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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
RNRREEILQSLALMLESSDGSQRITTAKLAASVGVSEAALYRHFPSKTRMFDSLIEFIEDSLITRINLILKDEKDTTARL
RLIVLLILGFGERNPGLTRILTGHALMFEQDRLQGRINQLFERIEVQLRQVMREKKMREGEGYTLDETLLASQLLAFCEG
MLSRFVRSEFKYRPTDDFEARWPLVAAQLQ

The query sequence (length=190) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 4gcl:B 196 190 0.9526 0.9235 0.9526 1.38e-125 4gck:A, 4gck:B, 4gck:C, 4gck:D, 4gcl:A, 4gcl:C, 4gcl:D, 4gcl:E, 4gcl:G, 4gcl:H, 4gcl:F, 5hbu:A, 5hbu:B, 5hbu:C, 5hbu:D, 5hbu:E, 5hbu:G, 5hbu:H, 5hbu:F, 5hsz:A, 5k58:E, 5k58:F, 5k58:A, 5k58:B
2 4gct:C 190 189 0.6684 0.6684 0.6720 5.24e-92 4gct:A, 4gct:B, 4gct:D, 5haw:A, 5haw:B
3 5dy0:A 220 73 0.1421 0.1227 0.3699 2.47e-06 5dy0:B, 5dy0:C, 5dy0:D, 5dy1:A, 5dy1:B, 6gy3:A, 6gy3:B
4 4w97:A 196 80 0.1316 0.1276 0.3125 0.001
5 7ju3:B 203 57 0.1053 0.0985 0.3509 0.002 8fw0:A, 8fw0:B, 8fw0:C, 8fw0:D, 8fw3:C, 8fw3:D, 8fw3:A, 8fw3:B, 8fw8:B, 8fw8:C, 8fw8:D, 7jnp:A, 7jnp:B, 7ju3:A, 8ssh:C, 8ssh:D, 8ssh:A, 8ssh:B
6 6o6n:A 195 84 0.1211 0.1179 0.2738 0.002 6o6p:A, 6o6p:B
7 7xaq:B 201 51 0.0947 0.0896 0.3529 0.004 8hjb:A, 7xaq:D, 7xaq:H, 7xaq:A, 7xaq:G, 7xaq:C
8 2vpr:A 197 55 0.1053 0.1015 0.3636 0.004
9 6g8g:A 195 54 0.1053 0.1026 0.3704 0.006 6g8g:B, 6g8g:C, 6g8g:D, 6g8h:CCC, 6g8h:BBB
10 2zoz:B 181 64 0.0947 0.0994 0.2812 0.008 2yve:A, 2yve:B, 2yvh:A, 2yvh:D, 2yvh:B, 2yvh:C, 2zoz:A
11 5fmp:A 184 138 0.2053 0.2120 0.2826 0.021 5aqc:A, 5aqc:B, 5cw8:A, 5cw8:B, 5cxi:A, 5cxi:B, 5fmp:B, 5ua1:B, 5ua1:A, 5ua2:A
12 7k1c:B 208 183 0.2263 0.2067 0.2350 0.027 7k1a:A, 7k1a:B, 7k1c:A, 7kd8:A, 7kd8:B, 7kd8:D, 7kd8:C, 2uxh:A, 2uxh:B, 2uxi:A, 2uxi:B, 2uxo:B, 2uxp:A, 2uxp:B, 2uxu:A, 2uxu:B
13 6yl2:B 192 106 0.1474 0.1458 0.2642 0.043 6yl2:A
14 8oo2:A 177 62 0.0947 0.1017 0.2903 0.045 8oo2:B
15 7eqf:A 184 46 0.0947 0.0978 0.3913 0.055 7eqf:B, 7eqf:C, 7eqf:D
16 6rxb:B 200 45 0.1000 0.0950 0.4222 0.11 6rxb:D, 6rxb:A, 6rxb:C
17 3qbm:A 199 92 0.1053 0.1005 0.2174 0.11 3qbm:B
18 4aux:A 207 54 0.1000 0.0918 0.3519 0.12 4abz:AAA, 4b1r:A, 4b3a:A, 4d7m:A, 4d7n:A, 2fj1:A, 3fk7:A, 3fk7:B, 5fkk:A, 5fkk:B, 5fkl:A, 5fkm:A, 5fkn:A, 5fkn:B, 5fko:A, 6fpl:A, 6fpm:A, 2o7o:A, 1ork:A, 6qjw:A, 6qjx:A, 1qpi:A, 6rbl:A, 6rbm:A, 6rcr:A, 6rgx:B, 2tct:A, 2trt:A, 4v2g:A, 4v2g:B, 2vke:A, 2vkv:A, 2x6o:A, 2x9d:A, 2xb5:A, 2xpu:A, 2xpv:A, 2xpw:A, 2xrl:A, 6yr1:AAA, 6yr2:AAA, 6yr2:BBB
