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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
SEFKKKLFWRAVVAEFLATTLFVFISIGSALGFKYPVGNNQTAVQDNVKVSLAFGLSIATLAQSVGHISGAHLNPAVTLG
LLLSCQISIFRALMYIIAQCVGAIVATAILSGITSSLTGNSLGRNDLADGVNSGQGLGIEIIGTLQLVLCVLATTDRRRR
DLGGSAPLAIGLSVALGHLLAIDYTGCGINPARSFGSAVITHNFSNHWIFWVGPFIGGALAVLIYDFILAPRSSDLTDRV
KVWTSGQ

The query sequence (length=247) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 8ct2:D 247 247 1.0000 1.0000 1.0000 2.47e-179 8ct2:B, 8ct2:C, 8ct2:A, 8cte:O, 8cte:S, 8cte:R, 8cte:M, 7uze:D, 7uze:B, 7uze:C, 7uze:A
2 4nef:A 239 242 0.4656 0.4812 0.4752 4.84e-77
3 8sjx:A 220 224 0.4453 0.5000 0.4911 2.43e-73 8sjy:A
4 5dye:D 253 236 0.4696 0.4585 0.4915 7.38e-70 5c5x:A, 5c5x:B, 5c5x:C, 5c5x:D, 5c5x:E, 5c5x:H, 3d9s:C, 3d9s:D, 5dye:A, 5dye:B, 5dye:C
5 5bn2:A 260 224 0.3117 0.2962 0.3438 1.40e-27
6 8uy6:A 244 215 0.3077 0.3115 0.3535 7.28e-25 3nka:A, 2o9e:A, 8uy6:C, 8uy6:E, 8uy6:G, 8uy6:I, 8uy6:K, 8uy6:M, 8uy6:O
7 2evu:A 245 246 0.3198 0.3224 0.3211 2.92e-20 2f2b:A
8 2evu:A 245 120 0.1417 0.1429 0.2917 9.54e-05 2f2b:A
9 1fx8:A 254 206 0.2591 0.2520 0.3107 1.17e-14
10 8c9h:A 253 253 0.2915 0.2846 0.2846 6.96e-11 8c9h:B, 8c9h:C, 8c9h:D, 8c9h:E, 8c9h:F, 8c9h:G, 8c9h:H, 6n1g:A, 6n1g:C, 6n1g:B, 6n1g:D, 6qzi:A, 6qzj:A
11 8jy6:A 242 251 0.2753 0.2810 0.2709 1.79e-09 8jy6:B, 8jy6:C, 8jy6:D, 8jy8:A, 8jy8:B, 8jy8:C, 8jy8:D
12 6f7h:C 253 257 0.2551 0.2490 0.2451 4.75e-09 6f7h:A, 6f7h:B
13 3c02:A 242 112 0.1336 0.1364 0.2946 3.36e-06
14 8vc1:A 391 57 0.0850 0.0537 0.3684 1.9 8uvu:A, 8uvu:B, 8uvu:C, 8uvu:D, 8vc1:B, 8vc1:C, 8vc1:D, 8vv3:A, 8vv3:B, 8vv3:C, 8vv3:D
15 8b0e:AAA 440 32 0.0607 0.0341 0.4688 2.7 8b0d:AAA, 7psj:A
16 6nb2:B 424 49 0.0688 0.0401 0.3469 3.0 6nb2:A, 6nbm:A, 6nbm:B
17 2a9n:M 109 46 0.0607 0.1376 0.3261 4.0
18 3gbf:A 415 58 0.0729 0.0434 0.3103 4.5
19 6vor:C 218 34 0.0526 0.0596 0.3824 5.9
20 8uc0:A 422 52 0.0567 0.0332 0.2692 6.6 8qct:A, 8r8t:A, 8ubw:A, 8ubx:A, 8uby:A, 8ubz:A
21 3s2e:A 340 64 0.0769 0.0559 0.2969 8.6 3s1l:A, 3s1l:B, 3s1l:C, 3s1l:D, 3s2e:B, 3s2e:C, 3s2e:D, 3s2e:E, 3s2e:F, 3s2e:G, 3s2e:H, 3s2f:A, 3s2f:B, 3s2f:C, 3s2f:D, 3s2f:E, 3s2f:F, 3s2f:G, 3s2f:H, 3s2g:A, 3s2g:B, 3s2g:C, 3s2g:D, 3s2g:E, 3s2g:F, 3s2g:G, 3s2g:H, 3s2i:A, 3s2i:B, 3s2i:C, 3s2i:D, 3s2i:E, 3s2i:F, 3s2i:G, 3s2i:H
22 5yvg:A 830 62 0.0850 0.0253 0.3387 9.5 2h4m:B, 2ot8:B, 5yvh:A
23 8sgh:A 844 62 0.0850 0.0249 0.3387 9.5 7cyl:A, 4fdd:A, 4fq3:A, 2h4m:A, 5j3v:A, 5j3v:B, 4jlq:A, 4oo6:A, 2ot8:A, 5tqc:A, 7vpw:A, 5yvi:A, 2z5k:A, 2z5m:A, 2z5n:A, 2z5o:A
24 3vnz:A 466 31 0.0567 0.0300 0.4516 9.5 5g0m:A, 5g0q:A, 5l77:A, 8ogx:A, 8oht:AAA, 8ohu:AAA, 8ohv:AAA, 7psi:A, 7psk:A, 3vo0:A
25 3akk:A 296 18 0.0405 0.0338 0.5556 10.0 3akk:B, 3akk:C, 3akk:D, 3akl:A, 3akl:B, 3akl:C, 3akl:D

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218