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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
RRLPFSFANRFKMVLEVEPPVLYYVEPLNAQALVEVRRVLKQTFVPQAIAAEAFEKKLTEAYQDFFSLAEEAPIIKLINA
MLGEAIKEGASDIHIETFEKILSIRFRVDGVLRDVLSPSRKLAPLLVSRVKVMAKLDIAEKRVPQDGRISLAVDVRVSTM
PSSHGERVVMRLLDKNATRLDLHSLGMTPVNHDNFRHLISRPHGIILVTGPTGSGKSTTLYAGLQELNSNERNILTVEDP
IEFDIDGIGQTQVNPKVDMTFARGLRAILRQDPDVVMVGEIRDLETAQIAVQASLTGHLVMSTLHTNTAVGAITRLRDMG
IEPFLISSSLLGVLAQRLVRTLCQDCKEPYEADKEQRKLFDALTLYRAKGCEKCNHKGYRGRTGIHELLMVDDKVQELIH
AEAGEQAMDKYIREHTPSIRSDGLDKVLQGVTSLEEVMRVTK

The query sequence (length=442) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 4pht:B 442 442 1.0000 1.0000 1.0000 0.0 1p9r:A, 1p9w:A, 4pht:A, 4pht:C
2 5tsh:E 387 385 0.4118 0.4703 0.4727 3.31e-125 5tsg:B, 5tsg:C, 5tsg:D, 5tsh:A, 5tsh:B, 5tsh:C, 5tsh:D, 5tsh:F, 5zfr:A, 5zfr:B, 5zfr:C
3 5oiu:C 386 383 0.4208 0.4819 0.4856 1.27e-121 5it5:F, 5it5:A, 5it5:B, 5it5:E, 5it5:C, 5it5:D, 5oiu:A, 5oiu:B, 5oiu:D, 5oiu:E, 5oiu:F
4 8dzg:A 420 392 0.2715 0.2857 0.3061 2.77e-37 8dze:A, 8dze:B, 8dze:C, 8dze:D, 8dze:E, 8dze:F, 8dzf:A, 8dzf:B, 8dzf:C, 8dzf:D, 8dzf:E, 8dzf:F, 8dzg:B, 8dzg:C, 8dzg:D, 8dzg:E, 8dzg:F
5 3jvv:C 337 286 0.2308 0.3027 0.3566 1.65e-35 3jvv:A, 3jvv:B
6 2ewv:A 343 277 0.2172 0.2799 0.3466 2.54e-32 2eww:A, 2gsz:F
7 5fl3:A 354 155 0.1697 0.2119 0.4839 3.30e-31
8 6ojz:D 361 256 0.2036 0.2493 0.3516 3.69e-31 6ojx:A, 6ojx:B, 6ojx:C, 6ojz:A, 6ojz:B, 6ojz:C, 6ojz:E, 6ojz:F, 6ok2:A, 6ok2:B, 6ok2:C, 6ok2:D, 6ok2:E, 6ok2:F, 6okv:A, 6okv:B, 6okv:C, 6okv:D, 6okv:E, 6okv:F, 6olm:A, 6olm:B, 6olm:C, 6olm:D, 6olm:E, 6olm:F
9 2oap:2 503 209 0.1403 0.1233 0.2967 1.57e-11 2oap:1, 2oaq:2
10 4ihq:A 512 152 0.1176 0.1016 0.3421 6.92e-10 4ihq:B, 4ihq:C
11 6bge:A 323 116 0.0837 0.1146 0.3190 1.20e-06 6bge:B, 1g6o:A, 1g6o:B, 1nly:A, 1nly:B
12 8rjf:A 424 122 0.0882 0.0920 0.3197 1.85e-05 8rjf:B, 8rjf:C, 8rjf:D, 8rjf:E, 8rjf:F, 8rkd:F, 8rkd:A, 8rkd:C, 8rkd:D
13 8xqw:A 988 60 0.0498 0.0223 0.3667 0.045
14 8ui7:A 643 28 0.0339 0.0233 0.5357 0.083 8ui8:A, 8ui9:A, 8uii:A
