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TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
RPRILVPGKINPRVLERLPEMFETVRIERADAALVTADMRDVSGIAVSGKLPVPLMDAFPSLEIVANFGVGYDGVDVSRA
AARGIVVTNTPDVLTEEVADTAIGLLLNTLRLLPQAEQWLRQGRWVREGAFPLSPLSLRGRTVGLFGLGRIGLAIARRLE
AFGVSIAYHTRTPREGLGFTYHPTLVGMAEAVDTLIVIVPGTASTLKAVNADVLSALGPKGVLINVGRGSTVDEAALVTA
LQNGTIAGAGLDVFENEPNVPEALLSFPNVSLLPHVASASVVTRNAMSDLVVDNLKAWFSTGEALTPVAETPFRRRAI

The query sequence (length=318) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 5v6q:B 319 317 0.9969 0.9937 1.0000 0.0 5j23:A, 5j23:B, 5j23:C, 5j23:D, 5v6q:A, 5v6q:C, 5v6q:D, 5v7g:A, 5v7g:B, 5v7g:C, 5v7g:D, 5v7n:A, 5v7n:B, 5v7n:C, 5v7n:D
2 3baz:A 311 281 0.4340 0.4437 0.4911 6.11e-83
3 5aov:A 334 276 0.3742 0.3563 0.4312 1.75e-65
4 6bii:A 332 316 0.3899 0.3735 0.3924 5.83e-57 6bii:B
5 2dbq:A 333 265 0.3553 0.3393 0.4264 6.90e-48 2dbr:A, 2dbr:B, 2dbr:C, 2dbr:D, 2dbr:E, 2dbr:F, 2dbz:A, 2dbz:B
6 2gcg:A 324 244 0.3019 0.2963 0.3934 2.31e-42 2gcg:B, 2gcg:C, 2gcg:D
7 4e5p:A 332 316 0.3019 0.2892 0.3038 1.06e-35 4e5k:A, 4e5k:B, 4e5k:C, 4e5k:D, 4e5m:A, 4e5m:B, 4e5n:A, 4e5n:B, 4e5n:C, 4e5n:D, 4e5n:E, 4e5n:F, 4e5n:G, 4e5n:H, 4e5p:B, 4e5p:C, 4e5p:D, 4e5p:E, 4e5p:F, 4ebf:A, 4ebf:B, 4ebf:C, 4ebf:D, 4nu5:A, 4nu5:B, 4nu6:A, 4nu6:B
8 1wwk:A 304 287 0.2987 0.3125 0.3310 2.68e-35 1wwk:B
9 7dkm:A 306 293 0.2893 0.3007 0.3140 5.77e-35 7cvp:B, 6cwa:A, 6cwa:B, 7dkm:B, 7ewh:A, 7ewh:B, 2g76:A, 2g76:B, 5n53:B, 5n53:A, 5n6c:A, 5n6c:B, 5nzo:B, 5nzo:A, 5nzp:B, 5nzp:A, 5nzq:B, 5nzq:A, 5ofm:B, 5ofm:A, 5ofv:B, 5ofv:A, 5ofw:B, 5ofw:A, 6plf:A, 6plf:B, 6plg:A, 6plg:B, 6plg:C, 6plg:D, 6plg:E, 6plg:F, 6plg:G, 6plg:H, 6rih:A, 6rih:B, 6rj2:A, 6rj2:B, 6rj3:A, 6rj3:B, 6rj5:A, 6rj5:B, 6rj6:A, 6rj6:B, 7va1:B, 7va1:A, 7va1:C, 7va1:D
10 5z20:F 336 296 0.2925 0.2768 0.3142 1.41e-30 5z20:A, 5z20:B, 5z20:C, 5z20:D, 5z20:E
11 3dc2:A 526 292 0.2956 0.1787 0.3219 1.77e-30 3dc2:B, 3ddn:B
12 8ati:A 330 247 0.2610 0.2515 0.3360 3.07e-29 8ati:B, 8ati:C, 8ati:D, 4lcj:A, 4lcj:B, 4lcj:C, 4lcj:D, 4lcj:E, 4lcj:F, 4lcj:G, 4lcj:H, 2ome:A, 2ome:B, 2ome:C, 2ome:D, 2ome:E, 2ome:F, 2ome:G, 2ome:H, 6wkw:D, 6wkw:C, 6wkw:B, 6wkw:A
13 6cdf:A 333 234 0.2390 0.2282 0.3248 2.45e-28 8ari:A, 8ari:G, 8ari:D, 8ari:F, 8ari:E, 8ari:J, 8ari:H, 8ari:K, 8ari:I, 8ari:P, 8ari:L, 8ari:M, 8ari:N, 8ari:T, 8ari:O, 8ari:Q, 8ari:R, 8ari:U, 8ari:S, 8ari:X, 8ari:B, 8ari:C, 8ari:V, 8ari:W, 6cdr:A, 1hku:A, 1hl3:A, 2hu2:A, 7kwm:A, 4lce:A, 1mx3:A, 4u6q:A, 4u6s:A, 6v89:A, 6v8a:A
