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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
RPSVSVYSASSDSVVGTCPLPAVFTAPIRSDIVKFVHTNMAKNSRQAYAVNRLSGMNHSAHSWGTGRAVARIPRISGGGT
STSGAGAFGNMCRGGRMFAPTKIFRRWHRKINLHQKRFAVVSALAASSVPSLVMSRGHQIGNVPEVPLVVEDSIQGYEKT
KEAMAFLKAIAAIDDVNRVNDSREIRAGRGKMRNRRYVARRGPMLVMPNNKGTRAFRNIFGLDLANVSALNLLHLAPGGH
VGRFVIWTQSAFEQLDKIFGTFTEASAVKKGFTLPAPMLTNTDVTRIMQSEEVRRVLKPKKLQTPTNGMKNRRLRLRLNP
YVKRE

The query sequence (length=325) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 8a98:C 366 333 1.0000 0.8880 0.9760 0.0 8a3w:C, 6az3:C, 3jcs:C, 8ovj:C, 8rxh:LC, 8rxx:LC, 5t2a:p, 5t5h:r
2 8ova:Br 367 333 0.8708 0.7711 0.8498 0.0 8ove:Br, 4v8m:Br
3 7oya:C1 348 329 0.5662 0.5287 0.5593 1.61e-135 7oyb:C1
4 8ev3:C 362 331 0.5538 0.4972 0.5438 3.33e-130 8esq:C, 8esr:C, 8etc:C, 8etg:C, 8eug:C, 8eui:C
5 7oyc:C1 351 329 0.5846 0.5413 0.5775 3.67e-127
6 7f5s:LC 368 329 0.5846 0.5163 0.5775 4.20e-125 7a01:t2, 8a3d:F, 5aj0:AC, 8b5l:C, 8b6c:C, 9bdl:AL04, 9bdn:AL04, 9bdp:AL04, 7bhp:LC, 8bhf:l3, 8bpo:C2, 8btk:BC, 7cpu:LC, 7cpv:LC, 4d5y:C, 4d67:C, 6d90:C, 6d9j:C, 9f1b:BC, 9f1c:BC, 9f1d:BC, 8fkt:SA, 8fku:SA, 8fkv:SA, 8fkw:SA, 8fkx:SA, 8fky:SA, 8fkz:SA, 8fl2:SA, 8fl3:SA, 8fl4:SA, 8fl6:SA, 8fl7:SA, 8fl9:SA, 8fla:SA, 8flb:SA, 8flc:SA, 8fld:SA, 8fle:SA, 8flf:SA, 9fpz:LC, 9fq0:LC, 6frk:C, 6ftg:C, 6fti:C, 6ftj:C, 8g5y:LC, 8g5z:LC, 8g60:LC, 8g61:LC, 8g6j:LC, 8glp:LC, 6gz3:AC, 6gz4:AC, 6gz5:AC, 6hcf:C3, 6hcj:C3, 6hcm:C3, 6hcq:C3, 8idt:D, 8idy:D, 8ie3:D, 8ifd:1F, 8ife:1F, 8ine:D, 8inf:D, 8ink:D, 6ip5:1F, 6ip6:1F, 6ip8:1F, 8ipd:D, 8ipx:D, 8ipy:D, 8ir1:D, 8ir3:D, 3j7o:C, 3j7p:C, 3j7q:C, 3j7r:C, 3j92:C, 3jag:C, 3jah:C, 3jai:C, 3jaj:C, 3jan:C, 8jdj:I, 8jdk:I, 8jdl:I, 8jdm:I, 8k2c:LC, 5lks:LC, 6lqm:D, 6lsr:D, 6lss:D, 7ls1:F2, 7ls2:F2, 6lu8:D, 5lzs:C, 5lzt:C, 5lzu:C, 5lzv:C, 5lzw:C, 5lzx:C, 5lzy:C, 5lzz:C, 7mdz:C, 6mtb:C, 6mtc:C, 6mtd:C, 6mte:C, 7nfx:C, 7nwg:C3, 7nwh:C, 7nwi:C, 7o7y:BC, 7o7z:BC, 7o80:BC, 7o81:BC, 7obr:C, 8ohd:LC, 8oj0:LC, 8oj5:LC, 8oj8:LC, 6ole:C, 6olf:C, 6olg:AC, 6oli:C, 6olz:AC, 