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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
SAIGVLTSGGDAQGMNAAVRAVVRMGIYVGAKVYFIYEGYQGMVDGGSNIAEADWESVSSILQVGGTIIGSARCQAFRTR
EGRLKAACNLLQRGITNLCVIGGDGSLTGANLFRKEWSGLLEELARNGQIDKEAVQKYAYLNVVGMVGSIDNDFCGTDMT
IGTDSALHRIIEVVDAIMTTAQSHQRTFVLEVMGRHCGYLALVSALACGADWVFLPESPPEEGWEEQMCVKLSENRARKK
RLNIIIVAEGAIDTQNKPITSEKIKELVVTQLGYDTRVTILGHVQRGGTPSAFDRILASRMGVEAVIALLEATPDTPACV
VSLNGNHAVRLPLMECVQMTQDVQKAMDERRFQDAVRLRGRSFAGNLNTYKRLAIKLPDDQIPKTNCNVAVINVGAPAAG
MNAAVRSAVRVGIADGHRMLAIYDGFDGFAKGQIKEIGWTDVGGWTGQGGSILGTKRVLPGKYLEEIATQMRTHSINALL
IIGGFEAYLGLLELSAAREKHEEFCVPMVMVPATVSNNVPGSDFSIGADTALNTITDTCDRIKQSASGTKRRVFIIETMG
GYCGYLANMGGLAAGADAAYIFEEPFDIRDLQSNVEHLTEKMKTTIQRGLVLRNESCSENYTTDFIYQLYSEEGKGVFDC
RKNVLGHMQQGGAPSPFDRNFGTKISARAMEWITAKLKEARFTTDDSICVLGISKRNVIFQPVAELKKQTDFEHRIPKEQ
WWLKLRPLMKILA

The query sequence (length=733) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 4xyj:A 768 737 0.9986 0.9531 0.9932 0.0 4rh3:A, 4rh3:B, 4rh3:C, 4rh3:D, 4u1r:A, 4u1r:B, 4u1r:C, 4u1r:D, 4wl0:A, 4wl0:B, 4wl0:C, 4wl0:D, 4xyj:B, 4xyj:C, 4xyj:D, 4xyj:E, 4xyj:F, 4xyj:G, 4xyj:H, 4xyk:A, 4xyk:B, 4xyk:C, 4xyk:D, 4xz2:A, 4xz2:B, 4xz2:C, 4xz2:D
2 3o8l:A 748 739 0.7299 0.7152 0.7240 0.0 3o8l:B, 3o8n:A, 3o8n:B
3 8w2h:A 761 738 0.6944 0.6689 0.6897 0.0 7lw1:A, 7lw1:D, 7lw1:E, 7lw1:F, 8w2g:A, 8w2g:B, 8w2g:D, 8w2g:C, 8w2h:B, 8w2h:C, 8w2h:D, 8w2j:E, 8w2j:F, 8w2j:G, 8w2j:H, 8w2j:A, 8w2j:B, 8w2j:C, 8w2j:D
4 3o8o:B 763 751 0.4407 0.4233 0.4301 0.0 3o8o:D, 3o8o:F, 3o8o:H
5 3o8o:E 752 743 0.4434 0.4322 0.4374 0.0 3o8o:A, 3o8o:C, 3o8o:G
6 3opy:B 884 759 0.4434 0.3676 0.4282 0.0 3opy:D, 3opy:F, 3opy:H
7 4i4i:A 319 310 0.1910 0.4389 0.4516 4.86e-72 4i4i:B, 4i4i:C, 4i4i:D, 4i7e:A, 4i7e:B, 4i7e:C, 4i7e:D, 1mto:A, 1mto:B, 1mto:C, 1mto:D, 1mto:E, 1mto:F, 1mto:G, 1mto:H, 3pfk:A, 4pfk:A, 6pfk:A, 6pfk:B, 6pfk:C, 6pfk:D
