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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
RRKRLADGLSVTQKVFVRSRNGGATKIVREHYLRSDIPCLSRSCTKCPQIVVPDAQNELPKFILSDSPLELSAPIGKHYV
VLDTNVVLQAIDLLENPNCFFDVIVPQIVLDEVRNKSYPVYTRLRTLCRDSDDHKRFIVFHNEFSEHTFVERLPNETIND
RNNRAIRKTCQWYSEHLKPYDINVVLVTNDRLNREAATKEVESNIITKSLVQYIELLPNADDIRDSIPQMTFSDFTFPEY
YSTARVMGGLKNGVLYQGNIQISEYNFLEGSVSLPRFSKPVLIVGQKNLNRAFNGDQVIVELLPQSEWKAPSSIVLDSEH
FDVNDNPDINTTVISDKQRRLLAKDAMIAQRSKKIQPTAKVVYIQRRSWRQYVGQLAPSSVDPQSSSTQNVFVILMDKCL
PKVRIRTRRAAELLDKRIVISIDSWPTTHKYPLGHFVRDLGTIESAQAETEALLLEHDVEYRPFSKKVLECLPAEGHDWK
APTKLDDPEAVSKDPLLTKRKDLRDKLICSIDPPGCVDINDALHAKKLPNGNWEVGVHIADVTHFVKPGTALDAEGAARG
TSVYLVDKRIDMLPMLLGTDLCSLKPYVDRFAFSVIWELDDSANIVNVNFMKSVIRSREAFSYEQAQLRIDDKTQNDELT
MGMRALLKLSVKLKQKRLEAGALNLASPEVKVHMDSETSDPNEVEIKKLLATNSLVEEFMLLANISVARKIYDAFPQTAM
LRRHAAPPSTNFEILNEMLNTRKNMSISLESSKALADSLDRCVDPEDPYFNTLVRIMSTRCMMAAQYFYSGAYSYPDFRH
YGLAVDIYTHFTSPIRRYCDVVAHRQLAGAIGYEPLSLTHRDKNKMDMICRNINRKHRNAQFAGRASIEYYVGQVMRNNE
STETGYVIKVFNNGIVVLVPKFGVEGLIRLDNLTEDPNSAAFDEVEYKLTFVPTNSDKPRDVYVFDKVEVQVRSVMDPIT
SKRKAELLLK

The query sequence (length=970) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 5c0w:J 970 970 1.0000 1.0000 1.0000 0.0 5k36:K, 5vzj:K
2 4ifd:J 948 970 0.9773 1.0000 0.9773 0.0 5c0x:J, 5jea:J, 2vnu:D
3 8qcf:K 915 970 0.9412 0.9978 0.9412 0.0
4 6h25:J 868 947 0.4206 0.4700 0.4308 0.0 6d6q:K, 6d6r:K
5 7tuv:A 672 679 0.2773 0.4003 0.3962 9.91e-161
6 8e29:A 692 751 0.2567 0.3598 0.3316 3.74e-98 8e28:A, 8e2a:A, 4pmw:A, 4pmw:B
7 8cdu:C 708 445 0.1392 0.1907 0.3034 4.85e-48 8cec:C, 8ced:C, 8cee:C
8 8cdv:C 457 338 0.1165 0.2473 0.3343 3.64e-47
9 5xgu:A 631 564 0.1577 0.2425 0.2713 8.03e-38 5xgu:B
10 7dic:A 646 429 0.1113 0.1672 0.2517 4.26e-30 7dcy:A, 7did:A, 7dol:A
11 2ix1:A 643 433 0.1010 0.1524 0.2263 3.60e-19 2id0:A, 2id0:B, 2id0:C, 2id0:D, 2ix0:A
12 2r7d:A 461 214 0.0649 0.1367 0.2944 3.05e-11 2r7d:B, 2r7d:C
13 2r7d:A 461 72 0.0258 0.0542 0.3472 2.86e-05 2r7d:B, 2r7d:C
14 6md3:C 180 171 0.0474 0.2556 0.2690 2.46e-08 6md3:A, 6md3:B, 6md3:D, 6md3:E, 6md3:F
15 8eih:D 256 46 0.0175 0.0664 0.3696 0.32
16 3o93:A 190 85 0.0227 0.1158 0.2588 0.88 3o90:A, 3o90:B, 3o90:C, 3o90:D, 3o91:A, 3o91:B, 3o91:C, 3o91:D, 3o92:A, 3o92:B, 3o92:C, 3o92:D, 3o93:B, 3o93:C, 3o93:D, 3o94:A, 3o94:B, 3o94:C, 3o94:D
17 8crx:P 128 31 0.0134 0.1016 0.4194 1.9 8cwo:P
18 5xon:A 1427 136 0.0351 0.0238 0.2500 3.3 6a5l:A, 6a5o:A, 6a5p:A, 6a5r:A, 6a5t:A, 6a5u:A, 8h0v:A, 8h0w:A, 8he5:A, 6inq:A, 6ir9:A, 6j4w:A, 6j4x:A, 6j4y:A, 6j4z:A, 6j50:A, 6j51:A, 8jh2:A, 8jh3:A, 8jh4:A, 7wbv:A, 7wbw:A, 7wbx:A, 5x4z:M, 5x50:A, 7xn7:A, 5xog:A, 7xse:A, 7xsx:A, 7xsz:A, 7xt7:A, 7xtd:A, 7xti:A, 8yfq:A
19 7r2g:B 351 103 0.0237 0.0655 0.2233 4.5 6cpm:C, 6cpm:D, 6crn:A, 6crn:B, 6crn:C, 6crn:D, 6gh9:A, 6gha:A, 6ml1:A, 6ml1:B, 7r2g:A
20 6f3h:B 790 88 0.0247 0.0304 0.2727 4.7 6f3h:A
21 7mxd:D 204 69 0.0186 0.0882 0.2609 4.8 8gje:L, 8gje:J, 8gje:K, 7ly9:C, 7ly9:I, 7mxd:U, 7n28:D, 7n28:K, 7n28:U, 7pc2:L, 7pc2:J, 5v8l:L, 5v8l:K, 5v8m:L, 5v8m:T, 5v8m:U
22 5cho:A 165 63 0.0216 0.1273 0.3333 5.8 5cho:C, 5cho:B, 5cho:D, 5cho:E, 5cho:F, 5cho:G, 5cho:H
23 5jh8:A 317 31 0.0134 0.0410 0.4194 7.3
24 8wrk:A 434 107 0.0258 0.0576 0.2336 7.4 8in7:A, 8ina:A, 8ind:A, 8inj:A, 8ino:A, 8inv:A, 8wrj:A
25 6g2a:A 361 63 0.0227 0.0609 0.3492 7.7 6g28:A, 3hfw:A, 6iux:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218