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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
SDPVRQYLHEIGQVPLLTLEEEVELARKVEEGMEAIKKLSEITGLDPDLIREVVRAKILGSARVRHIPGLKETLDPKTVE
EIDQKLKSLPKEHKRYLHIAREGEAARQHLIEANLRLVVSIAKKYTGRGLSFLDLIQEGNQGLIRAVEKFEYKRRFKFST
YATWWIRQAINRAIADQARTIRIPVHMVETINKLSRTARQLQQELGREPTYEEIAEAMGPGWDAKRVEETLKIAQEPVSL
EGDFIPDEHLPSPVDAATQSLLSEELEKALSKLSEREAMVLKLRKGLIDGREHTLEEVGAFFGVTRERIRQIENKALRKL
KYHESRTRKLRDFLD

The query sequence (length=335) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 7rdq:F 349 346 1.0000 0.9599 0.9682 0.0 2a68:F, 2a68:P, 2a69:F, 2a69:P, 6cuu:F, 5d4c:F, 5d4c:P, 5d4d:F, 5d4d:P, 5d4e:F, 5d4e:P, 5e17:F, 5e18:F, 7eh0:F, 7eh1:F, 7eh2:F, 7eh2:P, 4g7h:F, 4g7h:P, 4g7o:F, 4g7o:P, 4g7z:F, 4g7z:P, 5i2d:F, 5i2d:Q, 1iw7:F, 1iw7:P, 4ki2:A, 4ki2:B, 6kqd:F, 6kqd:P, 6kqe:F, 6kqf:F, 6kqg:F, 6kqh:F, 6kql:F, 6kqm:F, 6kqn:F, 1ku7:A, 6l74:F, 6lts:F, 7mlb:F, 7mli:F, 7mlj:F, 3n97:A, 4oin:F, 4oio:F, 4oip:F, 4oiq:F, 4oir:F, 6ovr:F, 6ovy:F, 6ow3:F, 6oy5:F, 6oy6:F, 6oy7:F, 6p70:F, 6p71:F, 4q4z:F, 4q5s:F, 1rio:H, 1smy:F, 5tjg:F, 3ugo:A, 3ugp:A, 5vo8:F, 5voi:F, 8w8n:F, 8w8o:F, 8w8p:F, 6wox:F, 6woy:F, 5x21:F, 5x22:F, 5x22:P, 4xln:F, 4xln:L, 4xlp:F, 4xlp:L, 4xlq:F, 4xlq:L, 4xlr:F, 4xlr:L, 4xls:F, 4xls:L
2 6bzo:F 326 346 0.5104 0.5245 0.4942 1.40e-104 6c04:F, 6cce:F, 6ccv:F, 6dcf:F, 6edt:F, 6ee8:F, 6eec:F, 6fbv:F, 8hih:F, 7kif:F, 7kim:F, 7kin:F, 6m7j:F, 6ono:B, 6ono:D, 6onu:B, 6onu:D, 6onu:F, 6onu:H, 7p5x:AF, 5tw1:F, 7u22:F, 5uh5:F, 5uh6:F, 5uh8:F, 5uh9:F, 5uha:F, 5uhb:F, 5uhc:F, 5uhd:F, 5uhe:F, 5uhf:F, 5uhg:F, 5vi5:F, 5vi8:F, 6vvs:F, 6vvt:F, 6vvv:F, 6vvx:F, 6vvy:F, 6vvz:F, 6vw0:F
3 8k60:F 315 345 0.5194 0.5524 0.5043 5.10e-104 8dy7:F, 8dy9:F, 8hvr:F, 8jke:F, 7vpd:F, 7vpz:F, 7x74:F, 7x75:F, 7x76:F
4 7ckq:F 272 257 0.4925 0.6066 0.6420 1.74e-101 7f75:F, 8x6f:E
5 7ckq:F 272 37 0.0627 0.0772 0.5676 1.15e-04 7f75:F, 8x6f:E
6 6n60:F 318 349 0.5134 0.5409 0.4928 3.68e-100 8igr:L, 8igs:L
7 7ye1:F 497 283 0.4716 0.3179 0.5583 3.91e-95 7ye2:F, 5yix:A
8 7ye1:F 497 41 0.0567 0.0382 0.4634 0.004 7ye2:F, 5yix:A
9 7l7b:F 272 257 0.4955 0.6103 0.6459 5.77e-95
10 7l7b:F 272 38 0.0657 0.0809 0.5789 1.30e-05
11 8u3b:F 431 248 0.4448 0.3457 0.6008 4.02e-91
12 8u3b:F 431 37 0.0478 0.0371 0.4324 2.71e-04
13 3iyd:F 479 247 0.4448 0.3111 0.6032 3.47e-90
14 6psr:L 548 248 0.4448 0.2719 0.6008 9.84e-90 6n58:L, 6n61:F
15 6psr:L 548 37 0.0478 0.0292 0.4324 3.10e-04 6n58:L, 6n61:F
16 8h3v:G 314 344 0.4955 0.5287 0.4826 4.36e-88 8h40:G
17 4kn7:X 517 244 0.4358 0.2824 0.5984 2.64e-87
18 4kn7:X 517 37 0.0478 0.0309 0.4324 3.03e-04
19 6wmr:Z 470 241 0.4119 0.2936 0.5726 2.49e-82 6wmt:Z
20 6wmr:Z 470 32 0.0448 0.0319 0.4688 0.064 6wmt:Z