8 4i4i:A 319 288 0.1405 0.3229 0.3576 2.34e-47 4i4i:B, 4i4i:C, 4i4i:D, 4i7e:A, 4i7e:B, 4i7e:C, 4i7e:D, 1mto:A, 1mto:B, 1mto:C, 1mto:D, 1mto:E, 1mto:F, 1mto:G, 1mto:H, 3pfk:A, 4pfk:A, 6pfk:A, 6pfk:B, 6pfk:C, 6pfk:D
9 5xz7:A 322 309 0.1814 0.4130 0.4304 1.05e-66 5xz6:A, 5xz8:A, 5xz9:A, 5xza:A
10 5xz7:A 322 288 0.1282 0.2919 0.3264 9.29e-36 5xz6:A, 5xz8:A, 5xz9:A, 5xza:A
11 1pfk:A 320 308 0.1719 0.3937 0.4091 3.16e-59 1pfk:B
12 1pfk:A 320 291 0.1160 0.2656 0.2921 1.65e-37 1pfk:B
13 6qu3:A 464 373 0.1364 0.2155 0.2681 3.14e-18 3f5m:A, 3f5m:B, 3f5m:C, 3f5m:D, 6qu3:B, 6qu3:C, 6qu3:D, 6qu4:A, 6qu4:B, 6qu4:C, 6qu4:D, 6qu5:A, 6qu5:B, 6sy7:A, 6sy7:B, 6sy7:C, 6sy7:D, 6sy7:E, 6sy7:F, 6sy7:G, 6sy7:H
14 6qu3:A 464 187 0.0614 0.0970 0.2406 0.022 3f5m:A, 3f5m:B, 3f5m:C, 3f5m:D, 6qu3:B, 6qu3:C, 6qu3:D, 6qu4:A, 6qu4:B, 6qu4:C, 6qu4:D, 6qu5:A, 6qu5:B, 6sy7:A, 6sy7:B, 6sy7:C, 6sy7:D, 6sy7:E, 6sy7:F, 6sy7:G, 6sy7:H
15 1kzh:B 530 332 0.1064 0.1472 0.2349 1.21e-04
16 1kzh:B 530 235 0.0600 0.0830 0.1872 1.4
17 1kzh:B 530 105 0.0355 0.0491 0.2476 5.6
18 2f48:B 552 249 0.0832 0.1105 0.2450 1.75e-04 2f48:A, 1kzh:A
19 2f48:B 552 235 0.0600 0.0797 0.1872 1.5 2f48:A, 1kzh:A
20 2f48:B 552 105 0.0355 0.0471 0.2476 6.0 2f48:A, 1kzh:A
21 7k04:A 524 53 0.0218 0.0305 0.3019 0.89 6cfi:A, 7m2u:A, 2qsg:A, 2qsh:A, 6ubf:A, 6ug1:A, 6uin:A, 4yir:A
22 3ahc:A 802 67 0.0259 0.0237 0.2836 1.1 3ahd:A, 3ahe:A, 3ahf:A, 3ahg:A, 3ahh:A, 3ahi:A, 3ahj:A
23 9ftw:B 279 86 0.0314 0.0824 0.2674 3.2 9ftw:A
24 8io8:A 788 97 0.0341 0.0317 0.2577 5.8 8io8:B, 8io9:A, 8io9:B, 8io9:C, 8io9:D, 8io9:E, 8io9:F, 8io9:G, 8io9:H, 8io9:I, 8io9:J, 8io9:K, 8io9:L, 8ioa:A, 8ioa:B, 8ioe:A, 8ioe:B, 8ioe:C, 8ioe:D, 8ioe:E, 8ioe:F, 8ioe:G, 8ioe:H, 8ioe:I, 8ioe:J, 8ioe:K, 8ioe:L
25 1fp1:D 340 54 0.0246 0.0529 0.3333 6.7 1fpq:A
26 6x32:B 3798 80 0.0300 0.0058 0.2750 7.0 6x32:E, 6x32:H, 6x32:K
27 5j55:A 480 49 0.0205 0.0312 0.3061 7.1 5j53:A, 5j54:A, 7qr6:A, 7qr6:B, 7qr6:C

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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