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●I-TASSER ●I-TASSER-MTD ●C-I-TASSER ●CR-I-TASSER ●QUARK ●C-QUARK ●LOMETS ●MUSTER ●CEthreader ●SEGMER ●DeepFold ●DeepFoldRNA ●FoldDesign ●COFACTOR ●COACH ●MetaGO ●TripletGO ●IonCom ●FG-MD ●ModRefiner ●REMO ●DEMO ●DEMO-EM ●DMFold ●SPRING ●COTH ●Threpp ●PEPPI ●BSpred ●ANGLOR ●EDock ●BSP-SLIM ●SAXSTER ●FUpred ●ThreaDom ●ThreaDomEx ●EvoDesign ●BindProf ●BindProfX ●SSIPe ●GPCR-I-TASSER ●MAGELLAN ●ResQ ●STRUM ●DAMpred

●TM-score ●TM-align ●US-align ●MM-align ●RNA-align ●NW-align ●LS-align ●EDTSurf ●MVP ●MVP-Fit ●SPICKER ●HAAD ●PSSpred ●3DRobot ●MR-REX ●I-TASSER-MR ●SVMSEQ ●NeBcon ●ResPRE ●TripletRes ●DeepPotential ●WDL-RF ●ATPbind ●DockRMSD ●DeepMSA ●FASPR ●EM-Refiner ●GPU-I-TASSER

●BioLiP ●E. coli ●GLASS ●GPCR-HGmod ●GPCR-RD ●GPCR-EXP ●Tara-3D ●TM-fold ●DECOYS ●POTENTIAL ●RW/RWplus ●EvoEF ●HPSF ●THE-DB ●ADDRESS ●Alpaca-Antibody ●CASP7 ●CASP8 ●CASP9 ●CASP10 ●CASP11 ●CASP12 ●CASP13 ●CASP14

BioLiP
>protein
RPPLIERYRNLLPVSEKTPVISLLEGSTPLIPLKGPEEARKKGIRLYAKYEGLNPTGSFKDRGMTLAVSKAVEGGAQAVA
CASTGNTAASAAAYAARAGILAIVVLPAGYVALGKVAQSLVHGARIVQVEGNFDDALRLTQKLTEAFPVALVNSVNPHRL
EGQKTLAFEVVDELGDAPHYHALPVGNAGNITAHWMGYKAYHALGKAKRLPRMLGFQAAGAAPLVLGRPVERPETLATAI
RIGNPASWQGAVRAKEESGGVIEAVTDEEILFAYRYLAREEGIFCEPASAAAMAGVFKLLREGRLEPESTVVLTLTGHGL
KDPATAERVAELPPPVPARLEAVAAAAGLL

The query sequence (length=350) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length 		Aligned
length 		Identity
(normalized by query) 		Identity
(normalized by hit) 		Identity (normalized
by aligned length) 		E-value Homologs
to hit
1 3aex:A 351 350 1.0000 0.9972 1.0000 0.0 3aex:B, 3aey:A, 3aey:B, 1uim:A, 1uim:B, 1uin:A, 1uin:B, 1v7c:A, 1v7c:B, 1v7c:C, 1v7c:D
2 2zsj:A 350 348 0.5800 0.5800 0.5833 1.54e-141 2zsj:B, 2zsj:C, 2zsj:D
3 2d1f:A 349 326 0.5629 0.5645 0.6043 1.24e-129 2d1f:B
4 6nmx:A 350 331 0.5314 0.5314 0.5619 3.83e-128 6cgq:A, 6cgq:B, 6nmx:B, 6nmx:C, 6nmx:D
