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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
REIFNLNEKWAFSKEAIKPPVAMPQNWYWVNLPHTWNAIDGQDGGNDYYRGTCFYAKEVQKEELPEGEQYYLEFLGVNAS
ADVYVNGNHLDHHDGGYSTWRVNMTDALTDGKNLIVVAVDNSANDRVYPQKADFTFYGGMYRDVNIIAVNKSHFDLDYYG
GNGLKVTPEVADKNAKIAVEVFLSGEKAGQQLVYQITDAEGVLAAETKTGISDKQVNLEITDVHLWNGRKDPYLYTATVR
LMEDGVCIDSVSTRFGCRTFTIDPDKGFFLNGNSYPLRGVSRHQDRAGNGNALLPEHHREDIDLICEMGATTIRLAHYQH
AQYFYDLCDEKGLVLWAEIPYISQHMKNGRENTISQMKELIVQNYNHPSIVVWGLSNEITMSGEDLMENHHILNDLAHEM
DPTRLTTMAVVSMCDMHNPYIQIPDVVSYNHYFGWYGGDTSMNGPWMDEFHKEFPKIPIGMSEYGCEALNWHTSDPKQGD
YTEEYQAHYHEELIKQLYTRPYIWATHVWNMFDFAADARNEGGENGMNHKGLVTFDRKYKKDAFYAYKAWLSDEPFVHIC
GKRYVDRVENVTKVTVYSNQKTVELFANGESLGKKEASDHFFYFEVPNHGETKLLAVAGECRDESFIKKVEKFNEAY

The query sequence (length=637) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 6mvg:A 637 637 1.0000 1.0000 1.0000 0.0 6mvg:B, 6mvg:C
2 8get:C 659 640 0.7661 0.7405 0.7625 0.0 8ges:A, 8ges:D, 8ges:C, 8ges:B, 8get:A, 8get:B, 8get:D, 6mvh:A, 6mvh:B, 6mvh:C
3 7kgz:B 634 651 0.5573 0.5599 0.5453 0.0 7kgz:A
4 6mvf:A 643 644 0.4662 0.4619 0.4612 0.0 6mvf:B, 6mvf:C, 6mvf:D, 6mvf:E, 6mvf:F
5 5z1a:A 655 595 0.3878 0.3771 0.4151 1.14e-140
6 8dhl:B 853 666 0.3689 0.2755 0.3529 3.63e-108 8dhl:A
7 6d50:B 840 665 0.3532 0.2679 0.3383 4.52e-101 6d50:A, 6nzg:A, 6nzg:B, 5uj6:A, 5uj6:B
8 6mvh:D 305 261 0.2339 0.4885 0.5709 1.07e-82
9 6mvh:D 305 142 0.1570 0.3279 0.7042 1.28e-63
10 6d7j:A 799 645 0.2826 0.2253 0.2791 7.11e-59 6d7j:D
11 6ncz:C 589 541 0.2512 0.2716 0.2957 1.80e-55 6ncz:A, 6ncz:B, 6ncz:D, 6ncz:E, 6ncz:F
12 6cxs:B 599 601 0.2449 0.2604 0.2596 5.40e-48 6cxs:A
13 5z1b:A 627 553 0.2402 0.2440 0.2767 3.82e-47 6ld0:A, 6ld0:B, 6ld0:C, 6ld0:D, 6ldb:A, 6ldb:B, 6ldb:C, 6ldb:D, 6ldc:A, 6ldc:B, 6ldc:C, 6ldc:D, 6ldd:A, 6ldd:B, 6ldd:C, 6ldd:D, 5z1b:B, 5z1b:C, 5z1b:D
14 8e72:B 598 596 0.2622 0.2793 0.2802 1.20e-46 8dhw:A, 8dhw:B, 8e72:A
15 6d41:B 579 532 0.2418 0.2660 0.2895 1.34e-46 6d41:A, 6d6w:A, 6d6w:B, 6d6w:C, 6d6w:D, 6d7f:A, 6d7f:B, 6d7f:C, 6d7f:D, 6d7f:E, 6d7f:F
