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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
RKGIILAGGSGTRLYPVTMAVSKQLLPIYDKPMIYYPLSTLMLAGIRDILIISTPQDTPRFQQLLGDGSQWGLNLQYKVD
PSPDGLAQAFIIGEEFIGHDDCALVLGDNIFYGHDLPKLMEAAVNKSGATVFAYHVNDPERYGVVEFDGTAVSLEEKPPK
SNYAVTGLYFYDNSVVEMAKNLKPSLEITDINRIYMEQGRLSVAMMGRGYAWLDTGTHQSLIEASNFIATIEERQGLKVS
CPEEIAFRKNFINAQQVIELAGPLSKNDYGKYLLKMVK

The query sequence (length=278) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 1h5s:B 291 287 0.9281 0.8866 0.8990 0.0 1h5r:A, 1h5r:B, 1h5r:C, 1h5r:D, 1h5s:A, 1h5s:D, 1h5s:C, 1h5t:A, 1h5t:D, 1h5t:B, 1h5t:C, 1iim:A, 1iim:B, 1iin:A, 1iin:B, 1iin:C, 1iin:D, 1mp3:A, 1mp3:B, 1mp4:A, 1mp4:B, 1mp5:A, 1mp5:B, 1mp5:C, 1mp5:D, 3pkp:A, 3pkp:B, 3pkp:C, 3pkp:D, 3pkp:I, 3pkp:J, 3pkp:K, 3pkp:L, 3pkq:A, 3pkq:B, 3pkq:C, 3pkq:D
2 4b2x:B 302 286 0.7518 0.6921 0.7308 2.72e-154 4arw:A, 4arw:B, 4arw:C, 4arw:D, 4asj:A, 4asj:B, 4asj:C, 4asj:D, 4asy:A, 4asy:B, 4asy:C, 4asy:D, 4b2w:A, 4b2w:B, 4b2w:C, 4b2w:D, 4b2x:A, 4b2x:C, 4b2x:D, 4b3u:A, 4b3u:B, 4b3u:C, 4b3u:D, 4b42:A, 4b42:B, 4b42:C, 4b42:D, 4b4b:A, 4b4b:B, 4b4b:C, 4b4b:D, 4b4g:A, 4b4g:B, 4b4g:C, 4b4g:D, 4b4m:A, 4b4m:B, 4b4m:C, 4b4m:D, 4b5b:A, 4b5b:B, 4b5b:C, 4b5b:D, 5fts:A, 5fts:B, 5fts:C, 5fts:D, 5ftv:A, 5ftv:B, 5ftv:C, 5ftv:D, 5fu0:A, 5fu0:B, 5fu0:C, 5fu0:D, 5fu8:A, 5fu8:B, 5fu8:C, 5fu8:D, 5fuh:A, 5fuh:B, 5fuh:C, 5fuh:D, 1fxo:A, 1fxo:C, 1fxo:B, 1fxo:D, 1fxo:E, 1fxo:H, 1fxo:F, 1fxo:G, 5fye:A, 5fye:B, 5fye:C, 5fye:D, 1g0r:A, 1g0r:B, 1g0r:C, 1g0r:D, 1g0r:E, 1g0r:G, 1g0r:H, 1g1l:A, 1g1l:C, 1g1l:B, 1g1l:D, 1g1l:E, 1g1l:H, 1g1l:F, 1g1l:G, 1g23:A, 1g23:B, 1g23:C, 1g23:D, 1g23:E, 1g23:F, 1g23:G, 1g23:H, 1g2v:A, 1g2v:C, 1g2v:B, 1g2v:D, 1g2v:E, 1g2v:G, 1g2v:F, 1g2v:H, 1g3l:A, 1g3l:C, 1g3l:B, 1g3l:D, 6t37:A, 6t37:B, 6t37:C, 6t37:D, 6t38:A, 6t38:B, 6t38:C, 6t38:D, 6tqg:A, 6tqg:B, 6tqg:C, 6tqg:D, 3zlk:A, 3zlk:B, 3zlk:C, 3zlk:D, 3zll:A, 3zll:B, 3zll:C, 3zll:D
3 6n0u:A 295 286 0.7338 0.6915 0.7133 3.72e-151 6n0u:B, 6n0u:C, 6n0u:D
4 5ify:A 293 286 0.7194 0.6826 0.6993 5.60e-150 5ify:B, 5ify:C, 5ify:D, 5ify:E, 5ify:F
