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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
SEALKVVARCRPLSRKEEAAGHEQILTMDVKLGQVTLRNPRAAPGELPKTFTFDAVYDASSKQADLYDETVRPLIDSVLQ
GFNGTVFAYGQTGTGKTYTMQGTWVEPELRGVIPNAFEHIFTHISRSQNQQYLVRASYLEIYQEEIRDLLSKRLELKENP
ETGVYIKDLSSFVTKNVKEIEHVMNLGNQTRSSRSHAIFIITVECSEHIRVGKLNLVDLAGSENLSLSALGNVIAALAHI
PYRDSKLTRLLQDSLGGNAKTIMVATLGPASHSYDESLSTLRFANRAKNIKNKPRVNEDPKDTLLR

The query sequence (length=306) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 3b6v:A 306 306 1.0000 1.0000 1.0000 0.0 3b6v:B
2 3b6u:B 343 338 0.7974 0.7114 0.7219 2.98e-178 3b6u:A
3 2vvg:B 309 314 0.5686 0.5631 0.5541 2.45e-113 2vvg:A
4 7a5e:A 338 340 0.5621 0.5089 0.5059 7.48e-110 7a5e:B
5 7a3z:A 307 313 0.5523 0.5505 0.5399 9.98e-109
6 1goj:A 354 344 0.5033 0.4350 0.4477 3.91e-86
7 5zo8:A 331 335 0.4739 0.4381 0.4328 4.75e-82 4a51:G, 4a51:E, 4a51:F, 4a5y:B, 4ap0:D, 4ap0:B, 2gm1:B, 2gm1:D, 6hky:C, 6trl:A, 8yhh:B, 5zo8:B, 5zo9:A, 5zo9:B
8 6ta3:K 334 337 0.4641 0.4251 0.4214 6.69e-80 4a1z:A, 4a1z:B, 4a28:B, 4a51:A, 4a51:B, 4a51:C, 4a51:D, 4ap0:A, 2fme:A, 6g6y:A, 2gm1:A, 2gm1:E, 6hkx:A, 6hky:A, 6hky:B, 3k5e:B, 6tiw:K, 2x2r:B, 2xae:A, 2xae:B, 6y1i:A, 6y1i:B, 6y1i:C, 8yhh:A, 3zcw:A, 4zca:B
9 4ap0:C 311 312 0.4542 0.4469 0.4455 8.97e-80
10 4aqv:C 361 349 0.4706 0.3989 0.4126 4.07e-79 4a28:A, 4a50:A, 4a5y:A, 4a5y:C, 4as7:A, 4b7b:A, 4bbg:A, 4bxn:A, 4bxn:B, 3cjo:A, 3cjo:B, 4ck6:C, 4ck7:C, 2fky:A, 2fky:B, 2fl2:A, 2fl2:B, 2fl6:A, 2fl6:B, 2fme:B, 2g1q:A, 2g1q:B, 6g6z:A, 6hkx:B, 3hqd:A, 3hqd:B, 2ieh:A, 2ieh:B, 1ii6:A, 1ii6:B, 3k3b:A, 3k3b:B, 3k5e:A, 3ken:A, 3l9h:A, 3l9h:B, 2pg2:A, 2pg2:B, 1q0b:A, 1q0b:B, 2q2y:A, 2q2y:B, 2q2z:A, 2q2z:B, 6ta4:K, 6tle:A, 6tle:B, 6trl:B, 2uyi:A, 2uyi:B, 2uym:A, 2uym:B, 2wog:A, 2wog:B, 2wog:C, 2x2r:A, 2x2r:C, 2x7c:A, 2x7c:B, 2x7d:A, 2x7d:B, 2x7e:A, 2x7e:B, 1x88:A, 1x88:B, 2xae:C, 1yrs:A, 1yrs:B, 4zca:A, 4zhi:A, 4zhi:B, 5zo7:A, 5zo7:B
11 4bn2:C 311 325 0.4739 0.4662 0.4462 2.26e-77
12 3wpn:A 309 317 0.4412 0.4369 0.4259 1.83e-75
