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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
RALSCQTLAAGYYHVCPDGLMDDGRGGCVVEKECPCVHNNDLYSSGAKIKVDCNTCTCKRGRWVCTQAVCHGTCSIYGSG
HYITFDGKYYDFDGHCSYVAVQDYCGLGSFSIITENVPCGTTGVTCSKAIKIFMGRTELKLEDKHRVVIQRDEGHHVAYT
TREVGQYLVVESSTGIIVIWDKRTTVFIKLAPSYKGTVCGLCGNFDHRSNNDFTTRDHMVVSSELDFGNSWKEAPTCPDV
STNPEPCSLNPHRRSWAEKQCSILKSSVFSICHSKVDPKPFYEACVHDSCSCDTGGDCECFCSAVASYAQECTKEGACVF
WRTPDLCPIFCDYYNPPHECEWHYEPCGNRSFETCRTINGIHSNISVSYLEGCYPRCPKDRPIYEEDLKKCVTADKCGCY
VEDTHYPCCLWSDWINEDHPSSGSDDGDRETFDGVCGAPEDIECRSVKDPHLSLEQHGQKVQCDVSVGFICKNEDQFGNG
PFGLCYDYKIRVNCCWP

The query sequence (length=497) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 7a5o:A 1205 497 1.0000 0.4124 1.0000 0.0 7a5o:B, 7a5o:C, 7a5o:D, 7a5o:E, 7a5o:F, 7a5o:G, 7a5o:H, 7a5o:I, 7a5o:J, 8ck2:A, 7pov:A, 7pov:B, 7pov:C, 7pov:D, 7pp6:A, 7pp6:B, 7pp6:C, 7pp6:D, 7pp6:E, 7pp6:G, 7prl:A, 6rbf:A, 6rbf:B, 6rbf:C, 6rbf:D, 6tm2:A, 6tm2:B, 6tm2:C, 6tm2:D, 6tm2:E, 6tm2:F, 6tm6:A
2 7a5o:A 1205 414 0.2656 0.1095 0.3188 1.10e-47 7a5o:B, 7a5o:C, 7a5o:D, 7a5o:E, 7a5o:F, 7a5o:G, 7a5o:H, 7a5o:I, 7a5o:J, 8ck2:A, 7pov:A, 7pov:B, 7pov:C, 7pov:D, 7pp6:A, 7pp6:B, 7pp6:C, 7pp6:D, 7pp6:E, 7pp6:G, 7prl:A, 6rbf:A, 6rbf:B, 6rbf:C, 6rbf:D, 6tm2:A, 6tm2:B, 6tm2:C, 6tm2:D, 6tm2:E, 6tm2:F, 6tm6:A
3 7a5o:A 1205 344 0.1831 0.0755 0.2645 2.11e-20 7a5o:B, 7a5o:C, 7a5o:D, 7a5o:E, 7a5o:F, 7a5o:G, 7a5o:H, 7a5o:I, 7a5o:J, 8ck2:A, 7pov:A, 7pov:B, 7pov:C, 7pov:D, 7pp6:A, 7pp6:B, 7pp6:C, 7pp6:D, 7pp6:E, 7pp6:G, 7prl:A, 6rbf:A, 6rbf:B, 6rbf:C, 6rbf:D, 6tm2:A, 6tm2:B, 6tm2:C, 6tm2:D, 6tm2:E, 6tm2:F, 6tm6:A
4 8oes:A 1168 414 0.4447 0.1892 0.5338 4.29e-150 8oer:A, 8oer:B, 8oer:C, 8oer:D, 8oes:B, 8oes:C, 8oes:D, 8oes:E, 8oes:F, 8oes:G, 8oes:H
5 8oes:A 1168 445 0.2817 0.1199 0.3146 4.30e-50 8oer:A, 8oer:B, 8oer:C, 8oer:D, 8oes:B, 8oes:C, 8oes:D, 8oes:E, 8oes:F, 8oes:G, 8oes:H
