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TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
SAFITFEGPEGSGKTTVINEVYHRLVKDYDVIMTREPGGVPTGEEIRKIVLEGNDMDIRTEAMLFAASRREHLVLKVIPA
LKEGKVVLCDRYIDSSLAYQGYARGIGVEEVRALNEFAINGLYPDLTIYLNVSAEVGRERIIKNSNRLDQEDLKFHEKVI
EGYQEIIHRFKSVNADQPLENVVEDTYQTIIKYLEK

The query sequence (length=196) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 4dwj:B 203 203 1.0000 0.9655 0.9655 1.26e-139 2ccg:A, 2ccg:B, 2ccj:A, 2ccj:B, 4dwj:A, 4dwj:C, 4dwj:D, 4dwj:F, 4dwj:G, 4dwj:H, 4eaq:A, 4eaq:B, 4gfd:A, 4gfd:B, 4gsy:A, 4gsy:B, 4hdc:A, 4hdc:B, 4hej:A, 4hlc:A, 4hlc:B, 4hld:A, 4hld:B, 4qg7:A, 4qg7:B, 4qga:A, 4qga:B, 4qgf:A, 4qgf:B, 4qgg:A, 4qgg:B, 4qgh:A, 4qgh:B, 4xwa:A, 4xwa:B
2 5h56:B 195 165 0.3724 0.3744 0.4424 1.59e-38 5h56:A, 5h5k:A, 5h5k:B, 4s2e:A, 4s2e:B, 4s35:A, 4s35:B, 5xai:B, 5xai:A, 5xb2:B, 5xb2:A, 5xb3:A, 5xb3:B, 5xb5:A
3 4edh:B 209 201 0.3878 0.3636 0.3781 3.57e-38 4e5u:A, 4e5u:B, 4edh:A, 4gmd:A, 4gmd:B, 4gmd:C, 4gmd:D, 3uwk:A, 3uwk:B, 3uwo:A, 3uwo:B, 3uxm:A, 3uxm:B, 3uxm:C, 3uxm:D
4 3hjn:A 189 162 0.4031 0.4180 0.4877 6.11e-38 3hjn:B
5 5x7j:B 197 187 0.3673 0.3655 0.3850 2.11e-33 5x7j:A, 5x86:B, 5x86:A, 5x8a:B, 5x8b:A, 5x8b:B, 5x8c:A, 5x8c:B, 5x8d:B, 5x8d:A, 5x98:B, 5x98:A, 5x99:A, 5x99:B, 5xal:A, 5xal:B, 5xt8:A, 5xt8:B, 5zax:A, 5zax:B, 5zb0:A, 5zb0:B, 5zb4:A, 5zb4:B
6 4tmk:A 210 208 0.3622 0.3381 0.3413 2.00e-29 5tmp:A
7 3lv8:A 204 205 0.3724 0.3578 0.3561 1.12e-27
8 5h70:B 207 145 0.2245 0.2126 0.3034 6.52e-11 5h70:A
9 2wwf:C 212 201 0.3010 0.2783 0.2935 1.94e-10 2wwf:A, 2wwf:B, 2wwg:A, 2wwg:B, 2wwg:C, 2wwh:A, 2wwh:B, 2wwh:C, 2wwi:A, 2wwi:B, 2wwi:C, 2yof:A, 2yof:B, 2yof:C, 2yog:A, 2yog:B, 2yoh:A, 2yoh:B
10 2v54:A 204 167 0.2398 0.2304 0.2814 9.50e-08 2v54:B, 2w0s:A, 2w0s:B
11 3tmk:A 216 179 0.2551 0.2315 0.2793 1.86e-07 1tmk:A, 1tmk:B, 2tmk:A, 2tmk:B, 3tmk:B, 3tmk:C, 3tmk:D, 3tmk:E, 3tmk:F, 3tmk:G, 3tmk:H
12 7fgq:A 190 200 0.2551 0.2632 0.2500 2.70e-04
