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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
REQLFKKALEIKFTQEWGENKATEVSTDITSKKAKYLRLGTAQSPRKREFEQYGKEIAAKRGLPGYDPKLHLGGIPLGQR
QITPYVVSSTDTLCDGDDLHFVNNAAMQQMWDDIRRTVIVGMDLAHETLEKRLGKEVTPETINHYLEVLNHAMPGAAVVQ
EMMVETHPGLVDDCYVKVFTGDDELADEIDKRFLIDIDKQFGEEKAAQIKAAIGKTTWQAVHVPTIVVRTCDGATTSRWT
AMQIGMSFIAAYRMCAGEAAVADLAYAAKHAALVGMGDMLPARRARGPNEPGGLQFGYLADIVQADRVTDDKVKASLEVV
AAGAMLYDQIWLGSYMSGGVGFTQYATAAYTNNILDDFSYYGYEYAVDKYGGPAQAPATLETVKDIATETAIYAIEQYEY
FPTLLEDQFGGSQRAAVVAAAAGIATGLATGNSQAGLSGWYLAQYLLKEAEGRLGFFGYDLQDQCGAANVFSYQSDEGLP
LELRGPNYPNYAMNVGHQGEYAGIASSGHIGRGDAFVVNPLVKVAFADPLLNFDFTQVRKEFAKGAVREFDRCAGERALI
LPA

The query sequence (length=563) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 7nkg:D 565 563 1.0000 0.9965 1.0000 0.0 7nkg:A, 7nkg:G, 7nkg:J
2 1e6y:A 568 565 0.7389 0.7324 0.7363 0.0 1e6y:D, 8gf5:A, 8gf5:B
3 5a0y:A 548 563 0.6874 0.7062 0.6874 0.0 5a0y:D, 5a8k:A, 5a8k:D, 7b2h:A, 7b2h:D, 5g0r:A, 5g0r:D, 1hbm:A, 1hbm:D, 1hbn:A, 1hbn:D, 1hbo:A, 1hbo:D, 1hbu:A, 1hbu:D, 3m1v:A, 3m1v:D, 3m2r:A, 3m2r:D, 3m2u:A, 3m2u:D, 3m2v:A, 3m2v:D, 3m30:A, 3m30:D, 3m32:A, 3m32:D, 1mro:A, 1mro:D, 3pot:A, 3pot:D, 7suc:A, 7suc:a, 7sxm:A, 7sxm:D
4 5n1q:A 549 565 0.6412 0.6576 0.6389 0.0 5n1q:D, 5n28:A, 5n28:D, 5n2a:A
5 5a8w:D 549 529 0.6394 0.6557 0.6805 0.0 5a8r:A, 5a8r:D, 5a8r:G, 5a8r:J, 5a8w:A, 5a8w:G, 5a8w:J
6 1e6v:A 545 561 0.6465 0.6679 0.6488 0.0 1e6v:D
7 3sqg:A 578 570 0.4973 0.4844 0.4912 0.0 3sqg:D, 3sqg:G
8 7b1s:D 593 555 0.4263 0.4047 0.4324 2.85e-152 7b1s:A, 7b2c:A, 7b2c:D
9 2c43:A 280 40 0.0231 0.0464 0.3250 0.32 2cg5:A
10 2hu9:A 130 39 0.0231 0.1000 0.3333 3.5 2hu9:B
11 3kfu:C 377 57 0.0337 0.0504 0.3333 4.7 3kfu:A, 3kfu:D, 3kfu:B
12 5v13:A 268 60 0.0373 0.0784 0.3500 8.4 5v13:B, 5v13:C
13 7vwp:B 491 66 0.0355 0.0407 0.3030 9.6 7vwp:D, 7vwp:A, 7vwp:C
14 7vax:F 471 138 0.0622 0.0743 0.2536 10.0 3a5c:E, 8gxw:E, 8gxx:E, 6r0w:E, 6r0y:D, 6r10:F, 7val:E, 7van:E, 7vap:E, 7vaq:E, 7var:E, 7vas:E, 7vat:E, 7vav:E, 7vaw:E, 7vay:E, 7vb0:E, 3w3a:E, 3w3a:M

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218