5 2c2g:A 448 320 0.3200 0.2500 0.3500 1.57e-54 2c2b:A, 2c2b:B, 2c2b:C, 2c2b:D, 2c2b:E, 2c2b:F, 2c2g:B
6 8y1j:A 502 294 0.2457 0.1713 0.2925 7.85e-10 8y1j:B
7 1pwh:A 327 289 0.2257 0.2416 0.2734 1.72e-09 1pwh:B, 1pwh:C, 1pwh:D
8 7mfj:BBB 319 329 0.2514 0.2759 0.2675 9.31e-09
9 1p5j:A 319 303 0.2143 0.2351 0.2475 1.46e-07
10 2gn2:A 326 143 0.1257 0.1350 0.3077 1.64e-07
11 3pc3:A 504 242 0.1857 0.1290 0.2686 7.14e-07 3pc2:A, 3pc4:A
12 6ahi:B 306 315 0.2200 0.2516 0.2444 9.94e-07
13 5ohx:A 488 136 0.1143 0.0820 0.2941 1.32e-06 5ohx:B
14 4f4f:A 464 159 0.1286 0.0970 0.2830 2.84e-06 4f4f:B
15 7nbc:AAA 323 281 0.2114 0.2291 0.2633 4.87e-06 3hmk:A, 3hmk:B, 3l6b:A, 3l6c:A, 3l6c:B, 3l6r:A, 7nbc:BBB, 7nbc:CCC, 7nbc:DDD, 7nbd:AAA, 7nbd:BBB, 7nbd:DDD, 7nbd:CCC, 7nbf:AAA, 7nbf:CCC, 7nbf:BBB, 7nbf:DDD, 7nbg:AAA, 7nbg:BBB, 7nbg:CCC, 7nbg:DDD, 7nbh:AAA, 7nbh:BBB, 7nbh:CCC, 7nbh:DDD, 6slh:AAA, 6slh:BBB, 6slh:CCC, 6slh:DDD, 5x2l:A, 5x2l:B, 6zsp:AAA, 6zsp:BBB, 6zuj:AAA, 6zuj:BBB, 6zuj:CCC, 6zuj:DDD
16 2zpu:A 319 132 0.1114 0.1223 0.2955 5.12e-06 1v71:A, 1wtc:A, 2zr8:A
17 5c3u:A 315 158 0.1171 0.1302 0.2595 1.41e-05
18 6xo2:A 294 60 0.0629 0.0748 0.3667 3.22e-05 7mfj:AAA, 6pmu:A, 6pmu:B
19 6xo2:A 294 100 0.1029 0.1224 0.3600 0.001 7mfj:AAA, 6pmu:A, 6pmu:B
20 2rhg:B 364 66 0.0714 0.0687 0.3788 4.28e-05
21 2rkb:A 318 288 0.2257 0.2484 0.2743 5.29e-05 2rkb:B, 2rkb:C, 2rkb:D, 2rkb:E
22 2bht:A 294 314 0.2200 0.2619 0.2452 5.67e-05 2bhs:A, 2bhs:B, 2bhs:C, 2bhs:D, 2bht:B, 2bht:C, 2bht:D, 2jc3:A, 2jc3:H, 2jc3:B, 2jc3:C, 2jc3:D, 2jc3:E, 2jc3:F, 2jc3:G, 2v03:A
23 5ey5:B 383 338 0.2343 0.2141 0.2426 6.90e-05 5ey5:D
24 7jmq:B 396 66 0.0714 0.0631 0.3788 7.49e-05 1a50:B, 1a5a:B, 1a5b:B, 1a5s:B, 8b03:B, 8b05:B, 8b06:B, 8b08:B, 1beu:B, 1bks:B, 5bw6:B, 1c29:B, 6c73:B, 1c8v:B, 1c9d:B, 3cep:B, 5cgq:B, 2cle:B, 2clf:B, 2clh:B, 2cli:B, 2clk:B, 2cll:B, 2clm:B, 2clo:B, 1cw2:B, 1cx9:B, 6d0v:B, 2dh5:A, 6duc:B, 6dz4:B, 6dzo:B, 1fuy:B, 4hn4:B, 4hpj:B, 4hpx:B, 4ht3:B, 2j9x:B, 2j9y:B, 