZ, 8q7z:BZ, 8q87:BZ, 8qfd:Z, 7qgg:a, 8qoi:LZ, 7qvp:LZ, 7qvp:MZ, 7qwq:Z, 7qwr:Z, 7qws:Z, 6qzp:LZ, 6r5q:Z, 6r6g:Z, 6r6p:Z, 6r7q:Z, 8rjb:Z, 8rjc:Z, 8rjd:Z, 8scb:Z, 6sgc:Z2, 6swa:X, 5t2c:T, 6t59:Z3, 7tm3:Z, 7toq:AL27, 7tor:AL27, 7tut:Z, 7ucj:Z, 7uck:Z, 4ug0:LZ, 4ujc:BZ, 4ujd:AZ, 4uje:CZ, 4v6x:CZ, 6w6l:a, 6xa1:LZ, 7xnx:LZ, 7xny:LZ, 8xsx:LZ, 8xsy:LZ, 8xsz:LZ, 6y0g:LZ, 8y0w:LZ, 8y0x:LZ, 6y2l:LZ, 6y57:LZ, 6y6x:LZ, 8yoo:LZ, 8yop:LZ, 6z6l:LZ, 6z6m:LZ, 6z6n:LZ, 7zjw:Lc, 7zjx:Lc, 6zm7:LZ, 6zme:LZ, 6zmi:LZ, 6zmo:LZ, 6zvk:22
16 5t5h:a 105 68 0.1949 0.2190 0.3382 3.11e-04
17 8fru:Z 134 83 0.1780 0.1567 0.2530 6.42e-04 8brm:La, 8bsi:La, 8bsj:La, 8btd:La, 8btr:La, 7pwg:Z, 7pwo:Z2
18 8i9x:LZ 135 128 0.2627 0.2296 0.2422 0.001 8i9y:LZ, 8i9z:LZ, 8ia0:LZ, 7olc:LZ, 7old:LZ, 8oo0:LZ, 8pv1:LZ, 8pv2:LZ, 8pv3:LZ, 8pv4:LZ, 8pv5:LZ, 8pv6:LZ, 8pv7:LZ, 8pv8:LZ, 8pvk:LZ, 8pvl:LZ, 7z3n:LZ, 7z3o:LZ
19 4v6w:CZ 134 134 0.2966 0.2612 0.2612 0.002 6xu6:CZ, 6xu7:CZ, 6xu8:CZ
20 7r81:b1 135 124 0.2373 0.2074 0.2258 0.002
21 8c3a:AA 135 125 0.2542 0.2222 0.2400 0.003 8c3a:BU, 8cq7:AA, 8cq7:BU, 8cqw:AA, 8cqw:BU, 8cre:AA, 8cre:BU, 8oeq:AA, 8oeq:BU, 7pzy:AA, 7q08:AA, 7q0f:AA, 7q0p:AA, 7q0r:AA, 8q5i:AA
22 8aaf:M 135 120 0.2627 0.2296 0.2583 0.003 8agt:M, 8agu:M, 8agv:M, 8agw:M, 8agx:M, 8agz:M, 5apn:Z, 5apo:Z, 7azy:O, 7b7d:LV, 8bip:LZ, 8bjq:LZ, 8bn3:N7, 8bqd:AN, 8bqx:AN, 7bt6:Z, 7btb:Z, 6cb1:Z, 8ccs:L, 8cdl:L, 8cdr:L, 8ceh:L, 8cf5:L, 8cg8:L, 8cgn:L, 8civ:L, 8cku:L, 8cmj:L, 5dat:N7, 5dat:n7, 5dc3:N7, 5dc3:n7, 5dge:N7, 5dge:n7, 5dgf:N7, 5dgf:n7, 5dgv:N7, 5dgv:n7, 6elz:Z, 8eub:AZ, 8evp:AZ, 8evq:AZ, 8evr:AZ, 8evs:AZ, 8evt:AZ, 8ewb:AZ, 8ewc:AZ, 5fci:N7, 5fci:n7, 5fcj:N7, 5fcj:n7, 6ft6:Z, 5gak:b, 6gq1:Z, 6gqb:Z, 6gqv:Z, 5h4p:Z, 6hd7:b, 8hfr:Zq, 6hhq:AA, 6hhq:DB, 5i4l:N7, 5i4l:n7, 