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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
RAEEERIERWVEQLREALVGDGFLLHYQPVLNLQGEPLELYQAFLRLERNGEMMSPNAFMAIAEEHDLVTEIDRWVVARA
IRQLGERQRAGHKTHLLVRIGPNSFSDPQMIDTIREQLAVYGVPGERLWLQTPESKVFTHLRNAQQFLAAVSAMDCKVGL
EQFGSGLDSFQLLAHFHPAFLKLDRGITGDIASARDSQEKIREITSRAQPAGILTMAEFVADAQSMSSFFSAGVDYVQGD
FVAPTGPLMNYEFG

The query sequence (length=254) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 4fok:A 264 254 1.0000 0.9621 1.0000 0.0 4f3h:A, 4f48:A, 4foj:A, 4fou:A, 4fou:B, 7lkq:A
2 4afy:B 250 241 0.2835 0.2880 0.2988 3.94e-38 4afy:A, 4ag0:A, 4ag0:B, 3hv8:A
3 5xgd:A 548 239 0.2756 0.1277 0.2929 7.36e-25 8pps:A, 8pps:B, 5xge:A
4 4rnh:A 423 229 0.2559 0.1537 0.2838 7.46e-21
5 5m1t:A 247 231 0.2323 0.2389 0.2554 3.37e-19 5m1t:B
6 3n3t:B 261 236 0.2402 0.2337 0.2585 2.78e-16 3n3t:A, 2r6o:A, 2r6o:B
7 5m3c:B 426 242 0.2520 0.1502 0.2645 4.93e-16 5m3c:A
8 8arv:A 255 238 0.2165 0.2157 0.2311 6.38e-14 8arv:B
9 4hjf:A 263 225 0.2283 0.2205 0.2578 7.64e-14 3u2e:A, 3u2e:B
10 6hq7:A 377 238 0.2047 0.1379 0.2185 7.10e-13 6hq3:B, 6hq3:C, 6hq3:A, 6hq3:D, 6hq4:A, 6hq4:B, 6hq5:A, 6hq5:B, 6hq7:B
11 6pwj:A 408 226 0.2205 0.1373 0.2478 3.03e-12 6pwj:B, 6pwk:A, 6pwk:B
12 3pju:A 249 245 0.2441 0.2490 0.2531 1.16e-11 3pjt:A, 3pjt:B
13 5mf5:A 256 243 0.2244 0.2227 0.2346 1.45e-11 5mfu:A, 5mkg:A, 5mkg:B, 4y8e:A, 4y8e:B, 4y9p:A, 4y9p:B
14 6ifq:B 237 239 0.2126 0.2278 0.2259 2.75e-11 6ifq:A, 6ih1:A, 6ih1:B, 6ih1:C, 6ih1:D, 6ih7:B, 6ih7:A, 6ij2:A, 6ij2:B, 6ij2:C, 6ij2:D, 6k6t:A, 6k6t:B, 6k6t:C, 6k6t:D
15 5yrp:A 224 234 0.1929 0.2188 0.2094 7.71e-10 5yrp:B
16 3gfx:B 394 233 0.2047 0.1320 0.2232 7.12e-09 3gfx:A, 3gfz:A, 3gfz:B, 3gg0:A, 3gg0:B, 3gg1:A, 3gg1:B, 2kb2:A
17 3sy8:D 371 226 0.1811 0.1240 0.2035 7.77e-09
18 3sy8:B 392 226 0.1811 0.1173 0.2035 7.79e-09 3sy8:A, 3sy8:C
19 4lj3:A 256 238 0.1850 0.1836 0.1975 3.01e-04 4lj3:B, 4lyk:A, 4lyk:B, 4lyk:C, 4lyk:D
20 5g5v:A 335 43 0.0669 0.0507 0.3953 1.2 7a28:A, 7a28:B, 7a2f:A, 7a2f:B, 6fds:A, 6fds:B, 6fdw:A, 6fdw:B, 6fdx:A, 6fdx:B, 6fe3:A, 6fe3:B, 6frd:A, 6frd:B, 6ftm:A, 6ftm:B, 6fv9:A, 6fv9:B, 5g2b:A, 5g2b:B, 5g57:A, 5g57:B, 5g5v:B, 6gxq:A, 6gxq:B, 4i15:A, 4i15:B, 5l8c:A, 5l8c:B, 5l8y:A, 5l8y:B, 5l9h:A, 5l9h:B, 4phl:A, 4phl:B, 6qgp:A, 6qgp:B, 6qgu:A, 6qgu:B, 6rb6:A, 6rb6:B, 6rfn:A, 6rfn:B, 6rfw:A, 6rfw:B, 6rgk:A, 6rgk:B
21 7d4i:RP 2084 74 0.0866 0.0106 0.2973 1.2 7d5t:RP
22 2c1z:A 439 25 0.0512 0.0296 0.5200 2.3 2c1x:A, 2c9z:A
23 3gfy:B 374 89 0.0827 0.0561 0.2360 5.5 3gfy:A
24 4ys4:A 261 51 0.0591 0.0575 0.2941 9.6
25 4ku4:A 171 35 0.0512 0.0760 0.3714 9.9 4ku4:B
26 3r79:B 221 144 0.1378 0.1584 0.2431 9.9

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218