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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
RPEIIVIDLKDHVLGRAAAVVAKQLLLGKKITVVRCEQLNIAGTEIRNKIKYLQYLRKRKLTNPTKGPFHHRAPSDVFVR
TVRSMLPRYTKRGMKALNSLVAYEGIPPNVVRTGGRVVIPRAQRHVCYRSERPYTVLGNMCKHVGWKYSDVVANLEKARV
EKASRHHEKQAKLREAWKAARKEALAKMPKHNVEVLKKFGYA

The query sequence (length=202) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 8a98:H 221 202 0.9901 0.9050 0.9901 9.46e-149 8a3w:H, 6az3:H, 3jcs:H, 8ovj:H, 8rxh:LH, 8rxx:LH, 5t2a:M
2 5t5h:O 202 201 0.8416 0.8416 0.8458 1.10e-127
3 8ova:BO 221 202 0.8119 0.7421 0.8119 1.11e-121 8ove:BO, 4v8m:BO
4 8glp:LO 202 198 0.4802 0.4802 0.4899 5.20e-58 7a01:w2, 8a3d:I, 5aj0:AO, 8b5l:O, 8b6c:O, 9bdl:AL16, 9bdn:AL16, 9bdp:AL16, 7bhp:LO, 8bhf:B1, 8bpo:N2, 8btk:BO, 7cpu:LO, 7cpv:LO, 4d5y:O, 4d67:O, 6d90:O, 6d9j:O, 9f1b:BO, 9f1c:BO, 9f1d:BO, 7f5s:LO, 8fkp:L7, 8fkq:L7, 8fkr:L7, 8fks:L7, 8fkt:L7, 8fku:L7, 8fkv:L7, 8fkw:L7, 8fkx:L7, 8fky:L7, 8fkz:L7, 8fl0:L7, 8fl2:L7, 8fl3:L7, 8fl4:L7, 8fl6:L7, 8fl7:L7, 8fl9:L7, 8fla:L7, 8flb:L7, 8flc:L7, 8fld:L7, 8fle:L7, 8flf:L7, 6frk:O, 6ftg:O, 6fti:O, 6ftj:O, 8g5y:LO, 8g5z:LO, 8g60:LO, 8g61:LO, 8g6j:LO, 6gz3:AO, 6gz4:AO, 6gz5:AO, 6hcf:O3, 6hcj:O3, 6hcm:O3, 6hcq:O3, 8idt:V, 8idy:V, 8ie3:V, 8ifd:2I, 8ife:2I, 8ine:V, 8inf:V, 8ink:V, 6ip5:2I, 6ip6:2I, 6ip8:2I, 8ipd:V, 8ipx:V, 8ipy:V, 8ir1:V, 8ir3:V, 3j7o:O, 3j7p:O, 3j7q:O, 3j7r:O, 3j92:O, 3jag:O, 3jah:O, 3jai:O, 3jaj:O, 3jan:O, 8jdj:T, 8jdk:T, 8jdl:T, 8jdm:T, 8k2c:LO, 5lks:LO, 6lqm:V, 6lsr:V, 6lss:V, 7ls1:I2, 7ls2:I2, 6lu8:V, 5lzs:O, 5lzt:O, 5lzu:O, 5lzv:O, 5lzw:O, 5lzx:O, 5lzy:O, 5lzz:O, 7mdz:O, 6mtb:O, 6mtc:O, 6mtd:O, 6mte:O, 7nfx:O, 7nwg:O3, 7nwh:O, 7nwi:O, 7o7y:BO, 7o7z:BO, 7o80:BO, 7o81:BO, 7obr:O, 8ohd:LO, 8oj0:LO, 8oj5:LO, 8oj8:LO, 6ole:P, 6olf:P, 6olg:AO, 6oli:P, 6olz:AO, 6om0:P, 6om7:P, 7ow7:I, 7oyc:O1, 7oyd:O, 8p2k:BO, 6p5i:AO, 6p5j:AO, 6p5k:AO, 6p5n:AO, 8q7z:BO, 8q87:BO, 8qfd:O, 7qgg:P, 8qoi:LO, 7qvp:LO, 7qvp:MO, 7qwq:O, 7qwr:O, 7qws:O, 6qzp:LO, 6r5q:O, 6r6g:O, 6r6p:O, 