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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
SEIHMTGPMCLIENTNGRLMANPEALKILSAITQPMVVVAIVGLYRTGKSYLMNKLAGKKKGFSLGSTVQSHTKGIWMWC
VPHPKKPGHILVLLDTEGLGDVEKGDNQNDSWIFALAVLLSSTFVYNSIGTINQQAMDQLYYVTELTHRIRSKSSPDSAD
FVSFFPDFVWTLRDFSLDLEALTPDEYLTYSLKLKKGTSQKDETFNLPRLCIRKFFPKKKCFVFDRPVHRRKLAQLEKLQ
DEELDPEFVQQVADFCSYIFSNSKTKTLSGGIQVNGPRLESLVLTYVNAISSGDLPCMENAVLALAQIENSAAVQKAIAH
YEQQMGQKVQLPTETLQELLDLHRDSEREAIEVFIRSSFKDVDHLFQKELAAQLEKKRDDFCKQNQEASSDRCSALLQVI
FSPLEEEVKAGIYSKPGGYRLFVQKLQDLKKKYYEEPRKGIQAEEILQTYLKSKESMTDAILQTDQTLTEKEKEIEVERV
KAESAQASAKMLHEMQRKNEQMMEQKERSYQEHLKQLTEKMENDRVQLLKEQERTLALKLQEQEQLLKEGFQKESRIMKN
EIQDLQTKMRR

The query sequence (length=571) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 8r1a:A 587 581 0.9912 0.9642 0.9742 0.0 2b8w:A, 2b8w:B, 2b92:A, 2b92:B, 2bc9:A, 8cqb:A, 8cqb:B, 2d4h:A, 1f5n:A, 6loj:B, 8r1a:B, 8r1a:C, 8r1a:D, 8r1a:E, 8r1a:F
2 6k1z:A 544 572 0.9317 0.9779 0.9301 0.0
3 7e5a:B 471 474 0.6095 0.7389 0.7342 0.0 7e5a:A
4 2d4h:B 284 298 0.4904 0.9859 0.9396 0.0
5 6vkj:A 305 305 0.4116 0.7705 0.7705 7.40e-177
6 7ckf:A 256 288 0.3292 0.7344 0.6528 2.51e-125 7ckf:B
7 7ol3:B 425 313 0.1226 0.1647 0.2236 1.07e-09 6b9e:A, 6b9f:A, 6b9f:B, 6b9g:B, 6b9g:C, 6b9g:D, 6b9g:A, 4idn:A, 4idn:B, 4ido:A, 4ido:B, 4idp:A, 4idp:B, 4idp:C, 4idp:D, 4idq:A, 4idq:B, 4idq:C, 4idq:D, 7ol3:A, 3q5d:A, 3q5e:A, 3q5e:C, 3qnu:A, 3qof:A, 3qof:B, 3qof:C, 3qof:D, 6xjn:A
8 5vgr:A 408 392 0.1734 0.2426 0.2526 5.43e-09 5vgr:B, 6xjo:A, 6xjo:B
9 3x1d:A 381 320 0.1401 0.2100 0.2500 3.90e-08
10 6b9e:B 387 372 0.1471 0.2171 0.2258 2.07e-06 6b9d:A, 6b9d:B, 3q5e:E, 3q5e:G
11 5ca9:A 656 90 0.0490 0.0427 0.3111 0.005 5ca8:A, 5cb2:A
12 6g0z:A 290 59 0.0420 0.0828 0.4068 0.12 6g0z:B, 6g12:A, 6g12:B, 6g14:B, 6g14:A, 6g15:A, 6g15:B
13 6llz:A 436 63 0.0350 0.0459 0.3175 0.33 7cyw:A, 6llw:A, 6llw:B, 6llz:B
14 5m7h:A 420 64 0.0350 0.0476 0.3125 1.1 4dcs:A, 4dct:A, 4dcu:A, 2hjg:A, 5mbs:A, 5x4b:A, 5x4b:B
15 3cnl:A 233 43 0.0385 0.0944 0.5116 3.3 3cnn:A, 3cno:A
16 3iev:A 302 68 0.0350 0.0662 0.2941 6.1 7c1o:A, 3r9w:A, 3r9x:A
17 7am2:BU 463 68 0.0368 0.0454 0.3088 6.2
18 7vdv:X 252 69 0.0315 0.0714 0.2609 8.5

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218