13 5nrn:B 211 158 0.2398 0.2227 0.2975 0.001 1g3u:A, 1gsi:A, 1gtv:A, 1gtv:B, 1mrn:A, 1mrs:A, 1n5i:A, 1n5j:A, 1n5k:A, 1n5k:B, 1n5l:A, 1n5l:B, 5nrq:A, 1w2g:A, 1w2g:B, 1w2h:A, 1w2h:B, 6yt1:A, 6yt1:B
14 5uiv:A 225 100 0.1480 0.1289 0.2900 0.39
15 6ybh:D 219 161 0.2551 0.2283 0.3106 0.46 1j90:A, 1j90:B, 2jcs:A, 2jcs:B, 2jj8:A, 2jj8:B, 2jj8:C, 2jj8:D, 1oe0:A, 1oe0:B, 1oe0:C, 1oe0:D, 1ot3:A, 1ot3:B, 1ot3:C, 1ot3:D, 1ot3:E, 1ot3:F, 1ot3:G, 1ot3:H, 2vp0:A, 2vp0:B, 2vp2:A, 2vp2:B, 2vp4:A, 2vp4:B, 2vp4:C, 2vp4:D, 2vp5:A, 2vp5:B, 2vp6:A, 2vp6:B, 2vp6:C, 2vp6:D, 2vp6:E, 2vp6:F, 2vp6:G, 2vp6:H, 2vp9:A, 2vp9:B, 2vp9:C, 2vp9:D, 2vp9:E, 2vp9:F, 2vp9:G, 2vp9:H, 2vpp:A, 2vpp:B, 2vqs:A, 2vqs:B, 2vqs:C, 2vqs:D, 6ybh:A, 6ybh:B, 6ybh:C, 6ybh:E, 6ybh:F, 1zm7:A, 1zm7:B, 1zm7:C, 1zm7:D, 1zmx:A, 1zmx:B, 1zmx:C, 1zmx:D, 1zmx:E, 1zmx:F, 1zmx:G, 1zmx:H
16 4hi0:E 196 24 0.0612 0.0612 0.5000 0.83 4hi0:F
17 7yq0:A 173 25 0.0612 0.0694 0.4800 0.96 7yq0:B, 7yq1:A, 7yq1:B, 7yq1:C, 7yq1:D, 7yq1:E, 7yq1:F
18 8i3a:A 562 23 0.0612 0.0214 0.5217 1.2 8i39:A, 8i39:B, 8i3a:B, 8i3b:A, 8i3b:B, 8i3c:A, 8i3c:B, 8iwn:A, 8iwn:C, 8wam:A, 8wam:B, 8wba:A, 8wba:B
19 6quz:D 574 74 0.1224 0.0418 0.3243 1.3 6quz:B, 6qv0:B, 6qv0:D, 6qv1:B, 6qv1:D, 6qv2:B, 6qv2:D
20 1ko5:A 172 85 0.1429 0.1628 0.3294 1.4 1ko5:B, 1ko8:A, 1kof:A, 1kof:B
21 7d08:B 263 69 0.1020 0.0760 0.2899 1.5 7d08:E, 7d09:B, 7d09:E, 7d0a:B, 7d0a:E, 6z5u:K, 6z5u:L
22 8e2l:C 461 16 0.0612 0.0260 0.7500 1.6 8e2l:A, 8e2l:B, 8e2l:D, 8e2l:E, 8e2l:F
23 5nq5:A 191 141 0.2041 0.2094 0.2837 1.6 5nr7:A, 5nr7:B, 5nrn:A, 5nrq:B, 4unn:A, 4unn:B, 4unp:A, 4unq:A, 4unq:B, 4unr:A, 4unr:B, 4uns:A, 4uns:B
24 7jgr:D 441 21 0.0612 0.0272 0.5714 2.0 7jgs:D, 7jk2:D, 7jk3:D, 7jk4:D, 7jk5:D, 7jk6:D
25 8hr8:G 830 47 0.0867 0.0205 0.3617 2.8 8hr9:G, 8hr9:N
26 8hra:C 852 47 0.0867 0.0200 0.3617 2.9 8hr8:A, 8hr8:C, 8hr8:F, 8hr8:H, 8hr9:A, 8hr9:C, 8hr9:F, 8hr9:H, 8hr9:I, 8hr9:J, 8hr9:M, 8hr9:O, 8hra:D, 8hra:E, 8hra:H, 8hra:A, 8hra:B, 8hra:G, 8hrb:D, 8hrb:E, 8hrb:C, 8hrb:H, 8hrb:A, 8hrb:B, 8hrb:M, 8hrb:P, 8hrb:L, 8hrb:R, 8hrb:F, 8hrb:K, 8hrb:Q, 8hrb:G