5 4ho9:A 294 284 0.6942 0.6565 0.6796 3.24e-142 4ho3:A, 4ho4:A, 4ho5:A, 4ho5:B, 4ho6:A, 4ho8:A, 4ho8:B, 4ho8:C, 4ho8:D, 4ho9:B, 4hoc:A, 4hoc:B
6 1mc3:A 291 286 0.6547 0.6254 0.6364 1.35e-128 1mc3:B
7 1lvw:A 295 286 0.6151 0.5797 0.5979 1.29e-122 1lvw:B, 1lvw:C, 1lvw:D
8 6b5e:B 286 285 0.6043 0.5874 0.5895 2.48e-120 6b5e:A, 6b5e:C, 6b5e:D, 6b5e:E, 6b5e:F, 6b5e:G, 6b5e:H, 6b5k:A, 6b5k:B
9 3hl3:A 246 231 0.3669 0.4146 0.4416 4.28e-56 4ecm:A
10 3juk:A 265 259 0.2590 0.2717 0.2780 3.11e-18 3juk:B, 3juk:C, 3juk:D
11 2ggq:A 401 271 0.2482 0.1721 0.2546 3.04e-15 5z09:A, 5z09:B, 5z09:C, 5z09:D
12 7whs:A 366 228 0.2014 0.1530 0.2456 5.64e-14 7whs:B, 7whs:C, 7whs:D, 7whs:E, 7whs:F, 7wht:A, 7wht:B, 7wht:C, 7wht:D, 7wht:E, 7wht:F
13 4y7u:A 224 230 0.2194 0.2723 0.2652 5.56e-13 4y7v:A
14 7x8k:B 367 229 0.2050 0.1553 0.2489 1.15e-12 7x8k:A, 7x8k:D
15 5ve7:A 282 262 0.2230 0.2199 0.2366 1.18e-12
16 8b6d:A 291 247 0.2086 0.1993 0.2348 1.27e-12 8b68:A, 8b6d:B
17 8f73:E 281 276 0.2446 0.2420 0.2464 1.34e-12 8f73:A, 8f73:B, 8f73:C, 8f73:D, 8f73:F, 8f73:G, 8f73:H
18 2ux8:G 288 267 0.2482 0.2396 0.2584 1.07e-11 2ux8:B, 2ux8:C, 2ux8:D, 2ux8:E, 2ux8:F
19 7d72:K 360 242 0.1906 0.1472 0.2190 9.77e-11 7d72:I, 7d72:E, 7d72:F, 7d72:G, 7d72:H, 7d72:J, 7d72:L, 7d73:E, 7d73:F, 7d73:G, 7d73:I, 7d73:J, 7d73:K, 7d73:L, 7d73:H, 7d74:E, 7d74:F, 7d74:G, 7d74:H, 7d74:I, 7d74:J, 7d74:K, 7d74:L
20 6k8d:A 290 221 0.1799 0.1724 0.2262 2.03e-10 6ikz:B, 6k8d:B, 6k8d:C, 6k8d:D, 6knj:A, 6knj:B, 6knl:A, 6knl:B
21 5i1f:A 290 228 0.1906 0.1828 0.2325 1.42e-09
22 2ux8:A 255 250 0.2266 0.2471 0.2520 1.98e-09 2ux8:H
23 1jyl:A 228 51 0.0899 0.1096 0.4902 1.63e-06 1jyl:B, 1jyl:C, 1jyl:D
24 2pa4:B 299 237 0.1906 0.1773 0.2236 1.08e-05 2pa4:A, 2pa4:C, 2pa4:D
25 4jd0:A 245 218 0.1799 0.2041 0.2294 2.84e-05
26 7d72:A 407 237 0.2050 0.1400 0.2405 1.27e-04 7d72:B, 7d72:C, 7d72:D, 7d73:A, 7d73:B, 7d73:C, 7d73:D, 7d74:A, 7d74:D, 7d74:B, 7d74:C
27 6jly:E 414 66 0.0863 0.0580 0.3636 2.49e-04 6jly:F, 6jlz:E, 6jlz:F
28 1wvc:A 254 52 0.0683 0.0748 0.3654 8.02e-04 1tzf:A
29 6jq8:A 225 188 0.1583 0.1956 0.2340 8.62e-04
30 5l6v:I 400 187 0.1691 0.1175 0.2513 0.001
31 6jlz:I 430 72 0.0647 0.0419 0.2500 0.006
