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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
RRTVSFNARVARNKSQAKKILEKADEFFARSVTMQYKAFACPNGVYDIQCTEGTVKGAAYEKRAMAVSAAFRAKQASPAA
KARALFENRRHAIIASHECQHEEDLFVRFPKLSAAYMMGKTEAMRTCSRYVVPDSLEEEYMAASVDRQMKERACPGGVYA
SSCVEGNAKGQAEQARVAALATAFRSAQKSASKTTAERYSSAAYGRDHFAHGCSYEESVFNTYPATAAAMRSKSYNY

The query sequence (length=237) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 7ezx:A1 257 237 1.0000 0.9222 1.0000 6.04e-176 7ezx:A7, 7ezx:A9, 7ezx:AF, 7ezx:AI, 7ezx:AK, 6kgx:A2, 6kgx:Y3, 6kgx:A6, 6kgx:A7, 6kgx:A9, 6kgx:AB, 6kgx:YD, 6kgx:AF, 6kgx:AI, 6kgx:AJ, 7y4l:AB, 7y4l:AC, 7y4l:AD, 7y4l:AE, 7y4l:AJ, 7y4l:YK, 7y4l:Y1, 7y4l:A2, 7y4l:A5, 7y4l:A6, 7y5e:YA, 7y5e:AD, 7y5e:AE, 7y5e:AG, 7y5e:AH, 7y5e:AO, 7y5e:AQ, 7y5e:A1, 7y5e:A4, 7y5e:Y7, 7y7a:A1, 7y7a:A2, 7y7a:A4, 7y7a:Y5, 7y7a:A8, 7y7a:YD, 7y7a:AF, 7y7a:AI, 7y7a:AK, 7y7a:AM, 7y7a:AP, 7y7a:AR, 7y7a:AS, 7y7a:Ac, 7y7a:Ae, 7y7a:Yg, 7y7a:Yi, 7y7a:Aj, 7y7a:Al, 7y7a:An
2 7ezx:AB 238 232 0.6329 0.6303 0.6466 1.87e-99 7ezx:wJ, 7ezx:xJ, 7ezx:wL, 7ezx:xL, 7ezx:AM, 6kgx:A8, 6kgx:AA, 6kgx:wE, 6kgx:xE, 6kgx:wG, 6kgx:xG, 7y4l:wF, 7y4l:AH, 7y4l:A4, 7y4l:w8, 7y4l:x8, 7y4l:xF, 7y5e:wF, 7y5e:AJ, 7y5e:wK, 7y5e:AM, 7y5e:xF, 7y5e:xK, 7y7a:A3, 7y7a:w6, 7y7a:x6, 7y7a:AC, 7y7a:wQ, 7y7a:xQ, 7y7a:wT, 7y7a:xT, 7y7a:AV, 7y7a:wb, 7y7a:xb, 7y7a:Ap
3 7ezx:BB 250 233 0.5781 0.5480 0.5880 5.83e-85 7ezx:yJ, 7ezx:yL, 7ezx:BM, 6kgx:B8, 6kgx:BA, 6kgx:yE, 6kgx:yG, 7y4l:yF, 7y4l:BH, 7y4l:B4, 7y4l:y8, 7y5e:yF, 7y5e:BJ, 7y5e:yK, 7y5e:BM, 7y7a:B3, 7y7a:y6, 7y7a:BC, 7y7a:yQ, 7y7a:yT, 7y7a:BV, 7y7a:yb, 7y7a:Bp
4 5y6p:lz 251 216 0.4430 0.4183 0.4861 6.75e-65 5y6p:ly, 5y6p:hY, 5y6p:hZ
5 5y6p:C2 245 218 0.4599 0.4449 0.5000 6.27e-64 5y6p:D2, 5y6p:c3, 5y6p:d3, 5y6p:44, 5y6p:Z5, 5y6p:e8, 5y6p:c8, 5y6p:d8, 5y6p:e9, 5y6p:c9, 5y6p:d9, 5y6p:T8, 5y6p:Y9, 5y6p:aZ, 5y6p:bZ
6 7y4l:MI 275 216 0.3797 0.3273 0.4167 1.87e-50 7ezx:MA, 7ezx:MG, 7ezx:MN, 7ezx:MQ, 6kgx:M1, 6kgx:21, 6kgx:M4, 6kgx:24, 7y4l:ZI, 7y4l:M9, 7y4l:Z9, 7y5e:Z9, 7y5e:M5, 7y5e:Z5, 7y5e:M9, 7y7a:MH, 7y7a:ZH, 7y7a:Ma, 7y7a:Mf, 7y7a:Za, 7y7a:Zf, 7y7a:Mh, 7y7a:Zh
7 5y6p:A2 277 215 0.3629 0.3105 0.4000 2.13e-43 5y6p:a3, 5y6p:34, 5y6p:Y5, 5y6p:b8, 5y6p:b9, 5y6p:U8, 5y6p:Z9, 5y6p:aY, 5y6p:bY, 5y6p:dw, 5y6p:dx, 5y6p:ey, 5y6p:ez
8 5y6p:eZ 309 210 0.3755 0.2880 0.4238 3.50e-40 5y6p:eY
9 5y6p:eZ 309 98 0.1392 0.1068 0.3367 0.045 5y6p:eY
10 5y6p:gy 260 208 0.2954 0.2692 0.3365 7.29e-39 5y6p:gz
11 2r4v:A 226 47 0.0591 0.0619 0.2979 0.63 2per:A
12 7fbq:A 234 34 0.0549 0.0556 0.3824 7.4 1k0n:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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