2j9z:B, 7jhw:B, 7jll:B, 7jqw:B, 7jtt:B, 7k0b:B, 1k3u:B, 7k5a:B, 1k7e:B, 1k7f:B, 1k7x:B, 1k8x:B, 1k8y:B, 1k8z:B, 7ka1:B, 7kbn:B, 1kfb:B, 1kfc:B, 1kfe:B, 1kfj:B, 1kfk:B, 7kh6:B, 7ki7:B, 4kkx:B, 7kmc:B, 7kq9:B, 7kqf:B, 7ku9:B, 7kwv:B, 7kxc:B, 7kyt:B, 7l03:B, 7l1h:B, 7l47:B, 7l4d:B, 7l5h:B, 7lev:B, 7lgx:B, 7lkl:B, 7lpf:B, 7lt4:B, 7ltp:B, 7lut:B, 7lv5:B, 7lvx:B, 7lx1:B, 7ly8:B, 7m2l:B, 7m3s:B, 7me8:B, 7mt4:B, 7mt5:B, 7mt6:B, 6o1h:B, 3pr2:B, 1qop:B, 1qoq:B, 2rh9:B, 1tjp:B, 2trs:B, 2tsy:B, 1ttp:B, 1ttq:B, 2tys:B, 1ubs:B, 6vfd:B, 6vnt:B, 1wbj:B, 6wdu:B, 2wsy:B, 4wx2:B, 6wx3:B, 6x0c:B, 6xe3:B, 6xin:B, 6xnc:B, 6xoy:B, 6xrh:B, 6xsy:B, 6xt0:B, 4xug:B, 4y6g:B, 4zqc:B
25 2eco:A 302 123 0.1057 0.1225 0.3008 8.64e-05 2ecq:A, 2efy:A, 2efy:B, 1ve1:A
26 6hul:B 416 351 0.2714 0.2284 0.2707 9.37e-05
27 3dwg:A 325 151 0.1314 0.1415 0.3046 1.43e-04 3dwg:B, 3dwi:A, 3dwi:B, 5i6d:B, 5i6d:C, 5i6d:D, 5i7a:B, 5i7a:C, 5i7a:D, 5i7h:B, 5i7h:C, 5i7h:D, 5i7o:B, 5i7o:C, 5i7o:D, 5i7r:B, 5i7r:A, 5iw8:A, 5iw8:B
28 1vb3:A 428 302 0.2257 0.1846 0.2616 1.81e-04
29 5tci:H 406 337 0.2343 0.2020 0.2433 2.05e-04 6dwe:B, 6dwe:H, 6dwe:F, 6dwe:D, 6e9p:B, 6e9p:D, 6e9p:F, 6e9p:H, 5ocw:B, 5ocw:D, 5ocw:F, 5ocw:H, 5ocw:J, 5ocw:L, 5ocw:N, 5ocw:P, 5ocw:R, 5ocw:T, 5ocw:V, 5ocw:X, 5tcg:B, 5tcg:H, 5tcg:F, 5tcg:D, 5tci:B, 5tci:F, 5tci:D, 5tcj:B, 5tcj:H, 5tcj:F, 5tcj:D, 6u6c:B, 6u6c:D, 6u6c:F, 6u6c:H, 6uap:B, 6uap:D, 6uap:F, 6uap:H, 6ub9:B, 6ub9:D, 6ub9:F, 6ub9:H, 6usa:B, 6usa:D, 6usa:F, 6usa:H
30 1tdj:A 494 136 0.1171 0.0830 0.3015 2.13e-04
31 5iwc:A 297 97 0.0971 0.1145 0.3505 2.20e-04 5i6d:A, 5i7a:A, 5i7h:A, 5i7o:A, 5iwc:B
32 4lma:A 318 154 0.1257 0.1384 0.2857 2.53e-04 4lma:B
33 5z5c:B 336 146 0.1200 0.1250 0.2877 3.69e-04 5b53:A, 5b55:A, 5b55:B, 5z5c:A, 5z5c:C, 5z5c:D
34 5cvc:A 329 166 0.1200 0.1277 0.2530 3.84e-04 5cvc:B, 5cvc:C
35 1rqx:C 338 328 0.2286 0.2367 0.2439 7.42e-04 1rqx:A, 1rqx:B, 1rqx:D, 1tyz:A, 1tyz:B, 1tyz:C, 1tyz:D, 1tz2:A, 1tz2:B, 1tz2:C, 1tz2:D, 1tzj:A, 1tzj:B, 1tzj:C, 1tzj:D, 1tzk:A, 1tzk:B, 1tzk:C, 1tzk:D, 1tzm:A, 1tzm:B, 1tzm:C, 1tzm:D
