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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
QWPAPLANGGKSWASAFKKAKATVTEMTVEELANITSGVIGLCSGVTGAVTRLGIPEFCLQDGPIGPRGVHGSSQFPAGL
TVAATWDRTLMYARARGMGQEFHDQGVHLALAPVTGGPLGRTPLNGRGWEGTFADPYACGEASYLSVKGLTDAGVATVSK
HWIAYEQETSRNLYIDIDGVSQADIQLPISSNVDDLTMHELYMWSFAEAVRAGTNHIMCSYNRINNTHSCSNAKGLNQLL
KTELNFQGGVVSDWGGQWDSVPAAENGLDVAMPGKGFLGALGDFWGATLVELINNGTVSEDLVRDKAVRILTGYYYLGQD
TNPPPPFVYNTIGAPTLNATSGYRNVRKPGTAELIKEIGSASVTLLKNTGSLPLKHPQRIAVLGNDATYNVLGPNACGLA
NSACDIDNLNGTLTTGGGSGSALSPYTITPLEALQKRAIEDNAEIAAVVANSNTTTGAEDAIAALLPDADVTFVFLNRYS
EEGADAPDFSLGGDGDNLMDLAVTYSSNVVVVIHTTGVVDIEKWADNPNVTAILVAYLPGQEAGNSLVPVLYGDVAPSGK
LPWTWGKSIDDYVPNGVVYTDAYSPQSNFTEGVFIDYRWFDKMGITPRYEFGFGLSYTTFTYSNLIVDHGRWAKDYSSVM
ETAEPFAEWDGTNSLYDVIFTVFATITNTGNLTGSEVAQLYISIPGDNQPVRQLRGFDKIKDLPVGDSAVVTFPIRRKDV
SSWSVVDQLWYVPNGDFLISVGGSSRDLPLNTTWTP

The query sequence (length=756) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 6jbs:A 762 756 1.0000 0.9921 1.0000 0.0 7ey1:B, 7ey1:A, 7ey2:A, 7ey2:B, 7ey2:C, 7ey2:D, 7ey2:E, 7ey2:F, 7f95:A, 7f95:B, 8gyy:B, 8gyy:A, 8gyy:C, 8gyy:D, 6jbs:C, 6jbs:D, 6kj0:A, 6kj0:B, 7yo6:A, 7yo6:B, 7yo7:B, 7yo7:A
2 5fjj:A 839 677 0.3915 0.3528 0.4372 6.17e-165 5fjj:B, 5fjj:C, 5fjj:D
3 5fjj:A 839 103 0.0569 0.0513 0.4175 6.49e-14 5fjj:B, 5fjj:C, 5fjj:D
4 4iib:A 834 657 0.3796 0.3441 0.4368 5.02e-162 4iib:B, 4iic:A, 4iic:B, 4iid:A, 4iid:B, 4iie:A, 4iie:B, 4iif:A, 4iif:B, 4iig:A, 4iig:B, 4iih:A, 4iih:B
5 4iib:A 834 101 0.0529 0.0480 0.3960 2.55e-13 4iib:B, 4iic:A, 4iic:B, 4iid:A, 4iid:B, 4iie:A, 4iie:B, 4iif:A, 4iif:B, 4iig:A, 4iig:B, 4iih:A, 4iih:B
6 5fji:A 840 659 0.3889 0.3500 0.4461 5.52e-162 5fji:B
7 5fji:A 840 100 0.0595 0.0536 0.4500 3.51e-15 5fji:B
8 5ju6:A 835 649 0.3836 0.3473 0.4468 1.40e-161 5ju6:B, 5ju6:C, 5ju6:D
9 5ju6:A 835 106 0.0622 0.0563 0.4434 1.40e-15 5ju6:B, 5ju6:C, 5ju6:D
10 5nbs:A 842 655 0.3757 0.3373 0.4336 5.99e-160 5nbs:B
11 5nbs:A 842 100 0.0582 0.0523 0.4400 1.18e-15 5nbs:B
12 6sz6:A 836 652 0.3770 0.3409 0.4371 1.43e-157
13 6jxg:A 713 761 0.4048 0.4292 0.4021 1.98e-156
14 4i8d:B 714 763 0.3889 0.4118 0.3853 3.25e-154 4i8d:A, 3zyz:A
15 2x41:A 715 799 0.2923 0.3091 0.2766 2.66e-79 2x42:A
16 8j9f:D 749 756 0.2844 0.2870 0.2844 2.19e-76 8j9f:A, 8j9f:B
17 5wab:A 674 736 0.2765 0.3101 0.2840 2.33e-61
18 8c7f:A 772 745 0.2646 0.2591 0.2685 3.59e-48 7zb3:A, 7zb3:B, 7zdy:W, 7zdy:Y, 7zgz:Y
19 7zgz:X 753 736 0.2579 0.2590 0.2649 8.06e-47 8c7f:B
20 3u48:B 742 738 0.2513 0.2561 0.2575 1.25e-41 3u48:A, 3u4a:B, 3u4a:A
21 5tf0:A 733 750 0.2646 0.2729 0.2667 3.52e-40 5tf0:B
22 5xxm:A 749 742 0.2579 0.2603 0.2628 3.20e-36 5xxl:A, 5xxl:B, 5xxm:B, 5xxn:A, 5xxn:B, 5xxo:B, 5xxo:A
23 3ac0:A 841 411 0.1574 0.1415 0.2895 3.48e-33 3ac0:B, 3ac0:C, 3ac0:D
