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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
SAKIVKPNGEKPDEFESGISQALLELEMNSDLKAQLRELNITAAKEIEVGGGRKAIIIFVPVPQLKSFQKIQVRLVRELE
KKFSGKHVVFIAQRRILPKPTRKKNKQKRPRSRTLTAVHDAILEDLVFPSEIVGKRIRVKLDGSRLIKVHLDKAQQNNVE
HKVETFSGVYKKLTGKDVNFEFPEFQ

The query sequence (length=186) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 4d5l:H 191 189 1.0000 0.9738 0.9841 3.20e-131 7a01:P3, 7a09:s, 5a2q:H, 5aj0:BH, 9bdl:AS07, 9bdn:AS07, 9bdp:AS07, 8bhf:I3, 9bkd:G, 9bln:G, 8btk:Ag, 7cpu:SH, 7cpv:SH, 4d61:H, 6d90:II, 6d9j:II, 9f1b:Ag, 9f1c:Ag, 9f1d:Ag, 6fec:X, 5flx:H, 6g18:H, 6g4s:H, 6g4w:H, 6g51:H, 6g53:H, 6g5h:H, 6g5i:H, 8g5y:SH, 8g5z:SH, 8g60:SH, 8g61:SH, 8g6j:SH, 8glp:SH, 6gz3:BH, 6gz4:BH, 6gz5:BH, 6hcf:I1, 6hcj:I2, 6hcm:I1, 6hcq:I2, 8ifd:2s, 8ife:2s, 6ip5:2s, 6ip6:2s, 6ip8:2s, 3j7p:SH, 3j7r:SH, 3jag:HH, 3jah:HH, 3jai:HH, 3jaj:SH, 3jan:SH, 8jdj:4, 8jdk:4, 8jdl:4, 8jdm:4, 7jqb:I, 7jqc:I, 5k0y:X, 8k2c:SH, 7k5i:H, 4kzx:H, 4kzy:H, 4kzz:H, 5lks:SH, 7ls1:t, 7ls2:t, 5lzs:HH, 5lzt:HH, 5lzu:HH, 5lzv:HH, 5lzw:HH, 5lzx:HH, 5lzy:HH, 5lzz:HH, 7mdz:HH, 7mqa:L7, 6mtb:HH, 6mtc:HH, 6mtd:HH, 6mte:HH, 7nwg:I2, 7nwh:HH, 7nwi:HH, 7o7y:Ag, 7o7z:Ag, 7o80:Ag, 7o81:Ag, 5oa3:H, 6ole:SH, 6olf:SH, 6olg:BH, 6oli:SH, 6olz:BH, 6om0:SH, 6om7:SH, 7oya:H2, 7oyb:H2, 7oyc:H2, 7oyd:HH, 8oz0:L, 8p03:J, 8p09:J, 8p2k:Ag, 6p4g:I, 6p4h:I, 6p5i:I, 6p5j:I, 6p5k:I, 6p5n:I, 8pj1:G, 8pj2:G, 8pj3:G, 8pj4:G, 8pj5:G, 8pj6:G, 8ppk:H, 8ppl:AH, 8q7z:Ag, 8q87:Ag, 7qgg:SH, 8qoi:SH, 7qp6:G, 7qp7:G, 7qvp:SH, 7qvp:RH, 6qzp:SH, 7r4x:H, 6r5q:BB, 6r6g:BB, 6r6p:y, 6r7q:BB, 8scb:HH, 6sgc:I1, 7syg:I, 7syh:I, 7syi:I, 7syj:I, 7syk:I, 7syl:I, 7sym:I, 7syn:I, 7syo:I, 7syp:I, 7syq:I, 7syr:I, 7sys:I, 7syt:I, 7syu:I, 7syv:I, 7syw:I, 7syx:I, 5t2c:At, 8t4s:H, 7toq:AS07, 7tor:AS07, 7tql:H, 7ucj:HH, 7uck:HH, 4ug0:SH, 4ujc:CH, 4ujd:CH, 4uje:BH, 4v6x:AH, 5vyc:H1, 5vyc:H2, 5vyc:H3, 5vyc:H4, 5vyc:H5, 5vyc:H6, 6w2s:I, 6w2t:I, 7wts:H, 7wtt:H, 7wtu:H, 7wtv:H, 7wtw:H, 7wtx:H, 7wtz:H, 7wu0:H, 6xa1:SH, 7xnx:SH, 