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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
RVVGVVVPLIHTNFADEIIKGLYETTISSGYELLITYLDEDEDHQYQVFQTLLSRQVGAVFMLSLDIPSWMIDKLLEEQI
SVISLTALLSEQISAVTSNEFEMMNSIVDYLIDMGHKNIALVGDTKLTTNISSTRRTNFIKSMTDHNLAYENIFLYGNDH
SYETGYTSVTTGYDINQLPFTAAIATADMVGQGLINAMSDHGKTVPEDLSIVTIDGLQQTEIARPKLTTVKQDFPEIGRI
AMQLFLDSDEPQIIYIPTELIQRDSVLNLN

The query sequence (length=270) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 4rk6:A 270 270 1.0000 1.0000 1.0000 0.0 4rk6:B, 4rk7:A, 4rk7:B
2 1rzr:G 332 245 0.2481 0.2018 0.2735 6.24e-27 2jcg:A, 2nzu:G, 2nzv:G, 1rzr:C, 1rzr:A, 1rzr:D, 1sxg:B, 1zvv:A, 1zvv:B, 1zvv:G
3 3oqo:A 333 270 0.2519 0.2042 0.2519 1.22e-24 3oqm:A, 3oqm:C, 3oqn:A, 3oqn:C, 3oqo:C
4 3k4h:A 282 280 0.2815 0.2695 0.2714 2.29e-22 3k4h:B
5 1jft:A 340 274 0.2407 0.1912 0.2372 2.07e-19 1bdh:A, 1bdi:A, 1jfs:A, 1jh9:A, 1pnr:A, 2pua:A, 2pub:A, 2puc:A, 2pud:A, 2pue:A, 2puf:A, 2pug:A, 1qp0:A, 1qp4:A, 1qp7:A, 1qpz:A, 1qqa:A, 1qqb:A, 1vpw:A, 1wet:A, 1zay:A
6 2o20:B 275 245 0.2259 0.2218 0.2490 2.93e-17 2o20:A, 2o20:F, 2o20:G
7 4rk0:D 269 277 0.2556 0.2565 0.2491 9.07e-16 4rk0:A, 4rk0:B, 4rk0:C
8 4rk1:D 269 249 0.2296 0.2305 0.2490 2.54e-15 4rk1:A, 4rk1:B, 4rk1:C, 4rk1:E, 4rk1:F
9 4rk5:A 275 240 0.2074 0.2036 0.2333 3.14e-11 4rk4:A
10 5ysz:A 327 267 0.2259 0.1865 0.2285 7.37e-10
11 1lbg:A 357 167 0.1593 0.1204 0.2575 6.47e-09 2bjc:A, 2bjc:B, 1cjg:A, 1cjg:B, 1efa:A, 1efa:B, 1efa:C, 1jwl:B, 1jwl:A, 1jwl:C, 2kei:A, 2kei:B, 2kej:A, 2kej:B, 2kek:A, 2kek:B, 1l1m:A, 1l1m:B, 1lbg:D, 1lbh:A, 1lbh:B, 1lbh:C, 1lbh:D, 1lcc:A, 1lcd:A, 1osl:A, 1osl:B, 2p9h:A, 2p9h:B, 2paf:A, 2paf:B, 2pe5:A, 2pe5:B, 2pe5:C, 4rzt:A, 4rzt:B, 4rzt:C, 4rzt:D, 1tlf:A, 1tlf:B, 1tlf:C, 1tlf:D
12 4rkr:A 274 63 0.0815 0.0803 0.3492 1.46e-08 4rkr:B, 4rkr:C, 4rkr:D
13 7x7h:A 267 202 0.1963 0.1985 0.2624 1.65e-07 7x7h:C
14 8jff:A 274 255 0.2000 0.1971 0.2118 5.29e-07 8jff:B, 8jfv:A, 8jfv:B
15 3tb6:A 283 286 0.2444 0.2332 0.2308 6.10e-07 3tb6:B
16 3o75:A 270 147 0.1296 0.1296 0.2381 2.94e-06 3o75:B
17 3ctp:A 266 250 0.1630 0.1654 0.1760 1.66e-05 3ctp:B
18 3gyb:A 261 181 0.1815 0.1877 0.2707 1.51e-04 3gyb:B
19 4xxh:A 255 192 0.1519 0.1608 0.2135 0.81 4xxh:B
20 4iqy:A 221 80 0.0815 0.0995 0.2750 1.3 4iqy:B
21 2civ:A 299 48 0.0556 0.0502 0.3125 2.1 2ciw:A, 2cix:A, 2ciy:A, 2ciz:A, 2cj0:A, 2cj1:A, 2cj2:A, 1cpo:A, 2cpo:A, 2j18:A, 2j19:A, 2j5m:A, 7rst:A
22 6bdo:D 395 45 0.0630 0.0430 0.3778 3.2 6bdo:B, 6bdo:A, 6bdo:C, 5kmp:A, 5kmp:B, 5kmq:A, 5kmq:B, 5kmq:C, 5kmq:D, 5kmr:B, 5kmr:A, 5kmr:C, 5kmr:D, 5kms:A, 5kms:B, 5kms:C, 5kms:D, 4nwz:A, 4nwz:B, 4nwz:C, 4nwz:D, 5wed:B, 5wed:A, 5wed:C, 5wed:D
23 2z06:A 252 46 0.0667 0.0714 0.3913 8.2 2z06:B, 2z06:C, 2z06:D

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218