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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
REVINFNTKWAFTKEATEVPKEMPEKWYWVTLPHSWNEIDGQDGGNDYYRGTCYYAKQLKKSELPEADCYYLELRGANAS
ADVYVNGKAVAHHDGGYSTWRVDITKELTEEENLIVIAVENGVNDRVYPQNADFTFYGGLYRDVNIIAVNKSHFDLDYYG
GPGIKVTPEIKGADASVEVEVFLTNAAADQKLVYTVKDAEGKEVAKTETAAGETKAVLSIPAVHLWNGKKDPYLYTAEVA
LVSGEEAVDAVSTRFGCRTFEIDPERGFILNGEEYPLRGVSRHQDRWGIGNALLPEHHREDIDLICELGATTIRLAHYQH
DQYFYDLCDERGLVIWAEIPYISSHMPNGRENTISQMKELVVQNYNHPSIVVWGLSNEITMEDLLENHRILNDMVHEMDH
TRLTTIAVVSMCDIHDPYIQIPDVISYNHYFGWYGGDVSMNGPWMDNFHKEFPNIPLGMSEYGCEALNWHTSDPKQGDYT
EEYQAYYHEEMIKQLFTRKYIWATHVWNMFDFGADARNEGGENGQNHKGLVTFDRKYKKDSFYAYKAWLSDEPFVHLCGK
RYVDRVEDTTKVTVYSNLPEVELFVNGKSAGKLQAEDHFFHFEVPNVGESTLVAVAGEYKDESHIRKVDTFNEEYSLK

The query sequence (length=638) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 8get:C 659 643 0.9984 0.9666 0.9907 0.0 8ges:A, 8ges:D, 8ges:C, 8ges:B, 8get:A, 8get:B, 8get:D, 6mvh:A, 6mvh:B, 6mvh:C
2 6mvg:A 637 637 0.7633 0.7645 0.7645 0.0 6mvg:B, 6mvg:C
3 7kgz:B 634 648 0.5423 0.5457 0.5340 0.0 7kgz:A
4 6mvf:A 643 647 0.4781 0.4743 0.4714 0.0 6mvf:B, 6mvf:C, 6mvf:D, 6mvf:E, 6mvf:F
5 5z1a:A 655 600 0.3636 0.3542 0.3867 4.48e-128
6 8dhl:B 853 670 0.3574 0.2673 0.3403 2.05e-101 8dhl:A
7 6d50:B 840 668 0.3433 0.2607 0.3278 2.87e-100 6d50:A, 6nzg:A, 6nzg:B, 5uj6:A, 5uj6:B
8 6mvh:D 305 259 0.2633 0.5508 0.6486 3.03e-98
9 6mvh:D 305 143 0.2053 0.4295 0.9161 1.43e-84
10 6ncz:C 589 538 0.2602 0.2818 0.3086 2.07e-59 6ncz:A, 6ncz:B, 6ncz:D, 6ncz:E, 6ncz:F
11 6d7j:A 799 640 0.2759 0.2203 0.2750 2.43e-58 6d7j:D
12 7vqm:A 584 536 0.2429 0.2654 0.2892 3.24e-50 7vqm:B, 7vqm:C, 7vqm:D
13 5t99:A 757 631 0.2649 0.2232 0.2678 1.08e-45 5t99:B
14 8e72:B 598 605 0.2633 0.2809 0.2777 2.13e-45 8dhw:A, 8dhw:B, 8e72:A
15 6cxs:B 599 612 0.2492 0.2654 0.2598 2.34e-44 6cxs:A
16 6d41:B 579 534 0.2351 0.2591 0.2809 2.92e-44 6d41:A, 6d6w:A, 6d6w:B, 6d6w:C, 6d6w:D, 6d7f:A, 6d7f:B, 6d7f:C, 6d7f:D, 6d7f:E, 6d7f:F
17 7cwd:A 803 663 0.2868 0.2279 0.2760 5.95e-41