27 8fcj:A 212 36 0.0612 0.0566 0.3333 2.9 8fcu:A, 8fd2:A, 8fd3:A, 8ff4:A, 8ff5:A
28 4nec:B 244 50 0.0816 0.0656 0.3200 3.3 4nec:A, 4nec:C, 4nec:D
29 2ccr:B 387 31 0.0663 0.0336 0.4194 3.6 2ccr:A, 2gft:A, 2gft:B, 2j74:A, 2j74:B, 1r8l:A, 1r8l:B, 1ur0:A, 1ur0:B, 1ur4:A, 1ur4:B
30 3cob:A 355 86 0.1071 0.0592 0.2442 3.7 3cob:C, 1sdm:A
31 4die:C 213 29 0.0510 0.0469 0.3448 3.8 4die:A, 4die:B, 4die:D
32 5xu1:B 226 19 0.0459 0.0398 0.4737 4.0 5xu1:A
33 5e9f:B 501 51 0.0816 0.0319 0.3137 4.6 5e9f:C, 5e9g:C
34 5e9g:D 486 51 0.0816 0.0329 0.3137 4.9
35 5e9g:B 525 51 0.0816 0.0305 0.3137 4.9 5e9f:A, 5e9g:A
36 1f3o:A 232 17 0.0459 0.0388 0.5294 4.9 1l2t:A, 1l2t:B, 3tif:A, 3tif:B
37 5e9f:D 453 51 0.0816 0.0353 0.3137 5.0
38 8wpe:A 1006 37 0.0765 0.0149 0.4054 5.2 8hg1:A, 8hpa:A, 8j86:A, 8j8f:A, 8j8g:A, 8k8s:A, 8k8u:A, 5n2g:A, 8wpf:A, 8wpk:A, 8wpp:A
39 8tn6:A 147 46 0.0816 0.1088 0.3478 5.7 8tn6:B, 8tn6:C, 8tnb:A, 8tnb:B, 8tnb:C, 8tnc:A, 8tnc:B, 8tnc:C, 8tnd:A, 8tnd:B, 8tnd:C
40 3ux8:A 564 24 0.0510 0.0177 0.4167 6.2
41 2r6f:A 899 24 0.0510 0.0111 0.4167 6.7
42 3uwx:A 945 24 0.0510 0.0106 0.4167 6.8
43 2r6f:B 879 24 0.0510 0.0114 0.4167 6.8
44 8faz:X 236 37 0.0663 0.0551 0.3514 7.0 8gbj:X, 8ouy:D, 8ouz:D
45 2ewv:A 343 38 0.0714 0.0408 0.3684 7.7 2eww:A, 2gsz:F
46 7d4i:RJ 738 21 0.0510 0.0136 0.4762 7.7 7d5t:RJ, 6lqs:RJ, 6lqt:RJ
47 7suk:SI 802 21 0.0510 0.0125 0.4762 8.3 7d63:RJ, 6ke6:RJ, 6lqp:RJ, 6lqq:RJ, 6lqr:RJ, 6lqu:RJ, 6lqv:RJ, 5wlc:SI
48 5evy:X 411 68 0.1020 0.0487 0.2941 8.3
49 7wtl:CL 610 21 0.0510 0.0164 0.4762 8.4 5wyj:B1, 5wyk:B1
50 7ajt:CL 781 21 0.0510 0.0128 0.4762 8.4 7d5s:RJ, 6zqa:CL, 6zqb:CL, 6zqc:CL
51 7aju:CL 808 20 0.0510 0.0124 0.5000 8.6 6zqd:CL, 6zqe:CL, 6zqf:CL, 6zqg:CL
52 2y7h:B 529 81 0.1071 0.0397 0.2593 8.8 2y7h:C
53 8ipr:A 504 18 0.0510 0.0198 0.5556 9.9 8ipr:D

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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