7xny:SH, 8xsx:SH, 8xsy:SH, 8xsz:SH, 8xxl:SH, 8xxm:SH, 8xxn:SH, 6y0g:SH, 8y0w:SH, 8y0x:SH, 6y2l:SH, 6y57:SH, 6yal:J, 6yam:J, 6yan:J, 6ybw:G, 8yoo:SH, 8yop:SH, 6z6l:SH, 6z6m:SH, 6z6n:SH, 7zjw:SS, 7zjx:SS, 6zlw:H, 6zm7:SH, 6zme:SH, 6zmi:SH, 6zmo:SH, 6zmt:H, 6zmw:G, 6zn5:H, 6zoj:H, 6zok:H, 6zon:s, 6zp4:s, 6zuo:H, 6zv6:H, 6zvh:H, 6zvj:s, 6zvk:P3, 6zxd:H, 6zxe:H, 6zxf:H, 6zxg:H, 6zxh:H
2 4v6w:AH 194 186 0.7312 0.7010 0.7312 1.05e-94 6xu6:AH, 6xu7:AH, 6xu8:AH
3 9bh5:AH 192 187 0.5968 0.5781 0.5936 2.53e-76 9cai:AH
4 7old:SH 198 184 0.5699 0.5354 0.5761 2.49e-72 7olc:SH, 8oo0:SH, 7r81:I2, 7z3n:SH, 7z3o:SH
5 8auv:O 188 182 0.5538 0.5479 0.5659 1.71e-69 8b2l:O1, 7qix:H, 7qiz:x
6 8r6f:H 184 182 0.5538 0.5598 0.5659 5.10e-69 8ip8:hb, 8ip9:hb, 8ipa:hb, 8ipb:hb, 8jiw:BH, 4v7e:BH
7 8c3a:J 185 184 0.5538 0.5568 0.5598 4.53e-68 8c3a:CU, 8cq7:J, 8cq7:CU, 8cqw:J, 8cqw:CU, 8cre:J, 8cre:CU, 8oeq:J, 8oeq:CU, 7pzy:I, 7q08:I, 7q0f:I, 7q0p:I, 7q0r:I, 8q5i:I
8 5dat:s7 186 185 0.5484 0.5484 0.5514 4.51e-66 7a1g:U, 7ajt:DH, 7aju:DH, 7b7d:U, 8bn3:S7, 8bqd:U, 8bqx:U, 8c00:U, 8c01:U, 8c83:U, 8cah:U, 8cas:U, 8cbj:H, 8ccs:k, 8cdl:k, 8cdr:k, 8ceh:k, 8cf5:k, 8cg8:k, 8cgn:k, 8civ:k, 8cku:k, 8cmj:k, 7d4i:SI, 7d5t:SI, 7d63:SI, 5dat:S7, 5dc3:S7, 5dc3:s7, 5dge:S7, 5dge:s7, 5dgf:S7, 5dgf:s7, 5dgv:S7, 5dgv:s7, 6eml:U, 8eub:BH, 8evp:BH, 8evq:BH, 8evr:BH, 8evs:BH, 8evt:BH, 8ewb:BH, 8ewc:BH, 6fai:H, 5fci:S7, 5fci:s7, 5fcj:S7, 5fcj:s7, 6fyx:H, 6fyy:H, 6gq1:x, 6gqb:x, 6gqv:x, 6gsm:H, 6gsn:H, 6hhq:I, 6hhq:s7, 5i4l:S7, 5i4l:s7, 6i7o:U, 6i7o:Ub, 8i7j:H, 5it7:H, 5it9:H, 3j6x:S7, 3j6y:S7, 3j77:S7, 3j78:S7, 3j80:H, 3j81:H, 3jam:H, 3jap:H, 5juo:EB, 5jup:EB, 5jus:EB, 5jut:EB, 5juu:EB, 8k2d:SH, 8k82:SH, 6ke6:SI, 5ll6:U, 6lqp:SI, 6lqq:SI, 6lqr:SI, 5lyb:S7, 5lyb:s7, 5m1j:H2, 5mc6:U, 5mei:s7, 5mei:I, 7mpi:BH, 7mpj:BH, 7n8b:BH, 5ndg:S7, 5ndg:s7, 5ndv:S7, 5ndv:s7, 5ndw:S7, 5ndw:s7, 7nrc:SU, 7nrd:SU, 5obm:S7, 5obm:s7, 5on6:s7, 5on6:I, 7osa:eS7, 7osm:eS7, 6q8y:U, 6rbd:H, 6rbe:H, 7rr5:SH, 8rw1:H, 6s47:BI, 8s8d:H, 8s8e:H, 8s8f:H, 8s8g:H, 