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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
RQYGGLKDQDRIFQNLYDNYGWDLASARKQGDWYKTKELILKGDTWIIDEIKKSGLRGRGGAGFPSGLKWSFMNPPGWEK
NEGPRYLVVNADEGEPGTCKDREIMRKDPHKLVEGCLLAGRAMNATAAYIYIRGEFYNEAAVLQTAINEAYAAGLIGKDA
CGSGYDFDVYIHRGMGAYVCGEETSLIESLEGKAGKPRLKPPFPAGVGLFGRPSTVTNVETVAVAPTILRRGGDWFASFG
RERNSGTKLFCISGNVNEPCTVEEEMSIPLRELLEKHCGGIKGGWDNLLGVIPGGCSVPILPKNICEDVLMDFDALKDVQ
SGLGTAAVIVINKQQDVIRAIQRFAAFYKHESCGQCTPCREGTTWLLKAMDRFRTGQAKEREIDMLYELTKDIEGHTICA
LGDAAAWPIQGLIRNFRPEMETRMKKFHDEVGAVSVGGWMKDARVEKGKVVGAPLPGVHH

The query sequence (length=460) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 7b0n:F 460 460 1.0000 1.0000 1.0000 0.0 6gcs:B, 7o6y:B, 7o71:B, 6rfq:B, 6rfr:B, 6rfs:B, 6y79:B, 6yj4:F
2 7zm7:B 456 452 0.7739 0.7807 0.7876 0.0 7zmb:B, 7zmg:B
3 8b9z:F 441 424 0.6870 0.7166 0.7453 0.0 8ba0:F, 8esw:V1, 8esz:V1
4 7v2c:A 433 426 0.6696 0.7113 0.7230 0.0 7ak5:F, 7ak6:F, 7b93:F, 8c2s:F, 8ca3:F, 8ca4:F, 8ca5:F, 7dgq:8, 7dgr:8, 7dgs:8, 7dgz:8, 7dh0:8, 7dkf:82, 6g2j:F, 6g72:F, 5gpn:c, 5gup:B, 8iao:F, 8iap:F, 8ib4:F, 8ib5:F, 8ib9:F, 8iba:F, 8ibd:F, 8ibe:F, 8ic2:F, 8ic3:F, 5lc5:F, 5ldw:F, 5ldx:F, 5lnk:1, 5o31:F, 8olt:F, 8om1:F, 7psa:F, 8pw5:1, 8pw6:1, 8pw7:1, 8q0a:F, 8q0f:F, 8q0j:F, 8q0m:F, 8q0o:F, 8q0q:F, 8q1p:F, 8q1u:F, 8q1y:F, 8q25:F, 8q45:F, 8q46:F, 8q47:F, 8q48:F, 8q49:F, 8q4a:F, 6q9d:V1, 6qa9:V1, 6qbx:V1, 6qc2:V1, 6qc3:V1, 6qc4:V1, 6qc5:V1, 6qc6:V1, 6qc7:V1, 6qc8:V1, 6qc9:V1, 6qca:V1, 6qcf:V1, 7qsd:F, 7qsk:F, 7qsl:F, 7qsm:F, 7qsn:F, 7qso:F, 7r41:F, 7r42:F, 7r43:F, 7r44:F, 7r45:F, 7r46:F, 7r47:F, 7r48:F, 7r4c:F, 7r4d:F, 7r4f:F, 7r4g:F, 8rgp:1, 8rgq:1, 8rgr:1, 8rgt:1, 8ud1:1F, 8ueo:1F, 8uep:1F, 8ueq:1F, 8uer:1F, 8ues:1F, 8uet:1F, 8ueu:1F, 8uev:1F, 8uew:1F, 8uex:1F, 8uey:1F, 8uez:1F, 8ugh:1F, 8ugi:1F, 8ugj:1F, 8ugn:1F, 8ugn:5F, 8ugr:1F, 8ugr:5F, 7v2d:A, 7v2e:A, 7v2f:A, 7v2h:A, 7v2k:A, 7v2r:A, 7v30:A, 7v31:A, 7v32:A, 7v33:A, 7v3m:A, 7vb7:A, 7vbn:A, 7vbz:A, 