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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
RHMASIEKVANCIRCLAADIVQGGKSGHPGTPMGMAPMSAVLWTEVMKYNSQDPDWVDRDRFVMSNGHGCALQYALLHMA
GYNLTMDDLKGFRQDGSRTPGHPERFVTPGVEVTTGPLGQGIANAVGLAIAEAHLAATFNRPGYNIVDHYTYVYCGDGCL
MEGVCQEALSLAGHLALEKLIVIYDSNYISIDGSTSLSFTEQCHQKYVAMGFHVIEVKNGDTDYEGLRKALAEAKATKGK
PKMIVQTTTIGFGSSKQGTEKVHGAPLGEEDIANIKAKFGRDPQKKYDVDDDVRAVFRMHIDKCSAEQKAWEELLAKYTA
AFPAEGAAFVAQMRGELPSGWEAKLPTNSSAIATRKASENCLAVLFPAIPALMGGSADLTPSNLTRPASANLVDFSSSSK
EGRYIRFGVREHAMCAILNGLDAHDGIIPFGGTFLNFIGYALGAVRLAAISHHRVIYVATHDSIGVGEDGPTHQPVELVA
ALRAMPNLQVIRPSDQTETSGAWAVALSSIHTPTVLCLSRQNTEPQSGSSIEGVRHGAYSVVDVPDLQLVIVASGSEVSL
AVDAAKALSGELRVRVVSMPCQELFDAQPDTYRQAVLPAGVPVVSVEAYVSFGWEKYSHAHVGMSGFGASAPAGVLYKKF
GITVEEVVRTGRELAKRFPDGTAPLKNSSFS

The query sequence (length=671) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 1r9j:B 671 671 1.0000 1.0000 1.0000 0.0 1r9j:A
2 1ay0:A 678 664 0.5142 0.5088 0.5196 0.0 1ay0:B, 1gpu:A, 1gpu:B, 1ngs:A, 1ngs:B, 1tka:A, 1tka:B, 1tkb:A, 1tkb:B, 1tkc:A, 1tkc:B, 1trk:A, 1trk:B
3 5hje:A 676 677 0.5007 0.4970 0.4963 0.0 5hyv:A, 5i51:A, 5i5e:A, 5i5g:A, 5xps:A, 5xqa:A, 5xqk:A, 5xrv:A, 5xry:A, 5xs6:A, 5xsa:A, 5xsb:A, 5xsm:A, 5xt0:A, 5xt4:A, 5xtl:A, 5xtv:A, 5xtx:A, 5xu2:A, 5xu9:A, 5xuf:A, 5xvt:A
4 5nd5:A 669 664 0.5142 0.5157 0.5196 0.0 5nd5:B
5 8ci0:AAA 666 665 0.4978 0.5015 0.5023 0.0 8ci0:BBB, 8ci0:CCC, 1itz:A, 1itz:B, 1itz:C
6 7wrr:A 650 638 0.4993 0.5154 0.5251 0.0 7wrr:B, 7wrr:C, 7wrr:D, 7wrt:A, 7wrt:B, 7wrt:C, 7wrt:D
7 8r3p:A 672 664 0.4888 0.4881 0.4940 0.0 8r3p:B, 8r3p:C, 8r3p:D
8 8cip:A 665 665 0.4844 0.4887 0.4887 0.0 8cip:B, 8cip:C, 8cip:D
9 8r3o:B 667 667 0.4799 0.4828 0.4828 0.0 8r3o:A, 8r3o:C, 8r3o:D
10 5hht:B 667 667 0.4709 0.4738 0.4738 0.0 5hht:A, 1qgd:A, 1qgd:B, 2r5n:A, 2r5n:B, 2r8o:A, 2r8o:B, 2r8p:A, 2r8p:B, 6rjc:A, 6rjc:B, 6tj8:A, 6tj8:B, 6tj9:A, 6tj9:B, 8wa7:A, 8wa7:B
11 3m49:A 665 665 0.4724 0.4767 0.4767 0.0 3hyl:A, 3hyl:B, 3m49:B
12 5vrb:B 646 655 0.4769 0.4954 0.4885 0.0 5vrb:D
13 8qmf:A 678 662 0.4635 0.4587 0.4698 0.0 8qmf:B
14 8r3q:D 676 653 0.4158 0.4127 0.4273 0.0 8r3q:B, 8r3q:A, 8r3q:C
15 8r3r:A 658 656 0.4620 0.4711 0.4726 0.0 8r3r:B, 8r3r:C, 8r3r:D