6r7q:O, 8rjb:O, 8rjc:O, 8rjd:O, 8scb:O, 6sgc:O2, 6swa:N, 5t2c:I, 6t59:O3, 7tm3:O, 7toq:AL16, 7tor:AL16, 7tut:O, 7ucj:O, 7uck:O, 4ug0:LO, 4ujc:BO, 4ujd:AO, 4uje:CO, 4v5z:Bj, 4v6x:CO, 6w6l:P, 6xa1:LO, 7xnx:LO, 7xny:LO, 8xsx:LO, 8xsy:LO, 8xsz:LO, 6y0g:LO, 8y0w:LO, 8y0x:LO, 6y2l:LO, 6y57:LO, 6y6x:LO, 8yoo:LO, 8yop:LO, 6z6l:LO, 6z6m:LO, 6z6n:LO, 7zjw:LR, 7zjx:LR, 6zm7:LO, 6zme:LO, 6zmi:LO, 6zmo:LO, 6zvk:w2
5 7oya:O1 204 198 0.4604 0.4559 0.4697 1.19e-55 7oyb:O1
6 8esq:O 196 199 0.4802 0.4949 0.4874 4.80e-53 8esr:O, 8etc:O, 8etg:O, 8eth:O, 8eti:O, 8etj:O, 8eug:O, 8eui:O, 8eup:O, 8euy:O, 8ev3:O
7 4v6w:CO 205 198 0.4554 0.4488 0.4646 3.93e-50 6xu6:CO, 6xu7:CO, 6xu8:CO
8 5it7:OO 198 198 0.4455 0.4545 0.4545 6.97e-50 6uz7:AO
9 4v6i:BK 199 167 0.4059 0.4121 0.4910 4.60e-49 8aaf:B, 8agt:B, 8agu:B, 8agv:B, 8agw:B, 8agx:B, 8agz:B, 5apn:O, 5apo:O, 7azy:V, 7b7d:LQ, 8bip:LO, 8bjq:LO, 8bn3:M6, 8bqd:AU, 8bqx:AU, 7bt6:O, 7btb:O, 6c0f:O, 6cb1:O, 8ccs:A, 8cdl:A, 8cdr:A, 8ceh:A, 8cf5:A, 8cg8:A, 8cgn:A, 8civ:A, 8cku:A, 8cmj:A, 5dat:M6, 5dat:m6, 5dc3:M6, 5dc3:m6, 5dge:M6, 5dge:m6, 5dgf:M6, 5dgf:m6, 5dgv:M6, 5dgv:m6, 8e5t:O, 6elz:O, 6em1:O, 6em3:O, 6em4:O, 6em5:O, 8eub:AO, 8evp:AO, 8evq:AO, 8evr:AO, 8evs:AO, 8evt:AO, 8ewb:AO, 8ewc:AO, 5fci:M6, 5fci:m6, 5fcj:M6, 5fcj:m6, 6ft6:O, 5gak:Q, 6gq1:O, 6gqb:O, 6gqv:O, 5h4p:O, 6hd7:Q, 8hfr:O6, 6hhq:w, 6hhq:CQ, 5i4l:M6, 5i4l:m6, 6i7o:AU, 6i7o:XU, 3j6x:56, 3j6y:56, 3j77:66, 3j78:66, 3jct:O, 5jcs:O, 5juo:T, 5jup:T, 5jus:T, 5jut:T, 5juu:T, 8k2d:LO, 8k82:LO, 5lyb:M6, 5lyb:m6, 5m1j:K5, 6m62:O, 5mc6:AU, 5mei:w, 5mei:CQ, 7mpi:AO, 7mpj:AO, 6n8j:O, 6n8k:O, 6n8l:O, 6n8m:b, 6n8n:b, 6n8o:b, 7n8b:AO, 7nac:O, 5ndg:M6, 5ndg:m6, 5ndv:M6, 5ndv:m6, 5ndw:M6, 5ndw:m6, 7nrc:LQ, 7nrd:LQ, 5obm:M6, 5obm:m6, 7of1:O, 7oh3:O, 7ohp:O, 7ohq:O, 7ohr:O, 7ohs:O, 7oht:O, 7ohu:O, 7ohv:O, 7ohw:O, 7ohx:O, 7ohy:O, 6oig:O, 5on6:w, 5on6:CQ, 7osa:uL13, 7osm:uL13, 8p8m:JW, 8p8n:JW, 8p8u:JW, 8pfr:JW, 6q8y:AU, 7r7a:O, 6r84:Q, 6r86:Q, 6r87:Q, 7rr5:LO, 6s47:AQ, 6snt:u, 6sv4:AU, 6sv4:XU, 6sv4:zU, 