18 5z1b:A 627 597 0.2398 0.2440 0.2563 2.30e-40 6ld0:A, 6ld0:B, 6ld0:C, 6ld0:D, 6ldb:A, 6ldb:B, 6ldb:C, 6ldb:D, 6ldc:A, 6ldc:B, 6ldc:C, 6ldc:D, 6ldd:A, 6ldd:B, 6ldd:C, 6ldd:D, 5z1b:B, 5z1b:C, 5z1b:D
19 6bjq:A 598 586 0.2320 0.2475 0.2526 4.46e-40 6d4o:A, 8gen:A, 8geo:A, 8geq:A, 8ger:A, 8ugt:A
20 4jkl:A 587 589 0.2288 0.2487 0.2479 1.30e-39 4jkl:B
21 6ncx:B 559 532 0.2273 0.2594 0.2726 2.10e-38 6ncx:D, 6ncx:A, 6ncx:C
22 6u7j:A 569 586 0.2257 0.2531 0.2457 2.33e-38 6u7j:C, 6u7j:D
23 6hpd:A 955 680 0.2649 0.1770 0.2485 1.12e-35
24 5c71:A 583 563 0.2210 0.2419 0.2504 2.56e-35 5c71:C
25 1bhg:A 611 612 0.2476 0.2586 0.2582 1.23e-34 1bhg:B, 3hn3:A, 3hn3:B, 3hn3:D, 3hn3:E
26 5t9g:C 811 724 0.2680 0.2109 0.2362 4.32e-34 5t9g:A, 5t9g:B, 5t9g:D
27 6jz4:A 576 514 0.2069 0.2292 0.2568 1.81e-33 6jz5:A, 6jz5:B, 6jz7:A, 6jz7:B, 6jz8:B
28 7kgy:A 593 518 0.2147 0.2310 0.2645 5.45e-33 7kgy:B, 7kgy:C, 7kgy:D
29 3lpf:A 603 616 0.2367 0.2504 0.2451 1.57e-32 5czk:A, 5czk:B, 4jhz:A, 4jhz:B, 3k4d:A, 3k4d:B, 6leg:A, 6leg:B, 6leg:C, 6leg:D, 6lej:A, 6lej:B, 6lel:A, 6lel:B, 6lem:A, 6lem:B, 3lpf:B, 3lpg:A, 3lpg:B, 8ohx:AAA, 8ohx:BBB, 7pr6:AAA, 7pr6:BBB
30 6ed2:A 591 510 0.2069 0.2234 0.2588 1.65e-32
31 5z19:B 601 534 0.2069 0.2196 0.2472 1.13e-30 6jz2:A, 6jz2:B, 6jz3:A, 6jz3:B, 6jz4:B, 6jz6:A, 6jz6:B, 6jz8:A, 5z19:A, 5z19:C, 5z19:D, 5z19:E, 5z19:F
32 5ldr:A 731 411 0.1787 0.1560 0.2774 1.50e-30 5ldr:B
33 4cu7:A 848 692 0.2712 0.2040 0.2500 6.29e-28 4cu8:A, 4cuc:A
34 6qud:A 837 433 0.1677 0.1278 0.2471 1.08e-25
35 7nit:D 1253 439 0.1661 0.0846 0.2415 9.41e-24 5dmy:A, 5dmy:B, 5dmy:C, 7nit:A, 7nit:B, 7nit:C, 7nit:E, 7nit:F, 6qub:A, 6qub:B, 6quc:A, 6quc:B
36 6bo6:A 493 331 0.1317 0.1704 0.2538 6.24e-22
37 6bo6:A 493 146 0.0627 0.0811 0.2740 1.55e-05
38 3ob8:A 1024 486 0.1740 0.1084 0.2284 5.25e-21 3ob8:B, 3ob8:D, 3ob8:C, 3oba:A, 3oba:C, 3oba:D, 3oba:B
39 6s6z:A 1083 329 0.1395 0.0822 0.2705 6.02e-21 6s6z:D, 6s6z:B, 6s6z:H, 6s6z:F, 6s6z:G, 6s6z:E, 6s6z:C, 6sd0:A, 6sd0:B, 6sd0:C, 6sd0:D
