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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
SEIVKFNPVMASGFGAYIDHRDFLEAKTETIKNLLMRQGFVVVKNLDIDSDTFRDIYSAYGTIVEDTLKLEGEKGKIVTG
RGQLPFHADGGLLLSQVDQVFLYAAEIKNVKFRGATTVCDHALACQEMPAHLLRVLEEETFEVRVLWFKVPVFTDLGWVR
KMLIYFPFDEGQPASWEPRIVGFTDHETQAFFQELGAFLKQPRYYYKHFWEDGDLLIMDNRRVIHEREEFNDDDIVRRLY
RGQTAD

The query sequence (length=246) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 1nx4:C 250 249 1.0000 0.9840 0.9880 0.0 1nx4:A, 1nx8:A, 1nx8:C
2 4oj8:B 271 271 1.0000 0.9077 0.9077 2.15e-178 1nx4:B, 1nx8:B, 4oj8:A, 4oj8:C
3 5j92:B 259 174 0.1667 0.1583 0.2356 6.67e-07 5j92:A, 5j92:C, 5j92:D
4 5keu:B 280 63 0.0854 0.0750 0.3333 0.006 5keu:A
5 3swt:B 246 61 0.0894 0.0894 0.3607 0.016 3swt:A
6 5bke:E 255 72 0.0772 0.0745 0.2639 0.037 5bke:F, 5bke:G
7 5bke:C 289 72 0.0772 0.0657 0.2639 0.041 5bke:A, 5bke:B, 5bke:D
8 8evo:B 242 53 0.0691 0.0702 0.3208 0.053 4cvy:A, 4cvy:B, 4cvy:C, 4cvy:D
9 7tcl:X 259 40 0.0650 0.0618 0.4000 0.065
10 6edh:A 281 47 0.0610 0.0534 0.3191 0.15 6edh:B, 1gqw:A, 1gqw:B, 1gy9:A, 1gy9:B, 1os7:A, 1os7:B, 1os7:C, 1os7:D
11 4j5i:E 250 61 0.0854 0.0840 0.3443 0.70 4j5i:A, 4j5i:D, 4j5i:F, 4j5i:H
12 6f2a:C 326 32 0.0528 0.0399 0.4062 0.81 6f2a:A, 6f2a:B, 6f2a:D, 6f2b:A, 6f2b:B, 6f2b:C, 6f2b:D, 6f6j:A, 6f6j:B, 6f6j:C, 6f6j:D
13 4j5i:B 285 61 0.0854 0.0737 0.3443 0.87 4j5i:C, 4j5i:G
14 6npb:B 378 38 0.0569 0.0370 0.3684 0.88 6npb:A, 6npc:A, 6npc:B, 6npd:A, 6npd:B
15 3r1j:A 246 61 0.0732 0.0732 0.2951 0.94 3r1j:B
16 2qpx:A 376 75 0.0854 0.0559 0.2800 1.3
17 1oij:C 238 47 0.0610 0.0630 0.3191 1.4 1oii:C, 1oij:D
18 4q86:B 583 46 0.0650 0.0274 0.3478 1.6 4q85:A, 4q85:B, 4q85:C, 4q85:D, 4q85:E, 4q85:G, 4q85:H, 4q86:A, 4q86:C, 4q86:D, 4q86:E, 4q86:G, 4q86:H
19 1vz4:D 259 47 0.0610 0.0579 0.3191 1.6 1oii:A, 1oii:B, 1oii:D, 1oij:A, 1oij:B, 1oik:A, 1oik:D, 1vz4:A
20 1ds1:A 323 23 0.0488 0.0372 0.5217 1.8 1drt:A, 1dry:A, 1gvg:A
21 2q4a:B 322 22 0.0407 0.0311 0.4545 2.4 2q4a:A, 1y0z:A, 1y0z:B
22 4dcm:A 360 75 0.0854 0.0583 0.2800 4.2
23 2fge:A 979 72 0.0772 0.0194 0.2639 4.5 2fge:B
24 3e7g:C 423 48 0.0610 0.0355 0.3125 5.2 4cx7:A, 4cx7:D, 4cx7:B, 4cx7:C, 3e7g:A, 3e7g:B, 3e7g:D, 3ej8:A, 3ej8:B, 3ej8:C, 3ej8:D, 4nos:A, 4nos:B, 4nos:C, 4nos:D, 1nsi:A, 1nsi:B, 1nsi:C, 1nsi:D, 2nsi:A, 2nsi:B, 2nsi:C, 2nsi:D
25 6daw:A 342 19 0.0447 0.0322 0.5789 6.1 6daw:B
26 3v17:A 276 47 0.0528 0.0471 0.2766 7.8 3v17:C, 3v17:B, 3v17:D
27 3iso:A 218 106 0.1138 0.1284 0.2642 7.8 3iso:B, 4l5l:A, 4l5l:B, 4l5o:A, 4l5o:C, 4l5o:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218