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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
RIELRSDITVELVDSSASDLAVVKAARVSTDGGSTRGLIRYLMRSRHGSPFEHNSMTFLVRAPIFTVRHLMRHRTWSFNE
ESARYREVGAAFYVPDATRLLRQEGKPGDYRYVGGSTDDHQQVVRSATRAYEVAFEEYQRLLDSGIAREIARLVLPVSTY
SVLYATCNARALMHFLSLRTHRPDAAYVSHPQREIEMVAEQMETAWAKLMPVTHEAFTAFGRVSP

The query sequence (length=225) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 4p5b:B 235 235 1.0000 0.9574 0.9574 1.42e-164 4p5a:A, 4p5a:B, 4p5a:C, 4p5a:D, 4p5b:A, 4p5b:C, 4p5b:D
2 1o26:B 221 226 0.3911 0.3982 0.3894 2.05e-42 5chp:A, 3g4a:A, 3g4a:D, 3g4a:C, 3g4a:B, 3g4c:A, 3g4c:D, 3g4c:C, 3g4c:B, 4gt9:A, 4gta:A, 4gtb:A, 4gtc:A, 4gtc:C, 4gtc:B, 4gtc:D, 4gtd:A, 4gtd:D, 4gtd:C, 4gtd:B, 4gte:A, 4gte:C, 4gte:B, 4gte:D, 4gtf:A, 4gtl:B, 4gtl:D, 4gtl:A, 4gtl:C, 5ioq:A, 5ioq:B, 5ioq:C, 5ioq:D, 5ior:A, 5ios:A, 5ios:B, 5ios:C, 5ios:D, 5iot:A, 5iot:B, 5iot:D, 5iot:C, 5jfe:A, 4kar:A, 4kar:C, 4kar:B, 4kar:D, 4kas:A, 4kas:D, 4kas:B, 4kas:C, 4kat:A, 4kat:D, 4kat:C, 4kat:B, 1kq4:A, 1kq4:C, 1kq4:D, 1kq4:B, 3n0b:A, 3n0b:D, 3n0b:C, 3n0b:B, 3n0c:A, 3n0c:D, 3n0c:C, 3n0c:B, 7ndw:A, 7ndw:C, 7ndw:D, 7ndw:B, 7ndz:A, 7ndz:C, 7ndz:D, 7ndz:B, 1o25:A, 1o25:D, 1o25:B, 1o25:C, 1o26:A, 1o26:D, 1o26:C, 1o27:A, 1o27:D, 1o27:C, 1o27:B, 1o28:A, 1o28:D, 1o28:B, 1o28:C, 1o29:A, 1o29:D, 1o29:C, 1o29:B, 1o2a:A, 1o2a:C, 1o2a:D, 1o2a:B, 1o2b:A, 1o2b:C, 1o2b:D, 1o2b:B
3 6j61:A 242 205 0.3556 0.3306 0.3902 1.88e-32 6j61:B, 6j61:D, 6j61:C
4 4fzb:C 207 176 0.2311 0.2512 0.2955 9.98e-16 4fzb:A, 4fzb:D, 4fzb:B, 4fzb:E, 4fzb:G, 4fzb:F, 4fzb:I, 4fzb:K, 4fzb:L, 4fzb:M, 4fzb:O, 4fzb:P
5 2cfa:A 180 173 0.2044 0.2556 0.2659 1.47e-11 2cfa:B, 4fzb:H, 4fzb:J, 4fzb:N
6 2af6:G 246 153 0.1956 0.1789 0.2876 4.20e-07 2af6:A, 2af6:B, 2af6:D, 2af6:C, 2af6:E, 2af6:F, 2af6:H, 2gq2:A, 2gq2:C, 2gq2:D, 2gq2:B, 3gwc:A, 3gwc:B, 3gwc:D, 3gwc:C, 3gwc:E, 3gwc:F, 3gwc:H, 3gwc:G, 3hzg:A, 3hzg:B, 3hzg:D, 3hzg:C
7 3fnn:A 227 151 0.1689 0.1674 0.2517 0.019
8 3ah5:A 215 160 0.2089 0.2186 0.2938 0.083 3ah5:C, 3ah5:B, 3ah5:D, 3ah5:E, 3ah5:F, 3n3y:A, 3n3y:B, 3n3y:C, 3n3y:D
9 6bza:C 501 73 0.1022 0.0459 0.3151 1.2 6bza:A, 6bza:B, 6bzn:D, 6bzq:A, 6bzq:B, 6bzq:C, 6bzq:D, 6bzt:A, 6bzt:B, 6bzt:C, 6bzt:D, 6bzz:A, 6bzz:B, 6bzz:C, 6bzz:D
10 2z5x:A 513 104 0.1111 0.0487 0.2404 2.1 2bxr:A, 2bxr:B, 2bxs:A, 2bxs:B, 2z5y:A
11 1o5w:C 512 78 0.0800 0.0352 0.2308 2.7 1o5w:A, 1o5w:B, 1o5w:D
12 3l2k:A 352 104 0.1333 0.0852 0.2885 3.4 3l2k:B
13 8hc0:A 360 28 0.0578 0.0361 0.4643 3.7
14 1mpy:A 307 44 0.0667 0.0489 0.3409 5.6 1mpy:B, 1mpy:C, 1mpy:D
15 3ps9:A 668 55 0.0711 0.0240 0.2909 6.5 3awi:A, 3awi:B, 3awi:C, 3awi:D, 3awi:E, 3awi:F
16 3sao:A 150 42 0.0756 0.1133 0.4048 6.5 3sao:B
17 4yd9:B 825 38 0.0533 0.0145 0.3158 7.4 4yd9:E, 4yd9:H, 4yd9:K, 4yd9:N, 4yd9:Q, 4yd9:T, 4yd9:W, 4yd9:Z, 4yd9:c

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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