19 3zqf:A 183 49 0.1000 0.1038 0.3878 0.14 6sy4:B, 6sy6:B
20 2y31:A 242 105 0.1368 0.1074 0.2476 0.16 2y30:A, 2y30:B, 2y31:B, 3zql:A, 3zql:B, 3zql:C, 3zql:D
21 3p9t:A 213 67 0.0842 0.0751 0.2388 0.18
22 3zqg:A 208 49 0.1000 0.0913 0.3878 0.20 4ac0:A, 2ns8:A, 2ns8:B, 2ns8:C, 2ns8:D, 6sy4:A, 6sy6:A, 3zqh:A, 3zqi:A, 3zqi:B
23 6ko7:C 186 79 0.1105 0.1129 0.2658 0.21 6ie8:A, 6ie9:A, 6ko7:A, 6ko7:B, 6ko7:D, 6ko9:A, 6ko9:B, 6ko9:C, 6ko9:D, 7n4w:A, 7n4z:A, 7n4z:C, 7n4z:B, 7n4z:D, 7n53:A, 7n53:B, 7n54:A, 7n54:B, 7n54:C, 7n54:D, 3vvy:A, 3vvy:B, 3vvy:C, 3vvy:D, 3vvz:A, 3vvz:B, 3vvz:C, 3vvz:D, 3vw0:B, 3vw0:D, 3vw1:B, 3vw1:D, 3vw2:A, 3vw2:B, 3vw2:C, 3vw2:D
24 6srn:A 187 53 0.0842 0.0856 0.3019 0.22
25 4gl8:A 500 34 0.0737 0.0280 0.4118 0.26 4gl8:B
26 5gpc:A 190 73 0.0789 0.0789 0.2055 0.41 5gpc:B, 5gpc:C, 5gpc:D
27 6ayh:A 192 162 0.1947 0.1927 0.2284 0.68
28 5h58:B 204 38 0.0632 0.0588 0.3158 1.2 5h58:A, 5h58:C, 5h58:D, 4pxi:A, 4pxi:B, 4pxi:C, 4pxi:D
29 3whc:A 190 68 0.0789 0.0789 0.2206 2.1 1vi0:A, 1vi0:B, 3whb:A, 3whb:B, 3whc:B, 3whc:C, 3whc:D, 3whc:E, 3whc:F
30 6wi7:A 206 40 0.0632 0.0583 0.3000 3.9 2ckl:A, 8grm:M, 2h0d:A, 7nd1:H, 8pp7:K, 8pp7:M, 4r8p:K, 4r8p:M, 3rpg:B, 6wi8:A, 6wi8:B
31 6ayi:A 183 65 0.1000 0.1038 0.2923 4.1 6ayi:B, 6ayi:C, 6ayi:D
32 6frk:r 195 72 0.1053 0.1026 0.2778 4.3 5m72:A, 5wrv:B
33 8ppt:B 1191 53 0.0895 0.0143 0.3208 4.5 8ppu:B, 8ppv:B, 6t8h:B
34 8e29:A 692 23 0.0579 0.0159 0.4783 5.5 8e28:A, 8e2a:A, 4pmw:A, 4pmw:B
35 2eh3:A 171 45 0.0632 0.0702 0.2667 5.6
36 5vl9:C 191 45 0.0737 0.0733 0.3111 5.6 5vl9:B, 5vl9:A, 5vl9:D, 5vlg:A, 5vlg:B, 5vlg:C, 5vlg:D, 5vlg:E, 5vlg:F, 5vlg:G, 5vlg:H, 5vlm:A, 5vlm:B, 5vlm:C, 5vlm:D, 5vlm:E, 5vlm:F, 5vlm:G, 5vlm:H
37 5mru:A 173 45 0.1000 0.1098 0.4222 6.7
38 6knb:B 1120 58 0.0842 0.0143 0.2759 7.4 6knc:B
39 7odx:A 350 74 0.1211 0.0657 0.3108 7.4
40 2boy:A 253 33 0.0526 0.0395 0.3030 8.4 2boy:B, 2boy:C, 2boy:D, 2boy:E, 2boy:F, 2boy:G, 2boy:H
41 3lsj:A 205 70 0.0632 0.0585 0.1714 9.0 3lsj:B, 3lsp:A, 3lsr:A
42 2np5:A 187 40 0.0684 0.0695 0.3250 9.4

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218