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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
SDLELHPPSYPWSHRGLLSSLDHTSIRRGFQVYKQVCSSCHSMDYVAYRHLVGVCYTEDEAKALAEEVEVQDGPNEDGEM
FMRPGKLSDYFPKPYPNPEAARAANNGALPPDLSYIVRARHGGEDYVFSLLTGYCEPPTGVSLREGLYFNPYFPGQAIGM
APPIYNEVLEFDDGTPATMSQVAKDVCTFLRWAAEPEHDHRKRMGLKMLLMMGLLLPLVYAMKRHKWSVLKSRKLAYRPP
K

The query sequence (length=241) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 2a06:D 241 241 1.0000 1.0000 1.0000 0.0 2a06:Q, 1bcc:D, 2bcc:D, 3bcc:D, 1be3:D, 1bgy:D, 1bgy:P, 4d6t:D, 4d6t:Q, 4d6u:D, 4d6u:Q, 7dgq:o, 7dgq:z, 7dgr:o, 7dgr:z, 7dgs:o, 7dgs:z, 7dkf:D1, 7dkf:P1, 6fo0:Q, 6fo0:D, 6fo2:Q, 6fo2:D, 6fo6:D, 6fo6:Q, 2fyu:D, 5gpn:P, 5gup:x, 5gup:8, 6haw:D, 8iao:AD, 8iao:Ad, 8iar:AD, 8iar:Ad, 8ib4:AD, 8ib4:Ad, 8ib7:AD, 8ib7:Ad, 8ib9:AD, 8ib9:Ad, 8ibc:AD, 8ibc:Ad, 8ibd:AD, 8ibd:Ad, 8ibg:AD, 8ibg:Ad, 8ic2:AD, 8ic2:Ad, 8ic5:AD, 8ic5:Ad, 8iog:B, 8iog:b, 5j4z:AD, 5j4z:AO, 5j7y:AD, 5j7y:AO, 5j8k:AD, 5j8k:AO, 5klv:D, 1l0l:D, 1l0n:D, 5luf:d, 5luf:p, 6nhg:D, 5nmi:D, 5nmi:Q, 1ntk:D, 1ntm:D, 1ntz:D, 1nu1:D, 7o37:D, 7o37:O, 7o3c:D, 7o3c:O, 7o3e:O, 7o3e:D, 7o3h:D, 7o3h:O, 5okd:D, 8p65:D, 8p65:Q, 1pp9:D, 1pp9:Q, 1ppj:D, 1ppj:Q, 8pw5:D, 8pw5:O, 8pw6:D, 8pw6:O, 8pw7:D, 8pw7:O, 6q9e:c1, 6q9e:c2, 6qbx:c1, 6qbx:c2, 6qc2:c1, 6qc2:c2, 6qc3:c1, 6qc3:c2, 6qc4:c1, 6qc4:c2, 7r3v:D, 1sqb:D, 1sqp:D, 1sqq:D, 1sqv:D, 1sqx:D, 7tay:D, 7tz6:D, 7tz6:Q, 8ugd:3D, 8ugd:3Q, 8uge:3D, 8uge:3Q, 8ugf:3D, 8ugf:3Q, 8ugg:3D, 8ugg:3Q, 8ugh:3D, 8ugh:3Q, 8ugi:3D, 8ugi:3Q, 8ugj:3D, 8ugj:3Q, 8ugk:3D, 8ugk:3Q, 8ugn:3D, 8ugn:3Q, 8ugr:3D, 8ugr:3Q, 8ugr:6D, 8ugr:6Q, 5xte:H, 5xte:U, 5xth:AH, 5xth:AU, 5xti:AH, 5xti:AU, 6xvf:D, 2ybb:D, 2ybb:d, 6zfs:D, 6zft:D, 6zfu:D
2 3cwb:D 241 240 0.8382 0.8382 0.8417 4.17e-149 3cwb:Q, 3h1h:D, 3h1h:Q, 3h1i:D, 3h1i:Q, 3h1j:D, 3h1j:Q, 3h1k:D, 3h1k:Q, 3h1l:D, 3h1l:Q, 3l70:D, 3l70:Q, 3l71:D, 3l71:Q, 3l72:D, 3l72:Q, 3l73:D, 3l73:Q, 3l74:D, 3l74:Q, 3l75:D, 3l75:Q, 3tgu:D, 3tgu:Q, 4u3f:D, 4u3f:Q
