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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
QVPVSVNYHFSRKCNKECLFCFHTATTSHVEKPENAKRGLTLLKQAGMKKINFAGGEPFLYPKFLGEMIDFCKETLQLES
VSIVTNGSLVKEQFLQKHGRNIDILAVSCDSFNEATNIKIGRGSNVQKLYEIGSWCQKYDIKFKLNTVVNKFNHLEDMND
HLNALQPFRWKCFQVLIVTGENDSDKTLRNAHSLTISDDEFDRFCERHSSQTCLVPEPNRLMAKSYLILDEYMRFLDRNG
QQPSKSILEVGVQQALQAVFWDEEAFVERGGIYDWNKSS

The query sequence (length=279) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 7n7i:A 279 279 1.0000 1.0000 1.0000 0.0 7n7i:B, 7n7i:C
2 6q2p:B 293 285 0.5591 0.5324 0.5474 3.64e-111 6q2p:A, 6q2q:A, 6q2q:B, 5vsl:A, 5vsl:B, 5vsm:A, 5vsm:B
3 7n7h:A 289 285 0.5627 0.5433 0.5509 4.27e-111
4 8ai2:B 323 215 0.1935 0.1672 0.2512 6.65e-06 8ai1:A, 8ai1:B, 8ai2:A, 8ai3:A, 8ai3:B, 8ai4:A, 8ai4:B, 8ai5:A, 8ai5:B, 8ai6:A, 8ai6:B
5 7x0b:B 301 112 0.1183 0.1096 0.2946 7.33e-05 7wzv:A, 7wzv:B, 7wzx:A, 7x0b:A
6 5why:A 418 117 0.1004 0.0670 0.2393 4.05e-04
7 5wgg:A 440 116 0.0968 0.0614 0.2328 0.002 5why:B
8 7vob:C 327 148 0.1254 0.1070 0.2365 0.002 7voc:C
9 2fb2:A 327 149 0.1254 0.1070 0.2349 0.006 2fb2:B, 2fb3:A, 2fb3:B, 1tv7:A, 1tv7:B, 1tv8:A, 1tv8:B
10 7tom:A 498 130 0.1290 0.0723 0.2769 0.034 7tol:A
11 6efn:A 383 65 0.0645 0.0470 0.2769 0.054
12 3t7v:A 337 94 0.0932 0.0772 0.2766 0.059
13 4k36:A 381 159 0.1362 0.0997 0.2390 0.72 4k36:B, 4k37:A, 4k37:B, 4k38:B, 4k38:A, 4k39:B, 4k39:A
14 8juj:B 380 85 0.0789 0.0579 0.2588 0.79 8juj:A
15 4zrn:A 309 75 0.0753 0.0680 0.2800 0.85 4zrm:A, 4zrm:B, 4zrn:B
16 3apt:A 292 73 0.0860 0.0822 0.3288 0.87 3apy:A, 3apy:B, 3apy:C, 3apy:D, 3apy:E, 3apy:F, 3apy:G, 3apy:H, 8eac:A, 7th4:A, 7th4:B, 7th5:A, 7th5:B, 1v93:A
17 7o1o:A 356 99 0.0860 0.0674 0.2424 2.4 3ciw:A, 3cix:A, 5fep:A, 5fes:A, 5few:A, 5fex:A, 5fez:A, 5ff0:A, 5ff2:A, 5ff3:A, 5ff4:A, 3iix:A, 3iiz:A, 4jxc:A, 4jy8:A, 4jy9:A, 4jyd:A, 4jye:A, 4jyf:A, 7o1p:A, 7o1s:A, 7o1t:A, 7o25:A, 7o26:A, 8qmk:A, 8qml:A, 8qmm:A, 8qmn:A
18 7ufg:B 1182 60 0.0609 0.0144 0.2833 3.5 8d8o:B
19 6inh:A 450 73 0.0681 0.0422 0.2603 6.7 6inf:A, 6ing:A, 6ini:A, 6kvi:A, 6kvj:A, 6kvk:A, 6kvl:A, 6o86:A, 6o87:A, 6o88:A
20 5fgp:A 144 51 0.0502 0.0972 0.2745 7.4
21 7xg0:D 331 77 0.0824 0.0695 0.2987 7.5 7xfz:C, 7xg0:C, 7xg0:E, 7xg0:F, 7xg1:C, 7xg1:D, 7xg1:E, 7xg2:C, 7xg2:D, 7xg2:E, 7xg2:F, 7xg3:C, 7xg3:D, 7xg3:E, 7xg3:F, 7xg4:C, 7xg4:D, 7xg4:E, 7xg4:F
22 3axb:A 428 23 0.0394 0.0257 0.4783 7.8 3vqr:A, 3vqr:B
23 7xg1:F 287 77 0.0824 0.0801 0.2987 8.0 7xfz:D, 7xg0:G, 7xg2:G, 7xg3:G, 7xg4:G
24 8sl1:A 843 88 0.0789 0.0261 0.2500 8.4
25 1kc5:L 214 35 0.0466 0.0607 0.3714 9.8 1kcr:L

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218