13 7z2b:K 308 317 0.4216 0.4188 0.4069 7.30e-74
14 7eo9:A 351 341 0.4510 0.3932 0.4047 8.59e-74 7eob:A, 2hxf:C, 1i6i:A, 1ia0:K, 1vfv:A, 1vfw:A, 1vfx:A, 2zfi:A, 2zfj:A, 2zfk:A, 2zfl:A, 2zfm:A
15 6a20:A 395 339 0.4641 0.3595 0.4189 7.79e-73 6a1z:A, 7d8v:A, 3gbj:B, 5zbr:B, 5zbr:A, 5zbr:C, 5zbs:B, 5zbs:A
16 3zfd:A 340 339 0.4444 0.4000 0.4012 1.67e-72 3zfc:A
17 6zpi:C 332 296 0.4379 0.4036 0.4527 4.05e-72 4bn2:A, 4bn2:B, 6zph:B
18 5ocu:K 333 339 0.4444 0.4084 0.4012 2.57e-71 5ogc:K
19 7lxr:B 344 343 0.4444 0.3953 0.3965 2.01e-70 7lxr:A, 6vpo:C, 2wbe:C
20 5zbs:C 323 333 0.4575 0.4334 0.4204 3.70e-70 3gbj:A, 3gbj:C
21 8uto:N 389 370 0.4510 0.3548 0.3730 3.48e-69 2hxh:C, 1i5s:A, 8utn:K, 8utn:N, 8uto:K, 8utp:K, 8utp:N, 8utq:K, 8utr:K, 8utt:K, 8utt:N, 8utu:K, 8utv:K, 8uty:K, 8uty:N, 4uxp:C, 1vfz:A
22 2xt3:A 300 308 0.4150 0.4233 0.4123 2.27e-68 4a14:A
23 2y65:C 343 326 0.4477 0.3994 0.4202 2.32e-68 2y5w:A, 2y5w:B, 2y65:D, 2y65:B, 2y65:A
24 1t5c:A 322 333 0.4542 0.4317 0.4174 2.53e-68 8hfh:A, 6m4i:A, 6m4i:B, 1t5c:B
25 3x2t:A 311 317 0.4248 0.4180 0.4101 1.10e-67 2kin:A, 3kin:A, 3kin:C
26 7rx0:C 328 332 0.4281 0.3994 0.3946 1.87e-67 6mlq:C, 6mlr:C
27 1mkj:A 336 322 0.4216 0.3839 0.4006 2.16e-67 4atx:C, 1bg2:A, 4hna:K, 8ixa:Y, 8ixa:S, 8ixa:T, 8ixa:U, 8ixa:V, 8ixa:W, 8ixa:X, 8ixa:Z, 8ixa:a, 8ixb:l, 8ixb:g, 8ixb:k, 8ixb:m, 8ixd:Y, 8ixd:S, 8ixd:T, 8ixd:U, 8ixd:V, 8ixd:W, 8ixd:X, 8ixd:Z, 8ixd:a, 8ixe:l, 8ixe:h, 8ixe:p, 8ixe:q, 8ixf:Y, 8ixf:S, 8ixf:T, 8ixf:U, 8ixf:V, 8ixf:W, 8ixf:X, 8ixf:Z, 8ixf:a, 8ixg:l, 8ixg:h, 8ixg:p, 8ixg:q, 3j8y:K, 2p4n:K
28 3lre:B 300 313 0.4346 0.4433 0.4249 3.08e-67 3lre:A, 7rsi:C
29 7nba:K 331 336 0.4412 0.4079 0.4018 5.21e-67
30 4uy0:C 333 336 0.4281 0.3934 0.3899 2.19e-63
31 7rs5:K 346 287 0.4020 0.3555 0.4286 3.93e-63 7rs5:a, 7rs5:b, 7rs5:c, 7rs5:d, 7rs5:e, 7rs5:f, 7rs5:g, 7rs5:h, 7rs6:K, 7rs6:a, 7rs6:b, 7rs6:c, 7rs6:d, 7rs6:e, 7rs6:f, 7rs6:g, 7rs6:h
32 2owm:A 328 304 0.3987 0.3720 0.4013 2.36e-62 2owm:B, 2owm:C, 2owm:D
33 6s8m:K 344 296 0.4020 0.3576 0.4155 3.79e-61