32 6r8u:A 425 278 0.2410 0.1576 0.2410 0.010 5l6s:C, 5l6s:G, 5l6s:I, 5l6s:L, 5l6v:A, 5l6v:E, 5l6v:G, 5l6v:H, 5l6v:J, 5l6v:K, 5l6v:N, 5l6v:B, 5l6v:C, 5l6v:D, 5l6v:F, 5l6v:L, 5l6v:M, 5l6v:O, 5l6v:P, 6r8b:D, 6r8b:B, 6r8b:A, 6r8b:C, 6r8u:B, 6r8u:D, 6r8u:C, 6shj:D, 6shj:A, 6shj:B, 6shj:C, 6shn:D, 6shn:C, 6shq:A, 6shq:D, 6shq:C, 6shq:B, 6si8:A, 6si8:B, 6si8:D, 6si8:C
33 7v1l:B 221 81 0.0755 0.0950 0.2593 0.011 7v6p:A
34 4fce:A 441 195 0.1655 0.1043 0.2359 0.013
35 4e1k:A 450 157 0.1475 0.0911 0.2611 0.015 4knr:A, 4knx:A, 4kpx:A, 4kpz:A, 4kql:A, 2v0i:A, 2v0j:A, 2v0k:A, 2v0l:A, 2vd4:A, 2w0v:A, 2w0w:A
36 6xhq:A 237 52 0.0719 0.0844 0.3846 0.026 6xhq:B, 6xhs:B, 6xhs:E, 6xht:A, 6xht:B, 6xht:E, 6xht:F
37 3rsb:B 185 66 0.0683 0.1027 0.2879 0.058 3rsb:A, 3rsb:C, 3rsb:D
38 2x65:A 334 108 0.0971 0.0808 0.2500 0.073 2x5z:A, 2x5z:B, 2x60:A, 2x60:B, 2x65:B
39 1vpa:A 221 55 0.0683 0.0860 0.3455 0.10 1vpa:B
40 6pd2:C 616 51 0.0612 0.0276 0.3333 0.86 6pd1:A, 6pd1:B, 6pd1:D, 6pd2:A, 6pd2:B, 6pd2:D
41 1tmo:A 794 146 0.1367 0.0479 0.2603 1.8
42 1i6n:A 278 71 0.0647 0.0647 0.2535 1.8
43 5tew:A 333 21 0.0396 0.0330 0.5238 2.0
44 6y66:GGG 268 81 0.0791 0.0821 0.2716 3.2 6y66:AAA, 6y66:BBB, 6y66:CCC, 6y66:DDD, 6y66:EEE, 6y66:FFF, 6y66:HHH, 6y66:III, 6y66:JJJ
45 7asn:S 103 66 0.0683 0.1845 0.2879 5.1 7asm:S, 7aso:Z, 7asp:S, 6ddd:G, 6ddg:G, 6fxc:AS, 6fxc:BS, 5hkv:R, 5hl7:R, 6hma:S, 5ngm:AS, 7nhl:X, 7nhm:X, 5nrg:R, 8p2f:X, 8p2g:X, 8p2h:X, 7p48:S, 6s0x:S, 6s0z:S, 6s12:S, 6s13:S, 6sj6:X, 5t7v:L7, 5tcu:L7, 7ttu:G, 7ttw:G, 4wce:R, 4wf9:R, 4wfa:R, 4wfb:R, 6wqn:G, 6wqq:G, 6wrs:G, 8y36:S, 8y37:S, 8y38:S, 8y39:S
46 6wru:G 89 57 0.0683 0.2135 0.3333 5.2 5li0:X, 5nd8:X, 5nd9:X, 6yef:X
47 4v2i:A 315 57 0.0719 0.0635 0.3509 6.4 4v2i:B
48 8chd:A 461 59 0.0612 0.0369 0.2881 6.9 8chd:B
49 5mog:B 472 59 0.0647 0.0381 0.3051 8.7 5mog:A, 5mog:C, 5mog:D, 5mog:E
50 7b0n:I 191 19 0.0324 0.0471 0.4737 8.9 6gcs:I, 7o6y:I, 7o71:I, 6rfq:I, 6rfr:I, 6rfs:I, 6y79:I, 6yj4:I
51 6od3:A 62 24 0.0360 0.1613 0.4167 8.9 6od3:B, 6od3:H, 6od3:E, 6od3:F, 6od4:A, 6od4:B, 6od5:A, 6od5:B, 6od5:C, 6od5:D, 8osb:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218