3 8ab6:D 244 237 0.5892 0.5820 0.5992 2.03e-107 8ab6:O, 8ab7:D, 8ab7:O, 8ab8:D, 8ab8:O, 8ab9:D, 8ab9:O, 8aba:D, 8aba:O, 8abb:D, 8abb:O, 8abe:D, 8abe:O, 8abf:D, 8abf:O, 8abg:D, 8abg:O, 8abh:D, 8abh:O, 8abi:D, 8abi:O, 8abj:D, 8abj:O, 8abk:D, 8abk:O, 8abl:D, 8abl:O, 8abm:D, 8abm:O, 8ac3:D, 8ac3:O, 8ac4:D, 8ac4:O, 8ac5:D, 8ac5:O
4 8q1b:D 245 236 0.5602 0.5510 0.5720 2.04e-105 8q1b:O
5 3cx5:O 248 238 0.5809 0.5645 0.5882 4.16e-103 3cx5:D, 3cxh:O, 3cxh:D, 8e7s:L, 8e7s:l, 8ec0:L, 8ec0:l, 1ezv:D, 6giq:D, 6giq:O, 6hu9:D, 6hu9:O, 2ibz:D, 1kb9:D, 1kyo:D, 1kyo:O, 1p84:D, 4pd4:D, 6t0b:D, 6t0b:O, 6t15:D, 6t15:O, 6ymx:D, 6ymx:O
6 7rja:D 244 237 0.5809 0.5738 0.5907 9.29e-101 7rja:N, 7rjb:D, 7rjc:D, 7rjd:D, 7rje:D, 7rje:N
7 8bel:E 244 231 0.5934 0.5861 0.6190 5.93e-96 8bel:O, 8bpx:AE, 8bpx:BE, 8bq5:AE, 8bq5:BE, 8bq6:AE, 8bq6:BE, 8e73:D, 8e73:P, 7jrg:D, 7jrg:P, 7jrp:D, 7jrp:P
8 8iuf:QD 241 238 0.4481 0.4481 0.4538 4.36e-72 8iuf:Qd, 8iuj:QD, 8iuj:Qd
9 2yiu:B 206 223 0.3112 0.3641 0.3363 3.98e-37 2yiu:E
10 1zrt:D 248 249 0.3071 0.2984 0.2972 1.55e-31 6xi0:D, 6xi0:Q, 6xkt:D, 6xkt:Q, 6xku:D, 6xku:Q, 6xkv:D, 6xkv:Q, 6xkw:D, 6xkw:Q, 6xkx:D, 6xkx:Q, 6xkz:D, 6xkz:Q, 1zrt:Q
11 8b6j:D 295 236 0.3029 0.2475 0.3093 2.00e-31 8b6j:d, 8bqs:D, 8bqs:d, 8gym:qD, 8gym:qd, 8gym:Qd, 8gym:QD, 8gzu:qD, 8gzu:qd, 8gzu:QD, 8gzu:Qd, 7tgh:3D, 7tgh:3d
12 2fyn:B 256 257 0.3402 0.3203 0.3191 4.03e-31 8asi:C, 8asi:G, 8asj:C, 8asj:G, 2fyn:E, 2fyn:H, 2fyn:K, 2fyn:N, 2fyn:Q, 5kkz:B, 5kkz:F, 5kkz:L, 5kkz:P, 5kli:B, 5kli:F, 5kli:L, 5kli:P, 6nhh:B, 6nhh:F, 6nin:B, 6nin:F, 6nin:L, 6nin:P, 6nin:T, 6nin:X, 2qjk:B, 2qjk:E, 2qjk:H, 2qjk:K, 2qjk:N, 2qjk:Q, 2qjp:B, 2qjp:E, 2qjp:H, 2qjp:K, 2qjy:B, 2qjy:E, 2qjy:H, 2qjy:K, 2qjy:N, 2qjy:Q, 7tce:B, 7tce:F, 7tce:L, 7tce:P, 7tlj:F, 7tlj:B
