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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
QVTVTKLGAHIGARIDGVRVGGDLSPATVSAINAALLEHKVIFFSGQDHLDDAGQLEFAELLGTPTANSWHTDVTFVDRI
PKASLLRAVTLPSYGGTTAWASTEAAYQQLPAPLRTLADNLWAVHTNRDYYEVEHPVVRVHPETGERVLLLGHFVKSFVG
LKDTESAALFRLFQDRITRLENTVRWSWKPGDLAIWDNRATQHYAVADYDDQYRRLNRVTLAGDIPVDVYGERSRVIAG

The query sequence (length=239) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 4j5i:E 250 240 1.0000 0.9560 0.9958 1.45e-175 4j5i:A, 4j5i:D, 4j5i:F, 4j5i:H
2 4j5i:B 285 275 1.0000 0.8386 0.8691 1.67e-168 4j5i:C, 4j5i:G
3 3r1j:A 246 239 0.6946 0.6748 0.6946 1.67e-117 3r1j:B
4 8evo:B 242 238 0.6736 0.6653 0.6765 1.01e-116 4cvy:A, 4cvy:B, 4cvy:C, 4cvy:D
5 3swt:B 246 239 0.6611 0.6423 0.6611 1.62e-114 3swt:A
6 4y0e:H 308 278 0.6736 0.5227 0.5791 5.86e-107 4y0e:A, 4y0e:B, 4y0e:C, 4y0e:D, 4y0e:E, 4y0e:F, 4y0e:G
7 1oij:C 238 236 0.6109 0.6134 0.6186 3.51e-97 1oii:C, 1oij:D
8 1vz4:D 259 254 0.6192 0.5714 0.5827 2.56e-95 1oii:A, 1oii:B, 1oii:D, 1oij:A, 1oij:B, 1oik:A, 1oik:D, 1vz4:A
9 5keu:B 280 267 0.4770 0.4071 0.4270 9.93e-55 5keu:A
10 3v17:A 276 275 0.4184 0.3623 0.3636 7.70e-45 3v17:C, 3v17:B, 3v17:D
11 6edh:A 281 276 0.4017 0.3416 0.3478 1.14e-43 6edh:B, 1gqw:A, 1gqw:B, 1gy9:A, 1gy9:B, 1os7:A, 1os7:B, 1os7:C, 1os7:D
12 7qte:B 284 250 0.3933 0.3310 0.3760 2.76e-41 7qtd:A, 7qtd:B, 7qtd:C, 7qtd:D, 7qte:A, 7qtg:A, 7qtg:B
13 6d3j:A 247 245 0.3305 0.3198 0.3224 7.43e-36
14 5vn6:A 273 273 0.3682 0.3223 0.3223 8.83e-35 5vn6:B
15 6d3h:M 287 280 0.3305 0.2753 0.2821 7.30e-31 6d3i:A
16 5bkc:B 264 260 0.3138 0.2841 0.2885 6.60e-30
17 6d0o:B 267 260 0.3180 0.2846 0.2923 1.03e-28
18 5bk9:A 289 280 0.3222 0.2664 0.2750 3.36e-27 5bk9:B, 5bkb:A, 5bkb:B, 5bkc:A, 5bkd:A, 5bkd:B, 6d0o:A, 6d0o:C, 6d0o:D, 6d3h:A, 6d3h:B, 6d3h:I, 6d3i:G, 6d3i:D, 6d3i:J, 6d3m:A, 6d3m:B, 6d3m:F, 6d3m:J
19 5j92:B 259 222 0.2594 0.2394 0.2793 2.42e-18 5j92:A, 5j92:C, 5j92:D
20 5bke:E 255 256 0.2845 0.2667 0.2656 5.31e-17 5bke:F, 5bke:G
21 5bke:C 289 288 0.2845 0.2353 0.2361 9.82e-13 5bke:A, 5bke:B, 5bke:D
22 6l86:A 292 267 0.2971 0.2432 0.2659 1.49e-12 6l86:B, 6l86:C, 6l86:D
23 6dch:A 296 242 0.2510 0.2027 0.2479 1.63e-08 6l6w:A, 6l6x:A, 7scp:A, 6xn6:A, 6xo3:A, 6xoj:A, 6xpa:A
24 8kht:B 285 221 0.1967 0.1649 0.2127 0.031 8kht:A
25 8kif:C 286 175 0.1674 0.1399 0.2286 0.25 8kif:B, 8kif:A, 8kif:D
26 4oj8:B 271 143 0.1674 0.1476 0.2797 0.25 1nx4:B, 1nx8:B, 4oj8:A, 4oj8:C
27 2vun:A 385 150 0.1423 0.0883 0.2267 0.30 2vun:B, 2vun:C, 2vun:D
28 6gna:A 284 114 0.1004 0.0845 0.2105 0.41 6gnb:A, 6gnd:A, 6gnd:C, 6gnd:E, 6gnd:G
29 6zwm:E 1117 62 0.0795 0.0170 0.3065 0.54 7pe7:F, 7pe7:E, 7pe8:E, 7pe9:E, 6zwm:F, 6zwo:F
30 1nx4:C 250 61 0.0879 0.0840 0.3443 0.69 1nx4:A, 1nx8:A, 1nx8:C
31 8hku:L10E 164 48 0.0586 0.0854 0.2917 2.5 8hkv:L10E, 8hky:L10E, 8hkz:L10E, 8hl1:L10E, 8hl2:L10E, 8hl3:L10E, 8hl4:L10E, 8hl5:L10E
32 2y27:B 427 112 0.1255 0.0703 0.2679 2.8 2y27:A, 2y4n:A, 2y4n:B
33 7r04:A 2326 26 0.0460 0.0047 0.4231 3.7
34 7pgr:N 2423 26 0.0460 0.0045 0.4231 3.7 2d4q:A, 2d4q:B, 2e2x:B, 3p7z:B, 3pg7:B, 7pgq:F, 7pgr:F, 7pgs:F, 7pgt:F, 7pgu:F, 7pgu:N
35 2cww:B 382 89 0.1213 0.0759 0.3258 3.9 2cww:A
36 5muy:A 327 57 0.0753 0.0550 0.3158 5.9 5muy:B
37 3kfu:C 377 73 0.0921 0.0584 0.3014 8.4 3kfu:A, 3kfu:D, 3kfu:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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