16 7vqm:A 584 535 0.2433 0.2654 0.2897 1.90e-45 7vqm:B, 7vqm:C, 7vqm:D
17 4jkl:A 587 597 0.2323 0.2521 0.2479 8.55e-45 4jkl:B
18 6bjq:A 598 584 0.2386 0.2542 0.2603 2.42e-44 6d4o:A, 8gen:A, 8geo:A, 8geq:A, 8ger:A, 8ugt:A
19 5t99:A 757 632 0.2637 0.2219 0.2658 6.73e-44 5t99:B
20 6u7j:A 569 586 0.2245 0.2513 0.2440 1.53e-40 6u7j:C, 6u7j:D
21 5ldr:A 731 574 0.2527 0.2202 0.2805 2.72e-39 5ldr:B
22 3lpf:A 603 611 0.2543 0.2687 0.2651 3.36e-39 5czk:A, 5czk:B, 4jhz:A, 4jhz:B, 3k4d:A, 3k4d:B, 6leg:A, 6leg:B, 6leg:C, 6leg:D, 6lej:A, 6lej:B, 6lel:A, 6lel:B, 6lem:A, 6lem:B, 3lpf:B, 3lpg:A, 3lpg:B, 8ohx:AAA, 8ohx:BBB, 7pr6:AAA, 7pr6:BBB
23 7kgy:A 593 601 0.2465 0.2648 0.2612 6.30e-39 7kgy:B, 7kgy:C, 7kgy:D
24 5t9g:C 811 698 0.2669 0.2096 0.2436 1.17e-38 5t9g:A, 5t9g:B, 5t9g:D
25 6hpd:A 955 692 0.2904 0.1937 0.2673 3.42e-38
26 6ncx:B 559 510 0.2151 0.2451 0.2686 6.39e-38 6ncx:D, 6ncx:A, 6ncx:C
27 6ed2:A 591 518 0.2151 0.2318 0.2645 3.51e-36
28 7cwd:A 803 656 0.2716 0.2154 0.2637 5.74e-36
29 5c71:A 583 600 0.2276 0.2487 0.2417 1.56e-35 5c71:C
30 6jz4:A 576 569 0.2182 0.2413 0.2443 2.77e-34 6jz5:A, 6jz5:B, 6jz7:A, 6jz7:B, 6jz8:B
31 5z19:B 601 590 0.2214 0.2346 0.2390 2.77e-32 6jz2:A, 6jz2:B, 6jz3:A, 6jz3:B, 6jz4:B, 6jz6:A, 6jz6:B, 6jz8:A, 5z19:A, 5z19:C, 5z19:D, 5z19:E, 5z19:F
32 1bhg:A 611 586 0.2292 0.2390 0.2491 5.18e-32 1bhg:B, 3hn3:A, 3hn3:B, 3hn3:D, 3hn3:E
33 4cu7:A 848 709 0.2763 0.2075 0.2482 3.79e-31 4cu8:A, 4cuc:A
34 6qud:A 837 423 0.1743 0.1326 0.2624 4.46e-27
35 6bo6:A 493 326 0.1381 0.1785 0.2699 5.63e-27
36 6bo6:A 493 156 0.0644 0.0832 0.2628 2.40e-04
37 7nit:D 1253 427 0.1743 0.0886 0.2600 6.40e-27 5dmy:A, 5dmy:B, 5dmy:C, 7nit:A, 7nit:B, 7nit:C, 7nit:E, 7nit:F, 6qub:A, 6qub:B, 6quc:A, 6quc:B
38 6s6z:A 1083 337 0.1491 0.0877 0.2819 6.95e-25 6s6z:D, 6s6z:B, 6s6z:H, 6s6z:F, 6s6z:G, 6s6z:E, 6s6z:C, 6sd0:A, 6sd0:B, 6sd0:C, 6sd0:D
39 5n6u:A 811 453 0.1680 0.1319 0.2362 2.23e-19 5n6u:B, 5n6u:C, 5n6u:D
40 1yq2:A 1020 329 0.1397 0.0873 0.2705 2.40e-19 1yq2:B, 1yq2:C, 1yq2:D, 1yq2:E, 1yq2:F
41 3ob8:A 1024 494 0.1774 0.1104 0.2287 3.83e-19 3ob8:B, 3ob8:D, 3ob8:C, 3oba:A, 3oba:C, 3oba:D, 3oba:B
