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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
SAAIGLFYGTQTGKTESVAEIIRDEFGNDVVTLHDVSQAEVTDLNDYQYLIIGCPTWNIGELQSDWEGLYSELDDVDFNG
KLVAYFGTGDQIGYADNFQDAIGILEEKISQRGGKTVGYWSTDGYDFNDSKALRNGKFVGLALDEDNQSDLTDDRIKSWV
AQLKSEFGL

The query sequence (length=169) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 3esx:B 169 169 0.9645 0.9645 0.9645 1.57e-117 3esx:A, 3esy:A, 3esy:B, 3esy:C, 3esy:D, 3esz:A, 3esz:B, 1flv:A, 5ljp:A, 1obo:A, 1obo:B, 1obv:A, 1rcf:A, 2v5u:A, 2v5u:B, 2v5v:A, 2v5v:B
2 1czh:A 169 169 0.6923 0.6923 0.6923 1.61e-85 1czk:A, 1czl:A, 1czn:A, 1czo:A, 1czr:A, 1czu:A, 1d03:A, 1d04:A, 6kif:P, 6kif:X, 6kif:p, 1ofv:A
3 2mt9:A 173 167 0.4852 0.4740 0.4910 2.45e-54
4 2mok:A 176 169 0.4615 0.4432 0.4615 5.97e-53 1ag9:A, 1ag9:B, 1ahn:A
5 5k9b:A 179 177 0.4911 0.4637 0.4689 4.51e-51 1yob:A, 1yob:B
6 2wc1:A 182 177 0.4379 0.4066 0.4181 7.08e-44
7 8snz:A 167 161 0.4083 0.4132 0.4286 4.34e-42 8snz:B, 8v2y:A
8 2bmv:A 163 164 0.4379 0.4540 0.4512 2.17e-41 1fue:A, 2w5u:A, 2w5u:B
9 2fcr:A 173 174 0.4201 0.4104 0.4080 2.24e-33
10 6ohk:A 170 165 0.3609 0.3588 0.3697 5.30e-31 6ohl:A
11 8v2y:B 151 161 0.3550 0.3974 0.3727 7.14e-26
12 6gaq:A 146 119 0.2544 0.2945 0.3613 2.57e-15 6gaq:B
13 3f6r:A 147 136 0.2367 0.2721 0.2941 3.33e-12 3f6r:B, 3f6r:C, 3f6r:D, 3f6s:A, 3f6s:G, 3f6s:B, 3f6s:D, 3f6s:E, 3f6s:F, 3f6s:H, 3f6s:I, 3f90:A, 3f90:B, 3f90:D, 3f90:E, 3f90:F, 3f90:H, 3f90:I, 3f90:G
14 3kap:A 147 117 0.2130 0.2449 0.3077 8.44e-12 3kaq:A
15 6fsg:A 147 116 0.2130 0.2449 0.3103 4.12e-10 6fsi:A, 6ft1:A
16 4heq:A 145 118 0.2367 0.2759 0.3390 1.64e-09 4heq:B