40 1yq2:A 1020 397 0.1614 0.1010 0.2594 5.02e-18 1yq2:B, 1yq2:C, 1yq2:D, 1yq2:E, 1yq2:F
41 3bga:A 1003 314 0.1395 0.0887 0.2834 9.52e-18 3bga:B
42 5n6u:A 811 364 0.1379 0.1085 0.2418 3.67e-17 5n6u:B, 5n6u:C, 5n6u:D
43 7xyr:A 546 401 0.1520 0.1777 0.2419 3.47e-15
44 6se9:A 989 329 0.1238 0.0799 0.2401 9.30e-14 6sea:A, 6seb:A, 6sec:A, 6sed:A, 6zjq:A, 6zjr:A, 6zjs:A, 6zjt:A, 6zju:A, 6zjw:A, 6zjx:A
45 2vzs:A 857 453 0.1614 0.1202 0.2274 2.24e-11 2vzs:B, 2vzt:A, 2vzt:B, 2vzu:A, 2vzu:B, 2vzv:A, 2vzv:B, 2x05:A, 2x05:B, 2x09:A, 2x09:B
46 7sf2:A 586 284 0.1097 0.1195 0.2465 2.24e-10 7sf2:B, 7sf2:C, 7sf2:D, 7sf2:E, 7sf2:F
47 7btk:C 1023 350 0.1270 0.0792 0.2314 6.92e-10 5a1a:A, 5a1a:B, 5a1a:C, 5a1a:D, 7brs:A, 7brs:B, 7brs:C, 7brs:D, 7btk:A, 7btk:B, 7btk:D, 6cvm:A, 6cvm:B, 6cvm:C, 6cvm:D, 3czj:A, 3czj:B, 3czj:C, 3czj:D, 1dp0:A, 1dp0:B, 1dp0:C, 1dp0:D, 4duv:A, 4duv:B, 4duv:C, 4duv:D, 4duw:A, 4duw:B, 4duw:C, 4duw:D, 4dux:A, 4dux:B, 4dux:C, 4dux:D, 3dym:A, 3dym:B, 3dym:C, 3dym:D, 3dyo:A, 3dyo:B, 3dyo:C, 3dyo:D, 3dyp:A, 3dyp:B, 3dyp:C, 3dyp:D, 3e1f:1, 3e1f:2, 3e1f:3, 3e1f:4, 1f4a:A, 1f4a:B, 1f4a:C, 1f4a:D, 1f4h:A, 1f4h:B, 1f4h:C, 1f4h:D, 1hn1:A, 1hn1:B, 1hn1:C, 1hn1:D, 3i3b:A, 3i3b:B, 3i3b:C, 3i3b:D, 3i3d:A, 3i3d:B, 3i3d:C, 3i3d:D, 3i3e:A, 3i3e:B, 3i3e:C, 3i3e:D, 3iap:A, 3iap:B, 3iap:C, 3iap:D, 3iaq:A, 3iaq:B, 3iaq:C, 3iaq:D, 3j7h:A, 3j7h:B, 3j7h:C, 3j7h:D, 1jyn:A, 1jyn:B, 1jyn:C, 1jyn:D, 1jyv:A, 1jyv:B, 1jyv:C, 1jyv:D, 1jyw:A, 1jyw:B, 1jyw:C, 1jyw:D, 1jyx:A, 1jyx:B, 1jyx:C, 1jyx:D, 1jz2:A, 1jz2:B, 1jz2:C, 1jz2:D, 1jz3:A, 1jz3:B, 1jz3:C, 1jz3:D, 1jz4:A, 1jz4:B, 1jz4:C, 1jz4:D, 1jz5:A, 1jz5:B, 1jz5:C, 1jz5:D, 1jz6:A, 1jz6:B, 1jz6:C, 1jz6:D, 1jz7:A, 1jz7:B, 1jz7:C, 1jz7:D, 1jz8:A, 1jz8:B, 1jz8:C, 1jz8:D, 6kuz:A, 6kuz:B, 6kuz:C, 6kuz:D, 3muy:1, 3muy:2, 3muy:3, 3muy:4, 3muz:1, 3muz:2, 3muz:3, 3muz:4, 3mv0:1, 3mv0:2, 3mv0:3, 3mv0:4, 3mv1:1, 3mv1:2, 3mv1:3, 3mv1:4, 1px3:A, 1px3:B, 1px3:C, 1px3:D, 1px4:A, 1px4:B, 1px4:C, 1px4:D, 3sep:A, 3sep:B, 3sep:C, 3sep:D, 3t08:A, 3t08:B, 3t08:C, 3t08:D, 3t09:A, 3t09:B, 3t09:C, 3t09:D, 3t0a:A, 