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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
RQIKDLLRLVNTVVEVRDARAPFATSAYGVDFSRKETIILLNKVDIADEKTTKKWVEFFKKQGKRVITTHKGEPRKVLLK
KLSFDRLARVLIVGVPNTGKSTIINKLKGKRAGIQWFSLENGVKILDTPGILYKNIFSEDLAAKLLLVGSLPVERIEDQR
IFERAFEIFARSIGIESSFSEFFEDFARKRGLLKKGGVPDIERALMLFFTEVAQGKAGRVSFERPED

The query sequence (length=227) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 3cnl:A 233 228 1.0000 0.9742 0.9956 2.86e-161 3cnn:A, 3cno:A
2 1puj:A 261 255 0.3392 0.2950 0.3020 2.81e-29 6ppk:W
3 6g0z:A 290 262 0.3128 0.2448 0.2710 5.78e-26 6g0z:B, 6g12:A, 6g12:B, 6g14:B, 6g14:A, 6g15:A, 6g15:B
4 8pv1:Cd 462 246 0.3040 0.1494 0.2805 3.90e-16 8pv2:Cd, 8pv3:Cd, 8pv4:Cd, 8pv5:Cd, 8pv6:Cd, 8pv7:Cd, 8pv8:Cd, 8pvk:Cd, 8pvl:Cd
5 8fkt:NB 387 245 0.2863 0.1680 0.2653 4.87e-16 8fkp:NB, 8fku:NB, 8fkv:NB, 8fkw:NB, 8fkx:NB, 8fky:NB, 8fkz:NB, 8fl0:NB, 8ink:u, 8ipd:u, 8ipx:u, 8ipy:u
6 8fl2:NC 511 242 0.3216 0.1429 0.3017 3.55e-15 8fkz:NC, 8fl0:NC, 8fl3:NC, 8fl4:NC, 8idt:A, 8idy:A, 8ie3:A, 8ine:A, 8inf:A, 8ink:w, 8ipd:w, 8ipx:w, 8ipy:w, 8ir1:w, 8ir3:w
7 6n8j:m 378 227 0.2952 0.1772 0.2952 8.90e-14
8 7btb:m 469 230 0.2996 0.1450 0.2957 2.08e-13 7bt6:m, 6ft6:m, 3jct:m, 6m62:m, 7oh3:m, 7ohq:m, 7oht:m, 7ug6:m, 7uoo:m, 7uqb:m, 7uqz:m, 7uui:m, 7v08:m, 6ylg:m, 6ylh:m
9 7o9k:C 255 168 0.2203 0.1961 0.2976 7.60e-12 7o9m:C
10 6qtz:o 325 258 0.3040 0.2123 0.2674 3.10e-11 6qik:o, 6ri5:o, 6rzz:o, 6s05:o
11 7am2:BT 300 197 0.2115 0.1600 0.2437 9.29e-11
12 7pd3:z 311 187 0.2335 0.1704 0.2834 9.34e-11 8pk0:z, 8qsj:z
13 6yxx:EM 308 238 0.2467 0.1818 0.2353 1.08e-10
14 6lsr:1 247 169 0.2115 0.1943 0.2840 2.21e-09
15 6n8n:W 377 278 0.2996 0.1804 0.2446 2.78e-09 6n8o:W
16 5t62:W 306 255 0.2775 0.2059 0.2471 2.95e-09
17 6yxy:EM 330 272 0.2511 0.1727 0.2096 6.46e-09
18 7of1:m 229 170 0.2115 0.2096 0.2824 2.59e-07