6t4q:LO, 5t62:b, 5t6r:b, 6t7i:LO, 6t7t:LO, 6t83:Oy, 6t83:Qa, 5tbw:w, 5tbw:CQ, 6tb3:AU, 5tga:M6, 5tga:m6, 5tgm:M6, 5tgm:m6, 6tnu:AU, 7too:AL16, 7top:AL16, 7u0h:O, 4u3m:M6, 4u3m:m6, 4u3n:M6, 4u3n:m6, 4u3u:M6, 4u3u:m6, 4u4n:M6, 4u4n:m6, 4u4o:M6, 4u4o:m6, 4u4q:M6, 4u4q:m6, 4u4r:M6, 4u4r:m6, 4u4u:M6, 4u4u:m6, 4u4y:M6, 4u4y:m6, 4u4z:M6, 4u4z:m6, 4u50:M6, 4u50:m6, 4u51:M6, 4u51:m6, 4u52:M6, 4u52:m6, 4u53:M6, 4u53:m6, 4u55:M6, 4u55:m6, 4u56:M6, 4u56:m6, 4u6f:M6, 4u6f:m6, 7ug6:O, 7uoo:O, 7uqb:O, 7uqz:O, 7v08:O, 4v4b:BM, 4v7f:J, 4v7r:BP, 4v7r:DP, 4v88:BO, 4v88:DO, 4v8t:O, 4v8y:BO, 4v8z:BO, 8v83:O, 8v84:O, 8v87:O, 4v91:O, 6woo:O, 6xiq:O, 6xir:O, 8y0u:LO, 6ylg:O, 6ylh:O, 6ylx:O, 6yly:O, 5z3g:S, 7z34:O, 6z6j:LO, 6z6k:LO, 7zpq:BN, 7zrs:BN, 7zs5:BP, 7zuw:BN, 7zux:EN, 7zw0:LR
10 8i9p:LO 204 169 0.4059 0.4020 0.4852 8.99e-49 8i9r:LO, 8i9t:LO, 8i9v:LO, 8i9w:LO, 8i9x:LO, 8i9y:LO, 8i9z:LO, 8ia0:LO, 7olc:LO, 7old:LO, 8oo0:LO, 8pv1:LO, 8pv2:LO, 8pv3:LO, 8pv4:LO, 8pv5:LO, 8pv6:LO, 8pv7:LO, 8pv8:LO, 8pvk:LO, 8pvl:LO, 7r81:Q1, 7z3n:LO, 7z3o:LO
11 5xxb:N 200 199 0.4010 0.4050 0.4070 9.00e-49
12 6qik:J 197 167 0.3960 0.4061 0.4790 1.13e-48 6qt0:J, 6qtz:J, 6ri5:J, 6rzz:J, 6s05:J
13 4v3p:LK 206 197 0.4109 0.4029 0.4213 7.50e-48 8ip8:FB, 8ipa:FB, 8ipb:FB, 8jiv:CO, 4v7e:CO
14 8c3a:w 199 199 0.4158 0.4221 0.4221 2.79e-47 8c3a:BJ, 8cq7:w, 8cq7:BJ, 8cqw:w, 8cqw:BJ, 8cre:w, 8cre:BJ, 8oeq:w, 8oeq:BJ, 7pzy:w, 7q08:w, 7q0f:w, 7q0p:w, 7q0r:w, 8q5i:w
15 9bh5:CO 201 197 0.4059 0.4080 0.4162 3.08e-46 9cai:CO
16 5xy3:O 196 195 0.4010 0.4133 0.4154 6.77e-46
17 8azw:d 205 185 0.3911 0.3854 0.4270 2.05e-45 8b2l:d3, 7qiw:Q, 7qiz:Q
18 4v7h:BM 178 143 0.3614 0.4101 0.5105 7.81e-42
19 6zj3:LW 208 176 0.3614 0.3510 0.4148 4.48e-41
20 8fru:O 196 198 0.3861 0.3980 0.3939 9.64e-41 8br8:LP, 8brm:LP, 8bsi:LP, 8bsj:LP, 8btd:LP, 8btr:LP, 7pwg:O, 7pwo:O2
21 4v8p:BI 198 201 0.4059 0.4141 0.4080 1.23e-40 4v8p:CI, 4v8p:EI, 4v8p:GI
22 3j79:K 201 196 0.3861 0.3881 0.3980 2.32e-40 3jbn:AK, 3jbo:AK, 3jbp:AK, 8tpu:AK, 5umd:K
