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TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
SERIPPQSIEAEQAVLGAVFLDPAALVPASEILIPEDFYRAAHQKIFHAMLRVADRGEPVDLVTVTAELAASEQLEEIGG
VSYLSELADAVPTAANVEYYARIVEEKSVLRRLIRTATSIAQDGYTREDEIDVLLDEADRKIMEVSQRKHSGAFKNIKDI
LVQTYDNIEMLHNGEITGIPTGFTELDRMTSGFQRSDLIIVAARPSVGKTAFALNIAQNVATKTNENVAIFSLEMSAQQL
VMRMLCAEGNINAQNLRTGKLTPEDWGKLTMAMGSLSNAGIYIDDTPSIRVSDIRAKCRRLKQESGLGMIVIDYLQLIQG
SGRSKENRQQEVSEISRSLKALARELEVPVIALSQLSRRPMMSDIRESGSIEQDADIVAFLYRDDYYNKDSENKNIIEII
IAKQRNGPVGTVQLAFIKEYNKFVNLERRF

The query sequence (length=430) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 4esv:C 434 434 0.9860 0.9770 0.9770 0.0 4esv:A, 4esv:B, 4esv:D, 4esv:E, 4esv:F, 4esv:G, 4esv:H, 4esv:I, 4esv:J, 4esv:K, 4esv:L, 2vye:A, 2vye:B
2 8a3v:A 450 439 0.4605 0.4400 0.4510 9.12e-129 8a3v:B, 6t66:A, 6t66:B, 6t66:C, 6t66:D, 6t66:E, 6t66:F
3 6bbm:D 455 445 0.4721 0.4462 0.4562 3.70e-128 6bbm:F, 6bbm:B, 6bbm:C, 6bbm:E, 6qel:A, 6qel:B, 6qel:C, 6qel:D, 6qel:E, 6qel:F, 6qem:A, 6qem:B, 6qem:C, 6qem:D, 6qem:E, 6qem:F, 7t20:B, 7t20:C, 7t20:E, 7t20:F, 7t20:D, 7t21:A, 7t21:B, 7t21:C, 7t21:D, 7t21:E, 7t21:F, 7t22:A, 7t22:B, 7t22:C, 7t22:D, 7t22:E, 7t22:F, 7t23:A, 7t23:B, 7t23:C, 7t23:D, 7t23:E, 7t23:F
4 6bbm:A 405 436 0.4419 0.4691 0.4358 2.27e-119
5 4nmn:A 425 433 0.4000 0.4047 0.3972 1.06e-101 4nmn:B
6 4zc0:B 434 444 0.3512 0.3479 0.3401 3.93e-71 3gxv:A
7 6n9x:B 500 352 0.1860 0.1600 0.2273 1.10e-05 1e0j:A, 1e0j:B, 1e0j:C, 1e0j:D, 1e0j:E, 1e0j:F, 6n7i:A, 6n7i:B, 6n7i:C, 6n7i:D, 6n7i:E, 6n7n:A, 6n7n:B, 6n7n:C, 6n7n:D, 6n7n:E, 6n7n:F, 6n7s:A, 6n7s:B, 6n7s:C, 6n7s:D, 6n7s:E, 6n7t:A, 6n7t:B, 6n7t:C, 6n7t:D, 6n7t:E, 6n7t:F, 6n7v:A, 6n7v:B, 6n7v:C, 6n7v:D, 6n7v:E, 6n7v:F, 6n9u:E, 6n9v:A, 6n9v:B, 6n9v:C, 6n9v:D, 6n9v:E, 6n9v:F, 6n9w:A, 6n9w:B, 6n9w:C, 6n9w:D, 6n9w:E, 6n9x:A, 6n9x:C, 6n9x:D, 6n9x:E
8 8dtp:B 432 215 0.1116 0.1111 0.2233 0.032 8dtp:C, 8dtp:D, 8dtp:E, 8dtp:F, 8dtp:A, 8due:B, 8due:C, 8due:D, 8due:E, 8due:F, 8due:A, 8duo:A, 8duo:B, 8duo:C, 8duo:D, 8duo:E, 8duo:F, 8dvf:B, 8dvf:C, 8dvf:D, 8dvf:E, 8dvf:F, 8dvf:A, 8dvi:B, 8dvi:C, 8dvi:D, 8dvi:E, 8dvi:F, 8dvi:A, 8dw6:B, 8dw6:C, 8dw6:D, 8dw6:E, 8dw6:F, 8dw6:A, 8g0z:B, 8g0z:C, 8g0z:D, 8g0z:E, 8g0z:F, 8g0z:A, 8gao:B, 8gao:C, 8gao:D, 8gao:E, 8gao:F, 8gao:A
9 1cr1:A 245 246 0.1140 0.2000 0.1992 0.038 1cr2:A, 1cr4:A
10 8oo7:E 443 42 0.0442 0.0429 0.4524 0.17 8av6:E, 8av6:D, 8av6:F, 6fhs:E, 6fhs:D, 6fhs:F, 6fml:E, 6fml:D, 6fml:F, 8oo7:D, 8oo7:F, 8ooc:D, 8ooc:E, 8ooc:F, 8oop:D, 8oop:E, 8oop:F, 8oor:D, 8oor:E, 8oor:F, 4ww4:B
11 5fm7:B 422 42 0.0442 0.0450 0.4524 0.17
12 7v3x:V 437 195 0.1047 0.1030 0.2308 1.2 7v3x:U