34 6wwk:K 368 371 0.4216 0.3505 0.3477 2.17e-60 7lvq:K, 7lvr:K, 6wwf:K, 6wwg:K, 6wwg:N, 6wwh:K, 6wwh:N, 6wwj:K, 6wwk:N, 6wwl:K, 6wwl:N, 6wwm:K, 6wwn:K, 6wwo:K, 6wwq:K, 6wwr:K, 6wws:K, 6wwu:K, 6wwv:K
35 7tr1:K 346 292 0.3889 0.3439 0.4075 2.76e-60 7lff:A, 7lff:B
36 5gsz:A 306 315 0.4183 0.4183 0.4063 2.83e-60
37 5wde:A 320 328 0.4118 0.3937 0.3841 5.60e-60
38 5hnw:K 329 329 0.4052 0.3769 0.3769 1.24e-59 5hle:A, 5hny:K, 3x2t:B
39 7tr3:K 418 290 0.3856 0.2823 0.4069 6.86e-59 7tqx:K, 7tqy:K, 7tr0:K
40 5m5i:C 369 315 0.4020 0.3333 0.3905 4.61e-58 5m5l:C, 5m5m:C, 5m5n:C, 5m5o:C
41 4ozq:B 687 325 0.3889 0.1732 0.3662 8.67e-57 4ozq:A
42 5mm7:K 397 315 0.3824 0.2947 0.3714 1.47e-55 5mm4:K
43 3cnz:A 333 318 0.3725 0.3423 0.3585 1.47e-55 3cnz:B
44 3h4s:A 359 322 0.3660 0.3120 0.3478 1.71e-54 4frz:A, 4frz:B
45 1cz7:D 365 272 0.3758 0.3151 0.4228 2.39e-54 1cz7:A, 1cz7:B, 1cz7:C, 3l1c:A, 1n6m:A, 2ncd:A, 3u06:A, 5w3d:A
46 4gkr:B 307 310 0.3856 0.3844 0.3806 1.20e-53 4gkr:A
47 7n61:0X 420 300 0.3693 0.2690 0.3767 3.04e-53 7n61:0Y, 7n61:0Z, 7n61:1A
48 3u06:B 344 259 0.3595 0.3198 0.4247 5.72e-53 3l1c:B, 1n6m:B
49 7wrg:A 812 366 0.4150 0.1564 0.3470 1.15e-52
50 7wrg:B 783 354 0.4052 0.1584 0.3503 2.83e-52
51 7x4n:E 332 340 0.3922 0.3614 0.3529 1.13e-51
52 3nwn:A 308 261 0.3497 0.3474 0.4100 3.97e-51
53 3cob:A 355 343 0.3791 0.3268 0.3382 5.90e-51 3cob:C, 1sdm:A
54 6nje:A 297 265 0.3562 0.3670 0.4113 7.28e-51
55 5wdh:A 296 255 0.3464 0.3581 0.4157 7.89e-51
56 5w3d:B 313 240 0.3333 0.3259 0.4250 4.47e-46
57 3t0q:A 304 272 0.3301 0.3322 0.3713 1.50e-45
58 4etp:A 379 278 0.3562 0.2876 0.3921 2.44e-45 1f9t:A, 1f9u:A, 1f9v:A, 3kar:A
59 4h1g:A 670 314 0.3627 0.1657 0.3535 6.03e-45
60 3dcb:A 299 258 0.3105 0.3177 0.3682 1.27e-42 3dc4:A, 3dco:N, 3pxn:A
61 6b0l:K 368 334 0.3562 0.2962 0.3263 1.35e-42 6b0c:K
62 5nd2:C 280 301 0.3235 0.3536 0.3289 3.42e-42
63 6bbn:E 378 320 0.3497 0.2831 0.3344 3.94e-42 2gry:A
64 1f9w:A 300 263 0.3431 0.3500 0.3992 3.52e-41 1f9w:B
