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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
SERDKAMDKIEKAYELISNEYVEKVDREKLLEGAIQGMLSTLNDPYSVYMDKQTAKQFSDSLDSSFEGIGAEVGMEDGKI
IIVSPFKKSPAEKAGLKPNDEIISINGESMAGKDLNHAVLKIRGKKGSSVSMKIQRPGTKKQLSFRIKRAEIPLETVFAS
EKKVQGHSVGYIAISTFSEHTAEDFAKALRELEKKEIEGLVIDVRGNPGGYLQSVEEILKHFVTKDQPYIQIAERNGDKK
RYFSTLTHKKAYPVNVITDKGSAAASEILAGALKEAGHYDVVGDTSFGKGTVQQAVPMGDGSNIKLTLYKWLTPNGNWIH
KKGIEPTIAIKQPDYFSAGPLQLKEPLKVDMNNEDVKHAQVLLKGLSFDPGREDGYFSKDMKKAVMAFQDQNKLNKTGVI
DTRTAETLNQQIEKKKSDEKNDLQLQTALKSLF

The query sequence (length=433) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 4c2c:A 433 433 0.9977 0.9977 0.9977 0.0 4c2d:A, 4c2d:B, 4c2d:C, 4c2f:A, 4c2g:A
2 4c2d:D 343 282 0.6443 0.8134 0.9894 0.0
3 4c2d:D 343 63 0.1455 0.1837 1.0000 9.14e-34
4 8sxg:A 366 356 0.3025 0.3579 0.3680 1.12e-54 8sxe:A, 8sxe:B, 8sxf:A, 8sxh:A, 8sxh:E, 8sxh:I
5 8xud:D 651 311 0.2309 0.1536 0.3215 5.02e-24 6iqq:C, 6iqq:D, 5wql:D, 5wql:C, 8xud:C
6 1n6d:A 1023 270 0.1363 0.0577 0.2185 1.70e-04 1n6d:B, 1n6d:C, 1n6d:D, 1n6d:E, 1n6d:F, 1n6e:A, 1n6e:C, 1n6e:E, 1n6e:G, 1n6e:I, 1n6e:K, 1n6f:A, 1n6f:B, 1n6f:C, 1n6f:D, 1n6f:E, 1n6f:F
7 7w6z:A 414 156 0.0924 0.0966 0.2564 2.85e-04 7w6y:A
8 8b82:A 108 61 0.0439 0.1759 0.3115 0.001 8b82:B, 8b87:A, 8b87:B, 8bia:A, 8cd3:B, 6ms1:A, 6ms1:B, 6mtu:B, 6mtu:A, 6mtv:A, 6mtv:B, 6mye:A, 7qrs:B, 7qrs:A, 7qs9:A, 7qs9:B, 7qto:A, 7qto:B, 7qtp:A, 5vwk:D, 5vwk:C, 5vwk:B, 5vwk:A, 6xa8:B, 6xa8:A
9 2m0u:A 117 86 0.0670 0.2479 0.3372 0.002
10 2joa:A 105 56 0.0485 0.2000 0.3750 0.003
11 7xft:A 86 51 0.0462 0.2326 0.3922 0.010
12 1u38:A 89 59 0.0554 0.2697 0.4068 0.015
13 8blu:B 195 86 0.0670 0.1487 0.3372 0.019 5a2p:A, 5a2p:B, 5a2p:D, 5a2p:C, 8aai:A, 8aai:B, 8aai:C, 8aai:D, 8aak:A, 8aak:B, 8aao:A, 8aao:B, 8aap:A, 8aap:B, 6ak2:A, 6ak2:B, 8blu:C, 8blu:D, 8blv:A, 8blv:B, 7fsg:B, 7fsg:C, 7fsg:D, 7fsh:B, 7fsh:C, 7fsh:D, 7fsi:B, 7fsi:C, 7fsi:D, 7fsj:A, 7fsj:B, 7fsj:C, 7fsj:D, 7fsk:B, 7fsk:C, 7fsk:D, 7fsl:A, 7fsl:B, 7fsl:C, 7fsl:D, 7fsm:A, 7fsm:B, 7fsm:C, 7fsm:D, 7fsn:A, 7fsn:B, 7fsn:C, 7fsn:D, 7fso:B, 7fso:C, 7fso:D, 7fsp:B, 7fsp:C, 7fsp:D, 7fsq:B, 7fsq:A, 7fsq:C, 7fsq:D, 7fsr:B, 7fsr:C, 7fsr:D, 7fss:A, 7fss:B, 7fss:C, 7fss:D, 7fst:B, 7fst:C, 7fst:D, 7fsu:B, 7fsu:C, 7fsu:D, 7fsv:A, 7fsv:B, 7fsv:C, 7fsv:D, 7fsw:A, 7fsw:B, 7fsw:C, 7fsw:D, 7fsx:B, 7fsx:C, 7fsx:D, 7fsy:A, 7fsy:B, 7fsy:C, 7fsy:D, 7fsz:B, 7fsz:C, 7fsz:D, 7ft0:B, 7ft0:C, 7ft0:D, 7ft1:B, 7ft1:C, 