42 3bga:A 1003 335 0.1350 0.0857 0.2567 2.07e-17 3bga:B
43 7xyr:A 546 375 0.1460 0.1703 0.2480 2.43e-14
44 7btk:C 1023 404 0.1570 0.0978 0.2475 5.47e-14 5a1a:A, 5a1a:B, 5a1a:C, 5a1a:D, 7brs:A, 7brs:B, 7brs:C, 7brs:D, 7btk:A, 7btk:B, 7btk:D, 6cvm:A, 6cvm:B, 6cvm:C, 6cvm:D, 3czj:A, 3czj:B, 3czj:C, 3czj:D, 1dp0:A, 1dp0:B, 1dp0:C, 1dp0:D, 4duv:A, 4duv:B, 4duv:C, 4duv:D, 4duw:A, 4duw:B, 4duw:C, 4duw:D, 4dux:A, 4dux:B, 4dux:C, 4dux:D, 3dym:A, 3dym:B, 3dym:C, 3dym:D, 3dyo:A, 3dyo:B, 3dyo:C, 3dyo:D, 3dyp:A, 3dyp:B, 3dyp:C, 3dyp:D, 3e1f:1, 3e1f:2, 3e1f:3, 3e1f:4, 1f4a:A, 1f4a:B, 1f4a:C, 1f4a:D, 1f4h:A, 1f4h:B, 1f4h:C, 1f4h:D, 1hn1:A, 1hn1:B, 1hn1:C, 1hn1:D, 3i3b:A, 3i3b:B, 3i3b:C, 3i3b:D, 3i3d:A, 3i3d:B, 3i3d:C, 3i3d:D, 3i3e:A, 3i3e:B, 3i3e:C, 3i3e:D, 3iap:A, 3iap:B, 3iap:C, 3iap:D, 3iaq:A, 3iaq:B, 3iaq:C, 3iaq:D, 3j7h:A, 3j7h:B, 3j7h:C, 3j7h:D, 1jyn:A, 1jyn:B, 1jyn:C, 1jyn:D, 1jyv:A, 1jyv:B, 1jyv:C, 1jyv:D, 1jyw:A, 1jyw:B, 1jyw:C, 1jyw:D, 1jyx:A, 1jyx:B, 1jyx:C, 1jyx:D, 1jz2:A, 1jz2:B, 1jz2:C, 1jz2:D, 1jz3:A, 1jz3:B, 1jz3:C, 1jz3:D, 1jz4:A, 1jz4:B, 1jz4:C, 1jz4:D, 1jz5:A, 1jz5:B, 1jz5:C, 1jz5:D, 1jz6:A, 1jz6:B, 1jz6:C, 1jz6:D, 1jz7:A, 1jz7:B, 1jz7:C, 1jz7:D, 1jz8:A, 1jz8:B, 1jz8:C, 1jz8:D, 6kuz:A, 6kuz:B, 6kuz:C, 6kuz:D, 3muy:1, 3muy:2, 3muy:3, 3muy:4, 3muz:1, 3muz:2, 3muz:3, 3muz:4, 3mv0:1, 3mv0:2, 3mv0:3, 3mv0:4, 3mv1:1, 3mv1:2, 3mv1:3, 3mv1:4, 1px3:A, 1px3:B, 1px3:C, 1px3:D, 1px4:A, 1px4:B, 1px4:C, 1px4:D, 3sep:A, 3sep:B, 3sep:C, 3sep:D, 3t08:A, 3t08:B, 3t08:C, 3t08:D, 3t09:A, 3t09:B, 3t09:C, 3t09:D, 3t0a:A, 3t0a:B, 3t0a:C, 3t0a:D, 3t0b:A, 3t0b:B, 3t0b:C, 3t0b:D, 3t0d:A, 3t0d:B, 3t0d:C, 3t0d:D, 3t2o:A, 3t2o:B, 3t2o:C, 3t2o:D, 3t2p:A, 3t2p:B, 3t2p:C, 3t2p:D, 3t2q:A, 3t2q:B, 3t2q:C, 3t2q:D, 6tsh:A, 6tsh:B, 6tsh:C, 6tsh:D, 6tsk:A, 6tsk:B, 6tsk:C, 6tsk:D, 4ttg:A, 4ttg:B, 4ttg:C, 4ttg:D, 6tte:A, 6tte:B, 6tte:C, 6tte:D, 4v40:A, 4v40:B, 4v40:C, 4v40:D, 4v40:E, 4v40:F, 4v40:G, 4v40:H, 4v40:I, 4v40:J, 4v40:K, 4v40:L, 4v40:M, 4v40:N, 4v40:O, 4v40:P, 4v41:A, 4v41:B, 4v41:C, 4v41:D, 4v41:E, 4v41:F, 4v41:G, 4v41:H, 4v41:I, 