23 6zu5:LO0 196 180 0.3267 0.3367 0.3667 2.58e-32
24 6rm3:LO0 173 158 0.2921 0.3410 0.3734 5.26e-31
25 8p5d:LO0 198 181 0.2723 0.2778 0.3039 5.09e-22 8p60:LO0, 8p60:KO0, 7qca:LO0
26 7qep:M6 196 168 0.2822 0.2908 0.3393 2.40e-21
27 6skf:BK 142 143 0.2376 0.3380 0.3357 6.90e-19 6skg:BK, 6th6:BK, 4v4n:AI, 4v6u:BI
28 4v9f:J 144 103 0.1832 0.2569 0.3592 2.19e-13 3cc2:J, 3cc4:J, 3cc7:J, 3cce:J, 3ccj:J, 3ccl:J, 3ccm:J, 3ccq:J, 3ccr:J, 3ccs:J, 3ccu:J, 3ccv:J, 3cd6:J, 3cma:J, 3cme:J, 3cpw:I, 3cxc:I, 1ffk:G, 3g4s:J, 3g6e:J, 3g71:J, 3i55:J, 3i56:J, 1jj2:I, 1k73:K, 1k8a:K, 1k9m:K, 1kc8:K, 1kd1:K, 1kqs:I, 1m1k:K, 1m90:K, 1n8r:K, 1nji:K, 2otj:J, 2otl:J, 3ow2:I, 1q7y:K, 1q81:K, 1q82:K, 1q86:K, 2qa4:J, 2qex:J, 1qvf:I, 1qvg:I, 1s72:J, 4v4p:AM, 4v4r:BN, 4v4s:BN, 4v4t:BN, 1vq4:J, 1vq5:J, 1vq6:J, 1vq7:J, 1vq8:J, 1vq9:J, 1vqk:J, 1vql:J, 1vqm:J, 1vqn:J, 1vqo:J, 1vqp:J, 1w2b:I, 1yhq:J, 1yi2:J, 1yij:J, 1yit:J, 1yj9:J, 1yjn:J, 1yjw:J
29 8hku:L13P 140 104 0.1832 0.2643 0.3558 2.49e-09 8hkv:L13P, 8hky:L13P, 8hkz:L13P, 8hl1:L13P, 8hl2:L13P, 8hl3:L13P, 8hl4:L13P, 8hl5:L13P
30 5myj:BM 147 105 0.1485 0.2041 0.2857 0.001
31 7jil:J 150 105 0.1485 0.2000 0.2857 0.002
32 7p7q:M 147 112 0.1485 0.2041 0.2679 0.006 7nhk:M, 6o8w:K, 6o8x:K, 6o8y:K, 6o8z:K, 6o90:K, 7p7r:M, 7p7s:M, 7p7t:M, 7p7u:M, 6w6p:K, 6wu9:K
33 7f0d:J 146 96 0.1436 0.1986 0.3021 0.008 7kgb:J, 7msc:J, 7msh:J, 7msm:J, 7msz:J, 7mt2:J, 7mt3:J, 7mt7:J, 7sfr:J, 5v7q:J, 5v93:J
34 7m4v:I 142 98 0.1386 0.1972 0.2857 0.013 7m4w:I, 7m4x:I, 7m4y:I, 7m4z:I, 7ryf:I, 7ryg:I, 7ryh:I, 7uvv:I, 7uvw:I, 7uvx:I, 7uvy:I, 7uvz:I, 7uw1:I, 6v39:I, 6v3a:I, 6v3b:I, 6v3d:I, 6yhs:F, 6ysi:F
35 5mmi:K 203 112 0.1386 0.1379 0.2500 0.021 6eri:AJ, 5h1s:L, 5mlc:L, 5mmm:K, 4v61:BL, 5x8p:K, 5x8t:K
36 7asm:H 145 112 0.1337 0.1862 0.2411 0.11 7asn:H, 7aso:M, 7asp:H, 6ddd:V, 6ddg:V, 6fxc:AH, 6fxc:BH, 5hkv:G, 5hl7:G, 6hma:H, 5li0:M, 5nd8:M, 5nd9:M, 5ngm:AH, 7nhl:M, 7nhm:M, 5nrg:G, 8p2f:M, 8p2g:M, 8p2h:M, 7p48:H, 6s0x:H, 6s0z:H, 6s12:H, 6s13:H, 6sj6:M, 5t7v:LM, 5tcu:LM, 7ttu:V, 7ttw:V, 4wce:G, 4wf9:G, 4wfa:G, 4wfb:G, 6wqn:V, 6wqq:V, 6wrs:V, 6wru:V, 8y36:H, 8y37:H, 8y38:H, 8y39:H, 6yef:M