6 8oes:A 1168 339 0.1751 0.0745 0.2566 1.46e-20 8oer:A, 8oer:B, 8oer:C, 8oer:D, 8oes:B, 8oes:C, 8oes:D, 8oes:E, 8oes:F, 8oes:G, 8oes:H
7 7pmv:B 1141 405 0.3018 0.1315 0.3704 1.14e-82 7kwo:V, 6n29:A, 6n29:B, 7pmv:A, 7pmv:D, 7pmv:E, 7pnf:B, 7pnf:D, 7wn3:F, 7wn3:H, 7wn3:C, 7wn3:D, 7wn4:F, 7wn4:H, 7wn6:F, 7wn6:H, 7wn6:C, 7wn6:D, 7wpp:F, 7wpp:H, 7wpq:C, 7wpq:D, 7wpq:F, 7wpq:H, 7wpr:a, 7wpr:b, 7wpr:C, 7wpr:c, 7wpr:D, 7wpr:d, 7wpr:e, 7wpr:f, 7wpr:S, 7wpr:T, 7wpr:U, 7wpr:V, 7wpr:W, 7wpr:X, 7wpr:Y, 7wpr:Z, 7wps:Z, 7wps:b, 7wps:C, 7wps:D, 7wps:F, 7wps:H, 7wps:J, 7wps:L, 7wps:N, 7wps:P, 7wps:R, 7wps:T, 7wps:V, 7wps:X, 7wqt:a, 7wqt:b, 7wqt:C, 7wqt:c, 7wqt:D, 7wqt:d, 7wqt:e, 7wqt:f, 7wqt:S, 7wqt:T, 7wqt:U, 7wqt:V, 7wqt:W, 7wqt:X, 7wqt:Y, 7wqt:Z, 7zwh:D, 7zwh:E
8 7pmv:B 1141 402 0.2696 0.1174 0.3333 2.62e-58 7kwo:V, 6n29:A, 6n29:B, 7pmv:A, 7pmv:D, 7pmv:E, 7pnf:B, 7pnf:D, 7wn3:F, 7wn3:H, 7wn3:C, 7wn3:D, 7wn4:F, 7wn4:H, 7wn6:F, 7wn6:H, 7wn6:C, 7wn6:D, 7wpp:F, 7wpp:H, 7wpq:C, 7wpq:D, 7wpq:F, 7wpq:H, 7wpr:a, 7wpr:b, 7wpr:C, 7wpr:c, 7wpr:D, 7wpr:d, 7wpr:e, 7wpr:f, 7wpr:S, 7wpr:T, 7wpr:U, 7wpr:V, 7wpr:W, 7wpr:X, 7wpr:Y, 7wpr:Z, 7wps:Z, 7wps:b, 7wps:C, 7wps:D, 7wps:F, 7wps:H, 7wps:J, 7wps:L, 7wps:N, 7wps:P, 7wps:R, 7wps:T, 7wps:V, 7wps:X, 7wqt:a, 7wqt:b, 7wqt:C, 7wqt:c, 7wqt:D, 7wqt:d, 7wqt:e, 7wqt:f, 7wqt:S, 7wqt:T, 7wqt:U, 7wqt:V, 7wqt:W, 7wqt:X, 7wqt:Y, 7wqt:Z, 7zwh:D, 7zwh:E
9 7pmv:B 1141 395 0.2334 0.1017 0.2937 1.59e-28 7kwo:V, 6n29:A, 6n29:B, 7pmv:A, 7pmv:D, 7pmv:E, 7pnf:B, 7pnf:D, 7wn3:F, 7wn3:H, 7wn3:C, 7wn3:D, 7wn4:F, 7wn4:H, 7wn6:F, 7wn6:H, 7wn6:C, 7wn6:D, 7wpp:F, 7wpp:H, 7wpq:C, 7wpq:D, 7wpq:F, 7wpq:H, 7wpr:a, 7wpr:b, 7wpr:C, 7wpr:c, 7wpr:D, 7wpr:d, 7wpr:e, 7wpr:f, 7wpr:S, 7wpr:T, 7wpr:U, 7wpr:V, 7wpr:W, 7wpr:X, 7wpr:Y, 7wpr:Z, 7wps:Z, 7wps:b, 7wps:C, 7wps:D, 7wps:F, 7wps:H, 7wps:J, 7wps:L, 7wps:N, 7wps:P, 7wps:R, 7wps:T, 7wps:V, 7wps:X, 7wqt:a, 7wqt:b, 7wqt:C, 7wqt:c, 7wqt:D, 7wqt:d, 7wqt:e, 7wqt:f, 7wqt:S, 7wqt:T, 7wqt:U, 7wqt:V, 7wqt:W, 7wqt:X, 7wqt:Y, 7wqt:Z, 7zwh:D, 7zwh:E