65 5xja:A 337 309 0.3333 0.3027 0.3301 3.72e-41 3edl:D, 2heh:A, 4ubf:B, 4ubf:C, 4ubf:D, 1v8k:A, 5xja:B, 5xjb:B, 4y05:A
66 5nd7:C 300 316 0.3235 0.3300 0.3133 2.39e-40
67 5nd4:C 337 346 0.3399 0.3086 0.3006 7.48e-40
68 4ubf:A 309 297 0.3235 0.3204 0.3333 6.25e-39
69 5mio:C 477 328 0.3333 0.2138 0.3110 7.92e-37 1v8j:A, 5xjb:A
70 8bjs:A 343 354 0.3203 0.2857 0.2768 2.89e-34
71 6l47:A 416 69 0.0752 0.0553 0.3333 0.015 6l47:B, 6l48:B, 6l48:A, 6p2j:A, 6p2j:B, 6p2p:A, 6p2p:B, 6p2p:C, 6p2p:D, 6vum:A, 6vum:B, 6vum:C, 6vum:D
72 2qby:A 366 140 0.1307 0.1093 0.2857 0.073
73 7jps:E 386 101 0.1046 0.0829 0.3168 0.32 7cte:E, 7ctf:E, 7ctg:E
74 7jpp:E 406 101 0.1046 0.0788 0.3168 0.33 7jpo:E, 7jpq:E, 7jpr:E, 5uj7:E, 5uj7:F
75 5ujm:E 357 99 0.1046 0.0896 0.3232 0.35
76 1l8q:A 321 43 0.0490 0.0467 0.3488 0.67 2hcb:A, 2hcb:B, 2hcb:C, 2hcb:D, 3r8f:A, 3r8f:B, 3r8f:C, 3r8f:D
77 3tmb:B 318 81 0.0719 0.0692 0.2716 1.1 3tm8:A, 3tm8:B, 3tmb:A, 3tmc:A, 3tmc:B, 3tmd:A
78 6y2n:A 306 81 0.0556 0.0556 0.2099 3.2
79 4cvh:A 391 33 0.0392 0.0307 0.3636 3.5
80 5e8j:A 310 127 0.0882 0.0871 0.2126 4.1 3bgv:A, 3bgv:B, 3bgv:C, 3bgv:D, 5e8j:B, 5e9j:A, 5e9j:B, 5e9w:A, 5e9w:B, 5e9w:C, 5e9w:D, 3epp:A, 3epp:B, 8q69:A, 8q69:B, 8q8g:A, 8q8g:B, 8q9w:A, 8q9w:B
81 8r6f:H 184 62 0.0621 0.1033 0.3065 4.7 8ip8:hb, 8ip9:hb, 8ipa:hb, 8ipb:hb, 8jiw:BH, 4v7e:BH
82 3r03:A 131 68 0.0686 0.1603 0.3088 5.3
83 7d4i:A9 128 37 0.0490 0.1172 0.4054 6.4 7aju:UI, 7d5s:A9, 7d63:A9, 6ke6:A9, 6lqp:A9, 6lqq:A9, 6lqr:A9, 6lqs:A9, 6lqt:A9, 6lqu:A9, 6lqv:A9, 6zqb:UI
84 7aih:Aq 258 89 0.0850 0.1008 0.2921 6.6 7ane:Aq
85 3i5x:A 509 69 0.0654 0.0393 0.2899 6.6 4db2:C, 4db2:A, 4db2:B, 4db2:D, 4db4:A, 3i5y:A, 3i61:A, 3i62:A, 3sqw:A, 3sqx:A, 4tyn:A, 4tyw:A, 4tyy:A, 4tz0:A, 4tz6:A
86 4wt7:A 294 26 0.0327 0.0340 0.3846 7.0 4wt7:B
87 4ppv:A 246 52 0.0523 0.0650 0.3077 7.2 4ppu:A
88 6h0n:A 377 53 0.0458 0.0371 0.2642 7.3 6h0n:B, 6h0p:A, 6h0p:B
89 2z4r:A 240 30 0.0458 0.0583 0.4667 8.5 2z4r:B, 2z4r:C, 2z4s:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218