6om0:C, 6om7:C, 7ow7:F, 7oyd:C, 8p2k:BC, 6p5i:AC, 6p5j:AC, 6p5k:AC, 6p5n:AC, 8q7z:BC, 8q87:BC, 8qfd:C, 7qgg:C, 8qoi:LC, 7qvp:MC, 7qvp:LC, 7qwq:C, 7qwr:C, 7qws:C, 6qzp:LC, 6r5q:C, 6r6g:C, 6r6p:C, 6r7q:C, 8rjb:C, 8rjc:C, 8rjd:C, 8scb:C, 6sgc:C2, 6swa:C, 5t2c:F, 6t59:C3, 7tm3:C, 7toq:AL04, 7tor:AL04, 7tut:C, 7ucj:C, 7uck:C, 4ug0:LC, 4ujc:BC, 4ujd:AC, 4uje:CC, 4v5z:Bc, 4v6x:CC, 6w6l:C, 6xa1:LC, 7xnx:LC, 7xny:LC, 8xsx:LC, 8xsy:LC, 8xsz:LC, 6y0g:LC, 8y0w:LC, 8y0x:LC, 6y2l:LC, 6y57:LC, 6y6x:LC, 8yoo:LC, 8yop:LC, 6z6l:LC, 6z6m:LC, 6z6n:LC, 7zjw:LF, 7zjx:LF, 6zm7:LC, 6zme:LC, 6zmi:LC, 6zmo:LC, 6zvk:t2
7 8jiv:CC 376 331 0.5508 0.4761 0.5408 4.32e-125
8 8azw:s 398 322 0.5477 0.4472 0.5528 7.23e-123 8b2l:s3, 7qiw:F, 7qiz:F
9 4v6w:CC 392 331 0.5692 0.4719 0.5589 1.15e-122 6xu6:CC, 6xu7:CC, 6xu8:CC
10 6uz7:AC 360 330 0.5569 0.5028 0.5485 1.31e-121 5it7:CC
11 3j79:F 390 329 0.5323 0.4436 0.5258 1.34e-119 3jbn:AF, 3jbo:AF, 3jbp:AF, 8tpu:AF, 5umd:F
12 9bh5:CC 335 327 0.5200 0.5045 0.5168 7.18e-119 9cai:CC
13 8ip8:EB 399 330 0.5477 0.4461 0.5394 2.40e-115 8ipa:EB, 8ipb:EB
14 4v8p:BC 409 335 0.5415 0.4303 0.5254 9.43e-114 4v8p:CC, 4v8p:EC, 4v8p:GC
15 8c3a:l 361 331 0.5323 0.4792 0.5227 3.35e-113 8c3a:AY, 8cq7:l, 8cq7:AY, 8cqw:l, 8cqw:AY, 8cre:l, 8cre:AY, 8oeq:l, 8oeq:AY, 7pzy:l, 7q08:l, 7q0f:l, 7q0p:l, 7q0r:l, 8q5i:l
16 8aaf:l 361 331 0.5354 0.4820 0.5257 5.22e-110 8agt:l, 8agu:l, 8agv:l, 8agw:l, 8agx:l, 8agz:l, 5apn:C, 5apo:C, 7azy:p, 7b7d:LF, 8bip:LC, 8bjq:LC, 8bn3:L4, 8bqd:BE, 8bqx:BE, 8ccs:GG, 8cdl:GG, 8cdr:GG, 8ceh:GG, 8cf5:GG, 8cg8:GG, 8cgn:GG, 8civ:GG, 8cku:GG, 8cmj:GG, 5dat:L4, 5dat:l4, 5dc3:L4, 5dc3:l4, 5dge:L4, 5dge:l4, 5dgf:L4, 5dgf:l4, 5dgv:L4, 5dgv:l4, 6elz:C, 6em1:C, 6em3:C, 6em4:C, 6em5:C, 8eub:AC, 8evp:AC, 8evq:AC, 8evr:AC, 8evs:AC, 8evt:AC, 8ewb:AC, 8ewc:AC, 5fci:L4, 5fci:l4, 5fcj:L4, 5fcj:l4, 6ft6:C, 5gak:G, 6gq1:C, 6gqb:C, 6gqv:C, 5h4p:C, 6hd7:G, 8hfr:DO, 6hhq:l, 6hhq:CF, 5i4l:L4, 5i4l:l4, 6i7o:BE, 6i7o:YE, 3j6x:L4, 3j6y:L4, 3j77:L4, 3j78:L4, 3jct:C, 5jcs:C, 5juo:H, 5jup:H, 5jus:H, 5jut:H, 5juu:H, 8k2d:LC, 