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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
RNHDVLSRMISEKAALHGLLNCLIKEFAIPEGYLRYEWPDEMKGIPPGAYFDGADWKGIPMMIGLPDQLQLFVMVDRRDT
FGSQHYLSDVYLRQAQGDWQCPDFEPLVARLLAACEHIAGRKNPELYEQILQSQRLVSAIVSHNGRQRADAPLQHYLQSE
QGLWFGHPSHPAPKARLWPHLGQEQWAPEFQARAALHQFEVPVDGLHIGANGLTPQQVLDGFADQQPASPGHAIICMHPV
QAQLFMQDARVQQLLRDNVIRDLGQSGRVASPTASIRTWFIDDHDYFIKGSLNVRITNCVRKNAWYELESTVLIDRLFRQ
LLDQHADTLGGLVAAAEPGVVSWSPAAAGELDSHWFREQTGGILRENFCRRTGAERSIMAGTLFARGVDLQPMIQTFLRT
HYGEALDDNALLYWFDDYQTRLLRPVLSLFFNHGVVMEPHLQNSVLVHQQGRPQQVLLRDFEGVKLTDDLGIRYIDDDIH
PRVRQSLLYSREQGWNRIMYCLFINHLSETILALSQGRPQLAPLMWRRVQQQLRAIQGELKQPSPELDALIAGHPVACKT
NLKVRLAAASYVRLPSPW

The query sequence (length=578) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 2x3j:A 586 584 1.0000 0.9863 0.9897 0.0 2w02:A, 2w02:B, 2w03:A, 2w03:B, 2w04:B, 2x3j:B, 2x3k:A, 2x3k:B
2 5jm8:A 556 407 0.1817 0.1888 0.2580 1.20e-13 5jm8:B, 5jm8:C, 5jm8:D, 5jm8:E, 5jm8:F, 5jm8:G, 5jm8:H
3 3to3:B 595 334 0.1367 0.1328 0.2365 2.87e-09
4 2x0q:A 582 199 0.0830 0.0825 0.2412 3.19e-04 2x0p:A
5 7tgk:D 593 331 0.1280 0.1248 0.2236 0.023 7tgk:B, 7tgk:E, 7tgk:A, 7tgk:C, 7tgl:A, 7tgl:B, 7tgl:C, 7tgl:D, 7tgl:E, 7tgm:A, 7tgm:B, 7tgm:C, 7tgm:E, 7tgm:D
6 7cbb:A 576 63 0.0346 0.0347 0.3175 0.044 7cbb:B
7 7tgn:B 576 320 0.1125 0.1128 0.2031 0.33 7tgn:A, 7tgn:C, 7tgn:D
8 6kpm:A 295 54 0.0242 0.0475 0.2593 1.0 6kpn:A, 6kpo:A
9 1jjv:A 194 64 0.0381 0.1134 0.3438 3.0
10 7jj9:A 461 74 0.0381 0.0477 0.2973 3.6 7jj8:B, 7jj8:A, 7jj8:C, 7jj8:D, 7jja:A, 7jjb:A
11 7obr:x 488 60 0.0242 0.0287 0.2333 6.1 2go5:W, 2j37:W, 5l3q:A, 5l3q:C, 1mfq:C, 7nfx:x, 7qwq:x, 1ry1:W, 4ue5:D, 6y2z:A, 6y32:A, 6y32:C, 6y32:E, 6y32:G
12 7vua:A 785 85 0.0346 0.0255 0.2353 6.8 7vua:B
13 3jaj:z 426 60 0.0242 0.0329 0.2333 7.2 6frk:x, 3jan:z, 7obq:x, 6r6g:AB

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218