19 8i9w:CL 397 296 0.3040 0.1738 0.2331 1.29e-06 8i9t:CL, 8i9v:CL, 8i9x:CL, 8i9y:CL, 8i9z:CL, 8ia0:CL, 8pv1:CL, 8pv2:CL, 8pv3:CL, 8pv4:CL, 8pv5:CL, 8pv6:CL, 8pv7:CL, 8pv8:CL, 8pvk:CL, 8pvl:CL
20 8csq:a 263 47 0.0925 0.0798 0.4468 1.88e-04
21 3w5j:A 194 65 0.1057 0.1237 0.3692 6.98e-04
22 5uz4:Z 323 110 0.1278 0.0898 0.2636 0.002 4a2i:V, 7boi:W, 7nar:W, 5no2:Z, 5no3:Z, 5no4:Z, 2rcn:A, 2ykr:W
23 7odt:t 316 76 0.0881 0.0633 0.2632 0.005
24 7nrc:So 347 102 0.1278 0.0836 0.2843 0.012
25 1mky:A 407 47 0.0881 0.0491 0.4255 0.012
26 1mky:A 407 51 0.0837 0.0467 0.3725 7.4
27 5ucv:A 187 52 0.0837 0.1016 0.3654 0.013
28 3ec1:A 311 115 0.1366 0.0997 0.2696 0.015 3ec1:B
29 2gj8:D 172 94 0.1101 0.1453 0.2660 0.029 2gj8:A, 2gj8:B, 2gj8:C, 2gj9:A, 2gj9:B, 2gj9:C, 2gj9:D, 2gja:A, 2gja:B
30 6h4d:A 274 105 0.1189 0.0985 0.2571 0.031
31 3i8x:B 261 77 0.0969 0.0843 0.2857 0.039 3hyt:A, 3hyt:B, 3hyt:C, 3i8x:A, 3i8x:C, 4r98:A, 4r98:B
32 7o9k:G 337 89 0.0881 0.0593 0.2247 0.042 7of5:x, 7of7:x
33 2qu8:A 194 51 0.0705 0.0825 0.3137 0.049
34 5m7h:A 420 52 0.0837 0.0452 0.3654 0.055 4dcs:A, 4dct:A, 4dcu:A, 2hjg:A, 5mbs:A, 5x4b:A, 5x4b:B
35 3iev:A 302 61 0.0925 0.0695 0.3443 0.059 7c1o:A, 3r9w:A, 3r9x:A
36 1xzq:A 449 99 0.1189 0.0601 0.2727 0.061 1xzq:B
37 8ir1:4 620 56 0.0749 0.0274 0.3036 0.081 8fkt:SR, 8fku:SR, 8fkv:SR, 8fkw:SR, 8fkx:SR, 8fky:SR, 8fkz:SR, 8fl0:SR, 8fl2:SR, 8fl3:SR, 8fl6:SR, 8fl7:SR, 8fl9:SR, 8fla:SR, 8flb:SR, 8flc:SR, 8fld:SR, 8fle:SR, 8flf:SR, 8idt:4, 8idy:4, 8ie3:4, 8ine:4, 8inf:4, 8ink:4, 8ipd:4, 8ipx:4, 8ipy:4, 8ir3:4, 6lss:4, 6lu8:4
38 8fl4:SR 593 56 0.0749 0.0287 0.3036 0.087 8fkr:SR, 8fks:SR
39 2h57:B 167 27 0.0661 0.0898 0.5556 0.094 2h57:A, 2h57:C, 6vbv:3
40 2e87:A 356 60 0.0925 0.0590 0.3500 0.11
41 2e87:A 356 26 0.0441 0.0281 0.3846 1.7
42 6vs4:A 223 168 0.1542 0.1570 0.2083 0.13 6vs4:B
43 3ieu:A 293 25 0.0617 0.0478 0.5600 0.13 3ieu:B
44 5dn8:A 405 50 0.0749 0.0420 0.3400 0.14