15 7oar:B 413 37 0.0339 0.0363 0.4054 0.092
16 7oar:A 442 37 0.0339 0.0339 0.4054 0.092 7bil:A, 7bil:B, 6s3h:A, 6s3h:B, 6s3i:A, 6s3m:A, 6s3m:B, 6s3n:A, 6s3n:B, 6s3o:A, 6s3p:A
17 8hpl:C 384 42 0.0498 0.0573 0.5238 0.14 7cag:C, 7cag:D, 8hpl:D, 8hpm:C, 8hpm:D, 8hpn:C, 8hpn:D, 8hpr:C, 8hpr:D, 8hps:C, 8hps:D
18 3pih:A 836 55 0.0498 0.0263 0.4000 0.41
19 6n9l:A 625 55 0.0498 0.0352 0.4000 0.51
20 7cte:D 406 109 0.0724 0.0788 0.2936 0.74 7ctf:D, 7ctg:D, 7jpo:D, 7jpp:D, 7jpq:D, 7jpr:D, 7jps:D, 5uj7:C, 5uj7:D, 5ujm:D
21 8swn:A 1135 34 0.0339 0.0132 0.4412 0.89
22 6nje:A 297 46 0.0317 0.0471 0.3043 1.0
23 7mqa:NS 914 39 0.0385 0.0186 0.4359 1.1 6o16:A, 6o16:B
24 6tej:B 585 58 0.0475 0.0359 0.3621 1.6
25 8ptk:f 4502 38 0.0294 0.0029 0.3421 2.0 8ptk:e
26 7z8f:e 4579 38 0.0294 0.0028 0.3421 2.1 5owo:A, 8pr2:f, 8ptk:m, 8ptk:n, 7z8f:f, 7z8f:m, 7z8f:n, 7z8h:A
27 5nug:A 2920 38 0.0294 0.0045 0.3421 2.3 5nug:B
28 8pqw:A 2892 38 0.0294 0.0045 0.3421 2.3 8pqy:A, 8pqz:A, 8pqz:J
29 7z8g:A 3047 38 0.0294 0.0043 0.3421 2.4 8fdu:A, 7z8l:f
30 8dyu:A 2562 38 0.0294 0.0051 0.3421 2.4 8dyv:A
31 8fcy:A 2864 38 0.0294 0.0045 0.3421 2.6 8fd6:A, 8fdt:A
32 4ymu:J 240 66 0.0520 0.0958 0.3485 2.7 4ymu:A, 4ymv:J, 4ymv:A
33 4v9h:AY 622 131 0.0747 0.0531 0.2519 3.1
34 4fxp:B 200 47 0.0362 0.0800 0.3404 3.3 4fxp:A, 4fxp:C, 3uie:A, 3uie:B, 3uie:C
35 3c41:J 242 66 0.0520 0.0950 0.3485 3.4 3c41:K, 3c4j:A, 3c4j:B, 2olj:A, 2olj:B, 2olk:A, 2olk:B, 2olk:C, 2olk:D, 2q0h:A, 2q0h:B
36 8bjf:A 1195 27 0.0317 0.0117 0.5185 3.6 8bwp:A, 8bwq:A, 8bwr:A, 8sx7:A, 8sx8:A, 8sxb:A
37 8c6j:V 934 81 0.0520 0.0246 0.2840 3.8 6hys:A, 6hys:B, 6hys:C, 6hys:D, 6hyt:A, 6hyt:B, 6hyt:C, 6hyt:D, 6hyu:A
38 8a8h:B 146 17 0.0249 0.0753 0.6471 3.9
39 8i4a:A 1218 27 0.0317 0.0115 0.5185 3.9 8bwo:A, 8i4c:A, 8j3w:A, 8j3z:A, 8xol:A, 8xom:A
40 7pnv:b 323 40 0.0407 0.0557 0.4500 4.0