21 8gzg:F 314 344 0.4716 0.5032 0.4593 7.62e-82 8gzh:F
22 6n4c:F 558 242 0.4328 0.2599 0.5992 2.08e-80 8ad1:F, 6b6h:F, 7bef:F, 7beg:F, 7c17:F, 7c97:F, 6ca0:F, 7chw:F, 7dy6:F, 8ftd:L, 6jnx:F, 8jo2:F, 6k4y:F, 7khb:F, 7khc:F, 7khe:F, 7khi:F, 6ldi:F, 7mkd:L, 7mke:L, 7mki:L, 7mkj:L, 7n4e:F, 6n57:L, 6n62:F, 6oul:L, 6p18:F, 2p7v:B, 6pb4:F, 6pb5:F, 6pb6:F, 6psq:L, 6pss:L, 6pst:L, 6psu:L, 6psv:L, 6psw:L, 7szj:F, 8to1:L, 8to6:L, 8to8:L, 8toe:L, 8tom:L, 5vt0:L, 7vwy:F, 7vwz:F, 7w5w:F, 7w5x:F, 7w5y:F, 6wmu:F, 6xh7:F, 6xh8:F, 6xl5:F, 6xl9:F, 6xlj:F, 6xll:F, 8y6u:F, 4yln:F, 4yln:L, 4yln:R, 4ylo:F, 4ylo:L, 4ylo:R, 4ylp:F, 4ylp:L, 4ylp:R
23 6n4c:F 558 37 0.0478 0.0287 0.4324 2.88e-04 8ad1:F, 6b6h:F, 7bef:F, 7beg:F, 7c17:F, 7c97:F, 6ca0:F, 7chw:F, 7dy6:F, 8ftd:L, 6jnx:F, 8jo2:F, 6k4y:F, 7khb:F, 7khc:F, 7khe:F, 7khi:F, 6ldi:F, 7mkd:L, 7mke:L, 7mki:L, 7mkj:L, 7n4e:F, 6n57:L, 6n62:F, 6oul:L, 6p18:F, 2p7v:B, 6pb4:F, 6pb5:F, 6pb6:F, 6psq:L, 6pss:L, 6pst:L, 6psu:L, 6psv:L, 6psw:L, 7szj:F, 8to1:L, 8to6:L, 8to8:L, 8toe:L, 8tom:L, 5vt0:L, 7vwy:F, 7vwz:F, 7w5w:F, 7w5x:F, 7w5y:F, 6wmu:F, 6xh7:F, 6xh8:F, 6xl5:F, 6xl9:F, 6xlj:F, 6xll:F, 8y6u:F, 4yln:F, 4yln:L, 4yln:R, 4ylo:F, 4ylo:L, 4ylo:R, 4ylp:F, 4ylp:L, 4ylp:R
24 7f0r:F 278 242 0.3224 0.3885 0.4463 7.80e-59
25 6omf:F 278 226 0.3104 0.3741 0.4602 8.76e-58 5ipl:F, 5ipm:F, 5ipn:F, 6kj6:F, 6utv:FFF, 6utw:FFF, 6utx:FFF, 6uty:FFF, 6utz:FFF, 6uu0:FFF, 6uu1:FFF, 6uu2:FFF, 6uu3:FFF, 6uu4:FFF, 6uu5:FFF, 6uu6:FFF, 6uu7:FFF, 6uu8:FFF, 6uu9:FFF, 6uua:FFF, 6uub:FFF, 6uuc:FFF
26 7xya:F 302 92 0.1881 0.2086 0.6848 7.97e-35
27 7xya:F 302 45 0.0597 0.0662 0.4444 2.83e-05
28 7ubm:F 353 128 0.2000 0.1898 0.5234 1.85e-34 7ubn:F
29 7ubm:F 353 48 0.0896 0.0850 0.6250 4.27e-09 7ubn:F
30 7ubm:F 353 37 0.0478 0.0453 0.4324 1.62e-04 7ubn:F
31 8cwr:B 109 76 0.1284 0.3945 0.5658 1.75e-20 8cwt:B, 8cwt:D, 8cwt:F, 8cyf:B, 7kuf:B
32 8hkc:E 262 231 0.2060 0.2634 0.2987 5.40e-19
33 6pmi:F 239 201 0.1701 0.2385 0.2836 1.11e-11 6pmj:F
34 6pfv:G 223 192 0.1791 0.2691 0.3125 3.17e-11 6pfj:A, 6pfv:A, 6pfv:D
35 8x6g:H 244 240 0.1672 0.2295 0.2333 2.47e-09
36 6ido:A 86 54 0.0716 0.2791 0.4444 6.71e-05 6ido:B
37 5or5:A 95 56 0.0537 0.1895 0.3214 0.55
38 7zm7:E 353 78 0.0597 0.0567 0.2564 1.4 7zmb:E, 7zmg:E
39 4c4o:B 335 56 0.0478 0.0478 0.2857 1.4 4c4o:A, 4c4o:C, 4c4o:D, 3wle:A, 3wle:B, 3wle:C, 3wle:D, 3wlf:A, 3wlf:B, 3wlf:C, 3wlf:D, 3wnq:A, 3wnq:B, 3wnq:C, 3wnq:D
40 7lq4:A 192 62 0.0687 0.1198 0.3710 2.1
41 7x2y:A 342 45 0.0388 0.0380 0.2889 6.4 7x1x:A, 7x1x:B, 7x2y:B
42 4r9f:A 402 78 0.0657 0.0547 0.2821 7.0 4r9g:A, 4r9g:B
43 1b9h:A 384 67 0.0597 0.0521 0.2985 9.3 1b9i:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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