14 6ih6:A 330 300 0.2925 0.2818 0.3100 1.57e-27 6ih3:A, 6ih5:B, 6ih6:B
15 7cvp:A 254 210 0.2296 0.2874 0.3476 8.52e-26
16 3kb6:B 334 217 0.2075 0.1976 0.3041 5.05e-25 3kb6:A, 3kb6:C, 3kb6:D
17 6t9w:B 383 246 0.2107 0.1749 0.2724 5.09e-25 8bxx:AA, 8bxx:BB, 8bxx:CC, 8bxx:DD, 6t9w:A, 6t9w:C, 6t9x:B, 6t9x:A, 6t9x:C, 6t9x:D, 6tb6:B
18 5vg6:B 315 278 0.3050 0.3079 0.3489 9.35e-25 5vg6:A, 5vg6:C, 5vg6:D, 5vg6:E, 5vg6:F, 5vg6:G, 5vg6:H, 5vg6:I, 5vg6:J
19 2w2l:A 346 264 0.2296 0.2110 0.2765 1.42e-23 2w2l:B, 2w2l:C, 2w2l:D
20 2p9e:A 406 316 0.2862 0.2241 0.2880 1.90e-23 2p9c:A, 2p9c:B, 2p9e:B, 2p9e:C, 2p9e:D, 2p9g:A, 2p9g:B, 2pa3:A, 1psd:A, 1psd:B, 1sc6:A, 1sc6:B, 1yba:A, 1yba:B, 1yba:C, 1yba:D
21 4xyb:A 384 241 0.2327 0.1927 0.3071 2.20e-23 4xyb:B, 4xye:A, 4xye:B
22 4zgs:A 346 260 0.2358 0.2168 0.2885 1.39e-22 4zgs:B, 4zgs:C, 4zgs:D, 4zgs:E, 4zgs:F, 4zgs:G, 4zgs:H
23 7ya3:B 384 238 0.1887 0.1562 0.2521 1.06e-21 7ya3:A, 7ya4:A, 7ya4:B
24 3wr5:A 401 229 0.2075 0.1646 0.2882 2.45e-21 6juj:A, 6juj:B, 6juk:A, 6juk:B, 2nad:A, 2nad:B, 8oq2:A, 8oq2:B, 8oq2:C, 8oq2:D, 8oq2:E, 8oq2:F, 3wr5:B, 3wr5:C
25 4cuk:A 330 266 0.2421 0.2333 0.2895 3.67e-21 4cuk:D
26 1dxy:A 330 258 0.2075 0.2000 0.2558 9.30e-21
27 6ttb:A 331 265 0.2233 0.2145 0.2679 3.82e-20
28 5mh5:A 308 257 0.2484 0.2565 0.3074 4.05e-20 5mh5:B, 5mh6:A, 5mh6:B, 5mh6:C, 5mh6:D, 5mha:A, 5mha:B
29 4weq:A 316 262 0.2704 0.2722 0.3282 9.79e-20 4z0p:A
30 4xkj:A 332 253 0.2547 0.2440 0.3202 1.37e-19 4xkj:B
31 2gsd:A 399 247 0.2013 0.1604 0.2591 2.82e-19
32 7arz:A 361 248 0.1981 0.1745 0.2540 2.01e-18
33 4zqb:B 316 144 0.1792 0.1804 0.3958 5.84e-18 4zqb:A
34 1j49:A 332 265 0.2358 0.2259 0.2830 6.71e-18 1j49:B
35 3jtm:A 351 239 0.2044 0.1852 0.2720 1.65e-17 3n7u:A, 3n7u:B, 3n7u:C, 3n7u:D, 3n7u:E, 3n7u:F, 3n7u:G, 3n7u:H, 3n7u:I, 3n7u:J, 3n7u:K, 3n7u:L
36 1sc6:D 384 283 0.2579 0.2135 0.2898 2.86e-17 1sc6:C
37 3kbo:A 312 194 0.1792 0.1827 0.2938 3.92e-17 3kbo:B, 3kbo:C, 3kbo:D
38 2yq5:C 331 297 0.2421 0.2326 0.2593 8.44e-17 2yq5:A, 2yq5:B, 2yq5:D
39 7jqh:A 313 275 0.2390 0.2428 0.2764 1.19e-16 7jqi:A, 7jqj:A, 6ovl:A, 6oxn:A, 6p35:A
40 2dld:A 337 253 0.2233 0.2107 0.2806 1.20e-16 2dld:B
