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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
SAKNVVLDHDGNLDDFVAMVLLASNTEKVRLIGALCTDADCFVENGFNVTGKIMCLMHNNMNLPLFPIGKSAATAVNPFP
KEWRCLAKNMDDMPILNIPENVELWDKIKAENEKYEGQQLLADLVMNSEEKVTICVTGPLSNVAWCIDKYGEKFTSKVEE
CVIMGGAVDVRGNVFLPSTDGTAEWNIYWDPASAKTVFGCPGLRRIMFSLDSTNTVPVRSPYVQRFGEQTNFLLSILVGT
MWAMGYYAWDALTAAYVVDQKVANVDPVPIDVVVDKQPNEGATVRTDAENYPLTFVARNPEAEFFLDMLLRSARAC

The query sequence (length=316) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 2ff2:B 327 327 1.0000 0.9664 0.9664 0.0 3b9g:A, 3b9g:B, 3epw:A, 3epw:B, 3epx:A, 3epx:B, 2ff1:A, 2ff1:B, 2ff2:A, 1hoz:A, 1hoz:B, 1hp0:A, 1hp0:B, 1kic:A, 1kic:B, 1kie:A, 1kie:B, 1r4f:A, 1r4f:B
2 4i72:A 328 326 0.6772 0.6524 0.6564 2.77e-156 4i70:A, 4i71:A, 4i72:B, 4i73:A, 4i73:B, 4i73:C, 4i73:D, 4i74:A, 4i75:A, 4i75:B
3 2c40:A 302 315 0.3101 0.3245 0.3111 6.42e-41 2c40:B
4 3mkm:A 311 297 0.2468 0.2508 0.2626 7.51e-14 3b9x:A, 3b9x:B, 3b9x:D, 3mkm:B, 3mkm:C, 3mkm:D, 3mkn:A, 3mkn:B, 3mkn:C, 3mkn:D, 1q8f:A, 1q8f:B, 1q8f:C, 1q8f:D
5 4wr2:A 308 319 0.2627 0.2695 0.2602 7.29e-13
6 3b9x:C 283 252 0.2215 0.2473 0.2778 1.53e-12
7 2mas:A 313 295 0.2437 0.2460 0.2610 3.27e-12 2mas:B, 2mas:C, 2mas:D
8 3g5i:A 305 223 0.2215 0.2295 0.3139 1.11e-11 3g5i:B, 3g5i:C, 3g5i:D, 1yoe:A
9 1ezr:A 312 294 0.2278 0.2308 0.2449 2.16e-11 8ctm:A, 8ctm:B, 8ctm:C, 8ctm:D, 1ezr:B, 1ezr:C, 1ezr:D
10 5tsq:A 312 295 0.2310 0.2340 0.2475 6.66e-11
11 6ba0:A 312 296 0.2373 0.2404 0.2534 2.61e-08 6ba0:B, 6ba0:C, 6ba0:D
12 4kpo:A 317 195 0.1614 0.1609 0.2615 6.04e-08 4kpo:B, 6zk5:A, 6zk5:B
13 4kpn:A 318 142 0.1392 0.1384 0.3099 2.64e-07 4kpn:B, 4kpn:C, 4kpn:D, 4kpn:E, 4kpn:F, 4kpn:G, 4kpn:H
14 5mj7:A 322 207 0.1835 0.1801 0.2802 2.78e-07 5mj7:B
15 6zk3:A 319 85 0.1013 0.1003 0.3765 2.66e-06 6zk1:A, 6zk1:B, 6zk1:C, 6zk1:D, 6zk2:A, 6zk2:B, 6zk2:C, 6zk2:D, 6zk3:B, 6zk3:C, 6zk3:D, 6zk3:E, 6zk3:F, 6zk4:A, 6zk4:B, 6zk4:C, 6zk4:D
16 6ba1:A 316 223 0.1867 0.1867 0.2646 6.99e-06 6ba1:B, 6ba1:C, 6ba1:D, 6ba1:E, 6ba1:F, 6ba1:G, 6ba1:H, 6ba1:I, 6ba1:J, 6ba1:K, 6ba1:L, 6ba1:M, 6ba1:N, 6ba1:O, 6ba1:P, 6ba1:Q, 6ba1:R
17 8qnd:A 297 122 0.1044 0.1111 0.2705 1.26e-04 8qnd:C, 8qnd:B, 8qnd:D
18 8oi7:A 346 250 0.1835 0.1676 0.2320 0.069 8oi7:B, 8oi9:A, 8oi9:B, 8oia:A, 8oia:B, 8oia:C, 8oia:D, 8oib:A, 8oib:B, 8oib:C, 8oib:D, 8oic:A, 8oic:B, 8oic:C, 8oic:D, 8oic:E, 8oic:F, 8oic:G, 8oic:H
19 3t8i:A 306 199 0.1614 0.1667 0.2563 0.16 3t8i:B, 3t8i:C, 3t8i:D
20 8db6:B 304 72 0.0696 0.0724 0.3056 0.46 8db6:A, 8db6:C, 8db6:D, 8db7:B, 8db7:A, 8db7:C, 8db7:D, 8db8:B, 8db8:A, 8db8:C, 8db8:D, 8db9:A, 8db9:B, 8db9:C, 8db9:D
21 4c12:A 493 72 0.0665 0.0426 0.2917 1.6 4c13:A
22 8rih:B 333 86 0.0601 0.0571 0.2209 1.6 8rih:A
23 7awt:G 907 64 0.0633 0.0221 0.3125 2.2 7nyr:G, 7nyu:G, 7nyv:G, 7nz1:G, 7p61:G, 7p62:G, 7p63:G, 7p64:G, 7p69:G, 7p7c:G, 7p7e:G, 7p7j:G, 7p7k:G, 7p7l:G, 7p7m:G, 7z7r:G, 7z7s:G, 7z7t:G, 7z7v:G, 7z80:G, 7z83:G, 7z84:G, 7zc5:G, 7zci:G
24 6bdo:D 395 94 0.0791 0.0633 0.2660 4.1 6bdo:B, 6bdo:A, 6bdo:C, 5kmp:A, 5kmp:B, 5kmq:A, 5kmq:B, 5kmq:C, 5kmq:D, 5kmr:B, 5kmr:A, 5kmr:C, 5kmr:D, 5kms:A, 5kms:B, 5kms:C, 5kms:D, 4nwz:A, 4nwz:B, 4nwz:C, 4nwz:D, 5wed:B, 5wed:A, 5wed:C, 5wed:D
25 8cro:C 390 22 0.0411 0.0333 0.5909 4.2
26 6wb6:A 653 65 0.0538 0.0260 0.2615 5.2 6wb6:B
27 3gvh:A 318 100 0.0918 0.0912 0.2900 7.3 3gvh:B, 3gvh:C, 3gvh:D, 3gvi:A, 3gvi:B, 3gvi:C, 3gvi:D, 3gvi:E, 3gvi:F
28 2xvk:A 944 49 0.0601 0.0201 0.3878 7.7 2xvl:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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