36 8s5h:A 507 311 0.2200 0.1519 0.2476 0.001 4coo:A, 4coo:B, 1jbq:A, 1jbq:B, 1jbq:C, 1jbq:D, 1jbq:E, 1jbq:F, 4l0d:A, 4l0d:B, 4l27:B, 4l27:D, 4l27:A, 4l27:C, 4l28:A, 4l28:B, 4l28:C, 4l28:D, 4l3v:B, 4l3v:A, 4l3v:C, 1m54:A, 1m54:B, 1m54:C, 1m54:D, 1m54:E, 1m54:F, 5mms:A, 5mms:F, 5mms:B, 5mms:C, 5mms:D, 5mms:E, 4pcu:A, 4pcu:B, 7qgt:A, 7qgt:B, 8s5h:B, 8s5h:C, 8s5h:D, 8s5h:E, 8s5h:F, 8s5h:G, 8s5h:H, 8s5i:A, 8s5i:B, 8s5i:C, 8s5i:D, 8s5i:E, 8s5i:F, 8s5j:A, 8s5j:B, 8s5j:C, 8s5j:D, 8s5j:E, 8s5j:F, 8s5j:G, 8s5j:H, 8s5j:I, 8s5j:J, 8s5k:A, 8s5k:B, 8s5k:C, 8s5k:D, 8s5k:E, 8s5k:F, 8s5k:G, 8s5k:H, 8s5l:A, 8s5l:B, 8s5l:C, 8s5l:D, 8s5m:A, 8s5m:B, 8s5m:C, 8s5m:D, 8s5m:E, 8s5m:F, 8s5m:G, 8s5m:H, 8s5m:I, 8s5m:J, 8stw:A, 8stw:B, 8stw:C, 8stw:D, 8stw:E, 8stw:F, 4uuu:A, 4uuu:B
37 6c2h:A 345 93 0.0971 0.0986 0.3656 0.002 6c2q:A, 6c2z:A, 6c4p:A
38 5ixj:D 394 66 0.0714 0.0635 0.3788 0.002 6am8:A, 6am8:B, 6am8:C, 6am8:D, 6am9:A, 6am9:B, 6am9:C, 6am9:D, 6amh:A, 6amh:B, 6amh:C, 6amh:D, 6ami:A, 6ami:B, 6ami:C, 6ami:D, 6cut:A, 6cut:B, 6cut:C, 6cut:D, 6cuz:A, 6cuz:D, 5dw0:A, 5dw0:B, 5dw0:C, 5dw0:D, 5dw3:A, 5dw3:B, 5dw3:C, 5dw3:D, 5ixj:A, 5ixj:B, 5ixj:C, 7rnp:A, 7rnp:B, 7rof:A, 7rof:D, 5t6m:A, 5t6m:B, 5t6m:C, 5t6m:D, 1v8z:A, 1v8z:B, 1v8z:C, 1v8z:D, 5vm5:A, 5vm5:B, 5vm5:C, 5vm5:D, 1wdw:B, 1wdw:D, 1wdw:F, 1wdw:H, 1wdw:J, 1wdw:L
39 3bm5:A 338 89 0.0800 0.0828 0.3146 0.003 3bm5:B, 4il5:A, 4jbl:B, 4jbn:A, 2pqm:A, 2pqm:B
40 3ss7:X 437 237 0.1743 0.1396 0.2574 0.004 3ss9:X
41 6vju:B 317 172 0.1314 0.1451 0.2674 0.008
42 5ygr:B 365 206 0.1343 0.1288 0.2282 0.009
43 8vhh:A 389 81 0.0886 0.0797 0.3827 0.010 8egy:A, 8egy:B, 8egz:A, 8egz:B, 8eh0:A, 8eh0:B, 8eh1:A, 8eh1:B, 8vhh:B
44 6kr5:B 336 89 0.0743 0.0774 0.2921 0.012 6kr5:A
45 5xoq:A 310 38 0.0543 0.0613 0.5000 0.018 5xoq:B
46 5ygr:D 388 129 0.0971 0.0876 0.2636 0.019 5ygr:A, 5ygr:C