16 8r3s:A 663 653 0.4441 0.4495 0.4564 0.0 8r3s:B, 8r3s:C, 8r3s:D, 8r3s:E, 8r3s:F, 8r3s:G, 8r3s:H, 8r3s:I, 8r3s:J
17 5vrb:A 627 657 0.4620 0.4944 0.4718 0.0 5vrb:C
18 4c7x:A 662 651 0.4486 0.4547 0.4624 0.0
19 3upt:A 671 676 0.4635 0.4635 0.4601 0.0 3upt:B
20 4xeu:A 632 667 0.4188 0.4446 0.4213 1.04e-170
21 3rim:A 694 663 0.4188 0.4049 0.4238 3.04e-156 3rim:C, 3rim:B, 3rim:D
22 3m34:A 632 647 0.3905 0.4146 0.4049 1.90e-151 3m6l:A, 3m7i:A
23 6rjb:B 622 592 0.2489 0.2685 0.2821 4.01e-42 6ha3:A, 6had:A, 4kxu:A, 4kxv:A, 4kxw:A, 4kxx:A, 4kxy:A, 4kxy:B, 3mos:A, 3ooy:A, 3ooy:B, 6rjb:A, 8wa8:A, 8wa9:A, 8wa9:B, 8waa:A, 8waa:B
24 6yak:AAA 282 271 0.1371 0.3262 0.3395 4.15e-33 6yak:CCC
25 6yak:DDD 311 314 0.1416 0.3055 0.3025 1.36e-15 6yak:BBB
26 6ouv:A 595 182 0.0745 0.0840 0.2747 3.60e-05 2o1x:A, 2o1x:B, 6ouv:B, 8v9i:A, 8v9i:B
27 6ouv:A 595 133 0.0551 0.0622 0.2782 0.40 2o1x:A, 2o1x:B, 6ouv:B, 8v9i:A, 8v9i:B
28 6xxg:AAA 560 182 0.0745 0.0893 0.2747 4.27e-05 6ouw:A
29 6xxg:AAA 560 157 0.0596 0.0714 0.2548 0.36 6ouw:A
30 6xxg:BBB 539 182 0.0745 0.0928 0.2747 4.34e-05 2o1x:C, 2o1x:D
31 6xxg:BBB 539 129 0.0507 0.0631 0.2636 0.76 2o1x:C, 2o1x:D
32 8a45:F 573 110 0.0492 0.0576 0.3000 1.88e-04 8a29:A, 8a29:B, 8a29:C, 8a29:D, 8a29:E, 8a29:F, 8a45:A, 8a45:B, 8a45:C, 8a45:D, 8a45:E, 8a4d:A, 8a4d:B, 8a4d:C, 8a4d:D, 8a4d:E, 8a4d:F, 8a5k:A, 8a5k:B, 8a5k:C, 8a5k:D, 8a5k:E, 8a5k:F
33 2g28:B 801 201 0.0775 0.0649 0.2587 0.001 2g28:A, 2iea:A, 2iea:B, 1l8a:B, 1l8a:A, 3lpl:A, 3lpl:B, 3lq2:A, 3lq2:B, 3lq4:A, 3lq4:B, 2qta:A, 2qta:B, 2qtc:A, 2qtc:B, 1rp7:A, 1rp7:B
34 2g25:B 831 201 0.0775 0.0626 0.2587 0.002 2g25:A
35 7z5n:H 307 58 0.0343 0.0749 0.3966 0.008
36 2o1s:A 536 238 0.0849 0.1063 0.2395 0.027 2o1s:C
37 8bzx:A 546 164 0.0656 0.0806 0.2683 0.066
38 2o1s:B 493 184 0.0671 0.0913 0.2446 0.067 2o1s:D
39 8a9c:B 520 110 0.0477 0.0615 0.2909 0.11
40 8bzx:B 568 110 0.0477 0.0563 0.2909 0.11
41 5a4e:B 323 57 0.0328 0.0681 0.3860 0.13 6eif:C