45 5dn8:A 405 66 0.0969 0.0543 0.3333 0.21
46 2dyk:A 150 29 0.0573 0.0867 0.4483 0.17 2dyk:B
47 6yxy:EQ 471 53 0.0837 0.0403 0.3585 0.20
48 8r1a:A 587 42 0.0925 0.0358 0.5000 0.22 2b8w:A, 2b8w:B, 2b92:A, 2b92:B, 2bc9:A, 8cqb:A, 8cqb:B, 2d4h:A, 1f5n:A, 6loj:B, 8r1a:B, 8r1a:C, 8r1a:D, 8r1a:E, 8r1a:F
49 8etc:b 415 55 0.0661 0.0361 0.2727 0.22 8esq:b, 8etj:b
50 8eti:b 391 55 0.0661 0.0384 0.2727 0.23 8esr:b, 8etg:b
51 2wib:A 261 77 0.0925 0.0805 0.2727 0.24 2wib:B, 2wic:A
52 6vkj:A 305 35 0.0837 0.0623 0.5429 0.24
53 7ohy:b 375 67 0.0925 0.0560 0.3134 0.27
54 6yxx:EA 532 25 0.0573 0.0244 0.5200 0.30 7aoi:XL, 6yxy:EA
55 3geh:A 442 69 0.0881 0.0452 0.2899 0.30
56 7r8e:A 548 53 0.0969 0.0401 0.4151 0.30 7fdv:A, 7fdv:D, 7oz1:A, 7oz1:B, 7r8d:A, 7r8d:B, 7r8e:B
57 8ui7:C 339 50 0.0705 0.0472 0.3200 0.31 8ui8:C, 8ui9:C, 8uii:C, 8umt:C, 8umu:C, 8umv:C, 8umw:C, 8umy:C, 8un0:C, 8unj:C, 6vvo:C, 7z6h:G
58 7am2:BU 463 61 0.0881 0.0432 0.3279 0.36
59 7rll:B 177 31 0.0661 0.0847 0.4839 0.44 7rll:A
60 7pug:A 829 61 0.0881 0.0241 0.3279 0.47 7pxq:A
61 6k1z:A 544 49 0.0881 0.0368 0.4082 0.52
62 2bbw:A 220 103 0.1013 0.1045 0.2233 0.52 2bbw:B
63 3j8g:X 418 49 0.0749 0.0407 0.3469 0.69
64 3j8g:X 418 22 0.0529 0.0287 0.5455 8.4
65 6jr7:A 812 87 0.1013 0.0283 0.2644 0.72 6jr7:B, 6jr7:C, 6jr7:D, 6jr8:A, 6jr8:B, 6jr8:C, 6jr8:D
66 2d4h:B 284 30 0.0749 0.0599 0.5667 0.72
67 8bob:C 412 49 0.0749 0.0413 0.3469 0.79 8bob:D
68 7e5a:B 471 35 0.0749 0.0361 0.4857 0.93 7e5a:A
69 1wf3:A 296 20 0.0573 0.0439 0.6500 0.96
70 7am2:BV 199 53 0.0749 0.0854 0.3208 0.96
71 2wjg:A 170 56 0.0837 0.1118 0.3393 1.0 2wjg:B, 2wjh:A, 2wjh:B, 2wji:A, 2wji:B, 2wjj:A, 2wjj:B
72 8hfr:v9 106 39 0.0749 0.1604 0.4359 1.0
73 8fac:A 1377 35 0.0617 0.0102 0.4000 1.2 8e04:A
74 7ckf:A 256 94 0.1278 0.1133 0.3085 1.3 7ckf:B
75 6ian:E 167 27 0.0529 0.0719 0.4444 1.3 6ia7:A, 6iae:A
76 7rr5:R 355 97 0.1145 0.0732 0.2680 1.4