17 5v57:A 645 145 0.2781 0.0729 0.3241 3.18e-09 1akq:A, 1akr:A, 1akt:A, 1aku:A, 1akv:A, 1akw:A, 1azl:A, 1bu5:A, 1bu5:B, 1c7e:A, 1c7e:B, 1c7f:A, 1c7f:B, 1f4p:A, 1fx1:A, 2fx2:A, 3fx2:A, 4fx2:A, 5fx2:A, 1i1o:A, 1j8q:A, 1j9e:A, 1j9g:A, 5v56:A, 5v56:B, 5v57:B, 1wsb:A, 1wsw:A, 1xt6:A, 1xyv:A, 1xyy:A, 5yob:A, 5yoc:A, 5yoe:A, 5yog:A
18 7k15:A 455 117 0.2249 0.0835 0.3248 2.75e-07
19 7epe:A 389 117 0.2249 0.0977 0.3248 2.75e-07 7epf:A
20 5tgz:A 439 117 0.2249 0.0866 0.3248 3.36e-07 7v3z:A, 5xr8:A, 5xra:A
21 7ddz:A 437 117 0.2249 0.0870 0.3248 5.09e-07
22 5zkp:A 436 117 0.2249 0.0872 0.3248 8.18e-07
23 6li0:A 441 117 0.2249 0.0862 0.3248 9.55e-07 6li1:A
24 5veg:B 149 113 0.1834 0.2081 0.2743 1.21e-06 5veg:A, 5veg:C
25 5lji:A 145 103 0.1834 0.2138 0.3010 5.46e-06 5lji:C
26 2fax:A 138 87 0.1775 0.2174 0.3448 0.004 2fdx:A, 1fla:A, 1fld:A, 1fln:A, 2flv:A, 2fox:A, 1fvx:A, 2fvx:A, 3nll:A, 4nll:A, 5nll:A, 4nul:A, 5nul:A, 6nul:A, 5ull:A
27 6j79:A 816 124 0.1775 0.0368 0.2419 0.30 1amo:A, 1amo:B, 1b1c:A, 1dve:A, 1dvg:A, 1dvg:B, 2dy5:A, 2e7e:A, 5emn:A, 5emn:B, 3es9:A, 3es9:B, 3es9:C, 5fa6:A, 5fa6:B, 4g7l:A, 4g7p:A, 4g7t:A, 4g7u:A, 4g8p:A, 4g8u:A, 4g8w:A, 4g98:A, 4g99:A, 3i9t:A, 3i9u:A, 1ivj:A, 1ix3:A, 1ix4:A, 1j02:A, 1j2c:A, 6j79:B, 6j7a:A, 6j7a:B, 6j7i:A, 6j7i:B, 1j9z:A, 1j9z:B, 1ja0:A, 1ja0:B, 1ja1:A, 1ja1:B, 7l18:AAA, 7l18:BBB, 4mec:A, 4mec:B, 4mec:C, 4mec:D, 4mec:E, 6njr:A, 6njr:B, 3ojw:A, 3ojx:A, 3qe2:A, 3qe2:B, 3qfc:A, 3qfc:B, 3qfr:A, 3qfr:B, 1ubb:A, 1ulx:A, 5urd:A, 5urd:B, 5ure:A, 5ure:B, 5urg:A, 5urg:B, 5urh:A, 5urh:B, 5uri:A, 5uri:B, 1vgi:A, 3wkt:A, 3wkt:B, 3wkt:C, 3wkt:D, 4y7c:A, 4y7c:B, 4y9r:A, 4y9r:B, 4y9u:A, 4y9u:B, 4yaf:A, 4yaf:B, 4yal:A, 4yal:B, 4yao:A, 4yao:B, 4yau:A, 4yau:B, 4yaw:A, 4yaw:B, 2zvu:A
28 4p7m:A 104 72 0.1361 0.2212 0.3194 0.40 4p7s:A, 4p7s:B, 4p7s:C
29 3nyc:A 381 79 0.1538 0.0682 0.3291 1.2 3nye:A, 3nyf:A, 6p9d:A, 6pld:A, 7rdf:A, 3sm8:A
30 4oxx:A 153 118 0.1834 0.2026 0.2627 1.4