3t0a:B, 3t0a:C, 3t0a:D, 3t0b:A, 3t0b:B, 3t0b:C, 3t0b:D, 3t0d:A, 3t0d:B, 3t0d:C, 3t0d:D, 3t2o:A, 3t2o:B, 3t2o:C, 3t2o:D, 3t2p:A, 3t2p:B, 3t2p:C, 3t2p:D, 3t2q:A, 3t2q:B, 3t2q:C, 3t2q:D, 6tsh:A, 6tsh:B, 6tsh:C, 6tsh:D, 6tsk:A, 6tsk:B, 6tsk:C, 6tsk:D, 4ttg:A, 4ttg:B, 4ttg:C, 4ttg:D, 6tte:A, 6tte:B, 6tte:C, 6tte:D, 4v40:A, 4v40:B, 4v40:C, 4v40:D, 4v40:E, 4v40:F, 4v40:G, 4v40:H, 4v40:I, 4v40:J, 4v40:K, 4v40:L, 4v40:M, 4v40:N, 4v40:O, 4v40:P, 4v41:A, 4v41:B, 4v41:C, 4v41:D, 4v41:E, 4v41:F, 4v41:G, 4v41:H, 4v41:I, 4v41:J, 4v41:K, 4v41:L, 4v41:M, 4v41:N, 4v41:O, 4v41:P, 4v44:A, 4v44:B, 4v44:C, 4v44:D, 4v44:E, 4v44:F, 4v44:G, 4v44:H, 4v44:I, 4v44:J, 4v44:K, 4v44:L, 4v44:M, 4v44:N, 4v44:O, 4v44:P, 4v45:A, 4v45:B, 4v45:C, 4v45:D, 4v45:E, 4v45:F, 4v45:G, 4v45:H, 4v45:I, 4v45:J, 4v45:K, 4v45:L, 4v45:M, 4v45:N, 4v45:O, 4v45:P, 3vd3:A, 3vd3:B, 3vd3:C, 3vd3:D, 3vd4:A, 3vd4:B, 3vd4:C, 3vd4:D, 3vd5:A, 3vd5:C, 3vd5:D, 3vd5:B, 3vd7:A, 3vd7:B, 3vd7:C, 3vd7:D, 3vd9:A, 3vd9:B, 3vd9:C, 3vd9:D, 3vda:A, 3vda:B, 3vda:C, 3vda:D, 3vdb:A, 3vdb:B, 3vdb:C, 3vdb:D, 3vdc:A, 3vdc:B, 3vdc:C, 3vdc:D, 8vt0:A, 8vt0:B, 8vt0:C, 8vt0:D, 6x1q:A, 6x1q:B, 6x1q:C, 6x1q:D
48 6bye:A 861 381 0.1285 0.0952 0.2152 5.03e-09 6bye:B, 6byg:A, 6byg:B, 6byi:A, 6byi:B
49 6ddt:A 862 273 0.1034 0.0766 0.2418 5.38e-05 6ddu:A
50 2vl4:B 841 447 0.1411 0.1070 0.2013 1.09e-04 7op6:A, 7op6:B, 7op7:A, 7op7:B, 2vjx:A, 2vjx:B, 2vl4:A, 2vmf:A, 2vmf:B, 2vo5:A, 2vo5:B, 2vot:A, 2vot:B, 2vqt:A, 2vqt:B, 2vqu:A, 2vqu:B, 2vr4:A, 2vr4:B, 2wbk:A, 2wbk:B
51 4uoj:A 917 66 0.0282 0.0196 0.2727 0.17 4cvu:A, 4uoj:B
52 4hi0:E 196 44 0.0251 0.0816 0.3636 2.5 4hi0:F
53 7qy5:B 320 46 0.0235 0.0469 0.3261 2.6 7qy5:D
54 7t1h:A 342 93 0.0376 0.0702 0.2581 2.9 7t1g:A, 7t1h:B, 7t1i:A, 6uj5:A
55 3gz8:C 156 20 0.0172 0.0705 0.5500 6.7 3gz8:A, 3gz8:B, 3gz8:D
56 4qpd:A 308 64 0.0282 0.0584 0.2812 7.6 4qpd:B, 4tt8:A, 4tts:A
57 3gz6:A 219 20 0.0172 0.0502 0.5500 8.2 3gz6:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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