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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
RYSLRQDIAVEPVIAGWYGWSYLLPPQTLARFVHNRFNRIVESYLDDPQVHAAAVRQRRMHGGPWIHAHEHRDAIEAWYR
ETAPRRERLDELFEAVRRLEEDILPRHHGECLDPVYQELPAALAGRVEVFYGRDNRTADYRFVEPLMYASEYYDESWQQV
RFRPVTEDAREFALTTPMLEYGPEQLLVNVPLNSPLLDAVFRGGLTGTELDDLAARFGLDGERAARFASYFEPTPEDVLE
YVGHACVFARHRGTTFLVDPVLSYSGYPGGAENRFTFADLPERIDHLLITHNHQDHMLFETLLRIRHRVGRVLVPKSTNA
SLVDPGLGGILRRLGFTDVVEVDDLETLSCGSAEVVALPFLGDHGDLRIRSKTGWLIRFGERSVLFAADSTNISPTMYTK
VAEVIGPVDTVFIGMESIGAAASWIYGPLYGEPLDRRTDQSRRLNGSNFPQAREIVDALEPDEVYVYAMGLEPWMGVVMP
AIVDSDLLVRHVQDKGGTAERLHLRRTLRL

The query sequence (length=510) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 4jo0:A 522 519 0.9980 0.9751 0.9807 0.0 5kik:A, 5kil:A
2 8a90:B 530 527 0.3490 0.3358 0.3378 9.38e-94 8a90:A
3 8p90:B 334 205 0.1039 0.1587 0.2585 2.20e-08 8p90:A, 8p96:A, 8p96:B, 8pc4:A, 8pc4:B, 4qn9:A, 4qn9:B
4 7t28:A 238 86 0.0647 0.1387 0.3837 0.001
5 3rpc:A 262 212 0.1059 0.2061 0.2547 0.023 3rpc:B, 3rpc:C, 3rpc:D
6 6brm:B 263 215 0.0980 0.1901 0.2326 0.034 6brm:A, 6brm:C, 6brm:D, 6brm:E, 6brm:F, 6brm:G, 6brm:H
7 7fct:B 239 167 0.0725 0.1548 0.2216 0.076 7fct:A
8 2ycb:B 635 62 0.0353 0.0283 0.2903 0.20 2ycb:A
9 3wqy:A 905 55 0.0373 0.0210 0.3455 0.30 3wqy:B, 3wqz:A, 3wqz:B, 2ztg:A
10 2vou:A 393 109 0.0627 0.0814 0.2936 0.40 2vou:B, 2vou:C
11 2i7t:A 404 167 0.0863 0.1089 0.2635 1.7
12 3kl7:A 220 60 0.0333 0.0773 0.2833 2.4
13 4o98:B 307 103 0.0608 0.1010 0.3010 2.4 4o98:A
14 5zb3:A 280 37 0.0294 0.0536 0.4054 2.5 5zb1:A, 5zb3:B
15 6i1d:A 458 82 0.0490 0.0546 0.3049 2.6
16 2i7v:A 433 154 0.0745 0.0878 0.2468 3.0 8t1q:A, 8t1r:A
17 4le6:A 257 103 0.0608 0.1206 0.3010 3.5 4le6:B, 4le6:C, 4le6:D, 4le6:E
18 6bcq:B 983 62 0.0490 0.0254 0.4032 3.8 6bco:B, 6bco:D, 6bco:A, 6bco:C, 6bcq:D, 6bcq:A, 6bcq:C
19 7f0y:A 141 63 0.0373 0.1348 0.3016 4.1 7f0y:B, 7f10:B, 7f11:B
20 8qby:G 666 81 0.0549 0.0420 0.3457 4.2
21 3x2x:A 227 59 0.0333 0.0749 0.2881 5.1 3x2x:B, 3x30:A
22 6v4x:H 499 58 0.0373 0.0381 0.3276 5.2 6m8q:A, 6m8q:B
23 3csk:A 710 56 0.0333 0.0239 0.3036 6.6
24 7u2s:A 248 47 0.0353 0.0726 0.3830 7.0 7u2s:B
25 6q55:A 461 57 0.0392 0.0434 0.3509 9.5 6q5a:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218