31 4s0m:D 143 30 0.0710 0.0839 0.4000 1.7 5yol:E, 5yol:H
32 4a2i:P 82 62 0.0947 0.1951 0.2581 2.9 8a3l:P, 7abz:u, 7ac7:u, 7acj:u, 7acr:u, 4adv:P, 5afi:p, 7afi:P, 7afl:P, 7afo:P, 8akn:Q, 8am9:Q, 6awb:S, 6awc:S, 6awd:S, 9ax7:P, 9ax8:p, 8aye:P, 8b0x:P, 7b5k:p, 8b7y:u, 8bf7:t, 8bge:t, 8bgh:t, 8bh4:t, 8bhj:t, 8bhl:t, 8bhn:t, 8bhp:t, 8bil:t, 8bim:t, 7bod:P, 7boe:P, 7bof:P, 7bog:P, 7boh:P, 7boi:P, 6bu8:P, 6by1:AP, 6by1:BP, 6c4i:p, 8cai:P, 8cep:P, 8cgj:P, 8cgr:P, 8cgu:P, 9cg5:P, 9cg6:P, 9cg7:P, 7cpj:p, 7d6z:w, 7d80:Q, 6dnc:CB, 8eiu:P, 8ekc:p, 8emm:P, 6enf:p, 6enj:p, 6enu:p, 8eyq:P, 8eyt:P, 9fbv:P, 8fiz:AO, 8fto:P, 8fzd:p, 8fze:p, 8fzf:p, 8fzg:p, 8fzh:p, 8fzi:p, 8fzj:p, 8g2u:o, 8g31:o, 8g34:o, 8g38:o, 8g6w:P, 8g7p:p, 8g7q:p, 8g7r:p, 8g7s:p, 8ghu:p, 6gwt:p, 6gxm:p, 6gxn:p, 6gxo:p, 6gxp:p, 6h4n:p, 5h5u:w, 6h58:p, 6h58:pp, 6hrm:u, 8hsp:P, 8htz:P, 8hu1:P, 6i7v:AP, 6i7v:BP, 8ifb:P, 8ifc:P, 5iqr:u, 5it8:AP, 5it8:BP, 5j5b:AP, 5j5b:BP, 5j7l:AP, 5j7l:BP, 5j88:AP, 5j88:BP, 5j8a:AP, 5j8a:BP, 3j9y:p, 3j9z:SP, 5j91:AP, 5j91:BP, 3ja1:SP, 3jbu:P, 3jbv:P, 3jcd:p, 3jce:p, 3jcj:y, 3jcn:s, 5jc9:AP, 5jc9:BP, 7jss:U, 7jsw:U, 7jsz:U, 8jsg:y, 8jsh:y, 5jte:AP, 7jt1:U, 7jt2:U, 7jt3:U, 5ju8:AP, 7k00:P, 8k3o:P, 8k4e:P, 7k50:U, 7k51:U, 7k52:U, 7k53:U, 7k54:U, 7k55:U, 5kcr:1p, 5kcs:1p, 5kps:21, 5kpv:20, 5kpw:20, 5kpx:20, 5l3p:p, 6lkq:O, 7lv0:U, 5lza:p, 5lzb:p, 5lzc:p, 5lzd:p, 5lze:p, 5lzf:p, 7m5d:u, 5mdv:u, 5mdw:u, 5mdy:u, 5mdz:u, 5me0:P, 5me1:P, 5mgp:p, 5my1:P, 7n1p:SP, 7n2c:SP, 7n2u:SP, 7n2v:SP, 7n30:SP, 7n31:SP, 7nar:P, 7nas:P, 7nat:P, 7nau:P, 7nav:P, 7nax:P, 7nbu:P, 5no2:P, 5no3:P, 5no4:P, 5np6:S, 6nqb:P, 7nso:p, 7nsp:p, 7nsq:p, 5nwy:F, 7nwt:u, 7nww:t, 7o19:AP, 7o1a:AP, 7o1c:AP, 5o2r:p, 7o5h:P, 6o7k:y, 6o9j:p, 6o9k:p, 7oe0:P, 7oe1:P, 6ofx:U, 6og7:U, 6ogf:U, 