42 4aze:A 350 57 0.0328 0.0629 0.3860 0.14 6a1f:A, 6a1g:A, 6a1g:B, 5a3x:A, 5a3x:B, 5a3x:C, 5a3x:D, 5a4e:A, 5a4e:C, 5a4e:D, 5a4l:A, 5a4l:B, 5a4l:C, 5a4l:D, 5a4q:A, 5a4q:B, 5a4q:C, 5a4q:D, 5a4t:A, 5a4t:B, 5a4t:C, 5a4t:D, 7a4o:A, 7a4o:B, 7a4r:A, 7a4r:B, 7a4w:A, 7a4w:B, 7a4z:A, 5a54:A, 5a54:B, 5a54:C, 5a54:D, 7a51:A, 7a52:A, 7a52:B, 7a53:A, 7a53:B, 7a55:A, 7a55:B, 7a5b:A, 7a5b:B, 7a5d:A, 7a5l:A, 7a5n:A, 7a5n:B, 5aik:A, 5aik:B, 5aik:C, 5aik:D, 7aj2:A, 7aj4:A, 7aj5:A, 7aj7:A, 7aj8:A, 7aja:A, 7ajm:A, 7ajm:B, 7ajs:A, 7ajs:B, 7ajv:A, 7ajv:B, 7ajw:A, 7ajy:A, 7ajy:B, 7ak2:A, 7ak2:B, 7aka:A, 7aka:B, 7akb:A, 7akb:B, 7ake:A, 7ake:B, 7akl:A, 3anq:A, 3anq:B, 3anq:C, 3anq:D, 3anr:A, 3anr:B, 3anr:C, 3anr:D, 4aze:B, 4aze:C, 8c3g:A, 8c3g:B, 8c3g:C, 8c3g:D, 8c3q:A, 8c3q:B, 8c3r:A, 8c3r:B, 6eif:A, 6eif:B, 6eif:D, 6eij:A, 6eij:B, 6eij:C, 6eij:D, 6eil:A, 6eil:B, 6eil:D, 6eip:A, 6eip:B, 6eip:C, 6eip:D, 6eiq:A, 6eiq:B, 6eiq:C, 6eiq:D, 6eir:A, 6eir:B, 6eir:C, 6eir:D, 6eis:A, 6eis:B, 6eis:C, 6eis:D, 6eiv:A, 6eiv:B, 6eiv:C, 6eiv:D, 6ej4:A, 6ej4:B, 6ej4:C, 6ej4:D, 7fhs:A, 7fhs:B, 7fhs:C, 7fhs:D, 7fht:A, 7fht:B, 7fht:C, 7fht:D, 6ln1:A, 6ln1:B, 4mq1:A, 4mq1:B, 4mq1:C, 4mq1:D, 4mq2:A, 4mq2:B, 4mq2:C, 4mq2:D, 4nct:A, 4nct:B, 4nct:C, 4nct:D, 7o7k:A, 7o7k:B, 7oy6:C, 6qu2:A, 6qu2:B, 6qu2:C, 6qu2:D, 8r8e:A, 8r8e:B, 8r8e:C, 8r8e:D, 6s11:A, 6s11:B, 6s14:A, 6s17:A, 6s1b:A, 6s1h:A, 6s1i:A, 6s1i:B, 6s1i:C, 6s1i:D, 6s1j:A, 8t2h:A, 8t2h:B, 6t6a:A, 6t6a:B, 6t6a:C, 6uip:A, 6uip:B, 6uwy:A, 6uwy:B, 6uwy:C, 6uwy:D, 2vx3:A, 2vx3:B, 2vx3:C, 2vx3:D, 2wo6:B, 2wo6:A, 6yf8:A, 6yf8:B, 6yf8:C, 6yf8:D, 4ylj:A, 4ylj:B, 4ylj:C, 4ylj:D, 4ylk:A, 4yll:A, 4yu2:A, 4yu2:B, 4yu2:C, 4yu2:D, 7z5n:A, 7z5n:B, 7z5n:C, 7z5n:D, 7z5n:E, 7z5n:F, 7z5n:G, 7zh8:A, 7zh8:B, 7zh8:C, 7zh8:D
43 8r2h:B 701 41 0.0238 0.0228 0.3902 0.17 8r2h:A
44 8r2h:B 701 108 0.0447 0.0428 0.2778 6.2 8r2h:A
45 8c2z:A 334 57 0.0328 0.0659 0.3860 0.19
46 7a9g:AAA 549 201 0.0715 0.0874 0.2388 0.19 7a9g:BBB, 7a9h:AAA, 7a9h:BBB, 8ogh:A, 8ogh:B
47 3dh7:A 318 69 0.0328 0.0692 0.3188 2.3 3dh7:B, 3dh7:C, 3dh7:D, 1vcf:A, 1vcf:B, 1vcg:A, 1vcg:B, 1vcg:C, 1vcg:D
48 4m9a:B 376 43 0.0209 0.0372 0.3256 5.2 4m9a:A
49 4zw2:A 319 60 0.0283 0.0596 0.3167 6.1
50 6jta:A 1298 41 0.0224 0.0116 0.3659 8.6 7dw7:A, 6jt7:A, 6jt8:A, 6jt9:A, 4l78:A, 4lgy:A, 6lyk:A, 6lyl:A, 6lym:A, 6lyo:A, 4mgh:A, 4r7g:A, 1t3t:A, 3ugj:A, 3ujn:A, 3umm:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218