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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
RCDLELETNGRDHHTADLCREKLVVRRGQPFWLTLHFRNYELTFSVVTGPAPSQEAGTKARFPLRDAVEDWTATVVDQQD
CTLSLQLTTPANAPIGLYRLSLVLGHFILLFNAWCPADAVYLDSEEERQEYVLTQQGFIYQGSAKFIKNIPWNFGQFEDG
ILDICLILLDVNPKFLKNAGRDCSRRSSPVYVGRVVSGMVNCNDDQGVLLGRWDNNYGDGVSPMSWIGSVDILRRWKNHG
CQRVKYGQCWVFAAVACTVLRCLGIPTRVVTNYNSAHDQNSNLLIEYFRNEFGEIQGDEMIWNFHCWVESWMTRPDLQPG
YEGWQALDPTPQTYCCGPVPVRAIKEGDLSTKYDAPFVFAEVNADVVDWIQQDDGSVHKSINRSLIVGLKISTKSVGRDE
REDITHTYKYPEGSSEEREAFTRANHLNKLAETGMAMRIRVGQSMNMGSDFDVFAHITNNTAEEYVCRLLLCARTVSYNG
ILGPECGTKYLLNLNLEPFSEKSVPLCILYEKYRDCLTESNLIKVRALLVEPVINSYLLAERDLYLENPEIKIRILGEPK
QKRKLVAEVSLQNPLPVALEGCTFTVEGAGLTEEQKTVEIPDPVEAGEEVKVRMDLLPLHMGLHKLVVNFESDKLKAVKG
FRNVIIGPA

The query sequence (length=649) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 6kzb:C 649 649 1.0000 1.0000 1.0000 0.0
2 4pyg:A 685 679 1.0000 0.9474 0.9558 0.0 6a8p:A, 6a8p:B, 6a8p:C, 9bc3:A, 9bc3:B, 9bc4:A, 1kv3:A, 1kv3:B, 1kv3:C, 1kv3:D, 1kv3:E, 1kv3:F, 6kzb:A, 6kzb:B, 3ly6:A, 3ly6:B, 3ly6:C, 4pyg:B, 4pyg:E, 8tr9:A
3 2q3z:A 655 670 0.9492 0.9405 0.9194 0.0 9bc2:A, 3s3j:A
4 3s3s:A 620 665 0.9106 0.9532 0.8887 0.0 3s3p:A
5 1g0d:A 666 676 0.4499 0.4384 0.4320 2.05e-180
6 1l9m:B 681 668 0.3960 0.3774 0.3847 9.62e-159 1l9m:A, 1l9n:A, 1l9n:B, 1nud:A, 1nud:B, 1nuf:A, 1nug:A, 1nug:B, 8oxv:A, 8oxw:A, 8oxx:A
7 1ex0:B 716 683 0.3929 0.3561 0.3734 9.89e-127 1ex0:A, 1ggy:A, 1ggy:B, 4kty:A, 4kty:B, 5mhl:A, 5mhl:B, 5mhn:A, 1qrk:A, 1qrk:B
8 5mhn:B 685 673 0.3867 0.3664 0.3730 5.44e-124 5mhm:A, 5mhm:B, 5mho:A, 5mho:B
9 2v6k:A 214 70 0.0324 0.0981 0.3000 2.9 2jl4:A, 2jl4:B, 2v6k:B
10 2gf0:B 174 50 0.0277 0.1034 0.3600 7.3 2gf0:A, 2gf0:C, 2gf0:D

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218