7ft1:D, 7ft2:B, 7ft2:C, 7ft2:D, 7ft3:B, 7ft3:A, 7ft3:C, 7ft3:D, 7ft4:A, 7ft4:B, 7ft4:C, 7ft4:D, 7ft5:A, 7ft5:B, 7ft5:C, 7ft5:D, 7ft6:B, 7ft6:C, 7ft6:D, 7ft7:A, 7ft7:B, 7ft7:C, 7ft7:D, 7ft8:B, 7ft8:C, 7ft8:D, 7ft9:B, 7ft9:C, 7ft9:D, 7fta:B, 7fta:C, 7fta:D, 7ftb:B, 7ftb:C, 7ftb:D, 7ftc:B, 7ftc:C, 7ftc:D, 7ftd:A, 7ftd:C, 7ftd:B, 7ftd:D, 5g1d:B, 5g1d:A, 8hck:A, 8hu2:A, 1obx:A, 1oby:A, 1oby:B, 1obz:A, 6r9h:A, 6r9h:C, 6rlc:A, 6rlc:B, 6rlc:C, 6rlc:D, 1v1t:B, 1v1t:A, 1w9e:A, 1w9e:B, 1w9o:B, 1w9o:A, 1w9q:B, 1ybo:A, 1ybo:B, 4z33:A, 4z33:B
14 2m0v:A 128 36 0.0370 0.1250 0.4444 0.056
15 4wsi:A 372 49 0.0485 0.0565 0.4286 0.15 7m4r:A, 7ntj:B, 7ntj:A, 7ntk:A, 7ntk:D, 7ntk:B, 7ntk:F, 7qcs:A, 7qcs:B, 4uu5:A, 4wsi:B
16 6bxg:A 98 76 0.0624 0.2755 0.3553 0.17
17 2egn:A 83 35 0.0323 0.1687 0.4000 0.54
18 3dpm:A 522 68 0.0462 0.0383 0.2941 0.62 3dpm:B
19 2koh:A 111 66 0.0508 0.1982 0.3333 0.64 9imp:A, 9imp:B, 9imp:C, 9imp:D, 9imp:E, 9imp:F, 6jue:L, 2k20:A
20 7co7:D 329 74 0.0439 0.0578 0.2568 0.65 7co2:A, 7co3:A, 7co5:H, 7co5:B, 7co5:D, 7co5:F, 7co5:J, 7co5:L
21 4xhv:A 94 61 0.0416 0.1915 0.2951 0.84
22 3qgu:A 406 142 0.0808 0.0862 0.2465 0.91
23 5wou:A 95 64 0.0462 0.2105 0.3125 1.0
24 5tv7:A 158 84 0.0508 0.1392 0.2619 1.3 5tv7:B
25 3ch8:A 190 89 0.0554 0.1263 0.2697 1.7 2qbw:A
26 4izc:B 266 39 0.0323 0.0526 0.3590 2.0 4izc:A, 4izd:A, 4izd:B
27 8w7f:B 412 99 0.0600 0.0631 0.2626 3.5 8w75:D, 8w75:A, 8w75:B, 8w75:C, 8w78:A, 8w78:C, 8w78:B, 8w78:D, 8w7f:A, 8w7f:C, 8w7f:D
28 5c0p:A 284 96 0.0577 0.0880 0.2604 4.5
29 5heb:A 119 65 0.0462 0.1681 0.3077 4.6 1be9:A, 5d13:B, 5d13:A, 5d13:C, 5d13:D, 5hed:A, 5hey:A, 5hf1:A, 5hfb:A, 5hfc:A, 5hfe:A, 5hff:A, 1tp3:A, 1tp5:A
30 7qqm:A 413 181 0.1016 0.1065 0.2431 5.2
31 6ew9:A 305 72 0.0554 0.0787 0.3333 5.4 6ew9:B, 6ew9:C, 3gcn:A, 3gco:A, 3gds:A, 3gdu:A, 3gdu:C, 3gdv:A, 3gdv:C, 2r3y:B, 2r3y:C, 1soz:A, 1soz:B
32 1yag:A 372 113 0.0762 0.0887 0.2920 5.7 8a5a:V, 8a5d:V, 8a5o:V, 8a5p:V, 8a5q:V, 5i9e:D, 5nbl:C, 5nbl:D, 5nbm:C, 5nbm:D, 5nbn:C, 5nbn:D, 8thx:A, 8thx:B, 8thx:C, 8thx:D, 8thx:E, 8thy:A, 8thy:B, 8thy:C, 8thy:D, 8thy:E, 8ti3:A, 8ti3:B, 8ti3:C, 8ti3:D, 8ti3:E, 7vvy:G, 7vvz:G, 1yvn:A
33 2kqf:A 96 43 0.0346 0.1562 0.3488 6.4 2kyl:A
34 1rzx:A 98 29 0.0323 0.1429 0.4828 7.3 5i7z:A, 1x8s:A
35 2os6:A 89 62 0.0439 0.2135 0.3065 7.6
36 7cww:A 350 62 0.0370 0.0457 0.2581 9.6
37 2r4h:C 98 98 0.0647 0.2857 0.2857 9.9

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218