10 7pmv:B 1141 52 0.0342 0.0149 0.3269 0.28 7kwo:V, 6n29:A, 6n29:B, 7pmv:A, 7pmv:D, 7pmv:E, 7pnf:B, 7pnf:D, 7wn3:F, 7wn3:H, 7wn3:C, 7wn3:D, 7wn4:F, 7wn4:H, 7wn6:F, 7wn6:H, 7wn6:C, 7wn6:D, 7wpp:F, 7wpp:H, 7wpq:C, 7wpq:D, 7wpq:F, 7wpq:H, 7wpr:a, 7wpr:b, 7wpr:C, 7wpr:c, 7wpr:D, 7wpr:d, 7wpr:e, 7wpr:f, 7wpr:S, 7wpr:T, 7wpr:U, 7wpr:V, 7wpr:W, 7wpr:X, 7wpr:Y, 7wpr:Z, 7wps:Z, 7wps:b, 7wps:C, 7wps:D, 7wps:F, 7wps:H, 7wps:J, 7wps:L, 7wps:N, 7wps:P, 7wps:R, 7wps:T, 7wps:V, 7wps:X, 7wqt:a, 7wqt:b, 7wqt:C, 7wqt:c, 7wqt:D, 7wqt:d, 7wqt:e, 7wqt:f, 7wqt:S, 7wqt:T, 7wqt:U, 7wqt:V, 7wqt:W, 7wqt:X, 7wqt:Y, 7wqt:Z, 7zwh:D, 7zwh:E
11 8d3d:A 1314 393 0.2978 0.1126 0.3766 8.24e-82 8d3c:A, 8d3c:B, 8d3c:C, 8d3c:D, 8d3c:E, 8d3c:F, 8d3c:G, 8d3c:H, 8d3c:I, 8d3c:J, 8d3c:K, 8d3c:L, 8d3c:M, 8d3c:N, 8d3c:O, 8d3c:P, 8d3d:B, 8d3d:C, 8d3d:D, 8d3d:E, 8d3d:F, 8d3d:G, 8d3d:H, 8d3d:I, 8d3d:J, 8d3d:K, 8d3d:L, 8d3d:M, 8d3d:N, 8d3d:O, 8d3d:P, 7f49:A, 3hxo:A, 3hxq:A, 7wn3:A, 7wn3:B, 7wn3:E, 7wn3:G, 7wn4:E, 7wn4:G, 7wn6:A, 7wn6:B, 7wn6:E, 7wn6:G, 7wpp:E, 7wpp:G, 7wpq:A, 7wpq:B, 7wpq:E, 7wpq:G, 7wpr:A, 7wpr:B, 7wpr:E, 7wpr:F, 7wpr:G, 7wpr:H, 7wpr:I, 7wpr:J, 7wpr:K, 7wpr:L, 7wpr:M, 7wpr:N, 7wpr:O, 7wpr:P, 7wpr:Q, 7wpr:R, 7wps:A, 7wps:B, 7wps:E, 7wps:G, 7wps:I, 7wps:K, 7wps:M, 7wps:O, 7wps:Q, 7wps:S, 7wps:U, 7wps:W, 7wps:Y, 7wps:a, 7wqt:A, 7wqt:B, 7wqt:E, 7wqt:F, 7wqt:G, 7wqt:H, 7wqt:I, 7wqt:J, 7wqt:K, 7wqt:L, 7wqt:M, 7wqt:N, 7wqt:O, 7wqt:P, 7wqt:Q, 7wqt:R
12 8d3d:A 1314 402 0.2696 0.1020 0.3333 3.48e-58 8d3c:A, 8d3c:B, 8d3c:C, 8d3c:D, 8d3c:E, 8d3c:F, 8d3c:G, 8d3c:H, 8d3c:I, 8d3c:J, 8d3c:K, 8d3c:L, 8d3c:M, 8d3c:N, 8d3c:O, 8d3c:P, 8d3d:B, 8d3d:C, 8d3d:D, 8d3d:E, 8d3d:F, 8d3d:G, 8d3d:H, 8d3d:I, 8d3d:J, 8d3d:K, 8d3d:L, 8d3d:M, 8d3d:N, 8d3d:O, 