77 8kie:y 363 24 0.0617 0.0386 0.5833 1.7
78 2yv5:A 293 114 0.1189 0.0922 0.2368 1.7
79 8e05:A 1749 53 0.0705 0.0091 0.3019 1.8 8e05:B, 8e06:A
80 7nvo:D 247 42 0.0705 0.0648 0.3810 1.8 7nvo:d
81 4v0l:A 168 21 0.0529 0.0714 0.5714 1.9 4v0k:A, 4v0k:B, 4v0l:B, 4v0m:A, 4v0m:C, 4v0m:E, 4v0m:G, 4v0n:A, 4v0n:C, 4v0n:E, 4v0n:G, 4v0o:A, 4v0o:C, 4v0o:E, 4v0o:G
82 7owj:F 197 26 0.0485 0.0558 0.4231 2.1 7owe:E, 7owe:F, 7owe:D, 7owe:A, 7owe:B, 7owe:C, 7owj:A, 7owj:B, 7owj:C, 7owj:D, 7owj:E, 7owk:B, 7owk:A, 7owk:C, 7owk:D, 7owk:E, 7owk:F, 7owl:A, 7owl:B, 7owl:C, 7owl:D, 7owl:E, 7owl:F
83 3geg:A 241 67 0.0793 0.0747 0.2687 2.6 3geg:B
84 3a1s:A 255 46 0.0573 0.0510 0.2826 2.6 3a1s:B, 3a1t:A, 3a1u:A, 3a1u:B
85 2cxx:A 184 52 0.0837 0.1033 0.3654 2.7 2cxx:B, 2cxx:C
86 3h2y:A 309 85 0.1013 0.0744 0.2706 2.7
87 7y9i:A 362 24 0.0529 0.0331 0.5000 2.7
88 1lnz:A 342 63 0.0881 0.0585 0.3175 2.8 1lnz:B
89 7nt5:B 395 82 0.0969 0.0557 0.2683 3.3 8c4h:C, 8c4h:D, 8c4h:E, 8c4h:F, 8c4h:G, 8c4h:H, 8c4h:I, 8c4h:J, 8c4h:K, 8c4h:L, 8c4h:M, 8c4h:N, 8c4h:A, 8c4h:B, 8c4h:a, 8c4h:b, 8c4h:c, 8c4h:d, 8c4h:e, 8c4h:f, 8c4h:g, 8c4h:h, 8c4h:i, 8c4h:j, 8c4h:k, 8c4h:l, 8c4h:m, 8c4h:n, 8cbw:A, 7nt5:A, 7nt5:C, 7nt5:D, 7nt5:E, 7nt5:F, 7nt5:G, 7nt5:H, 7nt5:I, 7nt5:J, 7nt5:K, 7nt5:L, 7nt5:M, 7nt6:H, 7nt6:J, 7nt6:K, 7nt6:L, 7nt6:M, 7nt6:N, 7nt6:O, 7nt6:C, 7nt6:D, 7nt6:E, 7nt6:F, 7nt6:G
90 2dby:A 355 18 0.0529 0.0338 0.6667 3.3
91 4bas:A 172 20 0.0441 0.0581 0.5000 3.6
92 2x77:A 181 33 0.0617 0.0773 0.4242 3.6 2x77:B
93 6uxv:I 109 31 0.0529 0.1101 0.3871 3.7 6uxw:I
94 3doe:A 189 35 0.0617 0.0741 0.4000 3.8 3dof:A, 4gok:B, 4gok:A, 1ksg:A, 1ksh:A, 1ksj:A
95 6bbp:A 520 45 0.0749 0.0327 0.3778 5.2 2a5d:A, 2a5f:A, 2a5g:A, 6bbq:A, 1e0s:A, 1fgy:A, 1fhw:A, 1fhw:B, 1fhx:A, 1fhx:B, 4fme:C, 4fme:F, 2j5x:A, 2j5x:B, 4kax:A, 4kax:B, 3n5c:A, 3n5c:B, 3pcr:B, 2r09:A, 2r09:B, 2r0d:A, 2r0d:B, 3vhx:A, 3vhx:C, 3vhx:E, 3vhx:G, 2w83:A, 2w83:B, 2w83:E, 7xrd:A, 7xrd:B, 7xrd:C, 7xrd:D