41 6p2i:A 307 246 0.2044 0.2117 0.2642 4.10e-16 6p2i:B
42 8grv:A 336 263 0.1981 0.1875 0.2395 1.19e-14
43 5bqf:A 317 321 0.2830 0.2839 0.2804 1.73e-14 5tsd:A, 5tsd:B, 4xcv:A
44 4prl:A 330 225 0.2013 0.1939 0.2844 2.34e-14 4prl:B
45 5dt9:A 379 286 0.2390 0.2005 0.2657 9.14e-14
46 2ekl:A 312 253 0.1824 0.1859 0.2292 2.19e-13
47 5z21:B 331 247 0.2075 0.1994 0.2672 6.27e-13 5z21:A, 5z21:C, 5z21:D
48 3oet:H 378 151 0.1572 0.1323 0.3311 2.40e-11 3oet:A, 3oet:B, 3oet:C, 3oet:D, 3oet:E, 3oet:F, 3oet:G
49 8j3p:A 374 217 0.1792 0.1524 0.2627 3.89e-10 8j3o:A, 8j3o:B, 8j3o:C, 8j3o:D, 8j3p:B, 8j3p:C
50 4njm:A 303 225 0.1698 0.1782 0.2400 4.17e-10 4njm:B, 4njo:A
51 6t8y:BBB 375 255 0.2075 0.1760 0.2588 7.22e-08 6t8y:AAA, 6t8y:CCC, 6t8y:DDD, 6t8z:AAA, 6t8z:BBB, 6t8z:CCC, 6t8z:DDD, 6t92:AAA, 6t92:BBB, 6t92:CCC, 6t92:DDD, 6t94:AAA, 6t94:BBB, 6t94:CCC, 6t94:DDD
52 6d4b:A 361 222 0.1730 0.1524 0.2477 2.75e-07 6d4b:B, 6d4c:A, 6d4c:B, 5dn9:A, 5dn9:B
53 1qp8:A 301 169 0.1352 0.1429 0.2544 3.71e-07 1qp8:B
54 2o4c:A 380 107 0.1006 0.0842 0.2991 3.32e-04 2o4c:B
55 5u5g:A 286 67 0.0723 0.0804 0.3433 0.002 5u5g:B, 5u5g:C, 5u5g:D
56 2rir:E 298 104 0.0849 0.0906 0.2596 0.011 2rir:A, 2rir:B, 2rir:C, 2rir:D, 2rir:F, 2rir:G, 2rir:H
57 4wji:A 293 107 0.1069 0.1160 0.3178 0.030
58 8p2j:C 293 73 0.0660 0.0717 0.2877 1.9 8ozv:A, 8ozw:A, 8ozw:B, 8p2j:A, 8p2j:B, 8p2j:D, 8p2j:E, 8p2j:F, 8p2j:G, 8p2j:H, 8p2j:I
59 8fl2:NY 526 77 0.0755 0.0456 0.3117 2.7 8fl3:NY, 8fl4:NY
60 5oey:C 326 102 0.0881 0.0859 0.2745 3.2 5oey:A, 5oey:B, 5ofu:A, 5ofu:B, 5ofu:C, 5ofu:D
61 2ywr:A 216 83 0.0786 0.1157 0.3012 3.3
62 8q03:A 318 65 0.0629 0.0629 0.3077 4.2 8q03:B, 8q03:C
63 3g1u:C 424 92 0.0660 0.0495 0.2283 5.1 3g1u:A, 3g1u:B, 3g1u:D
64 6smn:D 480 55 0.0472 0.0312 0.2727 5.3 6smn:A, 6smn:B, 6smn:C, 6smw:A, 6smw:B, 6smw:C, 6smw:D
65 7a3w:B 293 125 0.1069 0.1160 0.2720 5.8 7a3w:A
66 5oey:D 301 26 0.0314 0.0332 0.3846 6.8
67 7mfm:I 490 57 0.0597 0.0388 0.3333 7.5 7mfm:J, 7mft:I
68 1hyh:A 297 28 0.0409 0.0438 0.4643 8.0 1hyh:B, 1hyh:C, 1hyh:D
69 1w4x:A 533 52 0.0409 0.0244 0.2500 8.5 4c74:A, 4c77:A, 4d03:A, 4d04:A, 4ovi:A, 2ylr:A, 2yls:A, 2ylt:A, 2ylw:A, 2ylx:A, 2ylz:A, 2ym1:A, 2ym2:A
70 8er0:A 371 34 0.0377 0.0323 0.3529 9.8 8er0:B, 8er1:A, 6wg9:A, 6wg9:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218