37 5zeb:K 147 113 0.1535 0.2109 0.2743 0.18 6dzi:K, 6dzp:K, 8fr8:T, 8kab:K, 5o60:K, 5o61:K, 7s0s:L, 8v9j:L, 8v9k:L, 8v9l:L, 8whx:M, 8why:M, 8wi7:M, 8wi8:M, 8wib:M, 8wic:M, 7xam:K, 5xym:J, 8xz3:K, 7y41:K, 5zep:K, 5zet:K
38 9c4g:i 146 113 0.1535 0.2123 0.2743 0.38 8crx:i, 8cvm:i
39 8fmw:AL 145 95 0.1089 0.1517 0.2316 1.3 8fn2:L
40 3aj3:A 273 88 0.1139 0.0842 0.2614 2.0 4kep:A, 4keq:A
41 5h7e:A 182 40 0.0792 0.0879 0.4000 3.1
42 8i9p:Lf 108 67 0.0941 0.1759 0.2836 3.2 8i9r:Lf, 8i9t:Lf, 8i9v:Lf, 8i9w:Lf, 8i9x:Lf, 8i9y:Lf, 8i9z:Lf, 8ia0:Lf, 7olc:Lf, 7old:Lf, 8oo0:Lf, 8pv1:Lf, 8pv2:Lf, 8pv3:Lf, 8pv4:Lf, 8pv5:Lf, 8pv6:Lf, 8pv7:Lf, 8pv8:Lf, 8pvk:Lf, 8pvl:Lf, 7r81:h1, 7z3n:Lf, 7z3o:Lf
43 7fqi:A 265 57 0.0792 0.0604 0.2807 3.6 4aw9:A, 4awa:A, 4awb:A, 4awb:B, 7fqh:A, 7fqh:B, 7fqh:D, 7fqi:C, 7fqi:B, 7fqj:A, 7fqj:C, 7fqj:B, 7fqk:A, 7fqk:B, 7fqk:C, 7fqk:D, 7fql:A, 7fql:F, 7fql:B, 7fql:H, 7fql:C, 7fql:G, 7fql:D, 7fql:E, 5lu8:A, 5lu9:A, 5lua:B, 5lub:B, 7o50:A, 7o50:B
44 5vrb:B 646 57 0.0842 0.0263 0.2982 3.8 5vrb:D
45 5vrb:A 627 57 0.0842 0.0271 0.2982 3.9 5vrb:C
46 9cpo:A 930 37 0.0693 0.0151 0.3784 5.7
47 7ood:b 229 46 0.0743 0.0655 0.3261 7.3 7p6z:b, 7pah:b, 7pai:b, 7paj:b, 7pak:b, 7pal:b, 7pam:b, 7pan:b, 7pao:b, 7paq:b, 7par:b, 7pas:b, 7pat:b, 7pau:b, 7ph9:b, 7pha:b, 7phb:b, 7phc:b, 7pi8:b, 7pi9:b, 7pia:b, 7pib:b, 7pic:b, 7pio:b, 7pip:b, 7piq:b, 7pir:b, 7pis:b, 7pit:b
48 3sdi:F 242 95 0.1386 0.1157 0.2947 8.9 3mg6:F, 3mg7:F, 3mg8:F, 3oeu:F, 3oev:F, 3sdi:T, 3sdk:F
49 5juy:B 1234 61 0.0891 0.0146 0.2951 8.9 1cy5:A, 3j2t:A, 3j2t:B, 3j2t:C, 3j2t:D, 3j2t:E, 3j2t:F, 3j2t:G, 3jbt:A, 3jbt:C, 3jbt:E, 3jbt:G, 3jbt:I, 3jbt:K, 3jbt:M, 5juy:A, 5juy:C, 5juy:D, 5juy:E, 5juy:F, 5juy:G, 2p1h:A, 5wve:A, 5wve:C, 5wve:E, 5wve:G, 5wve:I, 5wve:K, 5wve:M, 1z6t:A, 1z6t:B, 1z6t:C, 1z6t:D
50 8x5v:A 892 55 0.0594 0.0135 0.2182 9.8

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218