6i7o:AN, 6i7o:XN, 5it7:ZZ, 3j6x:67, 3j6y:67, 3j77:77, 3j78:77, 3jct:Z, 5jcs:Z, 5juo:EA, 5jup:EA, 5jus:EA, 5jut:EA, 5juu:EA, 8k2d:LZ, 8k82:LZ, 5lyb:N7, 5lyb:n7, 5m1j:Z5, 6m62:Z, 5mc6:AN, 5mei:AA, 5mei:DB, 7mpi:AZ, 7mpj:AZ, 6n8j:Z, 6n8k:Z, 6n8l:Z, 6n8m:m, 6n8n:m, 6n8o:m, 7n8b:AZ, 7nac:Z, 7nad:Z, 5ndg:N7, 5ndg:n7, 5ndv:N7, 5ndv:n7, 5ndw:N7, 5ndw:n7, 7nrc:Lb, 7nrd:Lb, 5obm:N7, 5obm:n7, 7of1:Z, 7oh3:Z, 7ohq:Z, 7ohr:Z, 7ohv:Z, 6oig:Z, 5on6:AA, 5on6:DB, 7osa:eL27, 7osm:eL27, 8p8m:QZ, 8p8n:QZ, 8p8u:QZ, 8pfr:QZ, 6q8y:AN, 6qik:Y, 6qt0:Y, 6qtz:Y, 7r72:Z, 7r7a:Z, 6r84:b, 6r86:b, 6r87:b, 6ri5:Y, 7rr5:LZ, 6rzz:Y, 6s05:Y, 6s47:Ab, 6snt:aq, 6sv4:AN, 6sv4:XN, 6sv4:zN, 6t4q:LZ, 5t62:m, 5t6r:m, 6t7i:LZ, 6t7t:LZ, 6t83:Zy, 6t83:K, 5tbw:AA, 5tbw:DB, 6tb3:AN, 5tga:N7, 5tga:n7, 5tgm:N7, 5tgm:n7, 6tnu:AN, 7too:AL27, 7top:AL27, 7u0h:Z, 4u3m:N7, 4u3m:n7, 4u3n:N7, 4u3n:n7, 4u3u:N7, 4u3u:n7, 4u4n:N7, 4u4n:n7, 4u4o:N7, 4u4o:n7, 4u4q:N7, 4u4q:n7, 4u4r:N7, 4u4r:n7, 4u4u:N7, 4u4u:n7, 4u4y:N7, 4u4y:n7, 4u4z:N7, 4u4z:n7, 4u50:N7, 4u50:n7, 4u51:N7, 4u51:n7, 4u52:N7, 4u52:n7, 4u53:N7, 4u53:n7, 4u55:N7, 4u55:n7, 4u56:N7, 4u56:n7, 4u6f:N7, 4u6f:n7, 7ug6:Z, 7uoo:Z, 7uqb:Z, 7uqz:Z, 6uz7:AZ, 7v08:Z, 4v6i:Ba, 4v7f:Y, 4v88:BZ, 4v88:DZ, 4v8t:Z, 4v8y:BZ, 4v8z:BZ, 8v87:Z, 4v91:Z, 6woo:Z, 6xiq:Z, 6xir:Z, 8y0u:LZ, 6ylg:Z, 6ylh:Z, 6ylx:Z, 6yly:Z, 7z34:Z, 6z6j:LZ, 6z6k:LZ, 7zpq:BY, 7zrs:BY, 7zs5:Ba, 7zuw:BY, 7zux:EY, 7zw0:Lc
23 5xxb:Y 144 74 0.2203 0.1806 0.3514 0.029
24 3j79:1 140 78 0.2203 0.1857 0.3333 0.046 3jbn:A1, 3jbo:A1, 3jbp:A1, 8tpu:A1, 5umd:1
25 8hku:L141 86 68 0.1780 0.2442 0.3088 0.25 8hku:L142, 8hkv:L141, 8hkv:L142, 8hky:L141, 8hky:L142, 8hkz:L141, 8hkz:L142, 8hl1:L141, 8hl1:L142, 8hl2:L141, 8hl2:L142, 8hl3:L141, 8hl3:L142, 8hl4:L141, 8hl4:L142, 8hl5:L141, 8hl5:L142