47 5kzm:B 395 66 0.0657 0.0582 0.3485 0.022
48 3vbe:C 329 146 0.1143 0.1216 0.2740 0.024 3vbe:A, 3vbe:B, 3vbe:D, 3vc3:A, 3vc3:B, 3vc3:C, 3vc3:D, 3vc3:E, 3vc3:F
49 4lmb:A 310 153 0.1200 0.1355 0.2745 0.027
50 1ve5:A 308 127 0.1114 0.1266 0.3071 0.036 1ve5:B
51 7xnz:B 458 114 0.1086 0.0830 0.3333 0.038 7xnz:A, 7xnz:C, 7xnz:D, 7xoh:B, 7xoh:A, 7xoh:C, 7xoh:D, 7xoy:B, 7xoy:A, 7xoy:C, 7xoy:D
52 1ve5:D 280 88 0.0857 0.1071 0.3409 0.043 1ve5:C
53 5xem:A 302 118 0.0857 0.0993 0.2542 0.053 5xem:B, 5xen:A, 5xen:B, 5xeo:A, 5xeo:B
54 8b9w:A 329 94 0.0771 0.0821 0.2872 0.098 8b9w:B
55 4air:A 304 92 0.0857 0.0987 0.3261 0.20 4air:B
56 2isq:A 320 93 0.0829 0.0906 0.3118 0.21 1z7w:A, 1z7y:A
57 4d9k:A 366 124 0.0943 0.0902 0.2661 0.24 4d9k:B, 4d9k:C
58 5b1i:A 303 146 0.1000 0.1155 0.2397 0.25 5b1i:B, 5b1i:C, 5b1i:D, 5b1i:E, 5b1i:F, 5b1i:G, 5b1i:H
59 5b36:B 383 93 0.0886 0.0809 0.3333 0.31 5b36:A, 5b3a:A, 5b3a:B, 6l0p:A, 6l0p:B, 6l0p:C, 6l0p:D, 6l0q:A, 6l0q:B, 6l0q:C, 6l0q:D, 6l0r:A, 6l0r:B, 6l0r:C, 6l0r:D, 6l0s:A, 6l0s:B, 6l0s:C, 6l0s:D, 3vsa:A, 3vsa:B, 3vsc:A, 3vsc:B, 3vsd:A, 3vsd:B, 1wkv:A, 1wkv:B
60 3t4p:A 319 92 0.0857 0.0940 0.3261 0.31 3tbh:A
61 4d9n:A 391 124 0.0943 0.0844 0.2661 0.33 4d9m:A, 4d9m:B, 4d9n:B
62 5d84:A 318 317 0.2143 0.2358 0.2366 0.34 5d85:A, 5d86:A, 5d87:A
63 6v82:B 391 57 0.0629 0.0563 0.3860 0.39
64 6xwl:C 477 87 0.0800 0.0587 0.3218 0.68 6xwl:F, 6xwl:A, 6xwl:B, 6xwl:D, 6xwl:E, 6xyl:A, 6xyl:B, 6xyl:C, 6xyl:D, 6xyl:E, 6xyl:F, 6y21:D, 6y21:A, 6y21:B, 6z3s:D, 6z3s:A, 6z3s:B, 6zs7:D, 6zs7:A, 6zs7:B, 6zs7:C, 6zs7:E, 6zs7:F
65 3r0x:A 438 237 0.1714 0.1370 0.2532 0.68
66 1d6s:A 322 49 0.0486 0.0528 0.3469 0.87 1d6s:B, 1fcj:A, 1fcj:B, 1fcj:C, 1fcj:D, 1oas:A, 1oas:B, 6z4n:AAA, 6z4n:BBB
67 3x44:A 321 92 0.0800 0.0872 0.3043 0.98 3x43:A, 3x43:B, 3x43:C, 3x43:D, 3x43:E, 3x43:F, 3x43:G, 3x43:H, 3x44:B
68 4aec:A 323 93 0.0800 0.0867 0.3011 1.4 4aec:B
69 8b9y:C 330 100 0.0857 0.0909 0.3000 1.5 8b9y:A, 8b9y:B, 8b9y:D