8d3d:P, 7f49:A, 3hxo:A, 3hxq:A, 7wn3:A, 7wn3:B, 7wn3:E, 7wn3:G, 7wn4:E, 7wn4:G, 7wn6:A, 7wn6:B, 7wn6:E, 7wn6:G, 7wpp:E, 7wpp:G, 7wpq:A, 7wpq:B, 7wpq:E, 7wpq:G, 7wpr:A, 7wpr:B, 7wpr:E, 7wpr:F, 7wpr:G, 7wpr:H, 7wpr:I, 7wpr:J, 7wpr:K, 7wpr:L, 7wpr:M, 7wpr:N, 7wpr:O, 7wpr:P, 7wpr:Q, 7wpr:R, 7wps:A, 7wps:B, 7wps:E, 7wps:G, 7wps:I, 7wps:K, 7wps:M, 7wps:O, 7wps:Q, 7wps:S, 7wps:U, 7wps:W, 7wps:Y, 7wps:a, 7wqt:A, 7wqt:B, 7wqt:E, 7wqt:F, 7wqt:G, 7wqt:H, 7wqt:I, 7wqt:J, 7wqt:K, 7wqt:L, 7wqt:M, 7wqt:N, 7wqt:O, 7wqt:P, 7wqt:Q, 7wqt:R
13 8d3d:A 1314 390 0.2314 0.0875 0.2949 4.25e-28 8d3c:A, 8d3c:B, 8d3c:C, 8d3c:D, 8d3c:E, 8d3c:F, 8d3c:G, 8d3c:H, 8d3c:I, 8d3c:J, 8d3c:K, 8d3c:L, 8d3c:M, 8d3c:N, 8d3c:O, 8d3c:P, 8d3d:B, 8d3d:C, 8d3d:D, 8d3d:E, 8d3d:F, 8d3d:G, 8d3d:H, 8d3d:I, 8d3d:J, 8d3d:K, 8d3d:L, 8d3d:M, 8d3d:N, 8d3d:O, 8d3d:P, 7f49:A, 3hxo:A, 3hxq:A, 7wn3:A, 7wn3:B, 7wn3:E, 7wn3:G, 7wn4:E, 7wn4:G, 7wn6:A, 7wn6:B, 7wn6:E, 7wn6:G, 7wpp:E, 7wpp:G, 7wpq:A, 7wpq:B, 7wpq:E, 7wpq:G, 7wpr:A, 7wpr:B, 7wpr:E, 7wpr:F, 7wpr:G, 7wpr:H, 7wpr:I, 7wpr:J, 7wpr:K, 7wpr:L, 7wpr:M, 7wpr:N, 7wpr:O, 7wpr:P, 7wpr:Q, 7wpr:R, 7wps:A, 7wps:B, 7wps:E, 7wps:G, 7wps:I, 7wps:K, 7wps:M, 7wps:O, 7wps:Q, 7wps:S, 7wps:U, 7wps:W, 7wps:Y, 7wps:a, 7wqt:A, 7wqt:B, 7wqt:E, 7wqt:F, 7wqt:G, 7wqt:H, 7wqt:I, 7wqt:J, 7wqt:K, 7wqt:L, 7wqt:M, 7wqt:N, 7wqt:O, 7wqt:P, 7wqt:Q, 7wqt:R
14 7qcl:A 546 350 0.1811 0.1648 0.2571 1.08e-22 7qcl:B, 7qcn:A, 7qcn:B, 7qcu:A, 7qcu:B
15 8qci:B 269 266 0.1569 0.2900 0.2932 3.77e-22
16 8ov0:A 110 100 0.0805 0.3636 0.4000 1.56e-18
17 8s03:A 100 93 0.0805 0.4000 0.4301 8.04e-17
18 8oer:I 100 94 0.0785 0.3900 0.4149 6.78e-15 8oer:J, 8oes:I, 8oes:J, 8oes:K, 8oes:L, 8oes:M, 8oes:N
19 7rt0:A 385 72 0.0443 0.0571 0.3056 0.064
20 8sak:A 1121 50 0.0322 0.0143 0.3200 7.1

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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