7vwj:A, 7vxp:A, 7vxu:A, 7vy8:A, 7vya:A, 7vyf:A, 7vyh:A, 7vyn:A, 7vz1:A, 7vzv:A, 7vzw:A, 7w00:A, 7w0h:A, 7w0r:A, 7w0y:A, 7w1o:A, 7w1p:A, 7w1t:A, 7w1u:A, 7w1v:A, 7w1z:A, 7w20:A, 7w2k:A, 7w2l:A, 7w2r:A, 7w2u:A, 7w2y:A, 7w31:A, 7w32:A, 7w35:A, 7w4c:A, 7w4d:A, 7w4e:A, 7w4f:A, 7w4g:A, 7w4j:A, 7w4k:A, 7w4l:A, 7w4m:A, 7w4n:A, 7w4q:A, 5xtb:A, 5xtd:A, 5xth:A, 5xti:A, 5xti:BA, 7zd6:1, 7zdh:1, 7zdj:1, 7zdm:1, 7zdp:1, 7zeb:1, 6zk9:1, 6zkc:1, 6zkd:1, 6zke:1, 6zkf:1, 6zkg:1, 6zkh:1, 6zki:1, 6zkj:1, 6zkk:1, 6zkl:1, 6zkm:1, 6zkn:1, 6zko:1, 6zkp:1, 6zkq:1, 6zkr:1, 6zks:1, 6zkt:1, 6zku:1, 6zkv:1, 6zr2:F, 6ztq:F
5 7aqr:F 434 416 0.6630 0.7028 0.7332 0.0 7a23:A, 7a24:A, 7ar7:F, 7ar8:F, 7arb:F, 8bed:F, 8bpx:F, 8bq5:F, 8bq6:F, 8e73:V1, 6x89:V1
6 8gym:v1 442 428 0.6609 0.6878 0.7103 0.0 8b6f:AD, 8bqs:AD, 8gym:V1, 8gzu:v1, 8gzu:V1, 7tgh:V1
7 7arc:F 430 424 0.6522 0.6977 0.7075 0.0 7ard:F
8 8iuf:V1 504 428 0.6283 0.5734 0.6752 0.0 8j9h:V1, 8j9i:V1, 8j9j:V1
9 8qby:F 421 420 0.5761 0.6295 0.6310 0.0
10 4hea:1 437 418 0.4174 0.4394 0.4593 1.55e-119 2fug:1, 2fug:A, 2fug:J, 2fug:S, 4hea:B, 6i0d:1, 6i0d:B, 6i1p:1, 6i1p:B, 3i9v:1, 3i9v:A, 3iam:1, 3iam:A, 3ias:1, 3ias:A, 3ias:J, 3ias:S, 3m9s:1, 3m9s:A, 6q8o:1, 6q8o:B, 6q8w:1, 6q8w:B, 6q8x:1, 6q8x:B, 6y11:1, 6y11:B, 2ybb:1, 6ziy:1, 6zjl:1, 6zjn:1, 6zjy:1
11 8e9h:F 436 403 0.4043 0.4266 0.4615 9.61e-114 8e9g:F, 8e9i:F
12 7p61:F 442 381 0.3370 0.3507 0.4068 1.31e-97 7awt:F, 7nyr:F, 7nyu:F, 7nyv:F, 7nz1:F, 7p62:F, 7p63:F, 7p64:F, 7p69:F, 7p7c:F, 7p7e:F, 7p7j:F, 7p7k:F, 7p7l:F, 7p7m:F, 7z7r:F, 7z7s:F, 7z7t:F, 7z7v:F, 7z80:F, 7z83:F, 7z84:F, 7zc5:F, 7zci:F
13 9fdv:B 419 381 0.3565 0.3914 0.4304 2.91e-93 9fdj:B, 9fdj:D, 9fdk:B, 9fdk:D, 9fdv:D, 9fe0:B, 9fe0:D, 9fe5:B, 9fe5:D, 9fe7:B, 9fe7:D, 9fe8:B, 9fe8:D, 9fea:B, 9fea:D, 9fif:B, 9fif:D, 9fih:B, 9fih:D, 9fii:B, 9fii:D, 9fij:B, 9fij:D, 9fil:B, 9fil:D, 6hl2:B, 6hl2:D, 6hl3:B, 6hl3:D, 6hl4:B, 6hl4:D, 6hla:B, 6hla:D, 6hli:B, 6hli:D, 6hlj:B, 6hlj:D, 6hlm:B, 6hlm:D, 7q5y:C, 7q5y:I, 7q5y:O, 7q5y:U, 6q9c:B, 6q9c:D, 6q9g:B, 6q9g:D, 6q9j:B, 6q9j:D, 6q9k:B, 6q9k:D, 8qg1:B, 8qg1:D, 8qgw:B, 8qgw:D, 8qh4:B, 8qh4:D, 8qh7:B, 8qh7:D, 8qhk:B, 8qhk:D, 6r7p:B, 6r7p:D, 6saq:B, 6saq:D