70 7n2t:A 309 93 0.0800 0.0906 0.3011 1.6
71 8g1y:A 496 170 0.1286 0.0907 0.2647 1.9 8g1y:B
72 4ewv:B 492 52 0.0600 0.0427 0.4038 2.0 4ewv:A
73 8bh3:C 668 82 0.0686 0.0359 0.2927 2.0 8bh3:L, 8bhy:C, 8bhy:L, 8bot:H, 8bot:U, 7k0y:C, 7nfc:H, 7sgl:C, 7z87:C, 7z88:C
74 4epm:A 554 52 0.0600 0.0379 0.4038 2.2 4eq4:A, 4eq4:B, 4eql:A, 4eql:B, 4l39:A, 4l39:B, 6oms:A, 6oms:B
75 6zhe:C 705 82 0.0686 0.0340 0.2927 2.3 8asc:B, 8asc:F, 8asc:L, 8asc:P, 6erf:B, 6erf:D, 6erf:F, 6erf:H, 6erg:E, 6erg:B, 6erh:B, 6erh:D, 8eza:K, 8eza:B, 8ezb:B, 8ezb:K, 1jey:B, 7k1k:C, 7lsy:B, 7lsy:K, 7lt3:B, 7lt3:K, 7nfe:C, 7su3:C, 5y3r:B, 7z6o:B, 6zha:C, 6zhe:H, 7zt6:B, 7zvt:B, 7zwa:B
76 8h4q:N 488 121 0.0943 0.0676 0.2727 2.6 8h4h:N, 8h4h:A, 8h4q:A
77 7moq:C 4159 40 0.0457 0.0038 0.4000 3.3 6zyy:C
78 8bwy:C 4264 40 0.0457 0.0038 0.4000 3.3
79 6zyw:C 4433 40 0.0457 0.0036 0.4000 3.3
80 7mex:A 1737 43 0.0457 0.0092 0.3721 3.4 6kgi:B, 7mey:A, 3nih:A, 3nii:A, 3nij:A, 3nik:B, 3nik:D, 3nik:A, 3nik:F, 3nil:D, 3nil:A, 3nil:B, 3nil:F, 3nim:B, 3nim:F, 3nim:A, 3nim:D, 3nin:A, 3nin:B, 3nis:A, 3nis:B, 3nis:D, 3nis:F, 3nit:A
81 5lwv:A 711 32 0.0400 0.0197 0.4375 9.5 5bnw:A, 6e37:A, 8fe6:A, 8fe6:C, 8fe6:E, 8fe6:G, 4gyw:A, 4gyy:A, 4gyy:C, 4gz3:A, 5hgv:A, 5nps:A, 6tka:AAA, 5vie:A, 5vie:C, 5vif:A
82 7yeh:A 1020 32 0.0400 0.0137 0.4375 9.6 4ay5:A, 4ay5:B, 4ay5:C, 4ay5:D, 4ay6:A, 4ay6:B, 4ay6:C, 4ay6:D, 5c1d:A, 4cdr:A, 4cdr:B, 4cdr:C, 4cdr:D, 8cm9:A, 8cm9:B, 8cm9:D, 8cm9:C, 8fe7:A, 8fe7:C, 8fe7:E, 8fe7:G, 8fuf:A, 8fuf:C, 8fuf:E, 8fuf:G, 4gyw:C, 4gz3:C, 4gz5:A, 4gz5:B, 4gz5:C, 4gz5:D, 4gz6:A, 4gz6:B, 4gz6:C, 4gz6:D, 5hgv:C, 6ibo:A, 5lvv:A, 6ma1:A, 6ma2:A, 6ma3:A, 6ma4:A, 6ma5:A, 4n39:A, 4n3a:A, 4n3b:A, 4n3c:A, 5npr:A, 3pe3:A, 3pe3:B, 3pe3:C, 3pe3:D, 3pe4:A, 3pe4:C, 6q4m:A, 3tax:A, 3tax:C, 1w3b:A, 4xi9:A, 4xi9:B, 4xi9:C, 4xi9:D, 4xif:A, 4xif:B, 4xif:C, 4xif:D

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).

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