13 8smr:M 204 222 0.2158 0.2549 0.2342 2.22e-09 8snh:M
14 8smr:J 232 253 0.2407 0.2500 0.2292 1.40e-06 8snh:J
15 8wql:VD 135 35 0.0415 0.0741 0.2857 0.16 1f1c:A, 1f1c:B, 8wql:VE, 8wql:V1, 8wql:v1, 8wql:vD, 8wql:vE
16 6kls:C 236 142 0.1660 0.1695 0.2817 0.19 6kls:F, 6klv:C, 6klv:F
17 4b6f:A 645 139 0.1245 0.0465 0.2158 0.52 1a1v:A, 4a1t:A, 4a1t:B, 4a1v:A, 4a1v:B, 4a1x:A, 4a1x:B, 4a92:A, 4a92:B, 4b6e:B, 4b6f:B, 4b71:A, 4b71:B, 4b73:A, 4b73:B, 4b74:A, 4b74:B, 4b75:A, 4b75:B, 4b76:A, 4b76:B, 1bt7:A, 1cu1:A, 1cu1:B, 1dxp:A, 1dxp:B, 1dxw:A, 1dy8:A, 1dy8:B, 1dy9:A, 1dy9:B, 5e4f:A, 5e4f:B, 2f55:A, 2f55:B, 2f55:C, 6fe6:A, 5fps:A, 5fps:B, 5fpt:A, 5fpt:B, 5fpy:A, 5fpy:B, 1hei:A, 4i31:A, 4i31:B, 4i32:A, 4i32:B, 4i33:A, 4i33:B, 4jmy:A, 4jmy:B, 1jxp:A, 1jxp:B, 2k1q:A, 4k8b:A, 4k8b:B, 3kee:A, 3kee:B, 3kee:C, 3kee:D, 3kqh:B, 3kqh:A, 3kqk:B, 3kqk:A, 3kql:A, 3kql:B, 3kqn:A, 3kqu:A, 3kqu:B, 3kqu:C, 3kqu:D, 3kqu:E, 3kqu:F, 4ktc:A, 4ktc:C, 1ns3:A, 1ns3:B, 3o8b:A, 3o8b:B, 3o8c:A, 3o8c:B, 3o8d:A, 3o8d:B, 3o8r:A, 3o8r:B, 4ojq:A, 4ok3:A, 4ok5:A, 4ok6:A, 4oks:A, 4oks:B, 3oyp:A, 3oyp:B, 3p8n:A, 3p8n:B, 3p8o:A, 3p8o:B, 3rvb:A, 4tyd:A, 4tyd:D, 4tyd:B, 4tyd:E, 4tyd:C, 4tyd:F, 4tyd:G, 4tyd:M, 4tyd:H, 4tyd:J, 4tyd:L, 4tyd:K, 4u01:A, 4u01:B, 4u01:C, 4u01:D, 4u01:E, 4u01:F, 4u01:G, 4u01:H, 4u01:J, 1w3c:A, 1w3c:B, 4wxp:A, 4wxr:A, 4wxr:B, 2zjo:A
18 6sj2:B 503 95 0.1162 0.0557 0.2947 1.0 6sj0:A, 6sj0:B, 6sj1:A, 6sj1:B, 6sj2:A, 6sj3:A, 6sj3:B, 6sj4:A, 6sj4:B
19 2blf:B 81 18 0.0332 0.0988 0.4444 1.1 2bpb:B, 2c9x:B, 2ca3:B, 2ca4:B
20 8xr6:V 137 41 0.0415 0.0730 0.2439 6.2 8wb4:V, 8wb4:v, 8xr6:v
21 1kv9:A 664 22 0.0373 0.0136 0.4091 6.6
22 8bja:A 1563 27 0.0498 0.0077 0.4444 8.5
23 8bja:B 1638 27 0.0498 0.0073 0.4444 9.2
24 6gpa:A 314 66 0.0747 0.0573 0.2727 9.5 6gpa:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218