8k82:LC, 5lyb:L4, 5lyb:l4, 5m1j:C5, 6m62:C, 5mc6:BE, 5mei:l, 5mei:CF, 7mpi:AC, 7mpj:AC, 6n8j:C, 6n8k:C, 6n8l:C, 6n8m:F, 6n8n:F, 6n8o:F, 7n8b:AC, 7nac:C, 5ndg:L4, 5ndg:l4, 5ndv:L4, 5ndv:l4, 5ndw:L4, 5ndw:l4, 7nrc:LF, 7nrd:LF, 5obm:L4, 5obm:l4, 7of1:C, 7oh3:C, 7ohq:C, 7ohr:C, 7ohs:C, 7ohu:C, 7ohv:C, 7ohw:C, 7ohx:C, 7ohy:C, 6oig:C, 5on6:l, 5on6:CF, 7osa:uL4, 7osm:uL4, 8p8m:LH, 8p8n:LH, 8p8u:LH, 8pfr:LH, 6q8y:BE, 6qik:D, 6qt0:D, 6qtz:D, 7r7a:C, 6r84:G, 6r86:G, 6r87:G, 6ri5:D, 7rr5:LC, 6rzz:D, 6s05:D, 6s47:AF, 6snt:j, 6sv4:BE, 6sv4:YE, 6sv4:ZE, 6t4q:LC, 5t62:F, 5t6r:F, 6t7i:LC, 6t7t:LC, 6t83:Cy, 6t83:Fa, 5tbw:l, 5tbw:CF, 6tb3:BE, 5tga:L4, 5tga:l4, 5tgm:L4, 5tgm:l4, 6tnu:BE, 7too:AL04, 7top:AL04, 7u0h:C, 4u3m:L4, 4u3m:l4, 4u3n:L4, 4u3n:l4, 4u3u:L4, 4u3u:l4, 4u4n:L4, 4u4n:l4, 4u4o:L4, 4u4o:l4, 4u4q:L4, 4u4q:l4, 4u4r:L4, 4u4r:l4, 4u4u:L4, 4u4u:l4, 4u4y:L4, 4u4y:l4, 4u4z:L4, 4u4z:l4, 4u50:L4, 4u50:l4, 4u51:L4, 4u51:l4, 4u52:L4, 4u52:l4, 4u53:L4, 4u53:l4, 4u55:L4, 4u55:l4, 4u56:L4, 4u56:l4, 4u6f:L4, 4u6f:l4, 7ug6:C, 7uoo:C, 7uqb:C, 7uqz:C, 7v08:C, 4v4b:BD, 4v7f:D, 4v7h:BD, 4v7r:BD, 4v7r:DD, 4v88:BC, 4v88:DC, 4v8t:C, 4v8y:BC, 4v8z:BC, 8v83:C, 8v84:C, 8v87:C, 4v91:C, 6woo:C, 6xiq:C, 6xir:C, 8y0u:LC, 6ylg:C, 6ylh:C, 6ylx:C, 6yly:C, 5z3g:G, 7z34:C, 6z6j:LC, 6z6k:LC, 7zpq:BC, 7zrs:BC, 7zs5:BE, 7zuw:BC, 7zux:EC, 7zw0:LG
17 5xxb:C 394 325 0.5077 0.4188 0.5077 1.10e-106
18 8euy:C 329 331 0.4862 0.4802 0.4773 1.30e-106 8eth:C, 8eti:C, 8etj:C, 8eup:C
19 4v3p:LD 372 326 0.5108 0.4462 0.5092 3.62e-106 4v7e:CC
20 7olc:LC 363 336 0.5477 0.4904 0.5298 2.88e-105 8i9p:LC, 8i9r:LC, 8i9t:LC, 8i9v:LC, 8i9w:LC, 8i9x:LC, 8i9y:LC, 8i9z:LC, 8ia0:LC, 7old:LC, 8oo0:LC, 8pv1:LC, 8pv2:LC, 8pv3:LC, 8pv4:LC, 8pv5:LC, 8pv6:LC, 8pv7:LC, 8pv8:LC, 8pvk:LC, 8pvl:LC, 7z3n:LC, 7z3o:LC
21 7r81:F1 360 334 0.5231 0.4722 0.5090 4.65e-102
22 8fkp:SA 331 329 0.5169 0.5076 0.5106 4.65e-102 8fkq:SA, 8fkr:SA, 8fks:SA
23 6zj3:LR 365 326 0.5231 0.4658 0.5215 1.08e-101
24 7btb:C 336 331 0.4769 0.4613 0.4683 3.11e-96 7bt6:C, 6c0f:C, 6cb1:C, 7ohp:C