14 8a6t:B 630 408 0.3457 0.2524 0.3897 1.10e-91 8a6t:E, 8bew:B, 8bew:E
15 7q4v:B 599 389 0.3391 0.2604 0.4010 3.44e-86 8a5e:B, 7q4v:F, 7q4w:B, 7q4w:F
16 7t2r:B 425 379 0.3152 0.3412 0.3826 5.73e-83 7t2r:G, 7t30:B, 7t30:G
17 7p8n:B 613 374 0.3239 0.2431 0.3984 1.18e-81 7p5h:B, 7p5h:E, 7p5h:b, 7p5h:e, 7p8n:b, 7p91:b, 7p91:B, 7p92:B
18 6vw7:D 514 415 0.3304 0.2957 0.3663 2.40e-80 6vw7:B, 6vw8:B, 6vw8:D
19 8oh5:B 584 399 0.3478 0.2740 0.4010 3.46e-80 8oh5:E, 8oh5:H, 8oh5:K, 8oh9:B, 8oh9:E, 8oh9:H, 8oh9:K
20 7vw6:B 560 393 0.3304 0.2714 0.3868 1.68e-74 7e5z:B, 8j83:B, 7xqw:B
21 6tg9:B 493 387 0.3152 0.2941 0.3747 4.34e-69 6tg9:F, 6tga:B, 6tga:F
22 5xfa:A 581 393 0.2826 0.2238 0.3308 6.25e-65 5xf9:A, 5xf9:E, 5xfa:E
23 4wz7:B 370 51 0.0826 0.1027 0.7451 2.18e-14 6h8k:B
24 4wz7:B 370 62 0.0696 0.0865 0.5161 1.95e-07 6h8k:B
25 7zc6:C 435 145 0.0870 0.0920 0.2759 5.35e-06
26 8rbq:C 477 254 0.1457 0.1405 0.2638 4.24e-04 8ahx:C, 8rb8:C, 8rb9:C, 8rbm:C
27 7sol:A 1011 120 0.0587 0.0267 0.2250 0.73 7pvn:A
28 1kop:A 223 57 0.0348 0.0717 0.2807 0.99 8dpc:A, 8dpc:C, 8dpc:E, 8dpc:G, 8dpo:A, 8dpo:C, 8dpo:E, 8dpo:G, 8dqf:A, 8dqf:C, 8dqf:E, 8dqf:G, 8dr2:A, 8dr2:C, 8dr2:E, 8dr2:G, 8drb:A, 8drb:C, 8drb:E, 8drb:G, 8dyq:A, 8dyq:C, 8dyq:E, 8dyq:G, 1kop:B, 1koq:A, 1koq:B
29 4ay8:A 340 72 0.0391 0.0529 0.2500 1.1 4ay7:A, 4ay7:B, 4ay8:B
30 5k1s:A 358 29 0.0283 0.0363 0.4483 4.0 5k1s:C, 5k1s:B, 5k1s:D
31 3t2z:A 427 67 0.0370 0.0398 0.2537 6.9 3kpk:A, 3sx6:A, 3sxi:A, 3sy4:A, 3syi:A, 3sz0:A, 3szc:A, 3szf:A, 3szw:A, 3t0k:A, 3t14:A, 3t2k:A, 3t2y:A, 3t2z:B, 3t31:A
32 8brm:SB 216 66 0.0391 0.0833 0.2727 7.2 8br8:SB, 8bsi:SB, 8bsj:SB, 8btd:SB, 8btr:SB, 8fvy:C, 8g4s:C, 7pwf:C, 7pwo:C1

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218