8s8h:H, 8s8i:H, 8s8j:H, 6snt:H, 6sv4:U, 6sv4:Ub, 6sv4:Uc, 6t4q:SH, 6t7i:SH, 6t7t:SH, 6t83:Hb, 6t83:i, 5tbw:I, 5tbw:s7, 6tb3:U, 5tga:S7, 5tga:s7, 5tgm:S7, 5tgm:s7, 6tnu:U, 4u3m:S7, 4u3m:s7, 4u3n:S7, 4u3n:s7, 4u3u:S7, 4u3u:s7, 4u4n:S7, 4u4n:s7, 4u4o:S7, 4u4o:s7, 4u4q:S7, 4u4q:s7, 4u4r:S7, 4u4r:s7, 4u4u:S7, 4u4u:s7, 4u4y:S7, 4u4y:s7, 4u4z:S7, 4u4z:s7, 4u50:S7, 4u50:s7, 4u51:S7, 4u51:s7, 4u52:S7, 4u52:s7, 4u53:S7, 4u53:s7, 4u55:S7, 4u55:s7, 4u56:S7, 4u56:s7, 4u6f:S7, 4u6f:s7, 4uer:3, 6uz7:H, 4v88:AH, 4v88:CH, 4v8y:AH, 4v8z:AH, 4v92:BH, 6wdr:H, 6woo:HH, 7wtl:SH, 7wtm:SH, 7wtn:SH, 7wto:SH, 7wtp:SH, 7wtq:SH, 7wtr:SH, 6xiq:x, 6xir:x, 8y0u:SH, 6y7c:H, 6z6j:SH, 6z6k:SH, 6zce:I, 7zpq:AH, 6zqa:DH, 6zqb:DH, 6zqc:DH, 6zqd:DH, 6zqe:DH, 6zqf:DH, 6zqg:DH, 7zrs:AH, 6zu9:U, 7zuw:AH, 7zux:DH, 6zvi:p, 7zw0:sU
9 6lqs:SI 164 176 0.4570 0.5183 0.4830 9.81e-52 6lqt:SI
10 5xxu:H 177 180 0.5000 0.5254 0.5167 2.58e-50
11 6zj3:SI 187 170 0.4247 0.4225 0.4647 1.68e-43
12 3j7a:J 188 187 0.4247 0.4202 0.4225 7.08e-42 3jbn:J, 3jbo:J, 3jbp:J, 6okk:J, 8tpu:SJ
13 8br8:SH 184 183 0.3925 0.3967 0.3989 3.09e-36 8brm:SH, 8bsi:SH, 8bsj:SH, 8btd:SH, 8btr:SH, 8fvy:H, 8g4s:H
14 8a98:SI 200 174 0.3495 0.3250 0.3736 5.61e-35 8a3w:SI, 6az1:I, 8ovj:SI, 8rxh:SI, 8rxx:SI, 5t2a:4
15 7ase:q 200 182 0.3710 0.3450 0.3791 9.36e-34 5opt:Q
16 8ova:A4 198 173 0.3602 0.3384 0.3873 3.38e-31 8ove:A4, 4v8m:A4
17 4bts:A3 196 174 0.3495 0.3316 0.3736 1.19e-29 4bts:B3, 4bts:C3, 4bts:D3, 4v5o:A3, 4v5o:B3
18 5xyi:H 163 150 0.3011 0.3436 0.3733 4.89e-25
19 7pwf:H 162 160 0.3226 0.3704 0.3750 3.25e-24 7pwo:H1
20 8p5d:SH0 163 151 0.2258 0.2577 0.2781 5.02e-07 8p60:SH0, 8p60:RH0, 7qca:SH0
21 5xxu:U 103 46 0.0914 0.1650 0.3696 1.1
22 4v4n:AA 216 96 0.1237 0.1065 0.2396 4.3 4v6u:BA
23 8fl4:SR 593 41 0.0806 0.0253 0.3659 5.4 8fkr:SR, 8fks:SR
24 6hiv:CO 361 73 0.1129 0.0582 0.2877 6.8 7aor:i, 6hiw:CO, 6hiy:CO, 7pua:CO, 7pub:CO, 6sga:CO, 6sgb:CO

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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