26 4pof:A 255 43 0.1186 0.0549 0.3256 0.30 5iy0:A, 5iy0:B, 5iy0:C, 5iy0:D, 5iy0:E, 5iy0:F, 4pof:B, 4pof:C, 4pof:D, 4pof:E, 4pof:F, 4pog:A, 4pog:E, 4pog:F, 4pog:K, 4pog:L, 4pog:G, 4pog:H, 4pog:I, 4pog:J, 4pog:B, 4pog:C, 4pog:D, 4ywl:A, 4ywl:B, 4ywl:C, 4ywl:D, 4ywl:E, 4ywl:F, 4ywl:G, 4ywl:H, 4ywl:I, 4ywl:J, 4ywm:A, 4ywm:B, 4ywm:C, 4ywm:D, 4ywm:E, 4ywm:F, 4ywm:G, 4ywm:H, 4ywm:I, 4ywm:J
27 5ms0:F 181 36 0.1102 0.0718 0.3611 0.30 6c6u:N, 8e3f:F, 8e5k:F, 8e5o:F, 8e6x:F, 8e6z:F, 8g31:u, 8g34:u, 6gov:G, 7py0:G, 7py1:G, 7py5:G, 7py8:G, 6tqn:G, 6tqo:G, 6vu3:AB, 6vyq:AB, 6vyr:AB, 6vys:AB, 6vyt:AB, 6vyu:AB, 6vyw:AB, 6vyx:AB, 6vyy:AB, 6vyz:AB, 6vz2:AB, 6vz3:AB, 6vz5:AB, 6vz7:AB, 6x6t:AB, 6x7f:AB, 6x7k:AB, 6x9q:AB, 6xdq:AB, 6xdr:AB, 6xgf:AB, 6xii:AB, 6xij:AB, 6z9p:G, 6z9q:G, 6z9r:G, 6ztj:CF, 6ztl:CF, 6ztn:CF
28 6skf:BX 120 50 0.1356 0.1333 0.3200 0.98 6skg:BX, 6th6:BX
29 4yhx:A 294 91 0.2203 0.0884 0.2857 4.2
30 8t4m:D 533 46 0.1271 0.0281 0.3261 4.8 9bc6:D, 9bc6:A, 9bc6:B, 9bc6:C, 9bc7:A, 9bc7:B, 9bc7:C, 9bc7:D, 3bpz:A, 3bpz:B, 3bpz:C, 3bpz:D, 5khg:A, 5khh:A, 5khi:A, 5khj:A, 5khj:B, 5khk:A, 2q0a:A, 2q0a:B, 1q3e:A, 1q3e:B, 1q43:A, 1q43:B, 1q5o:A, 8t4m:C, 8t4m:B, 8t4m:A, 8t4y:A, 8t4y:D, 8t4y:C, 8t4y:B, 3u0z:A, 3u0z:B, 3u10:A, 5u6p:A, 5u6p:B, 5u6p:C, 5u6p:D, 8uc7:D, 8uc7:A, 8uc7:B, 8uc7:C, 6uqf:A, 6uqf:B, 6uqf:C, 6uqf:D, 6uqg:A, 6uqg:B, 6uqg:C, 6uqg:D
31 3k2d:A 237 92 0.2288 0.1139 0.2935 5.2 3k2d:B
32 8t50:C 474 46 0.1271 0.0316 0.3261 5.3 8t50:B, 8t50:A, 8t50:D
33 2o2z:A 310 47 0.1610 0.0613 0.4043 6.6 2o2z:B, 2o2z:C, 2o2z:D
34 7qbz:A 638 77 0.1949 0.0361 0.2987 7.1 7qc0:A
35 4v8m:Bv 157 57 0.1186 0.0892 0.2456 9.8 8ova:Bv, 8ove:Bv

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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