6ogg:U, 6ogi:U, 7oi0:P, 7oif:t, 7oig:t, 7oii:t, 7oiz:P, 7oj0:P, 6om6:u, 6ore:u, 6orl:u, 6osk:u, 6osq:u, 6ost:u, 6ot3:u, 7ot5:t, 7otc:p, 6ouo:u, 8p16:u, 8p17:u, 8p18:u, 7p3k:P, 8peg:P, 8phj:P, 7pjs:p, 7pjt:p, 7pju:p, 7pjv:p, 7pjw:p, 7pjx:p, 7pjy:p, 7pjz:p, 8pkl:P, 8pva:P, 7q4k:AP, 8q4f:P, 6q97:u, 6q98:u, 6q9a:u, 7qg8:I, 7qgh:G, 7qgn:I, 7qgr:G, 8qk7:u, 8qoa:P, 8r3v:P1, 8r6c:P, 8r8m:P, 8rcl:P1, 8rcm:P1, 8rcs:P1, 8rct:P1, 7s1g:x, 7s1h:x, 7s1i:x, 7s1j:x, 7s1k:x, 7sa4:u, 7ss9:U, 7ssd:U, 7ssl:U, 7ssn:U, 7sso:U, 7ssw:U, 7st2:U, 7st6:U, 7st7:U, 8syl:p, 6szs:p, 8t5d:o, 8t5h:o, 6tbv:S161, 6tc3:S161, 7tos:S16, 4u1u:AP, 4u1u:CP, 4u1v:AP, 4u1v:CP, 4u20:AP, 4u20:CP, 4u24:AP, 4u24:CP, 4u25:AP, 4u25:CP, 4u26:AP, 4u26:CP, 4u27:AP, 4u27:CP, 5u4i:p, 5u9f:P, 5u9g:P, 7ug7:SP, 7uph:C, 8upo:U, 8upr:U, 8uql:U, 8uqm:U, 8uqp:U, 8ur0:U, 8urh:U, 8uri:U, 8urx:U, 8ury:U, 5uyk:P, 5uyl:P, 5uym:P, 5uyn:P, 5uyp:P, 5uyq:P, 5uz4:P, 4v4h:AP, 4v4h:CP, 4v4q:AP, 4v4q:CP, 4v4v:AP, 4v4w:AP, 4v50:AP, 4v50:CP, 4v52:AP, 4v52:CP, 4v53:AP, 4v53:CP, 4v54:AP, 4v54:CP, 4v55:AP, 4v55:CP, 4v56:AP, 4v56:CP, 4v57:AP, 4v57:CP, 4v5b:BP, 4v5b:DP, 4v5h:AP, 4v5y:AP, 4v5y:CP, 4v64:AP, 4v64:CP, 4v65:AI, 4v66:AI, 4v69:AP, 4v6c:AP, 4v6c:CP, 4v6d:AP, 4v6d:CP, 4v6e:AP, 4v6e:CP, 4v6k:BT, 4v6l:AT, 4v6m:AP, 4v6n:BS, 4v6o:AS, 4v6p:AS, 4v6q:AS, 4v6r:AS, 4v6s:BR, 4v6t:AP, 4v6v:AP, 4v6y:AP, 4v6z:AP, 4v70:AP, 4v71:AP, 4v72:AP, 4v73:AP, 4v74:AP, 4v75:AP, 4v76:AP, 4v77:AP, 4v78:AP, 4v79:AP, 4v7a:AP, 4v7b:AP, 4v7c:AP, 4v7d:BP, 4v7i:BP, 4v7s:AP, 4v7s:CP, 4v7t:AP, 4v7t:CP, 4v7u:AP, 4v7u:CP, 4v7v:AP, 4v7v:CP, 4v85:AP, 4v89:AP, 4v9c:AP, 4v9c:CP, 4v9d:AP, 4v9d:BP, 4v9o:BP, 4v9o:DP, 4v9o:FP, 4v9o:HP, 4v9p:BP, 4v9p:DP, 4v9p:FP, 4v9p:HP, 8vs9:S16, 8vsa:S16, 6vu3:U, 6vwl:o, 6vwm:o, 6vwn:o, 6vyq:U, 6vyr:U, 6vys:U, 6vyt:U, 