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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
SEFGHRTLASTPALWASIPCPRSELRLDLVLPSGQSFRWREQSPAHWSGVLADQVWTLTQTEEQLHCTVYRSQASRPTPD
ELEAVRKYFQLDVTLAQLYHHWGSVDSHFQEVAQKFQGVRLLRQDPIECLFSFICSSNNNIARITGMVERLCQAFGPRLI
QLDDVTYHGFPSLQALAGPEVEAHLRKLGLGYRARYVSASARAILEEQGGLAWLQQLRESSYEEAHKALCILPGVGTKVA
DCICLMALDKPQAVPVDVHMWHIAQRDYSWHPTTAKGPCPQTNKELGNFFRSLWGPYAGWAFAVLFSADL

The query sequence (length=310) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 2xhi:A 316 313 0.9742 0.9557 0.9649 0.0 7ayy:AAA, 7ayy:BBB, 7ayy:CCC, 7ayy:DDD, 7ayy:EEE, 1ebm:A, 1fn7:A, 1hu0:A, 2i5w:A, 3ih7:A, 3ktu:A, 1lwv:A, 1lww:A, 1lwy:A, 1m3h:A, 1m3q:A, 1n39:A, 1n3a:A, 1n3c:A, 2nob:A, 2noe:A, 2nof:A, 2noh:A, 2noi:A, 2nol:A, 2noz:A, 6rlw:AAA, 6rlw:BBB, 6rlw:CCC, 6rlw:DDD, 6rlw:EEE, 6w0m:A, 6w0r:A, 6w13:A, 1yqk:A, 1yql:A, 1yqm:A, 1yqr:A
2 8bvx:A 316 311 0.8613 0.8449 0.8585 0.0 7ayz:AAA, 7ayz:BBB, 7ayz:CCC, 7az0:AAA, 7az0:BBB, 8bq7:A, 8cex:A, 8cey:A, 8cey:B, 8cey:C, 6g3y:A, 6g3y:B, 6g3y:C, 6g40:A, 6g40:B, 6g40:C, 7pz1:AAA, 7qel:AAA, 7qel:BBB, 7qel:CCC, 7z3y:AAA, 7z5b:A, 7z5b:B, 7z5b:C, 7z5r:A, 7z5r:B, 7z5r:C, 7zc7:A, 7zc7:B, 7zc7:C, 7zg3:A, 7zg3:B, 7zg3:C
3 4ejy:A 289 246 0.2452 0.2630 0.3089 3.01e-27 4ejy:B, 4ejz:A, 4ejz:B
4 3f10:A 292 289 0.2452 0.2603 0.2630 1.12e-24 3i0w:A, 3i0x:A
5 4uob:A 242 100 0.1226 0.1570 0.3800 2.17e-06 8a5g:A
6 8a5c:A 237 74 0.0806 0.1055 0.3378 0.010 8a5f:A, 4unf:A
7 7ef9:A 414 123 0.1129 0.0845 0.2846 0.093 7ef8:A
8 7yhq:A 393 102 0.0839 0.0662 0.2549 0.18
9 1kea:A 217 103 0.0806 0.1152 0.2427 0.20
10 7t18:A 439 177 0.1290 0.0911 0.2260 0.25 2aq4:A, 3bjy:A, 3osp:A, 7t19:A, 7t1a:A, 7t1b:A, 5wm1:A, 5wm8:A, 5wmb:A, 6x6z:A, 6x70:A, 6x71:A, 6x72:A, 6x73:A, 6x74:A, 6x75:A, 6x76:A, 6x77:A
11 8wa1:B 998 39 0.0419 0.0130 0.3333 0.26
12 8wa0:B 973 39 0.0419 0.0134 0.3333 0.27 8w9z:B
13 7rds:A 232 179 0.1484 0.1983 0.2570 0.69 7rdt:A
14 7yhp:A 374 96 0.0742 0.0615 0.2396 0.71 7yho:A
15 4p1v:C 291 47 0.0548 0.0584 0.3617 0.90 4p1v:A, 4p1v:B, 4p1v:D, 4p25:A, 4p25:B, 4p25:C, 4p25:D, 4p2n:B, 4p2n:A, 4p2n:C, 4p2n:D, 4p3i:A, 4p3i:B, 4p3i:C, 4p3i:D
16 7y5e:72 164 51 0.0484 0.0915 0.2941 1.4 7y5e:7N, 7y7a:77, 7y7a:7o
17 6vvt:C 883 40 0.0516 0.0181 0.4000 4.3
18 6sat:B 87 82 0.0710 0.2529 0.2683 7.3 6sat:A, 6scp:A, 6scp:B, 6scs:A, 6scs:B, 6scs:D, 6scs:E
19 6fon:A 252 67 0.0710 0.0873 0.3284 8.0 1do5:A, 1do5:B, 1do5:C, 1do5:D, 6fn8:A, 6fn8:B, 6fol:A, 6fol:D, 6fol:E, 6fol:H, 6fon:C, 6fp6:B, 6fp6:D, 6fp6:F, 6fp6:H, 6fp6:J, 6fp6:L, 6fp6:N, 6fp6:P, 6fp6:R, 6fp6:T, 6fp6:V, 6fp6:X, 2rsq:A
20 8pv1:La 108 51 0.0548 0.1574 0.3333 8.6 8pv2:La, 8pv3:La, 8pv4:La, 8pv5:La, 8pv6:La, 8pv7:La, 8pv8:La, 8pvk:La, 8pvl:La
21 1bxn:A 445 43 0.0452 0.0315 0.3256 9.4 1bxn:C, 1bxn:E, 1bxn:G
22 7xjn:A 322 77 0.0774 0.0745 0.3117 9.6 7xjn:B, 7xjn:C, 7xjn:D

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218