13 6gej:Y 447 42 0.0372 0.0358 0.3810 1.4 8ets:W, 8ets:U, 8ets:Y, 8etu:W, 8etu:U, 8etu:Y, 8etw:W, 8etw:U, 8etw:Y, 8eu9:W, 8eu9:U, 8eu9:Y, 8euf:W, 8euf:U, 8euf:Y, 6gej:U, 6gej:W, 6gen:U, 6gen:W, 6gen:Y
14 8gbj:D 308 51 0.0372 0.0519 0.3137 1.5 8faz:D, 8ouy:C, 8ouz:C
15 5l7j:A 406 59 0.0395 0.0419 0.2881 1.8 6ia6:A, 5l7l:A
16 4o0m:A 494 80 0.0488 0.0425 0.2625 3.0 5jwo:A, 4o0m:B, 4o0m:C
17 5lz6:A 126 31 0.0326 0.1111 0.4516 3.2 6q67:A, 6q68:A
18 7zi4:C 447 25 0.0279 0.0268 0.4800 3.8 9c57:E, 9c57:C, 9c57:A, 9c62:C, 9c62:E, 9c62:A, 6hts:A, 6hts:C, 6hts:E, 5oaf:A, 5oaf:C, 5oaf:E, 8x15:M, 8x15:O, 8x15:Q, 8x19:M, 8x19:O, 8x19:Q, 8x1c:M, 8x1c:O, 8x1c:Q, 8xvg:A, 8xvg:C, 8xvg:E, 8xvt:A, 8xvt:C, 8xvt:E, 7zi4:A, 7zi4:E
19 9ema:A 326 25 0.0279 0.0368 0.4800 3.9 7aho:A, 7aho:C, 2c9o:C, 9ema:B, 9ema:C, 9emc:A, 9emc:B, 9emc:C, 6fo1:A, 6fo1:B, 6fo1:C, 6k0r:A, 6k0r:B, 6k0r:C, 6k0r:G, 6k0r:H, 6k0r:I, 7p6x:A, 7p6x:B, 7p6x:C, 6qi8:C, 6qi9:C, 2xsz:A, 2xsz:B, 2xsz:C
20 7ole:C 427 25 0.0279 0.0281 0.4800 3.9 7ole:E
21 7dy1:D 458 80 0.0488 0.0459 0.2625 3.9 7dy1:A, 7dy1:B, 7dy1:C, 7dy1:E, 7dy1:F
22 2c9o:A 398 25 0.0279 0.0302 0.4800 4.2 2c9o:B
23 6qi8:A 317 75 0.0488 0.0662 0.2800 4.2 7aho:B, 6qi8:B, 6qi9:A, 6qi9:B
24 8ets:V 443 25 0.0302 0.0293 0.5200 4.2 8ets:X, 8ets:T, 8etu:V, 8etu:X, 8etu:T, 8etw:V, 8etw:X, 8etw:T, 8eu9:V, 8eu9:X, 8eu9:T, 8euf:V, 8euf:X, 8euf:T, 6gej:T, 6gej:V, 6gej:X, 6gen:T, 6gen:V, 6gen:X
25 3add:A 251 89 0.0488 0.0837 0.2360 5.5 3a4l:A, 3a4l:B, 3a4m:A, 3a4m:B, 3adb:A, 3adb:B, 3adc:A, 3adc:B, 3add:B, 3am1:A
26 7zvo:A 131 43 0.0256 0.0840 0.2558 6.0
27 5olw:A 224 42 0.0349 0.0670 0.3571 6.5 4c4r:A, 4c4s:A, 4c4t:A, 3fm9:A, 6h8u:A, 6h8v:A, 6h8v:B, 6h8w:A, 6h8x:A, 6h8x:B, 6h8y:A, 6h8z:A, 6h90:A, 6h91:A, 6h91:B, 6h92:A, 6h92:B, 6h93:A, 6h93:B, 6h94:A, 6hdg:A, 6hdh:A, 6hdh:B, 6hdi:A, 6hdi:B, 6hdj:A, 6hdk:A, 6hdl:A, 6hdm:A, 6i03:A, 1lvh:A, 1lvh:B, 1o03:A, 1o08:A, 5o6p:A, 5o6r:A, 5ojz:A, 5ok0:A, 5ok1:A, 5ok2:A, 5olw:B, 5olx:A, 5oly:A, 5oly:G, 8q1c:A, 8q1c:B, 8q1d:A, 8q1e:A, 8q1f:A, 8q1f:B, 6qzg:A, 6qzg:B, 2wf5:A, 2wf6:A, 2wf7:A, 2wf8:A, 2wf9:A, 2wfa:A, 2whe:A, 6ydj:A, 6ydk:A, 6ydl:A, 6ydm:A, 6ydm:B, 1z4n:A, 1z4n:B, 1z4o:A, 1z4o:B, 3zi4:A, 1zol:A
28 5euh:D 142 67 0.0488 0.1479 0.3134 7.5 5euh:C
29 6mcw:A 446 134 0.0767 0.0740 0.2463 8.3 7jj1:A, 7jj1:B, 7jj1:C, 6mi0:A, 7snm:A, 7snm:B, 7snm:C, 7snm:D
30 5jwq:A 413 76 0.0465 0.0484 0.2632 8.5 5jwq:C
31 7v3x:O 461 64 0.0419 0.0390 0.2812 9.2 7dy2:D, 7dy2:G, 7dy2:H, 7dy2:L, 7dye:A, 7dye:B, 7dyi:A, 7dyi:B, 7dyj:A, 7dyj:B, 7dyk:A, 7dyk:B, 7v3x:N, 7v3x:P, 7v3x:X, 7v3x:S, 7wdc:A, 7wdc:B, 8wv8:A, 8wv8:B, 8wve:A, 8wve:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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