4v41:J, 4v41:K, 4v41:L, 4v41:M, 4v41:N, 4v41:O, 4v41:P, 4v44:A, 4v44:B, 4v44:C, 4v44:D, 4v44:E, 4v44:F, 4v44:G, 4v44:H, 4v44:I, 4v44:J, 4v44:K, 4v44:L, 4v44:M, 4v44:N, 4v44:O, 4v44:P, 4v45:A, 4v45:B, 4v45:C, 4v45:D, 4v45:E, 4v45:F, 4v45:G, 4v45:H, 4v45:I, 4v45:J, 4v45:K, 4v45:L, 4v45:M, 4v45:N, 4v45:O, 4v45:P, 3vd3:A, 3vd3:B, 3vd3:C, 3vd3:D, 3vd4:A, 3vd4:B, 3vd4:C, 3vd4:D, 3vd5:A, 3vd5:C, 3vd5:D, 3vd5:B, 3vd7:A, 3vd7:B, 3vd7:C, 3vd7:D, 3vd9:A, 3vd9:B, 3vd9:C, 3vd9:D, 3vda:A, 3vda:B, 3vda:C, 3vda:D, 3vdb:A, 3vdb:B, 3vdb:C, 3vdb:D, 3vdc:A, 3vdc:B, 3vdc:C, 3vdc:D, 8vt0:A, 8vt0:B, 8vt0:C, 8vt0:D, 6x1q:A, 6x1q:B, 6x1q:C, 6x1q:D
45 6se9:A 989 355 0.1256 0.0809 0.2254 1.40e-12 6sea:A, 6seb:A, 6sec:A, 6sed:A, 6zjq:A, 6zjr:A, 6zjs:A, 6zjt:A, 6zju:A, 6zjw:A, 6zjx:A
46 6bye:A 861 389 0.1413 0.1045 0.2314 5.66e-12 6bye:B, 6byg:A, 6byg:B, 6byi:A, 6byi:B
47 7sf2:A 586 403 0.1366 0.1485 0.2159 1.37e-10 7sf2:B, 7sf2:C, 7sf2:D, 7sf2:E, 7sf2:F
48 2vl4:B 841 476 0.1680 0.1272 0.2248 1.50e-07 7op6:A, 7op6:B, 7op7:A, 7op7:B, 2vjx:A, 2vjx:B, 2vl4:A, 2vmf:A, 2vmf:B, 2vo5:A, 2vo5:B, 2vot:A, 2vot:B, 2vqt:A, 2vqt:B, 2vqu:A, 2vqu:B, 2vr4:A, 2vr4:B, 2wbk:A, 2wbk:B
49 2vzs:A 857 291 0.1036 0.0770 0.2268 7.68e-06 2vzs:B, 2vzt:A, 2vzt:B, 2vzu:A, 2vzu:B, 2vzv:A, 2vzv:B, 2x05:A, 2x05:B, 2x09:A, 2x09:B
50 6ddt:A 862 276 0.1020 0.0754 0.2355 0.013 6ddu:A
51 8sr6:A 451 63 0.0361 0.0510 0.3651 0.68 5czy:A, 8swi:A
52 6lxn:A 110 48 0.0204 0.1182 0.2708 3.1 6lxn:B
53 8cnr:A 548 108 0.0471 0.0547 0.2778 3.1 8cns:A
54 6w98:A 1312 52 0.0267 0.0130 0.3269 3.1 6wbx:A
55 4uoj:A 917 68 0.0267 0.0185 0.2500 3.2 4cvu:A, 4uoj:B
56 6wby:A 1250 52 0.0267 0.0136 0.3269 3.3
57 4v2x:A 534 309 0.1115 0.1330 0.2298 3.9
58 2whl:A 294 70 0.0298 0.0646 0.2714 4.2
59 3gz8:C 156 20 0.0173 0.0705 0.5500 4.8 3gz8:A, 3gz8:B, 3gz8:D
60 3gz6:A 219 44 0.0235 0.0685 0.3409 5.6 3gz6:B
61 4hi0:E 196 44 0.0235 0.0765 0.3409 6.2 4hi0:F
62 6xn8:A 540 56 0.0298 0.0352 0.3393 7.6 6xn8:B
63 1e6y:F 247 40 0.0251 0.0648 0.4000 8.8 1e6y:C, 8gf5:E

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218