96 7x3u:D 439 37 0.0661 0.0342 0.4054 5.8
97 1u0l:A 278 142 0.1674 0.1367 0.2676 5.8 1u0l:B, 1u0l:C
98 5de3:A 166 20 0.0441 0.0602 0.5000 6.3 5di3:A
99 8fo9:F 2289 53 0.0705 0.0070 0.3019 6.5 9c61:A, 9c61:B, 8fo2:E, 8fo7:C, 8fo8:C, 8fo8:E, 8fo9:E, 7lht:A, 7lht:B, 7lhw:A, 7li3:A, 7li4:A, 6oje:A, 6oje:B, 6ojf:A, 6ojf:B, 7thy:A, 7thz:A, 6xaf:A, 6xaf:B, 2zej:B
100 8xql:A 240 51 0.0749 0.0708 0.3333 6.7
101 7aoz:I 464 56 0.0705 0.0345 0.2857 6.8 7ap8:I, 7ap9:I
102 8ips:B 588 103 0.1278 0.0493 0.2816 6.8 8ipt:A, 8ipt:E, 7zda:D, 7zdb:D, 7zdc:D, 7zde:D, 7zdf:D, 7zdg:D, 7zdk:D, 7zdl:D, 7zdr:D, 7zdt:D, 7zdu:D, 7zdv:D, 7zdw:D, 7ze5:D, 7zec:D
103 6xrs:B 392 20 0.0396 0.0230 0.4500 7.0 6xrs:A, 6xrs:D, 6xrs:C
104 4jyb:A 323 22 0.0573 0.0402 0.5909 7.0 8dpb:A, 8dpb:B, 4jyb:B, 4jyc:D, 4lc1:A, 4lc1:B, 2qm7:A, 2qm7:B
105 8sfe:d 489 37 0.0661 0.0307 0.4054 7.2 8sfe:D
106 7zbh:B 374 30 0.0529 0.0321 0.4000 7.4 7zbh:A, 7zbh:D, 7zbh:F, 7zbh:I, 7zbh:K
107 7x0s:I 521 37 0.0661 0.0288 0.4054 7.6 8i1u:D, 8i1u:L, 8i9u:D, 8i9u:L, 7nvl:D, 7nvl:d, 7nvm:D, 7nvm:d, 7nvn:D, 7nvn:d, 8sff:D, 8sff:d, 8sg8:D, 8sg8:d, 8sg9:D, 8sg9:d, 8sgc:D, 8sgc:d, 8sgl:D, 8sgl:d, 8sgq:D, 8sgq:d, 8sh9:D, 8sh9:d, 8sha:D, 8sha:d, 8shd:D, 8shd:d, 8she:D, 8she:d, 8shf:D, 8shf:d, 8shg:D, 8shg:d, 8shl:D, 8shl:d, 8shn:D, 8shn:d, 8sho:D, 8sho:d, 8shp:D, 8shp:d, 8shq:D, 8shq:d, 8sht:D, 8sht:d, 7trg:F, 7ttn:F, 7ttt:F, 7tub:F, 7x0s:M, 7x0v:I, 7x0v:M, 7x3j:d, 7x3u:d
108 7x3j:D 469 37 0.0661 0.0320 0.4054 7.7
109 8xuq:A 885 35 0.0573 0.0147 0.3714 8.1 8xuo:A, 8xuo:G, 8xuq:E, 8xuq:F, 8xuq:G, 8xuv:A, 8xuv:B, 8xuv:C, 8xuv:D, 8xuv:E, 8xuv:F, 8xuv:G, 8xuv:H, 8xuv:I, 8xuv:J, 8xuv:K, 8xuv:L
110 7dz7:V 238 47 0.0617 0.0588 0.2979 8.7 7dz8:V, 7e0i:V, 7e0k:V
111 8xqw:C 690 41 0.0617 0.0203 0.3415 9.7
112 8tzf:A 1589 52 0.0661 0.0094 0.2885 9.9

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218