25 4v6i:BD 329 324 0.5046 0.4985 0.5062 1.45e-94
26 8p5d:LC0 327 282 0.4123 0.4098 0.4752 3.70e-93 8p60:LC0, 8p60:KC0, 7qca:LC0
27 6rm3:LC0 329 294 0.4369 0.4316 0.4830 4.75e-93
28 6zu5:LC0 325 322 0.4431 0.4431 0.4472 1.01e-92
29 8btd:LC 315 300 0.4462 0.4603 0.4833 8.17e-92 8br8:LC, 8brm:LC, 8bsi:LC, 8bsj:LC, 8btr:LC, 8fru:C, 7pwg:C, 7pwo:C2
30 7qep:L4 329 297 0.4123 0.4073 0.4512 2.59e-89
31 5xy3:C 362 297 0.3877 0.3481 0.4242 3.67e-72
32 8e5t:C 283 218 0.3169 0.3640 0.4725 2.32e-59
33 8e5t:C 283 39 0.0615 0.0707 0.5128 2.79e-05
34 8fl0:SA 274 221 0.3200 0.3796 0.4706 3.83e-59
35 8fl0:SA 274 53 0.0831 0.0985 0.5094 3.53e-08
36 8hku:AL4P 251 238 0.2677 0.3466 0.3655 2.05e-50 8hkv:AL4P, 8hky:AL4P, 8hkz:AL4P, 8hl1:AL4P, 8hl2:AL4P, 8hl3:AL4P, 8hl4:AL4P, 8hl5:AL4P
37 4v4n:AD 255 247 0.2769 0.3529 0.3644 1.49e-47 4v6u:BD
38 6skf:BE 255 259 0.2738 0.3490 0.3436 1.46e-44 6skg:BE, 6th6:BE
39 7oht:C 239 220 0.2677 0.3640 0.3955 1.21e-40
40 7oht:C 239 26 0.0462 0.0628 0.5769 0.19
41 3cc2:C 246 240 0.2431 0.3211 0.3292 2.27e-33 3cc4:C, 3cc7:C, 3cce:C, 3ccj:C, 3ccl:C, 3ccm:C, 3ccq:C, 3ccr:C, 3ccs:C, 3ccu:C, 3ccv:C, 3cd6:C, 3cma:C, 3cme:C, 3cpw:C, 3cxc:C, 1ffk:C, 3g4s:C, 3g6e:C, 3g71:C, 3i55:C, 3i56:C, 1jj2:C, 1k73:E, 1k8a:E, 1k9m:E, 1kc8:E, 1kd1:E, 1kqs:C, 1m1k:E, 1m90:E, 1n8r:E, 1nji:E, 2otj:C, 2otl:C, 3ow2:C, 1q7y:E, 1q81:E, 1q82:E, 1q86:E, 2qa4:C, 2qex:C, 1qvf:C, 1qvg:C, 1s72:C, 4v9f:C, 1vq4:C, 1vq5:C, 1vq6:C, 1vq7:C, 1vq8:C, 1vq9:C, 1vqk:C, 1vql:C, 1vqm:C, 1vqn:C, 1vqo:C, 1vqp:C, 1w2b:C, 1yhq:C, 1yi2:C, 1yij:C, 1yit:C, 1yj9:C, 1yjn:C, 1yjw:C
42 4v4p:AF 189 246 0.1969 0.3386 0.2602 6.28e-16 4v4r:BF, 4v4s:BF, 4v4t:BF
43 6eri:AE 212 68 0.0615 0.0943 0.2941 7.3 5h1s:G, 5mlc:F, 5mmi:E, 5mmm:E, 4v61:BG, 5x8p:E, 5x8t:E
44 5iko:A 807 24 0.0369 0.0149 0.5000 8.3 5ikp:A
45 1ogy:B 126 49 0.0462 0.1190 0.3061 8.4 1ogy:D, 1ogy:F, 1ogy:H, 1ogy:J, 1ogy:L, 1ogy:N, 1ogy:P
46 7c8z:A 383 67 0.0492 0.0418 0.2388 9.0 7c8z:C, 7c8z:E, 7c8z:G

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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