41 5hau:1z 730 137 0.0814 0.0493 0.2628 4.1 2bm0:A, 2bm1:A, 1fnm:A, 6gzq:H1, 6gzx:H1, 6gzx:H2, 6gzz:H1, 6gzz:H2, 5hau:2z, 4m1k:A, 4myt:A, 4myu:A, 2om7:L, 5ot7:U, 6q95:G, 6ucq:1v, 6ucq:2v, 4v5f:AY, 4v5f:CY, 4v5m:AY, 4v5n:AY, 4v6t:AY, 4v8u:AY, 4v8u:CY, 4v90:AY, 4v9j:AY, 4v9j:CY, 4v9k:AY, 4v9k:CY, 4v9l:AY, 4v9l:CY, 4v9m:AY, 4v9m:CY, 4w29:AY, 4w29:CY, 4wpo:BZ, 4wpo:DZ, 4wqf:BZ, 4wqf:DZ, 4wqu:BZ, 4wqu:DZ, 4wqy:BZ, 4wqy:DZ
42 8iza:A 1246 27 0.0317 0.0112 0.5185 4.1 8iz7:A, 8iz9:A, 8xok:A
43 8bx8:A 4453 18 0.0294 0.0029 0.7222 4.3 7k58:A, 7k5b:A, 7kek:A
44 6zyw:C 4433 18 0.0294 0.0029 0.7222 4.3
45 8bwy:C 4264 18 0.0294 0.0030 0.7222 4.4
46 8r9r:A 255 28 0.0294 0.0510 0.4643 4.5
47 7moq:C 4159 18 0.0294 0.0031 0.7222 4.6 6zyy:C
48 8a22:Bw 349 54 0.0362 0.0458 0.2963 4.7 8apn:Bw, 8apo:Bw
49 7ln6:F 714 136 0.0792 0.0490 0.2574 5.1 3cf0:A, 3cf0:B, 3cf0:C, 3cf0:D, 3cf0:E, 3cf0:F, 3cf0:G, 3cf0:H, 3cf0:I, 3cf0:J, 3cf0:K, 3cf0:L, 3cf0:M, 3cf0:N, 6g2v:A, 6g2w:A, 6g2x:A, 6g2y:A, 6g2z:A, 6g30:A, 7lmz:F, 7ln0:F, 7ln1:F, 7ln2:F, 7ln3:F, 7ln4:F, 7ln5:F, 6mck:A, 6mck:B, 6mck:C, 6mck:D, 6mck:E, 6mck:F, 6mck:G, 6mck:H, 6mck:I, 6mck:J, 6mck:K, 6mck:L, 8vku:A, 8vku:B, 8vku:C, 8vku:D, 8vku:E, 8vku:F, 8vls:A, 8vls:B, 8vls:C, 8vls:D, 8vls:E, 8vls:F, 8vls:G, 8vls:H, 8vls:I, 8vls:J, 8vls:K, 8vls:L, 8vov:A, 8vov:B, 8vov:C, 8vov:D, 8vov:E, 8vov:F
50 5wch:A 350 74 0.0475 0.0600 0.2838 5.2 5wch:B, 5wch:C, 5wch:D
51 6ks6:d 524 51 0.0407 0.0344 0.3529 5.4 6ks6:D, 4v81:D, 4v81:L, 4v81:l, 4v8r:AD, 4v8r:Ad, 4v8r:BD, 4v8r:Bd, 4v94:D, 4v94:L, 4v94:d, 4v94:l, 7ylw:D, 7ylw:d, 7ylx:D, 7ylx:d, 7yly:D, 7yly:d
52 7yzp:C 448 21 0.0249 0.0246 0.5238 5.5 7yzp:D
53 6s85:D 375 21 0.0249 0.0293 0.5238 5.9 6s6v:C, 6s6v:D, 6s85:C, 7yzo:C, 7yzo:D, 7z03:D, 7z03:C
54 7z6h:K 439 17 0.0249 0.0251 0.6471 6.1
55 6d3r:A 1127 45 0.0430 0.0169 0.4222 6.7 6d3s:A
56 5jpq:q 169 43 0.0385 0.1006 0.3953 7.8 4v7r:AD, 4v7r:CD
57 6zww:C 749 40 0.0317 0.0187 0.3500 8.9 8po7:B, 8po8:A, 8po8:B, 6zww:A, 6zww:E, 6zww:G
58 8po7:A 594 20 0.0249 0.0185 0.5500 9.0
59 8ipr:A 504 42 0.0385 0.0337 0.4048 9.1 8ipr:D
60 7tfk:A 360 71 0.0430 0.0528 0.2676 9.6 7tfl:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218