24 3ac0:A 841 337 0.1270 0.1141 0.2849 1.08e-22 3ac0:B, 3ac0:C, 3ac0:D
25 5z87:A 756 749 0.2447 0.2447 0.2470 1.18e-32 5z87:B
26 7vc7:A 743 741 0.2526 0.2571 0.2578 1.01e-31
27 4i3g:B 780 378 0.1521 0.1474 0.3042 1.53e-31 4i3g:A
28 4i3g:B 780 284 0.1124 0.1090 0.2993 1.61e-25 4i3g:A
29 6r5i:A 733 730 0.2381 0.2456 0.2466 6.58e-30 6r5i:B, 6r5n:B, 6r5n:A, 6r5o:B, 6r5o:A, 6r5p:B, 6r5p:A, 6r5r:B, 6r5r:A, 6r5t:B, 6r5t:A, 6r5u:B, 6r5u:A, 6r5v:B, 6r5v:A
30 7eap:A 755 749 0.2460 0.2464 0.2483 2.89e-29 5yot:A, 5yot:B, 5yqs:A, 5yqs:B
31 5jp0:A 745 749 0.2421 0.2456 0.2443 1.52e-28 5jp0:B
32 5ae6:B 767 770 0.2593 0.2555 0.2545 4.61e-28 5a7m:A, 5a7m:B, 5ae6:A
33 4zo6:B 724 732 0.2341 0.2445 0.2418 4.39e-26 4zo6:A, 4zo7:B, 4zo7:A, 4zo8:A, 4zo8:B, 4zo9:A, 4zo9:B, 4zoa:A, 4zoa:B, 4zob:A, 4zob:B, 4zoc:A, 4zoc:B, 4zod:A, 4zod:B, 4zoe:A, 4zoe:B
34 6q7i:A 770 752 0.2275 0.2234 0.2287 1.12e-21 6q7j:A, 6q7j:B
35 5wvp:A 924 224 0.0899 0.0736 0.3036 5.85e-19
36 5wvp:A 924 438 0.1508 0.1234 0.2603 4.12e-18
37 7xtj:B 743 775 0.2421 0.2463 0.2361 2.99e-18 7xtj:A
38 5m6g:A 579 588 0.1971 0.2573 0.2534 1.63e-17
39 5k6o:A 795 226 0.0847 0.0805 0.2832 1.21e-16 5k6m:A, 5k6n:A
40 5k6o:A 795 383 0.1283 0.1220 0.2533 1.40e-16 5k6m:A, 5k6n:A
41 6jg1:A 606 583 0.1825 0.2277 0.2367 2.89e-15 1ex1:A, 1ieq:A, 1iev:A, 1iew:A, 1iex:A, 1j8v:A, 6jg2:A, 6jg6:A, 6jg7:A, 6jga:A, 6jgb:A, 6jgc:A, 6jgd:A, 6jge:A, 6jgg:A, 6jgk:A, 6jgl:A, 6jgn:A, 6jgo:A, 6jgp:A, 6jgq:A, 6jgr:A, 6jgs:A, 6jgt:A, 6k6v:A, 6kuf:A, 6l1j:A, 6lbb:A, 6lbv:A, 6lc5:A, 1lq2:A, 6md6:A, 6mi1:A, 3wlh:A, 3wlj:A, 3wlk:X, 3wll:A, 3wlo:A, 3wlp:A, 1x38:A, 1x39:A
42 8xrt:F 751 345 0.1230 0.1238 0.2696 4.40e-14 8xrt:E, 8xrt:A, 8xrt:B, 8xrt:C, 8xrt:D, 8xru:A, 8xru:B, 8xrv:A, 8xrv:B, 8xrv:C, 8xrv:F, 8xrv:D, 8xrv:E, 8xrx:A, 8xrx:D, 8xrx:F, 8xrx:B, 8xrx:C
43 5z9s:A 765 375 0.1323 0.1307 0.2667 5.30e-14 5z9s:B
44 5z9s:A 765 226 0.0873 0.0863 0.2920 6.69e-09 5z9s:B
45 3ut0:A 804 595 0.1812 0.1704 0.2303 7.04e-12 3rrx:A, 3usz:A, 3ut0:B, 3ut0:C, 3ut0:D
46 8xrx:E 611 189 0.0661 0.0818 0.2646 2.11e-08
47 8xrx:E 611 213 0.0728 0.0900 0.2582 7.60e-07
48 6k5j:A 526 344 0.1071 0.1540 0.2355 6.14e-06
49 4gyj:A 618 283 0.0794 0.0971 0.2120 0.003 3bmx:A, 3bmx:B, 4gyj:B, 4gyk:A, 3nvd:A, 3nvd:B
50 6jtk:B 346 222 0.0648 0.1416 0.2207 0.20 6jtk:A, 6jtk:C, 6jtk:F, 6jtk:D, 6jtk:E
51 3whk:A 248 61 0.0278 0.0847 0.3443 4.1 3whk:B, 3whk:C, 3whk:D, 3whk:E, 3whk:F, 3whk:G, 3whk:H, 3whl:A, 3whl:C, 3whl:E, 3whl:G
52 4etj:A 164 110 0.0370 0.1707 0.2545 5.4 4jll:A
53 4bm1:A 337 98 0.0331 0.0742 0.2551 9.2 4bm1:B, 4bm2:A, 4bm3:A, 4bm4:A
54 2fav:B 171 65 0.0265 0.1170 0.3077 9.5
55 5eqt:A 249 35 0.0198 0.0602 0.4286 9.9

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218