6vyu:U, 6vyw:U, 6vyx:U, 6vyy:U, 6vyz:U, 6vz2:U, 6vz3:U, 6vz5:U, 6vz7:U, 6vzj:U, 6w6k:P, 6w77:P, 6w7m:P, 6w7n:P, 6w7w:O, 5wdt:p, 6wd0:U, 6wd1:U, 6wd2:U, 6wd3:U, 6wd4:U, 6wd5:U, 6wd6:U, 6wd7:U, 6wd8:U, 6wd9:U, 6wda:U, 6wdb:U, 6wdc:U, 6wdd:U, 6wde:U, 6wdf:U, 6wdg:U, 6wdh:U, 6wdi:U, 6wdj:U, 6wdk:U, 6wdl:U, 6wdm:U, 5we4:p, 5we6:p, 4wf1:AP, 4wf1:CP, 5wf0:p, 5wfk:p, 5wfs:p, 6wnv:U, 6wnw:U, 4woi:AP, 4woi:DP, 4www:QP, 4www:XP, 6x6t:U, 6x7f:U, 6x7k:U, 6x9q:U, 6xdq:U, 6xdr:U, 6xe0:P, 6xgf:U, 6xii:U, 6xij:U, 6xza:P1, 6xzb:P1, 6y69:p, 7y7c:P, 7y7d:P, 7y7e:P, 7y7f:P, 7y7g:P, 7y7h:P, 4ybb:AP, 4ybb:BP, 2ykr:P, 6ysr:p, 6yss:p, 6yst:p, 6ysu:p, 6ztj:AP, 6ztl:AP, 6ztm:AP, 6ztn:AP, 6zto:AP, 6ztp:AP, 7zta:S161, 6zu1:AP
33 1bda:A 265 53 0.0888 0.0566 0.2830 2.9 1a5h:A, 1a5h:B, 1bda:B, 1rtf:B
34 2m6s:A 149 125 0.1893 0.2148 0.2560 3.3
35 5tth:B 621 49 0.0888 0.0242 0.3061 4.0 6d14:B, 7exp:B, 4ipe:B, 4iyn:B, 4j0b:B, 5tvu:B, 5tvw:B, 5tvx:B
36 3tcs:B 367 79 0.1183 0.0545 0.2532 4.2 3tcs:A
37 5tth:A 671 59 0.0888 0.0224 0.2542 4.5 6d14:A, 7exp:A, 4ipe:A, 4ivg:A, 4iyn:A, 4j0b:A, 4mli:A, 4mli:C, 4mls:A, 5tvu:A, 5tvw:A, 5tvx:A
38 3j6q:A 1058 52 0.1065 0.0170 0.3462 4.6 3j6q:B, 3j6q:C, 3j6q:D, 3j6q:E, 3jay:A, 3jb0:A, 3jb1:A, 3jb2:A, 3jb3:A, 7whp:A, 7whp:B
39 7oui:S 216 35 0.0769 0.0602 0.3714 5.3 3jcu:S, 3jcu:s, 5mdx:S, 5mdx:s, 7oui:s
40 2c9o:A 398 52 0.1006 0.0427 0.3269 5.7 2c9o:B
41 4eso:B 251 39 0.0888 0.0598 0.3846 7.6 4eso:A, 4eso:C, 4eso:D
42 3wev:B 681 87 0.1361 0.0338 0.2644 8.1 3wev:A
43 5fm6:A 426 47 0.1006 0.0399 0.3617 9.2 5fm7:A, 4ww4:A
44 8g8v:A 254 48 0.0947 0.0630 0.3333 9.3 8g6c:A, 8g6c:B, 8g8v:B, 8tcc:A, 8tcc:B, 8tcc:C, 8tcc:D
45 8a0c:A 1116 54 0.0769 0.0116 0.2407 9.5 8a0c:B, 8a0m:A, 8a0m:C

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218